-
1
-
-
0032936786
-
Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates
-
Sierra EE, Goldman ID: Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates. Semin Oncol. 1999 Apr, 26 (2 Suppl 6), 11-23. (Pubitemid 29218023)
-
(1999)
Seminars in Oncology
, vol.26
, Issue.2 SUPPL.
, pp. 11-23
-
-
Sierra, E.E.1
Goldman, I.D.2
-
2
-
-
77953293418
-
Genes involved with folate uptake and distribution and their association with colorectal cancer risk
-
Apr, Epub 2009 Dec 27
-
Figueiredo JC, Levine AJ, Lee WH, Conti DV, Poynter JN, Campbell PT, Duggan D, Lewinger JP, Martinez ME, Ulrich CM, Newcomb P, Potter J, Limburg PJ, Hopper J, Jenkins MA, Le Marchand L, Baron JA, Haile RW: Genes involved with folate uptake and distribution and their association with colorectal cancer risk. Cancer Causes Control. 2010 Apr, 21(4), 597-608. Epub 2009 Dec 27.
-
(2010)
Cancer Causes Control
, vol.21
, Issue.4
, pp. 597-608
-
-
Figueiredo, J.C.1
Levine, A.J.2
Lee, W.H.3
Conti, D.V.4
Poynter, J.N.5
Campbell, P.T.6
Duggan, D.7
Lewinger, J.P.8
Martinez, M.E.9
Ulrich, C.M.10
Newcomb, P.11
Potter, J.12
Limburg, P.J.13
Hopper, J.14
Jenkins, M.A.15
Le Marchand, L.16
Baron, J.A.17
Haile, R.W.18
-
3
-
-
84885459819
-
-
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd= ShowDetailView&TermToSearch=6573
-
-
-
-
4
-
-
10544249877
-
Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders
-
Leclerc D, Campeau E, Goyette P, Adjalla CE, Christensen B, Ross M, Eydoux P, Rosenblatt DS, Rozen R, Gravel RA: Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. Hum Mol Genet 1996 Dec, 5(12), 1867-1874. (Pubitemid 26413628)
-
(1996)
Human Molecular Genetics
, vol.5
, Issue.12
, pp. 1867-1874
-
-
Leclerc, D.1
Campeau, E.2
Goyette, P.3
Adjalla, C.E.4
Christensen, B.5
Ross, M.6
Eydoux, P.7
Rosenblatt, D.S.8
Rozen, R.9
Gravel, R.A.10
-
5
-
-
84885449814
-
-
http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/clinical-disease-id/ 216359
-
-
-
-
6
-
-
84885446517
-
-
http://www.drugs.com/sfs/methotrexate-side-effects.html
-
-
-
-
7
-
-
84885457461
-
-
http://indeks.mp.pl/desc.php?id=544
-
-
-
-
8
-
-
0033805360
-
A polymorphism (80G-〉A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia
-
Chango A, Emery-Fillon N, de Courcy GP, et al.: A polymorphism (80G-〉A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia. Mol Genet Metab 2000, 70, 310-315.
-
(2000)
Mol Genet Metab
, vol.70
, pp. 310-315
-
-
Chango, A.1
Emery-Fillon, N.2
De Courcy, G.P.3
-
9
-
-
0035187308
-
27 carriers
-
Whetstine JR, Gifford AJ, Witt T, et al.: Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers. Clin Cancer Res 2001, 7, 3416-3422. (Pubitemid 33069975)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.11
, pp. 3416-3422
-
-
Whetstine, J.R.1
Gifford, A.J.2
Witt, T.3
Liu, X.Y.4
Flatley, R.M.5
Norris, M.6
Haber, M.7
Taub, J.W.8
Ravindranath, Y.9
Matherly, L.H.10
-
10
-
-
0037110469
-
80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia
-
DOI 10.1182/blood.V100.10.3832
-
Laverdič C, Chiasson S, Costea I, Moghrabi A, Krajinovic M: Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia. Blood 2002 Nov 15, 100(10), 3832-3834. (Pubitemid 35303961)
-
(2002)
Blood
, vol.100
, Issue.10
, pp. 3832-3834
-
-
Laverdiere, C.1
Chiasson, S.2
Costea, I.3
Moghrabi, A.4
Krajinovic, M.5
-
11
-
-
33846682988
-
Genetic polymorphisms associated with adverse events and elimination of methotrexate in childhood acute lymphoblastic leukemia and malignant lymphoma
-
Epub 2006 Dec 19
-
Imanishi H, Okamura N, Yagi M, Noro Y, Moriya Y, Nakamura T, Hayakawa A, Takeshima Y, Sakaeda T, Matsuo M, Okumura K: Genetic polymorphisms associated with adverse events and elimination of methotrexate in childhood acute lymphoblastic leukemia and malignant lymphoma. J Hum Genet. 2007 52 (2), 166-171. Epub 2006 Dec 19.
-
(2007)
J Hum Genet
, vol.52
, Issue.2
, pp. 166-171
-
-
Imanishi, H.1
Okamura, N.2
Yagi, M.3
Noro, Y.4
Moriya, Y.5
Nakamura, T.6
Hayakawa, A.7
Takeshima, Y.8
Sakaeda, T.9
Matsuo, M.10
Okumura, K.11
-
12
-
-
33644625067
-
Effects of methylenetetrahydrofolate reductase and reduced folate carrier 1 polymorphisms on high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia or lymphoma
-
Feb
-
Shimasaki N, Mori T, Samejima H, Sato R, Shimada H, Yahagi N, Torii C, Yoshihara H, Tanigawara Y, Takahashi T, Kosaki K: Effects of methylenetetrahydrofolate reductase and reduced folate carrier 1 polymorphisms on high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia or lymphoma. J Pediatr Hematol Oncol 2006 Feb, 28(2), 64-68.
-
(2006)
J Pediatr Hematol Oncol
, vol.28
, Issue.2
, pp. 64-68
-
-
Shimasaki, N.1
Mori, T.2
Samejima, H.3
Sato, R.4
Shimada, H.5
Yahagi, N.6
Torii, C.7
Yoshihara, H.8
Tanigawara, Y.9
Takahashi, T.10
Kosaki, K.11
-
13
-
-
33846879411
-
Prognostic role of the reduced folate carrier, the major membrane transporter for methotrexate, in childhood acute lymphoblastic leukemia: A report from the children's oncology group
-
DOI 10.1158/1078-0432.CCR-06-2145
-
Ge Y, Haska CL, LaFiura K, Devidas M, Linda SB, Liu M, Thomas R, Taub JW, Matherly LH: Prognostic role of the reduced folate carrier, the major membrane transporter for methotrexate, in childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. Clin Cancer Res 2007 Jan 15, 13 (2 Pt 1), 451-457. (Pubitemid 46225349)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.2 I
, pp. 451-457
-
-
Ge, Y.1
Haska, C.L.2
LaFiura, K.3
Devidas, M.4
Linda, S.B.5
Liu, M.6
Thomas, R.7
Taub, J.W.8
Matherly, L.H.9
-
14
-
-
24744443273
-
G80A reduced folate carrier SNP modulates cellular uptake of folate and affords protection against thrombosis via a non homocysteine related mechanism
-
DOI 10.1016/j.lfs.2005.02.029, PII S0024320505005333
-
Yates Z, Lucock M: G80A reduced folate carrier SNP modulates cellular uptake of folate and affords protection against thrombosis via a non homocysteine related mechanism. Life Sci 2005, 77, 2735-2742. (Pubitemid 41297860)
-
(2005)
Life Sciences
, vol.77
, Issue.22
, pp. 2735-2742
-
-
Yates, Z.1
Lucock, M.2
-
15
-
-
0034072130
-
DNA methylation and cancer
-
DOI 10.1002/(SICI)1097-4652(200005)183:2<145::AID
-
Momparler RL, Bovenzi V: DNA methylation and cancer. Cell Physiol 2000 May, 183(2), 145-154. (Pubitemid 30185933)
-
(2000)
Journal of Cellular Physiology
, vol.183
, Issue.2
, pp. 145-154
-
-
Momparler, R.L.1
Bovenzi, V.2
-
16
-
-
30344462708
-
Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes
-
DOI 10.1158/1055-9965.EPI-05-0515
-
Lightfoot TJ, Skibola CF, Willett EV, et al.: Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes. Cancer Epidemiol Biomarkers Prev 2005, 14, 2999-3003. (Pubitemid 43068838)
-
(2005)
Cancer Epidemiology Biomarkers and Prevention
, vol.14
, Issue.12
, pp. 2999-3003
-
-
Lightfoot, T.J.1
Skibola, C.F.2
Willett, E.V.3
Skibola, D.R.4
Allan, J.M.5
Coppede, F.6
Adamson, P.J.7
Morgan, G.J.8
Roman, E.9
Smith, M.T.10
-
17
-
-
4644243438
-
Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma
-
DOI 10.1182/blood-2004-02-0557
-
Skibola CF, Forrest MS, Coppede F, et al.: Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma. Blood 2004,104, 2155-2162. (Pubitemid 39297871)
-
(2004)
Blood
, vol.104
, Issue.7
, pp. 2155-2162
-
-
Skibola, C.F.1
Forrest, M.S.2
Coppede, F.3
Agana, L.4
Hubbard, A.5
Smith, M.T.6
Bracci, P.M.7
Holly, E.A.8
-
18
-
-
1842418757
-
Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy
-
DOI 10.1016/j.ymgme.2003.12.010, PII S1096719203002932
-
Relton CL, Wilding CS, Laffling AJ, et al.: Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy. Mol Genet Metab 2004, 81, 273-281. (Pubitemid 38429990)
-
(2004)
Molecular Genetics and Metabolism
, vol.81
, Issue.4
, pp. 273-281
-
-
Relton, C.L.1
Wilding, C.S.2
Laffling, A.J.3
Jonas, P.A.4
Burgess, T.5
Binks, K.6
Tawn, E.J.7
Burn, J.8
-
19
-
-
28644446615
-
Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer
-
DOI 10.1158/1055-9965.EPI-05-0261
-
Ulrich CM, Curtin K, Potter JD, Bigler J, Caan B, Slattery ML: Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer. Cancer Epidemiol Biomarkers Prev 2005, 14, 2509-2516. (Pubitemid 41752708)
-
(2005)
Cancer Epidemiology Biomarkers and Prevention
, vol.14
, Issue.11 I
, pp. 2509-2516
-
-
Ulrich, C.M.1
Curtin, K.2
Potter, J.D.3
Bigler, J.4
Caan, B.5
Slattery, M.L.6
-
20
-
-
22144446041
-
Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia
-
Jul 15, Epub 2005 Mar 29
-
de Jonge R, Hooijberg JH, van Zelst BD, Jansen G, van Zantwijk CH, Kaspers GJ, Peters GJ, Ravindranath Y, Pieters R, Lindemans J: Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia. Blood 2005 Jul 15,106(2), 717-720. Epub 2005 Mar 29.
-
(2005)
Blood
, vol.106
, Issue.2
, pp. 717-720
-
-
De Jonge, R.1
Hooijberg, J.H.2
Van Zelst, B.D.3
Jansen, G.4
Van Zantwijk, C.H.5
Kaspers, G.J.6
Peters, G.J.7
Ravindranath, Y.8
Pieters, R.9
Lindemans, J.10
-
21
-
-
64049110710
-
Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia
-
Mar 5, Epub 2008 Nov 19
-
de Jonge R, Tissing WJ, Hooijberg JH, Jansen G, Kaspers GJ, Lindemans J, Peters GJ, Pieters R.: Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia. Blood 2009 Mar 5,113(10), 2284-2289. Epub 2008 Nov 19.
-
(2009)
Blood
, vol.113
, Issue.10
, pp. 2284-2289
-
-
De Jonge, R.1
Tissing, W.J.2
Hooijberg, J.H.3
Jansen, G.4
Kaspers, G.J.5
Lindemans, J.6
Peters, G.J.7
Pieters, R.8
-
22
-
-
77954725578
-
The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy number
-
Jun 10, Epub 2010 Mar 24
-
Gregers J, Christensen IJ, Dalhoff K, Lausen B, Schroeder H, Rosthoej S, Carlsen N, Schmiegelow K, Peterson C: The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy number. Blood 2010 Jun 10, 115(23), 4671-4677. Epub 2010 Mar 24.
-
(2010)
Blood
, vol.115
, Issue.23
, pp. 4671-4677
-
-
Gregers, J.1
Christensen, I.J.2
Dalhoff, K.3
Lausen, B.4
Schroeder, H.5
Rosthoej, S.6
Carlsen, N.7
Schmiegelow, K.8
Peterson, C.9
-
23
-
-
0345291171
-
Reduced folate carrier expression in acute lymphoblastic leukemia: A mechanism for ploidy but not lineage differences in methotrexate accumulation
-
Belkov VM, Krynetski EY, Schuetz JD, Yanishevski Y, Masson E, Mathew S, Raimondi S, Pui CH, Relling MV, Evans WE: Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation. Blood 1999 Mar 1,93(5), 1643-1650. (Pubitemid 29102492)
-
(1999)
Blood
, vol.93
, Issue.5
, pp. 1643-1650
-
-
Belkov, V.M.1
Eugene, Y.2
Schuetz, J.D.3
Yanishevski, Y.4
Masson, E.5
Mathew, S.6
Raimondi, S.7
Ching-Hon, P.8
Relling, M.V.9
Evans, W.E.10
-
24
-
-
0031669954
-
Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: Relationship to immunophenotype and ploidy
-
Zhang L, Taub JW, Williamson M, Wong SC, Hukku B, Pullen J, Ravindranath Y, Matherly LH: Reduced folate carrier gene expression in childhood acute lymphoblastic leukemia: relationship to immunophenotype and ploidy. Clin Cancer Res 1998 Sep, 4(9), 2169-2177. (Pubitemid 28415664)
-
(1998)
Clinical Cancer Research
, vol.4
, Issue.9
, pp. 2169-2177
-
-
Zhang, L.1
Taub, J.W.2
Williamson, M.3
Wong, S.C.4
Hukku, B.5
Pullen, J.6
Ravindranath, Y.7
Matherly, L.H.8
-
25
-
-
58949100713
-
Additional genetic risk factor for death in children with acute lymphoblastic leukemia: A common polymorphism of the MTHFR gene
-
Mar
-
Pietrzyk JJ, Bik-Multanowski M, Balwierz W, Skoczen S, Wojcik D, Chybicka A, Sikorska-Fic B, Matysiak M, Szczepanski T, Sonta-Jakimczyk D, Ploszynska A, Balcerska A, Mycko K, Bodalski J, Krawczuk-Rybak M, Kowalczyk J, Koltan A, Sobol G, Derwich K, Kwinta P: Additional genetic risk factor for death in children with acute lymphoblastic leukemia: a common polymorphism of the MTHFR gene. Pediatr Blood Cancer 2009 Mar, 52(3), 364-368.
-
(2009)
Pediatr Blood Cancer
, vol.52
, Issue.3
, pp. 364-368
-
-
Pietrzyk, J.J.1
Bik-Multanowski, M.2
Balwierz, W.3
Skoczen, S.4
Wojcik, D.5
Chybicka, A.6
Sikorska-Fic, B.7
Matysiak, M.8
Szczepanski, T.9
Sonta-Jakimczyk, D.10
Ploszynska, A.11
Balcerska, A.12
Mycko, K.13
Bodalski, J.14
Krawczuk-Rybak, M.15
Kowalczyk, J.16
Koltan, A.17
Sobol, G.18
Derwich, K.19
Kwinta, P.20
more..
-
26
-
-
33746972784
-
Folate cycle gene variants and chemotherapy toxicity in pediatric patients with acute lymphoblastic leukemia
-
Aug, Epub 2006 Jul 25
-
Costea I, Moghrabi A, Laverdiere C, Graziani A, Krajinovic M: Folate cycle gene variants and chemotherapy toxicity in pediatric patients with acute lymphoblastic leukemia. Haematologica 2006 Aug, 91(8), 1113-1116. Epub 2006 Jul 25.
-
(2006)
Haematologica
, vol.91
, Issue.8
, pp. 1113-1116
-
-
Costea, I.1
Moghrabi, A.2
Laverdiere, C.3
Graziani, A.4
Krajinovic, M.5
-
27
-
-
51649094290
-
Polymorphisms in folate-related genes: Association with side effects of high-dose methotrexate in childhood acute lymphoblastic leukemia
-
Sep, Epub 2008 Mar 27
-
Huang L, Tissing WJ, de Jonge R, van Zelst BD, Pieters R: Polymorphisms in folate-related genes: association with side effects of high-dose methotrexate in childhood acute lymphoblastic leukemia. Leukemia 2008 Sep, 22(9), 1798-1800. Epub 2008 Mar 27.
-
(2008)
Leukemia
, vol.22
, Issue.9
, pp. 1798-1800
-
-
Huang, L.1
Tissing, W.J.2
De Jonge, R.3
Van Zelst, B.D.4
Pieters, R.5
-
28
-
-
2942608990
-
Common gene polymorphisms in the metabolic folate and methylation pathway and the risk of acute lymphoblastic leukemia and non-Hodgkin's lymphoma in adults
-
Gemmati D, Ongaro A, Scapoli GL, Delia Porta M, Tognazzo S, Serino ML, Di Bona E, Rodeghiero F, Gilli G, Reverberi R, Caruso A, Pasello M, Pellati A, De Mattei M: Common gene polymorphisms in the metabolic folate and methylation pathway and the risk of acute lymphoblastic leukemia and non-Hodgkin's lymphoma in adults. Cancer Epidemiol Biomarkers Prev 2004 May, 13(5), 787-794. (Pubitemid 38737868)
-
(2004)
Cancer Epidemiology Biomarkers and Prevention
, vol.13
, Issue.5
, pp. 787-794
-
-
Gemmati, D.1
Ongaro, A.2
Scapoli, G.L.3
Della, P.M.4
Tognazzo, S.5
Serino, M.L.6
Di, B.E.7
Rodeghiero, F.8
Gilli, G.9
Reverberi, R.10
Caruso, A.11
Pasello, M.12
Pellati, A.13
De Mattei, M.14
-
29
-
-
0033607241
-
Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults
-
DOI 10.1073/pnas.96.22.12810
-
Skibola CF, Smith MT, Kane E, Roman E, Rollinson S, Cartwright RA, Morgan G: Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. Proc Natl Acad Sei U S A 1999 Oct 26, 96 (22), 12810-12815. (Pubitemid 29513584)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.22
, pp. 12810-12815
-
-
Skibola, C.F.1
Smith, M.T.2
Kane, E.3
Roman, E.4
Rollinson, S.5
Cartwright, R.A.6
Morgan, G.7
-
30
-
-
0035874520
-
Association between polymorphisms of folate- and methionine-metabolizing enzymes and susceptibility to malignant lymphoma
-
May 15
-
Matsuo K, Suzuki R, Hamajima N, Ogura M, Kagami Y, Taji H, Kondoh E, Maeda S, Asakura S, Kaba S, Nakamura S, Seto M, Morishima Y, Tajima K: Association between polymorphisms of folate- and methionine-metabolizing enzymes and susceptibility to malignant lymphoma. Blood 2001 May 15, 97(10), 3205-3209.
-
(2001)
Blood
, vol.97
, Issue.10
, pp. 3205-3209
-
-
Matsuo, K.1
Suzuki, R.2
Hamajima, N.3
Ogura, M.4
Kagami, Y.5
Taji, H.6
Kondoh, E.7
Maeda, S.8
Asakura, S.9
Kaba, S.10
Nakamura, S.11
Seto, M.12
Morishima, Y.13
Tajima, K.14
-
31
-
-
77953954360
-
Effect of methylenetetrahydrofolate reductase polymorphism on toxicity and efficacy of methotrexate in patients with rheumatoid arthritis
-
Świerkot J, Slçzak R, Karpiński P, Pawłowska J, Noga L, Szechiński J, Wiland P: Effect of methylenetetrahydrofolate reductase polymorphism on toxicity and efficacy of methotrexate in patients with rheumatoid arthritis. Reumatologia 2010, 48, 2, 81-93.
-
(2010)
Reumatologia
, vol.48
, Issue.2
, pp. 81-93
-
-
Świerkot, J.1
Slçzak, R.2
Karpiński, P.3
Pawłowska, J.4
Noga, L.5
Szechiński, J.6
Wiland, P.7
|