-
1
-
-
4444309565
-
The complex life of simple sphingolipids
-
DOI 10.1038/sj.embor.7400208
-
Futerman A. H., Hannun Y. A., The complex life of simple sphingolipids. EMBO Reports 2004 5 8 777 782 2-s2.0-4444309565 10.1038/sj.embor.7400208 (Pubitemid 39199166)
-
(2004)
EMBO Reports
, vol.5
, Issue.8
, pp. 777-782
-
-
Futerman, A.H.1
Hannun, Y.A.2
-
2
-
-
1542320683
-
Lipid metabolism: Ceramide transfer protein adds a new dimension
-
DOI 10.1016/S0960-9822(04)00079-X, PII S096098220400079X
-
Hannun Y. A., Luberto C., Lipid metabolism: ceramide transfer protein adds a new dimension. Current Biology 2004 14 4 R163 R165 2-s2.0-1542320683 10.1016/S0960-9822(04)00079-X (Pubitemid 38300202)
-
(2004)
Current Biology
, vol.14
, Issue.4
-
-
Hannun, Y.A.1
Luberto, C.2
-
3
-
-
0037201970
-
Sphingosine-1-phosphate: Dual messenger functions
-
DOI 10.1016/S0014-5793(02)03480-4, PII S0014579302034804
-
Payne S. G., Milstien S., Spiegel S., Sphingosine-1-phosphate: dual messenger functions. FEBS Letters 2002 531 1 54 57 2-s2.0-0037201970 10.1016/S0014-5793(02)03480-4 (Pubitemid 35232784)
-
(2002)
FEBS Letters
, vol.531
, Issue.1
, pp. 54-57
-
-
Payne, S.G.1
Milstien, S.2
Spiegel, S.3
-
5
-
-
84862860884
-
Functional roles of gangliosides in neurodevelopment: An overview of recent advances
-
2-s2.0-84857946706 10.1007/s11064-012-0744-y
-
Yu R. K., Tsai Y.-T., Ariga T., Functional roles of gangliosides in neurodevelopment: an overview of recent advances. Neurochemical Research 2012 37 6 1230 1244 2-s2.0-84857946706 10.1007/s11064-012-0744-y
-
(2012)
Neurochemical Research
, vol.37
, Issue.6
, pp. 1230-1244
-
-
Yu, R.K.1
Tsai, Y.-T.2
Ariga, T.3
-
6
-
-
80051514415
-
Many ceramides
-
2-s2.0-80051514415 10.1074/jbc.R111.254359
-
Hannun Y. A., Obeid L. M., Many ceramides. Journal of Biological Chemistry 2011 286 32 27855 27862 2-s2.0-80051514415 10.1074/jbc.R111.254359
-
(2011)
Journal of Biological Chemistry
, vol.286
, Issue.32
, pp. 27855-27862
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
7
-
-
0026712872
-
Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N- acyltransferase in mouse liver
-
2-s2.0-0026712872
-
Mandon E. C., Ehses I., Rother J., van Echten G., Sandhoff K., Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphinganine N- acyltransferase in mouse liver. Journal of Biological Chemistry 1992 267 16 11144 11148 2-s2.0-0026712872
-
(1992)
Journal of Biological Chemistry
, vol.267
, Issue.16
, pp. 11144-11148
-
-
Mandon, E.C.1
Ehses, I.2
Rother, J.3
Van Echten, G.4
Sandhoff, K.5
-
8
-
-
0028136956
-
Occurrence of two molecular forms of human acid sphingomyelinase
-
Ferinz K., Hurwitz R., Vielhaber G., Suzuki K., Sandhoff K., Occurrence of two molecular forms of human acid sphingomyelinase. Biochemical Journal 1994 301 3 855 862 2-s2.0-0028136956 (Pubitemid 24239322)
-
(1994)
Biochemical Journal
, vol.301
, Issue.3
, pp. 855-862
-
-
Ferinz, K.1
Hurwitz, R.2
Vielhaber, G.3
Suzuki, K.4
Sandhoff, K.5
-
9
-
-
78650052094
-
Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function
-
2-s2.0-78650052094 10.1074/jbc.M110.139287
-
Perrotta C., Bizzozero L., Cazzato D., Morlacchi S., Assi E., Simbari F., Zhang Y., Gulbins E., Bassi M. T., Rosa P., Clementi E., Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function. Journal of Biological Chemistry 2010 285 51 40240 40251 2-s2.0-78650052094 10.1074/jbc.M110.139287
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.51
, pp. 40240-40251
-
-
Perrotta, C.1
Bizzozero, L.2
Cazzato, D.3
Morlacchi, S.4
Assi, E.5
Simbari, F.6
Zhang, Y.7
Gulbins, E.8
Bassi, M.T.9
Rosa, P.10
Clementi, E.11
-
10
-
-
0042335762
-
Ceramide-mediated clustering is required for CD95-DISC formation
-
DOI 10.1038/sj.onc.1206540
-
Grassmé H., Cremesti A., Kolesnick R., Gulbins E., Ceramide-mediated clustering is required for CD95-DISC formation. Oncogene 2003 22 35 5457 5470 2-s2.0-0042335762 10.1038/sj.onc.1206540 (Pubitemid 37072201)
-
(2003)
Oncogene
, vol.22
, Issue.35
, pp. 5457-5470
-
-
Grassme, H.1
Cremesti, A.2
Kolesnick, R.3
Gulbins, E.4
-
11
-
-
33947363813
-
Analysis of membrane topology of neutral sphingomyelinase 2
-
DOI 10.1016/j.febslet.2007.02.046, PII S0014579307002141
-
Tani M., Hannun Y. A., Analysis of membrane topology of neutral sphingomyelinase 2. FEBS Letters 2007 581 7 1323 1328 2-s2.0-33947363813 10.1016/j.febslet.2007.02.046 (Pubitemid 46452606)
-
(2007)
FEBS Letters
, vol.581
, Issue.7
, pp. 1323-1328
-
-
Tani, M.1
Hannun, Y.A.2
-
12
-
-
77951913548
-
Biological roles of acid and neutral sphingomyelinases and their regulation by nitric oxide
-
2-s2.0-77951913548 10.1152/physiol.00048.2009
-
Perrotta C., Clementi E., Biological roles of acid and neutral sphingomyelinases and their regulation by nitric oxide. Physiology 2010 25 2 64 71 2-s2.0-77951913548 10.1152/physiol.00048.2009
-
(2010)
Physiology
, vol.25
, Issue.2
, pp. 64-71
-
-
Perrotta, C.1
Clementi, E.2
-
13
-
-
42249105215
-
The sphingolipid salvage pathway in ceramide metabolism and signaling
-
2-s2.0-42249105215 10.1016/j.cellsig.2007.12.006
-
Kitatani K., Idkowiak-Baldys J., Hannun Y. A., The sphingolipid salvage pathway in ceramide metabolism and signaling. Cellular Signalling 2008 20 6 1010 1018 2-s2.0-42249105215 10.1016/j.cellsig.2007.12.006
-
(2008)
Cellular Signalling
, vol.20
, Issue.6
, pp. 1010-1018
-
-
Kitatani, K.1
Idkowiak-Baldys, J.2
Hannun, Y.A.3
-
16
-
-
0038218405
-
Sphingosine-1-phosphate: An enigmatic signalling lipid
-
DOI 10.1038/nrm1103
-
Spiegel S., Milstien S., Sphingosine-1-phosphate: an enigmatic signalling lipid. Nature Reviews Molecular Cell Biology 2003 4 5 397 407 2-s2.0-0038218405 10.1038/nrm1103 (Pubitemid 36565571)
-
(2003)
Nature Reviews Molecular Cell Biology
, vol.4
, Issue.5
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
-
17
-
-
79961082952
-
Translational aspects of sphingosine 1-phosphate biology
-
2-s2.0-79961082952 10.1016/j.molmed.2011.03.002
-
Pyne S., Pyne N. J., Translational aspects of sphingosine 1-phosphate biology. Trends in Molecular Medicine 2011 17 8 463 472 2-s2.0-79961082952 10.1016/j.molmed.2011.03.002
-
(2011)
Trends in Molecular Medicine
, vol.17
, Issue.8
, pp. 463-472
-
-
Pyne, S.1
Pyne, N.J.2
-
18
-
-
40849119996
-
Structure and function of glycosphingolipids and sphingolipids: Recollections and future trends
-
DOI 10.1016/j.bbagen.2007.08.015, PII S0304416507001870
-
Hakomori S.-I., Structure and function of glycosphingolipids and sphingolipids: recollections and future trends. Biochimica et Biophysica Acta 2008 1780 3 325 346 2-s2.0-40849119996 10.1016/j.bbagen.2007.08.015 (Pubitemid 351395304)
-
(2008)
Biochimica et Biophysica Acta - General Subjects
, vol.1780
, Issue.3
, pp. 325-346
-
-
Hakomori, S.-i.1
-
19
-
-
38449104148
-
Glycosylation of glycolipids in the Golgi complex
-
supplement 1 2-s2.0-38449104148 10.1111/j.1471-4159.2007.04717.x
-
Maccioni H. J. F., Glycosylation of glycolipids in the Golgi complex. Journal of Neurochemistry 2007 103 supplement 1 81 90 2-s2.0-38449104148 10.1111/j.1471-4159.2007.04717.x
-
(2007)
Journal of Neurochemistry
, vol.103
, pp. 81-90
-
-
Maccioni, H.J.F.1
-
20
-
-
0031692336
-
The caveolae membrane system
-
DOI 10.1146/annurev.biochem.67.1.199
-
Anderson R. G. W., The caveolae membrane system. Annual Review of Biochemistry 1998 67 199 225 2-s2.0-0031692336 10.1146/annurev.biochem.67.1.199 (Pubitemid 28411129)
-
(1998)
Annual Review of Biochemistry
, vol.67
, pp. 199-225
-
-
Anderson, R.G.W.1
-
21
-
-
0036733578
-
Cholesterol, lipid rafts, and disease
-
DOI 10.1172/JCI200216390
-
Simons K., Ehehalt R., Cholesterol, lipid rafts, and disease. Journal of Clinical Investigation 2002 110 5 597 603 2-s2.0-0036733578 10.1172/JCI200216390 (Pubitemid 34988781)
-
(2002)
Journal of Clinical Investigation
, vol.110
, Issue.5
, pp. 597-603
-
-
Simons, K.1
Ehehalt, R.2
-
22
-
-
0031667314
-
New insights in glycosphingolipid function: "glycosignaling domain," a cell surface assembly of glycosphingolipids with signal transducer molecules, involved in cell adhesion coupled with signaling
-
2-s2.0-0031667314
-
Hakomori S.-I., Handa K., Iwabuchi K., Yamamura S., Prinetti A., New insights in glycosphingolipid function: "glycosignaling domain," a cell surface assembly of glycosphingolipids with signal transducer molecules, involved in cell adhesion coupled with signaling. Glycobiology 1998 8 10 11 18 2-s2.0-0031667314
-
(1998)
Glycobiology
, vol.8
, Issue.10
, pp. 11-18
-
-
Hakomori, S.-I.1
Handa, K.2
Iwabuchi, K.3
Yamamura, S.4
Prinetti, A.5
-
23
-
-
58849160520
-
Ceramide and neurodegeneration: Susceptibility of neurons and oligodendrocytes to cell damage and death
-
2-s2.0-58849160520 10.1016/j.jns.2008.12.010
-
Jana A., Hogan E. L., Pahan K., Ceramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death. Journal of the Neurological Sciences 2009 278 1-2 5 15 2-s2.0-58849160520 10.1016/j.jns.2008.12.010
-
(2009)
Journal of the Neurological Sciences
, vol.278
, Issue.1-2
, pp. 5-15
-
-
Jana, A.1
Hogan, E.L.2
Pahan, K.3
-
24
-
-
84872284081
-
Ceramide function in the brain: When a slight tilt is enough
-
10.1007/s00018-012-1038-x
-
Mencarelli C., Martinez-Martinez P., Ceramide function in the brain: when a slight tilt is enough. Cellular and Molecular Life Sciences 2013 70 2 181 203 10.1007/s00018-012-1038-x
-
(2013)
Cellular and Molecular Life Sciences
, vol.70
, Issue.2
, pp. 181-203
-
-
Mencarelli, C.1
Martinez-Martinez, P.2
-
25
-
-
84892867432
-
Sphingolipids in neuroinflammation
-
Springer Handbook of Experimental Pharmacology 10.1007/978-3-7091-1511-4- 21
-
Davies L., Fassbender K., Walter S., Sphingolipids in neuroinflammation. Sphingolipids in Disease 2013 216 Springer 421 430 Handbook of Experimental Pharmacology 10.1007/978-3-7091-1511-4-21
-
(2013)
Sphingolipids in Disease
, vol.216
, pp. 421-430
-
-
Davies, L.1
Fassbender, K.2
Walter, S.3
-
26
-
-
78649790233
-
Sphingolipids in neurodegeneration
-
2-s2.0-78649790233 10.1007/s12017-010-8135-5
-
Haughey N. J., Sphingolipids in neurodegeneration. NeuroMolecular Medicine 2010 12 4 301 305 2-s2.0-78649790233 10.1007/s12017-010-8135-5
-
(2010)
NeuroMolecular Medicine
, vol.12
, Issue.4
, pp. 301-305
-
-
Haughey, N.J.1
-
27
-
-
77955088249
-
Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders
-
2-s2.0-77955088249 10.1007/s12035-009-8096-6
-
Piccinini M., Scandroglio F., Prioni S., Buccinnà B., Loberto N., Aureli M., Chigorno V., Lupino E., DeMarco G., Lomartire A., Rinaudo M. T., Sonnino S., Prinetti A., Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders. Molecular Neurobiology 2010 41 2-3 314 340 2-s2.0-77955088249 10.1007/s12035-009-8096-6
-
(2010)
Molecular Neurobiology
, vol.41
, Issue.2-3
, pp. 314-340
-
-
Piccinini, M.1
Scandroglio, F.2
Prioni, S.3
Buccinnà, B.4
Loberto, N.5
Aureli, M.6
Chigorno, V.7
Lupino, E.8
Demarco, G.9
Lomartire, A.10
Rinaudo, M.T.11
Sonnino, S.12
Prinetti, A.13
-
28
-
-
84864765533
-
Microglia and mast cells: Two tracks on the road to neuroinflammation
-
10.1096/fj.11-197194
-
Skaper S. D., Giusti P., Facci L., Microglia and mast cells: two tracks on the road to neuroinflammation. The FASEB Journal 2012 26 8 3103 3117 10.1096/fj.11-197194
-
(2012)
The FASEB Journal
, vol.26
, Issue.8
, pp. 3103-3117
-
-
Skaper, S.D.1
Giusti, P.2
Facci, L.3
-
29
-
-
84865049615
-
Sphingolipids: Critical players in Alzheimer's disease
-
10.1016/j.plipres.2012.07.001
-
van Echten-Deckert G., Walter J., Sphingolipids: critical players in Alzheimer's disease. Progress in Lipid Research 2012 51 4 378 393 10.1016/j.plipres.2012.07.001
-
(2012)
Progress in Lipid Research
, vol.51
, Issue.4
, pp. 378-393
-
-
Van Echten-Deckert, G.1
Walter, J.2
-
31
-
-
0035412093
-
Activated microglia: The silent executioner in neurodegenerative disease?
-
2-s2.0-0035412093
-
Appel S. H., Simpson E. P., Activated microglia: the silent executioner in neurodegenerative disease? Current Neurology and Neuroscience Reports 2001 1 4 303 305 2-s2.0-0035412093
-
(2001)
Current Neurology and Neuroscience Reports
, vol.1
, Issue.4
, pp. 303-305
-
-
Appel, S.H.1
Simpson, E.P.2
-
32
-
-
84866103622
-
Neurodegenerative disease: Microglia in early disease stages
-
10.1038/nrneurol.2012.172
-
Kingwell K., Neurodegenerative disease: microglia in early disease stages. Nature Reviews Neurology 2012 8 9 475 10.1038/nrneurol.2012.172
-
(2012)
Nature Reviews Neurology
, vol.8
, Issue.9
, pp. 475
-
-
Kingwell, K.1
-
33
-
-
77950858637
-
Microglia in neurodegenerative disease
-
2-s2.0-77950858637 10.1038/nrneurol.2010.17
-
Perry V. H., Nicoll J. A. R., Holmes C., Microglia in neurodegenerative disease. Nature Reviews Neurology 2010 6 4 193 201 2-s2.0-77950858637 10.1038/nrneurol.2010.17
-
(2010)
Nature Reviews Neurology
, vol.6
, Issue.4
, pp. 193-201
-
-
Perry, V.H.1
Nicoll, J.A.R.2
Holmes, C.3
-
34
-
-
58149141584
-
Neuroprotective and toxic changes in microglia in neurodegenerative disease
-
supplement 1 2-s2.0-58149141584 10.1016/S1353-8020(09)70011-2
-
Sawada M., Neuroprotective and toxic changes in microglia in neurodegenerative disease. Parkinsonism and Related Disorders 2009 15 supplement 1 S39 S41 2-s2.0-58149141584 10.1016/S1353-8020(09)70011-2
-
(2009)
Parkinsonism and Related Disorders
, vol.15
-
-
Sawada, M.1
-
35
-
-
34247330919
-
Modulation of inflammation in brain: A matter of fat
-
DOI 10.1111/j.1471-4159.2006.04371.x
-
Farooqui A. A., Horrocks L. A., Farooqui T., Modulation of inflammation in brain: a matter of fat. Journal of Neurochemistry 2007 101 3 577 599 2-s2.0-34247330919 10.1111/j.1471-4159.2006.04371.x (Pubitemid 46633316)
-
(2007)
Journal of Neurochemistry
, vol.101
, Issue.3
, pp. 577-599
-
-
Farooqui, A.A.1
Horrocks, L.A.2
Farooqui, T.3
-
36
-
-
79955605102
-
Physiology of microglia
-
2-s2.0-79955605102 10.1152/physrev.00011.2010
-
Helmut K., Hanisch U.-K., Noda M., Verkhratsky A., Physiology of microglia. Physiological Reviews 2011 91 2 461 553 2-s2.0-79955605102 10.1152/physrev.00011.2010
-
(2011)
Physiological Reviews
, vol.91
, Issue.2
, pp. 461-553
-
-
Helmut, K.1
Hanisch, U.-K.2
Noda, M.3
Verkhratsky, A.4
-
37
-
-
67650966680
-
Microglial physiology: Unique stimuli, specialized responses
-
2-s2.0-67650966680 10.1146/annurev.immunol.021908.132528
-
Ransohoff R. M., Perry V. H., Microglial physiology: unique stimuli, specialized responses. Annual Review of Immunology 2009 27 119 145 2-s2.0-67650966680 10.1146/annurev.immunol.021908.132528
-
(2009)
Annual Review of Immunology
, vol.27
, pp. 119-145
-
-
Ransohoff, R.M.1
Perry, V.H.2
-
38
-
-
80355143546
-
Microglial cell origin and phenotypes in health and disease
-
2-s2.0-80355143546 10.1038/nri3086
-
Saijo K., Glass C. K., Microglial cell origin and phenotypes in health and disease. Nature Reviews Immunology 2011 11 11 775 787 2-s2.0-80355143546 10.1038/nri3086
-
(2011)
Nature Reviews Immunology
, vol.11
, Issue.11
, pp. 775-787
-
-
Saijo, K.1
Glass, C.K.2
-
39
-
-
33646516647
-
Gangliosides trigger inflammatory responses via TLR4 in brain glia
-
2-s2.0-33646516647 10.2353/ajpath.2006.050924
-
Jou I., Lee J. H., Park S. Y., Yoon H. J., Joe E.-H., Park E. J., Gangliosides trigger inflammatory responses via TLR4 in brain glia. American Journal of Pathology 2006 168 5 1619 1630 2-s2.0-33646516647 10.2353/ajpath.2006.050924
-
(2006)
American Journal of Pathology
, vol.168
, Issue.5
, pp. 1619-1630
-
-
Jou, I.1
Lee, J.H.2
Park, S.Y.3
Yoon, H.J.4
Joe, E.-H.5
Park, E.J.6
-
40
-
-
0030697366
-
Reactive astrocytes: Cellular and molecular cues to biological function
-
DOI 10.1016/S0166-2236(97)01139-9
-
Ridet J. L., Malhotra S. K., Privat A., Gage F. H., Reactive astrocytes: cellular and molecular cues to biological function. Trends in Neurosciences 1997 20 12 570 577 2-s2.0-0030697366 10.1016/S0166-2236(97)01139-9 (Pubitemid 27508969)
-
(1997)
Trends in Neurosciences
, vol.20
, Issue.12
, pp. 570-577
-
-
Ridet, J.L.1
Malhotra, S.K.2
Privat, A.3
Gage, F.H.4
-
41
-
-
0031874792
-
Inflammation in the CNS: Balance between immunological privilege and immune responses
-
DOI 10.1016/S0301-0082(98)00014-8, PII S0301008298000148
-
Matyszak M. K., Inflammation in the CNS: balance between immunological privilege and immune responses. Progress in Neurobiology 1998 56 1 19 35 2-s2.0-0031874792 10.1016/S0301-0082(98)00014-8 (Pubitemid 28351160)
-
(1998)
Progress in Neurobiology
, vol.56
, Issue.1
, pp. 19-35
-
-
Matyszak, M.K.1
-
42
-
-
78751700548
-
Microglia/macrophages promote glioma progression
-
2-s2.0-78751700548 10.1002/glia.21117
-
Zhai H., Heppner F. L., Tsirka S. E., Microglia/macrophages promote glioma progression. GLIA 2011 59 3 472 485 2-s2.0-78751700548 10.1002/glia.21117
-
(2011)
GLIA
, vol.59
, Issue.3
, pp. 472-485
-
-
Zhai, H.1
Heppner, F.L.2
Tsirka, S.E.3
-
43
-
-
70449717860
-
Are circulating monocytes as microglia orthologues appropriate biomarker targets for neuronal diseases?
-
2-s2.0-70449717860
-
Schmitz G., Leuthäuser-Jaschinski K., Orsó E., Are circulating monocytes as microglia orthologues appropriate biomarker targets for neuronal diseases? Central Nervous System Agents in Medicinal Chemistry 2009 9 4 307 330 2-s2.0-70449717860
-
(2009)
Central Nervous System Agents in Medicinal Chemistry
, vol.9
, Issue.4
, pp. 307-330
-
-
Schmitz, G.1
Leuthäuser-Jaschinski, K.2
Orsó, E.3
-
44
-
-
0035865406
-
Brain dendritic cells and macrophages/microglia in central nervous system inflammation
-
Fischer H.-G., Reichmann G., Brain dendritic cells and macrophages/microglia in central nervous system inflammation. Journal of Immunology 2001 166 4 2717 2726 2-s2.0-0035865406 (Pubitemid 32173513)
-
(2001)
Journal of Immunology
, vol.166
, Issue.4
, pp. 2717-2726
-
-
Fischer, H.-G.1
Reichmann, G.2
-
45
-
-
80355131976
-
Protective and pathogenic functions of macrophage subsets
-
2-s2.0-80355131976 10.1038/nri3073
-
Murray P. J., Wynn T. A., Protective and pathogenic functions of macrophage subsets. Nature Reviews Immunology 2011 11 11 723 737 2-s2.0-80355131976 10.1038/nri3073
-
(2011)
Nature Reviews Immunology
, vol.11
, Issue.11
, pp. 723-737
-
-
Murray, P.J.1
Wynn, T.A.2
-
46
-
-
33748047499
-
Bioactive sphingolipids in the modulation of the inflammatory response
-
DOI 10.1016/j.pharmthera.2006.04.004, PII S016372580600060X
-
El Alwani M., Wu B. X., Obeid L. M., Hannun Y. A., Bioactive sphingolipids in the modulation of the inflammatory response. Pharmacology and Therapeutics 2006 112 1 171 183 2-s2.0-33748047499 10.1016/j.pharmthera.2006.04. 004 (Pubitemid 44301491)
-
(2006)
Pharmacology and Therapeutics
, vol.112
, Issue.1
, pp. 171-183
-
-
El Alwani, M.1
Wu, B.X.2
Obeid, L.M.3
Hannun, Y.A.4
-
47
-
-
70350133784
-
Sphingolipids in inflammation: Pathological implications and potential therapeutic targets
-
2-s2.0-70350133784 10.1111/j.1476-5381.2009.00281.x
-
Nixon G. F., Sphingolipids in inflammation: pathological implications and potential therapeutic targets. British Journal of Pharmacology 2009 158 4 982 993 2-s2.0-70350133784 10.1111/j.1476-5381.2009.00281.x
-
(2009)
British Journal of Pharmacology
, vol.158
, Issue.4
, pp. 982-993
-
-
Nixon, G.F.1
-
48
-
-
0032493829
-
Cytokine-mediated induction of ceramide production is redox-sensitive: Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases
-
DOI 10.1074/jbc.273.32.20354
-
Singh I., Pahan K., Khan M., Singh A. K., Cytokine-mediated induction of ceramide production is redox-sensitive: implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases. Journal of Biological Chemistry 1998 273 32 20354 20362 2-s2.0-0032493829 10.1074/jbc.273.32.20354 (Pubitemid 28377600)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.32
, pp. 20354-20362
-
-
Singh, I.1
Pahan, K.2
Khan, M.3
Singh, A.K.4
-
49
-
-
0347122965
-
Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway
-
DOI 10.1083/jcb.200307017
-
Lee J.-T., Xu J., Lee J.-M., Ku G., Han X., Yang D.-I., Chen S., Hsu C. Y., Amyloid- β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway. Journal of Cell Biology 2004 164 1 123 131 2-s2.0-0347122965 10.1083/jcb.200307017 (Pubitemid 38082463)
-
(2004)
Journal of Cell Biology
, vol.164
, Issue.1
, pp. 123-131
-
-
Lee, J.-T.1
Xu, J.2
Lee, J.-M.3
Ku, G.4
Han, X.5
Yang, D.-I.6
Chen, S.7
Hsu, C.Y.8
-
50
-
-
0032579511
-
Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in Rat primary astrocytes
-
DOI 10.1074/jbc.273.5.2591
-
Pahan K., Sheikh F. G., Khan M., Namboodiri A. M. S., Singh I., Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes. Journal of Biological Chemistry 1998 273 5 2591 2600 2-s2.0-0032579511 10.1074/jbc.273.5.2591 (Pubitemid 28133900)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.5
, pp. 2591-2600
-
-
Pahan, K.1
Sheikh, F.G.2
Khan, M.3
Namboodiri, A.M.S.4
Singh, I.5
-
51
-
-
0942287672
-
The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase
-
DOI 10.1046/j.1471-4159.2003.02165.x
-
Won J.-S., Im Y.-B., Khan M., Singh A. K., Singh I., The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase. Journal of Neurochemistry 2004 88 3 583 593 2-s2.0-0942287672 10.1046/j.1471-4159.2003.02165.x (Pubitemid 38140203)
-
(2004)
Journal of Neurochemistry
, vol.88
, Issue.3
, pp. 583-593
-
-
Won, J.-S.1
Im, Y.-B.2
Khan, M.3
Singh, A.K.4
Singh, I.5
-
52
-
-
38549152194
-
Principles of bioactive lipid signalling: Lessons from sphingolipids
-
DOI 10.1038/nrm2329, PII NRM2329
-
Hannun Y. A., Obeid L. M., Principles of bioactive lipid signalling: lessons from sphingolipids. Nature Reviews Molecular Cell Biology 2008 9 2 139 150 2-s2.0-38549152194 10.1038/nrm2329 (Pubitemid 351158911)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.2
, pp. 139-150
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
53
-
-
0039778363
-
The p75(NTR)-induced apoptotic program develops through a ceramide- caspase pathway negatively regulated by nitric oxide
-
DOI 10.1074/jbc.274.22.15466
-
Lièvremont J.-P., Sciorati C., Morandi E., Paolucci C., Bunone G., Della Valle G., Meldolesi J., Clementi E., The p75(NTR)-induced apoptotic program develops through a ceramide- caspase pathway negatively regulated by nitric oxide. Journal of Biological Chemistry 1999 274 22 15466 15472 2-s2.0-0039778363 10.1074/jbc.274.22.15466 (Pubitemid 29254912)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.22
, pp. 15466-15472
-
-
Lievremont, J.-P.1
Sciorati, C.2
Morandi, E.3
Paolucci, C.4
Bunone, G.5
Della Valle, G.6
Meldolesi, J.7
Clementi, E.8
-
54
-
-
84878491154
-
Phospholipids and Alzheimer's disease: Alterations, mechanisms and potential biomarkers
-
10.3390/ijms14011310
-
Kosicek M., Hecimovic S., Phospholipids and Alzheimer's disease: alterations, mechanisms and potential biomarkers. International Journal of Molecular Sciences 2013 14 1 1310 1322 10.3390/ijms14011310
-
(2013)
International Journal of Molecular Sciences
, vol.14
, Issue.1
, pp. 1310-1322
-
-
Kosicek, M.1
Hecimovic, S.2
-
55
-
-
1242338183
-
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease
-
DOI 10.1073/pnas.0305799101
-
Cutler R. G., Kelly J., Storie K., Pedersen W. A., Tammara A., Hatanpaa K., Troncoso J. C., Mattson M. P., Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America 2004 101 7 2070 2075 2-s2.0-1242338183 10.1073/pnas.0305799101 (Pubitemid 38229016)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.7
, pp. 2070-2075
-
-
Cutler, R.G.1
Kelly, J.2
Storie, K.3
Pedersen, W.A.4
Tammara, A.5
Hatanpaa, K.6
Troncoso, J.C.7
Mattson, M.P.8
-
56
-
-
0042508791
-
Neuropathologic changes in Alzheimer's disease
-
Wenk G. L., Neuropathologic changes in Alzheimer's disease. Journal of Clinical Psychiatry 2003 64 9 7 10 2-s2.0-0042508791 (Pubitemid 37040372)
-
(2003)
Journal of Clinical Psychiatry
, vol.64
, Issue.SUPPL. 9
, pp. 7-10
-
-
Wenk, G.L.1
-
57
-
-
0037490159
-
Ceramide stabilizes beta-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid beta-peptide biogenesis
-
DOI 10.1074/jbc.M300466200
-
Puglielli L., Ellis B. C., Saunders A. J., Kovacs D. M., Ceramide stabilizes β -site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid β -peptide biogenesis. Journal of Biological Chemistry 2003 278 22 19777 19783 2-s2.0-0037490159 10.1074/jbc.M300466200 (Pubitemid 36799164)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.22
, pp. 19777-19783
-
-
Puglielli, L.1
Ellis, B.C.2
Saunders, A.J.3
Kovacs, D.M.4
-
58
-
-
34248392684
-
Microglial activation and its implications in the brain diseases
-
DOI 10.2174/092986707780597961
-
Dheen S. T., Kaur C., Ling E.-A., Microglial activation and its implications in the brain diseases. Current Medicinal Chemistry 2007 14 11 1189 1197 2-s2.0-34248392684 10.2174/092986707780597961 (Pubitemid 46739320)
-
(2007)
Current Medicinal Chemistry
, vol.14
, Issue.11
, pp. 1189-1197
-
-
Dheen, S.T.1
Kaur, C.2
Ling, E.-A.3
-
59
-
-
74449093467
-
Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia
-
2-s2.0-74449093467 10.1016/j.neuroscience.2009.12.020
-
Nayak D., Huo Y., Kwang W. X. T., Pushparaj P. N., Kumar S. D., Ling E.-A., Dheen S. T., Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia. Neuroscience 2010 166 1 132 144 2-s2.0-74449093467 10.1016/j.neuroscience.2009.12.020
-
(2010)
Neuroscience
, vol.166
, Issue.1
, pp. 132-144
-
-
Nayak, D.1
Huo, Y.2
Kwang, W.X.T.3
Pushparaj, P.N.4
Kumar, S.D.5
Ling, E.-A.6
Dheen, S.T.7
-
60
-
-
79551552043
-
Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes A β generation
-
2-s2.0-79551552043 10.1523/JNEUROSCI.2954-10.2011
-
Tamboli I. Y., Hampel H., Tien N. T., Tolksdorf K., Breiden B., Mathews P. M., Saftig P., Sandhoff K., Walter J., Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes A β generation. Journal of Neuroscience 2011 31 5 1837 1849 2-s2.0-79551552043 10.1523/JNEUROSCI.2954-10.2011
-
(2011)
Journal of Neuroscience
, vol.31
, Issue.5
, pp. 1837-1849
-
-
Tamboli, I.Y.1
Hampel, H.2
Tien, N.T.3
Tolksdorf, K.4
Breiden, B.5
Mathews, P.M.6
Saftig, P.7
Sandhoff, K.8
Walter, J.9
-
61
-
-
38449102577
-
Lactosylceramide: A lipid second messenger in neuroinflammatory disease
-
supplement 1 2-s2.0-38449102577 10.1111/j.1471-4159.2007.04822.x
-
Won J.-S., Singh A. K., Singh I., Lactosylceramide: a lipid second messenger in neuroinflammatory disease. Journal of Neurochemistry 2007 103 supplement 1 180 191 2-s2.0-38449102577 10.1111/j.1471-4159.2007.04822.x
-
(2007)
Journal of Neurochemistry
, vol.103
, pp. 180-191
-
-
Won, J.-S.1
Singh, A.K.2
Singh, I.3
-
62
-
-
9144261868
-
NSAIDs increase survival in the Sandhoff disease mouse: Synergy with N-butyldeoxynojirimycin
-
DOI 10.1002/ana.20242
-
Jeyakumar M., Smith D. A., Williams I. M., Borja M. C., Neville D. C. A., Butters T. D., Dwek R. A., Platt F. M., NSAIDs increase survival in the Sandhoff disease mouse: synergy with N-butyldeoxynojirimycin. Annals of Neurology 2004 56 5 642 649 2-s2.0-9144261868 10.1002/ana.20242 (Pubitemid 39540744)
-
(2004)
Annals of Neurology
, vol.56
, Issue.5
, pp. 642-649
-
-
Jeyakumar, M.1
Smith, D.A.2
Williams, I.M.3
Borja, M.C.4
Neville, D.C.A.5
Butters, T.D.6
Dwek, R.A.7
Platt, F.M.8
-
63
-
-
0037378110
-
Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis
-
DOI 10.1093/brain/awg089
-
Jeyakumar M., Thomas R., Elliot-Smith E., Smith D. A., van der Spoel A. C., D'Azzo A., Perry V. H., Butters T. D., Dwek R. A., Platt F. M., Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis. Brain 2003 126 4 974 987 2-s2.0-0037378110 10.1093/brain/awg089 (Pubitemid 36372994)
-
(2003)
Brain
, vol.126
, Issue.4
, pp. 974-987
-
-
Jeyakumar, M.1
Thomas, R.2
Elliot-Smith, E.3
Smith, D.A.4
Van Der Spoel, A.C.5
Dazzo, A.6
Perry, V.H.7
Butters, T.D.8
Dwek, R.A.9
Platt, F.M.10
-
64
-
-
34548349220
-
Developmental analysis of CNS pathology in the lysosomal storage disease alpha-mannosidosis
-
DOI 10.1097/nen.0b013e31812503b6, PII 0000507220070800000003
-
Crawley A. C., Walkley S. U., Developmental analysis of CNS pathology in the lysosomal storage disease α -mannosidosis. Journal of Neuropathology and Experimental Neurology 2007 66 8 687 697 2-s2.0-34548349220 10.1097/nen.0b013e31812503b6 (Pubitemid 47344248)
-
(2007)
Journal of Neuropathology and Experimental Neurology
, vol.66
, Issue.8
, pp. 687-697
-
-
Crawley, A.C.1
Walkley, S.U.2
-
65
-
-
34548261716
-
Glycolipid and ganglioside metabolism imbalances in Huntington's disease
-
DOI 10.1016/j.nbd.2007.05.003, PII S0969996107001076
-
Desplats P. A., Denny C. A., Kass K. E., Gilmartin T., Head S. R., Sutcliffe J. G., Seyfried T. N., Thomas E. A., Glycolipid and ganglioside metabolism imbalances in Huntington's disease. Neurobiology of Disease 2007 27 3 265 277 2-s2.0-34548261716 10.1016/j.nbd.2007.05.003 (Pubitemid 47333188)
-
(2007)
Neurobiology of Disease
, vol.27
, Issue.3
, pp. 265-277
-
-
Desplats, P.A.1
Denny, C.A.2
Kass, K.E.3
Gilmartin, T.4
Head, S.R.5
Sutcliffe, J.G.6
Seyfried, T.N.7
Thomas, E.A.8
-
66
-
-
78651326446
-
Cerebellar lipid differences between R6/1 transgenic mice and humans with Huntington's disease
-
2-s2.0-78651326446 10.1111/j.1471-4159.2010.06964.x
-
Denny C. A., Desplats P. A., Thomas E. A., Seyfried T. N., Cerebellar lipid differences between R6/1 transgenic mice and humans with Huntington's disease. Journal of Neurochemistry 2010 115 3 748 758 2-s2.0-78651326446 10.1111/j.1471-4159.2010.06964.x
-
(2010)
Journal of Neurochemistry
, vol.115
, Issue.3
, pp. 748-758
-
-
Denny, C.A.1
Desplats, P.A.2
Thomas, E.A.3
Seyfried, T.N.4
-
67
-
-
33745543727
-
Neurotrophic enhancers as therapy for behavioral deficits in rodent models of Huntington's disease: Use of gangliosides, substituted pyrimidines, and mesenchymal stem cells
-
DOI 10.1177/1534582306289367
-
Dunbar G. L., Sandstrom M. I., Rossignol J., Lescaudron L., Neurotrophic enhancers as therapy for behavioral deficits in rodent models of Huntington's disease: use of gangliosides, substituted pyrimidines, and mesenchymal stem cells. Behavioral and Cognitive Neuroscience Reviews 2006 5 2 63 79 2-s2.0-33745543727 10.1177/1534582306289367 (Pubitemid 43979193)
-
(2006)
Behavioral and Cognitive Neuroscience Reviews
, vol.5
, Issue.2
, pp. 63-79
-
-
Dunbar, G.L.1
Sandstrom, M.I.2
Rossignol, J.3
Lescaudron, L.4
-
68
-
-
77949735761
-
Impaired ganglioside metabolism in Huntington's disease and neuroprotective role of GM1
-
2-s2.0-77949735761 10.1523/JNEUROSCI.6348-09.2010
-
Maglione V., Marchi P., Di Pardo A., Lingrell S., Horkey M., Tidmarsh E., Sipione S., Impaired ganglioside metabolism in Huntington's disease and neuroprotective role of GM1. Journal of Neuroscience 2010 30 11 4072 4080 2-s2.0-77949735761 10.1523/JNEUROSCI.6348-09.2010
-
(2010)
Journal of Neuroscience
, vol.30
, Issue.11
, pp. 4072-4080
-
-
Maglione, V.1
Marchi, P.2
Di Pardo, A.3
Lingrell, S.4
Horkey, M.5
Tidmarsh, E.6
Sipione, S.7
-
69
-
-
84857744138
-
Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice
-
2-s2.0-84857744138 10.1073/pnas.1114502109
-
Di Pardo A., Maglione V., Alpaugh M., Horkey M., Atwal R. S., Sassone J., Ciammola A., Steffan J. S., Fouad K., Truant R., Sipione S., Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice. Proceedings of the National Academy of Sciences of the United States of America 2012 109 9 3528 3533 2-s2.0-84857744138 10.1073/pnas.1114502109
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, Issue.9
, pp. 3528-3533
-
-
Di Pardo, A.1
Maglione, V.2
Alpaugh, M.3
Horkey, M.4
Atwal, R.S.5
Sassone, J.6
Ciammola, A.7
Steffan, J.S.8
Fouad, K.9
Truant, R.10
Sipione, S.11
-
70
-
-
77953293446
-
Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation
-
2-s2.0-77953293446 10.1016/j.biochi.2010.02.008
-
Snider A. J., Orr Gandy K. A., Obeid L. M., Sphingosine kinase: role in regulation of bioactive sphingolipid mediators in inflammation. Biochimie 2010 92 6 707 715 2-s2.0-77953293446 10.1016/j.biochi.2010.02.008
-
(2010)
Biochimie
, vol.92
, Issue.6
, pp. 707-715
-
-
Snider, A.J.1
Orr Gandy, K.A.2
Obeid, L.M.3
-
71
-
-
11144354259
-
PAF-mediated pulmonary edema: A new role for acid sphingomyelinase and ceramide
-
DOI 10.1038/nm977
-
Göggell R., Winoto-Morbach S., Vielhaber G., Imai Y., Lindner K., Brade L., Brade H., Ehlers S., Slutsky A. S., Schütze S., Gulbins E., Uhlig S., PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide. Nature Medicine 2004 10 2 155 160 2-s2.0-11144354259 10.1038/nm977 (Pubitemid 38524885)
-
(2004)
Nature Medicine
, vol.10
, Issue.2
, pp. 155-160
-
-
Goggell, R.1
Winoto-Morbach, S.2
Vielhaber, G.3
Imai, Y.4
Lindner, K.5
Brade, L.6
Brade, H.7
Ehlers, S.8
Slutsky, A.S.9
Schutze, S.10
Gulbins, E.11
Uhlig, S.12
-
72
-
-
38749119748
-
Ceramide: A key signaling molecule in a guinea pig model of allergic asthmatic response and airway inflammation
-
DOI 10.1124/jpet.107.131565
-
Masini E., Giannini L., Nistri S., Cinci L., Mastroianni R., Xu W., Comhair S. A. A., Li D., Cuzzocrea S., Matuschak G. M., Salvemini D., Ceramide: a key signaling molecule in a guinea pig model of allergic asthmatic response and airway inflammation. Journal of Pharmacology and Experimental Therapeutics 2008 324 2 548 557 2-s2.0-38749119748 10.1124/jpet.107.131565 (Pubitemid 351185855)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.324
, Issue.2
, pp. 548-557
-
-
Masini, E.1
Giannini, L.2
Nistri, S.3
Cinci, L.4
Mastroianni, R.5
Xu, W.6
Comhair, S.A.A.7
Li, D.8
Cuzzocrea, S.9
Matuschak, G.M.10
Salvemini, D.11
-
73
-
-
34547659848
-
Acid sphingomyelinase inhibition suppresses lipopolysaccharide-mediated release of inflammatory cytokines from macrophages and protects against disease pathology in dextran sulphate sodium-induced colitis in mice
-
DOI 10.1111/j.1365-2567.2007.02612.x
-
Sakata A., Ochiai T., Shimeno H., Hikishima S., Yokomatsu T., Shibuya S., Toda A., Eyanagi R., Soeda S., Acid sphingomyelinase inhibition suppresses lipopolysaccharide-mediated release of inflammatory cytokines from macrophages and protects against disease pathology in dextran sulphate sodium-induced colitis in mice. Immunology 2007 122 1 54 64 2-s2.0-34547659848 10.1111/j.1365-2567.2007.02612.x (Pubitemid 47222595)
-
(2007)
Immunology
, vol.122
, Issue.1
, pp. 54-64
-
-
Sakata, A.1
Ochiai, T.2
Shimeno, H.3
Hikishima, S.4
Yokomatsu, T.5
Shibuya, S.6
Toda, A.7
Eyanagi, R.8
Soeda, S.9
-
74
-
-
84876921937
-
Anti-inflammatory mechanism of exogenous C2 ceramide in lipopolysaccharide-stimulated microglia
-
10.1016/j.bbalip.2013.01.020
-
Jung J. S., Shin K. O., Lee Y. M., Anti-inflammatory mechanism of exogenous C2 ceramide in lipopolysaccharide-stimulated microglia. Biochimica et Biophysica Acta 2013 1831 6 1016 1026 10.1016/j.bbalip.2013.01.020
-
(2013)
Biochimica et Biophysica Acta
, vol.1831
, Issue.6
, pp. 1016-1026
-
-
Jung, J.S.1
Shin, K.O.2
Lee, Y.M.3
-
75
-
-
41849092177
-
Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis
-
DOI 10.1038/nm1748, PII NM1748
-
Teichgräber V., Ulrich M., Endlich N., Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. Nature Medicine 2008 14 4 382 391 (Pubitemid 351499396)
-
(2008)
Nature Medicine
, vol.14
, Issue.4
, pp. 382-391
-
-
Teichgraber, V.1
Ulrich, M.2
Endlich, N.3
Riethmuller, J.4
Wilker, B.5
De Oliveira-Munding, C.C.6
Van Heeckeren, A.M.7
Barr, M.L.8
Von Kurthy, G.9
Schmid, K.W.10
Weller, M.11
Tummler, B.12
Lang, F.13
Grassme, H.14
Doring, G.15
Gulbins, E.16
-
76
-
-
77953461364
-
The role of sphingolipids and ceramide in pulmonary inflammation in cystic fibrosis
-
2-s2.0-77953461364 10.2174/1874306401004020039
-
Becker K. A., Riethmüller J., Zhang Y., Gulbins E., The role of sphingolipids and ceramide in pulmonary inflammation in cystic fibrosis. Open Respiratory Medicine Journal 2010 4 39 47 2-s2.0-77953461364 10.2174/1874306401004020039
-
(2010)
Open Respiratory Medicine Journal
, vol.4
, pp. 39-47
-
-
Becker, K.A.1
Riethmüller, J.2
Zhang, Y.3
Gulbins, E.4
-
77
-
-
45949095358
-
Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide
-
DOI 10.1189/jlb.0108076
-
Sun Y., Fox T., Adhikary G., Kester M., Pearlman E., Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide. Journal of Leukocyte Biology 2008 83 6 1512 1521 2-s2.0-45949095358 10.1189/jlb.0108076 (Pubitemid 351960333)
-
(2008)
Journal of Leukocyte Biology
, vol.83
, Issue.6
, pp. 1512-1521
-
-
Sun, Y.1
Fox, T.2
Adhikary, G.3
Kester, M.4
Pearlman, E.5
-
78
-
-
78650645373
-
Ceramide and ceramide 1-phosphate are negative regulators of TNF- α production induced by lipopolysaccharide
-
2-s2.0-78650645373 10.4049/jimmunol.0902926
-
Józefowski S., Czerkies M., Łukasik A., Bielawska A., Bielawski J., Kwiatkowska K., Sobota A., Ceramide and ceramide 1-phosphate are negative regulators of TNF- α production induced by lipopolysaccharide. Journal of Immunology 2010 185 11 6960 6973 2-s2.0-78650645373 10.4049/jimmunol.0902926
-
(2010)
Journal of Immunology
, vol.185
, Issue.11
, pp. 6960-6973
-
-
Józefowski, S.1
Czerkies, M.2
Łukasik, A.3
Bielawska, A.4
Bielawski, J.5
Kwiatkowska, K.6
Sobota, A.7
-
79
-
-
77954232042
-
Studies on the role of acid sphingomyelinase and ceramide in the regulation of tumor necrosis factor α (TNF α)-converting enzyme activity and TNF α secretion in macrophages
-
2-s2.0-77954232042 10.1074/jbc.M109.080671
-
Rozenova K. A., Deevska G. M., Karakashian A. A., Nikolova-Karakashian M. N., Studies on the role of acid sphingomyelinase and ceramide in the regulation of tumor necrosis factor α (TNF α)-converting enzyme activity and TNF α secretion in macrophages. Journal of Biological Chemistry 2010 285 27 21103 21113 2-s2.0-77954232042 10.1074/jbc.M109.080671
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.27
, pp. 21103-21113
-
-
Rozenova, K.A.1
Deevska, G.M.2
Karakashian, A.A.3
Nikolova-Karakashian, M.N.4
-
80
-
-
0035340952
-
Ceramide inhibits lipopolysaccharide-mediated nitric oxide synthase and cyclooxygenase-2 induction in macrophages: Effects on protein kinases and transcription factors
-
Hsu Y.-W., Chi K.-H., Huang W.-C., Lin W.-W., Ceramide inhibits lipopolysaccharide-mediated nitric oxide synthase and cyclooxygenase-2 induction in macrophages: effects on protein kinases and transcription factors. Journal of Immunology 2001 166 9 5388 5397 2-s2.0-0035340952 (Pubitemid 32374158)
-
(2001)
Journal of Immunology
, vol.166
, Issue.9
, pp. 5388-5397
-
-
Hsu, Y.-W.1
Chi, K.-H.2
Huang, W.-C.3
Lin, W.-W.4
-
81
-
-
0344406769
-
Potentiation of lipopolysaccharide-inducible cyclooxygenase 2 expression by C2-ceramide via c-Jun N-terminal kinase-mediated activation of CCAAT/enhancer binding protein beta in macrophages
-
DOI 10.1124/mol.63.3.512
-
Cho Y. H., Lee C. H., Kim S. G., Potentiation of lipopolysaccharide- inducible cyclooxygenase 2 expression by C2-ceramide via c-Jun N-terminal kinase-mediated activation of CCAAT/enhancer binding protein β in macrophages. Molecular Pharmacology 2003 63 3 512 523 2-s2.0-0344406769 10.1124/mol.63.3.512 (Pubitemid 36297320)
-
(2003)
Molecular Pharmacology
, vol.63
, Issue.3
, pp. 512-523
-
-
Cho, Y.H.1
Lee, C.H.2
Kim, S.G.3
-
82
-
-
0030784482
-
Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation
-
DOI 10.1084/jem.186.11.1831
-
Haimovitz-Friedman A., Cordon-Cardo C., Bayoumy S., Garzotto M., McLoughlin M., Gallily R., Edwards C. K. III, Schuchman E. H., Fuks Z., Kolesnick R., Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation. Journal of Experimental Medicine 1997 186 11 1831 1841 2-s2.0-0030784482 10.1084/jem.186.11.1831 (Pubitemid 27524593)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.11
, pp. 1831-1841
-
-
Haimovitz-Friedman, A.1
Cordon-Cardo, C.2
Bayoumy, S.3
Garzotto, M.4
McLoughlin, M.5
Gallily, R.6
Edwards III, C.K.7
Schuchman, E.H.8
Fuks, Z.9
Kolesnick, R.10
-
83
-
-
0026458406
-
TNF activates NF- B by phosphatidylcholine-specific phospholipase C- induced "acidic" sphingomyelin breakdown
-
2-s2.0-0026458406 10.1016/0092-8674(92)90553-O
-
Schutze S., Potthoff K., Machleidt T., Berkovic D., Wiegmann K., Kronke M., TNF activates NF- B by phosphatidylcholine-specific phospholipase C- induced "acidic" sphingomyelin breakdown. Cell 1992 71 5 765 776 2-s2.0-0026458406 10.1016/0092-8674(92)90553-O
-
(1992)
Cell
, vol.71
, Issue.5
, pp. 765-776
-
-
Schutze, S.1
Potthoff, K.2
Machleidt, T.3
Berkovic, D.4
Wiegmann, K.5
Kronke, M.6
-
84
-
-
68349093905
-
Regulation of macrophage function by sphingosine-1-phosphate
-
2-s2.0-68349093905 10.1016/j.imbio.2009.06.003
-
Weigert A., Weis N., Brüne B., Regulation of macrophage function by sphingosine-1-phosphate. Immunobiology 2009 214 9-10 748 760 2-s2.0-68349093905 10.1016/j.imbio.2009.06.003
-
(2009)
Immunobiology
, vol.214
, Issue.9-10
, pp. 748-760
-
-
Weigert, A.1
Weis, N.2
Brüne, B.3
-
85
-
-
39649123726
-
Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages
-
2-s2.0-39649123726 10.1016/j.prostaglandins.2007.11.002
-
Hammad S. M., Crellin H. G., Wu B. X., Melton J., Anelli V., Obeid L. M., Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages. Prostaglandins and Other Lipid Mediators 2008 85 3-4 107 114 2-s2.0-39649123726 10.1016/j.prostaglandins.2007.11.002
-
(2008)
Prostaglandins and Other Lipid Mediators
, vol.85
, Issue.3-4
, pp. 107-114
-
-
Hammad, S.M.1
Crellin, H.G.2
Wu, B.X.3
Melton, J.4
Anelli, V.5
Obeid, L.M.6
-
86
-
-
0642338117
-
Sphingosine-1-phosphate signaling in endothelial activation
-
2-s2.0-0642338117
-
Ozaki H., Hla T., Lee M.-J., Sphingosine-1-phosphate signaling in endothelial activation. Journal of Atherosclerosis and Thrombosis 2003 10 3 125 131 2-s2.0-0642338117
-
(2003)
Journal of Atherosclerosis and Thrombosis
, vol.10
, Issue.3
, pp. 125-131
-
-
Ozaki, H.1
Hla, T.2
Lee, M.-J.3
-
87
-
-
21844457949
-
Sphingosine 1-phosphate and its receptors: An autocrine and paracrine network
-
DOI 10.1038/nri1650
-
Rosen H., Goetzl E. J., Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network. Nature Reviews Immunology 2005 5 7 560 570 2-s2.0-21844457949 10.1038/nri1650 (Pubitemid 40961333)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.7
, pp. 560-570
-
-
Rosen, H.1
Goetzl, E.J.2
-
88
-
-
0345376673
-
Microglial activation state and lysophospholipid acid receptor expression
-
DOI 10.1016/j.ijdevneu.2003.09.003
-
Tham C.-S., Lin F.-F., Rao T. S., Yu N., Webb M., Microglial activation state and lysophospholipid acid receptor expression. International Journal of Developmental Neuroscience 2003 21 8 431 443 2-s2.0-0345376673 10.1016/j.ijdevneu.2003.09.003 (Pubitemid 37491477)
-
(2003)
International Journal of Developmental Neuroscience
, vol.21
, Issue.8
, pp. 431-443
-
-
Tham, C.-S.1
Lin, F.-F.2
Rao, T.S.3
Yu, N.4
Webb, M.5
-
89
-
-
33645978074
-
Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors
-
2-s2.0-33645978074 10.1002/glia.20324
-
Bassi R., Anelli V., Giussani P., Tettamanti G., Viani P., Riboni L., Sphingosine-1-phosphate is released by cerebellar astrocytes in response to bFGF and induces astrocyte proliferation through Gi-protein-coupled receptors. GLIA 2006 53 6 621 630 2-s2.0-33645978074 10.1002/glia.20324
-
(2006)
GLIA
, vol.53
, Issue.6
, pp. 621-630
-
-
Bassi, R.1
Anelli, V.2
Giussani, P.3
Tettamanti, G.4
Viani, P.5
Riboni, L.6
-
90
-
-
38149117052
-
Sphingosine kinase signalling in immune cells: Potential as novel therapeutic targets
-
2-s2.0-38149117052 10.1016/j.bbapap.2007.07.013
-
Melendez A. J., Sphingosine kinase signalling in immune cells: potential as novel therapeutic targets. Biochimica et Biophysica Acta 2008 1784 1 66 75 2-s2.0-38149117052 10.1016/j.bbapap.2007.07.013
-
(2008)
Biochimica et Biophysica Acta
, vol.1784
, Issue.1
, pp. 66-75
-
-
Melendez, A.J.1
-
91
-
-
0037174916
-
JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells
-
DOI 10.1074/jbc.M203885200
-
Kim O. S., Park E. J., Joe E.-H., Jou I., JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells. Journal of Biological Chemistry 2002 277 43 40594 40601 2-s2.0-0037174916 10.1074/jbc.M203885200 (Pubitemid 35215639)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.43
, pp. 40594-40601
-
-
Kim, O.S.1
Park, E.J.2
Joe, E.-H.3
Jou, I.4
-
92
-
-
0035168530
-
Gangliosides GD1b, GT1b, and GQ1b enhance IL-2 and IFN-γ production and suppress IL-4 and IL-5 production in phytohemagglutinin-stimulated human T cells
-
Kanda N., Watanabe S., Gangliosides GD1b, GT1b, and GQ1b enhance IL-2 and IFN- γ production and suppress IL-4 and IL-5 production in phytohemagglutinin-stimulated human T cells. Journal of Immunology 2001 166 1 72 80 2-s2.0-0035168530 (Pubitemid 32038418)
-
(2001)
Journal of Immunology
, vol.166
, Issue.1
, pp. 72-80
-
-
Kanda, N.1
Watanabe, S.2
-
93
-
-
0036544646
-
Trisialoganglioside GT1b induces in vivo degeneration of nigral dopaminergic neurons: Role of microglia
-
2-s2.0-0036544646 10.1002/glia.10047
-
Ryu J. K., Shin W. H., Kim J., Joe E. H., Lee Y. B., Cho K. G., Oh Y. J., Kim S. U., Jin B. K., Trisialoganglioside GT1b induces in vivo degeneration of nigral dopaminergic neurons: role of microglia. GLIA 2002 38 1 15 23 2-s2.0-0036544646 10.1002/glia.10047
-
(2002)
GLIA
, vol.38
, Issue.1
, pp. 15-23
-
-
Ryu, J.K.1
Shin, W.H.2
Kim, J.3
Joe, E.H.4
Lee, Y.B.5
Cho, K.G.6
Oh, Y.J.7
Kim, S.U.8
Jin, B.K.9
-
94
-
-
0032548943
-
Structural transitions associated with the interaction of Alzheimer beta- amyloid peptides with gangliosides
-
DOI 10.1074/jbc.273.8.4506
-
McLaurin J., Franklin T., Fraser P. E., Chakrabartty A., Structural transitions associated with the interaction of Alzheimer β-amyloid peptides with gangliosides. Journal of Biological Chemistry 1998 273 8 4506 4515 2-s2.0-0032548943 10.1074/jbc.273.8.4506 (Pubitemid 28103191)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.8
, pp. 4506-4515
-
-
McLaurin, J.1
Franklin, T.2
Fraser, P.E.3
Chakrabartty, A.4
-
95
-
-
0036594989
-
Interleukin-13 and -4 induce death of activated microglia
-
2-s2.0-0036594989 10.1002/glia.10057
-
Yang M.-S., Park E. J., Sohn S., Kwon H. J., Shin W.-H., Pyo H. K., Jin B., Choi K. S., Jou I., Joe E.-H., Interleukin-13 and -4 induce death of activated microglia. GLIA 2002 38 4 273 280 2-s2.0-0036594989 10.1002/glia.10057
-
(2002)
GLIA
, vol.38
, Issue.4
, pp. 273-280
-
-
Yang, M.-S.1
Park, E.J.2
Sohn, S.3
Kwon, H.J.4
Shin, W.-H.5
Pyo, H.K.6
Jin, B.7
Choi, K.S.8
Jou, I.9
Joe, E.-H.10
|