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Volumn 14, Issue 11 I, 2005, Pages 2509-2516

Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); METHIONINE SYNTHASE; REDUCED FOLATE CARRIER; THYMIDYLATE SYNTHASE;

EID: 28644446615     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-05-0261     Document Type: Article
Times cited : (113)

References (68)
  • 2
    • 3142735689 scopus 로고    scopus 로고
    • Washington (DC): World Cancer Research Fund/American Institute for Cancer Research
    • World Cancer Research Fund. Diet, nutrition, and the prevention of cancer: a global perspective. Washington (DC): World Cancer Research Fund/American Institute for Cancer Research; 1997.
    • (1997) Diet, Nutrition, and the Prevention of Cancer: A Global Perspective
  • 3
    • 0036324027 scopus 로고    scopus 로고
    • Epidemiologic studies of folate and colorectal neoplasia: A review
    • Giovannucci E. Epidemiologic studies of folate and colorectal neoplasia: a review. J Nutr 2002;132:2350-5S.
    • (2002) J Nutr , vol.132
    • Giovannucci, E.1
  • 4
    • 0242464932 scopus 로고    scopus 로고
    • Relation of plasma folate and methylenetetrahydrofolate reductase C677T polymorphism to colorectal adenomas
    • Marugame T, Tsuji E, Kiyohara C, et al. Relation of plasma folate and methylenetetrahydrofolate reductase C677T polymorphism to colorectal adenomas [comment]. Int J Epidemiol 2003;32:64-6.
    • (2003) Int J Epidemiol , vol.32 , pp. 64-66
    • Marugame, T.1    Tsuji, E.2    Kiyohara, C.3
  • 5
    • 0038523843 scopus 로고    scopus 로고
    • Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: A case control study
    • Pufulete M, Al-Ghnaniem R, Leather AJ, et al. Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study. Gastroenterology 2003;124:1240-8.
    • (2003) Gastroenterology , vol.124 , pp. 1240-1248
    • Pufulete, M.1    Al-Ghnaniem, R.2    Leather, A.J.3
  • 6
    • 0030615085 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer
    • Ma J, Stampfer MJ, Giovannucci E, et al. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res 1997;57:1098-102.
    • (1997) Cancer Res , vol.57 , pp. 1098-1102
    • Ma, J.1    Stampfer, M.J.2    Giovannucci, E.3
  • 7
    • 0032434823 scopus 로고    scopus 로고
    • A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma
    • Chen J, Giovannucci E, Hankinson SE, et al. A prospective study of methylenetetrahydrofolate reductase and methionine synthase gene polymorphisms, and risk of colorectal adenoma. Carcinogenesis 1998;19:2129-32.
    • (1998) Carcinogenesis , vol.19 , pp. 2129-2132
    • Chen, J.1    Giovannucci, E.2    Hankinson, S.E.3
  • 9
    • 0033370552 scopus 로고    scopus 로고
    • Colorectal adenomas and the C677T MTHFR polymorphism: Evidence for gene-environment interaction?
    • Ulrich CM, Kampman E, Bigler J, et al. Colorectal adenomas and the C677T MTHFR polymorphism: evidence for gene-environment interaction? Cancer Epidemiol Biomarkers Prev 1999;8:659-68.
    • (1999) Cancer Epidemiol Biomarkers Prev , vol.8 , pp. 659-668
    • Ulrich, C.M.1    Kampman, E.2    Bigler, J.3
  • 10
    • 0037096858 scopus 로고    scopus 로고
    • Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas
    • Ulrich CM, Bigler J, Bostick R, Fosdick L, Potter JD. Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas. Cancer Res 2002;62:3361-4.
    • (2002) Cancer Res , vol.62 , pp. 3361-3364
    • Ulrich, C.M.1    Bigler, J.2    Bostick, R.3    Fosdick, L.4    Potter, J.D.5
  • 11
    • 0033970043 scopus 로고    scopus 로고
    • Folate and carcinogenesis: An integrated scheme
    • Choi SW, Mason JB. Folate and carcinogenesis: an integrated scheme. J Nutr 2000;130:129-32.
    • (2000) J Nutr , vol.130 , pp. 129-132
    • Choi, S.W.1    Mason, J.B.2
  • 12
    • 0032713838 scopus 로고    scopus 로고
    • Folic acid deficiency and cancer: Mechanisms of DNA instability
    • Duthie SJ. Folic acid deficiency and cancer: mechanisms of DNA instability. Br Med Bull 1999;55:578-92.
    • (1999) Br Med Bull , vol.55 , pp. 578-592
    • Duthie, S.J.1
  • 14
    • 0029122937 scopus 로고
    • Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase
    • Horie N, Aiba H, Oguro K, Hojo H, Takeishi K. Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase. Cell Struct Funct 1995;20:191-7.
    • (1995) Cell Struct Funct , vol.20 , pp. 191-197
    • Horie, N.1    Aiba, H.2    Oguro, K.3    Hojo, H.4    Takeishi, K.5
  • 15
    • 0034518362 scopus 로고    scopus 로고
    • Searching expressed sequence tag databases: Discovery and confirmation of a common polymorphism in the thymidylate synthase gene
    • Ulrich C, Bigler J, Velicer C, Greene E, Farin F, Potter J. Searching expressed sequence tag databases: discovery and confirmation of a common polymorphism in the thymidylate synthase gene. Cancer Epidemiol Biomarkers Prev 2000;9:1381-5.
    • (2000) Cancer Epidemiol Biomarkers Prev , vol.9 , pp. 1381-1385
    • Ulrich, C.1    Bigler, J.2    Velicer, C.3    Greene, E.4    Farin, F.5    Potter, J.6
  • 16
    • 2442480694 scopus 로고    scopus 로고
    • A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intrarumoral TS mRNA levels
    • Mandola MV, Stoehlmacher J, Zhang W, et al. A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intrarumoral TS mRNA levels. Pharmacogenetics 2004;14:319-27.
    • (2004) Pharmacogenetics , vol.14 , pp. 319-327
    • Mandola, M.V.1    Stoehlmacher, J.2    Zhang, W.3
  • 17
    • 0033805360 scopus 로고    scopus 로고
    • A polymorphism (80G→A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia
    • Chango A, Emery-Fillon N, de Courcy GP, et al. A polymorphism (80G→A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia. Mol Genet Metab 2000;70:310-5.
    • (2000) Mol Genet Metab , vol.70 , pp. 310-315
    • Chango, A.1    Emery-Fillon, N.2    De Courcy, G.P.3
  • 18
    • 0037110469 scopus 로고    scopus 로고
    • Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia
    • Laverdiere C, Chiasson S, Costea I, Moghrabi A, Krajinovic M. Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia. Blood 2002;100:3832-4.
    • (2002) Blood , vol.100 , pp. 3832-3834
    • Laverdiere, C.1    Chiasson, S.2    Costea, I.3    Moghrabi, A.4    Krajinovic, M.5
  • 19
    • 13144282730 scopus 로고    scopus 로고
    • Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria
    • Leclerc D, Wilson A, Dumas R, et al. Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria. Proc Natl Acad Sci U S A 1998;95:3059-64.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3059-3064
    • Leclerc, D.1    Wilson, A.2    Dumas, R.3
  • 20
    • 0035864635 scopus 로고    scopus 로고
    • Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction
    • Chen J, Stampfer MJ, Ma J, et al. Influence of a methionine synthase (D919G) polymorphism on plasma homocysteine and folate levels and relation to risk of myocardial infarction. Atherosclerosis 2001;154:667-72.
    • (2001) Atherosclerosis , vol.154 , pp. 667-672
    • Chen, J.1    Stampfer, M.J.2    Ma, J.3
  • 21
    • 0032713815 scopus 로고    scopus 로고
    • Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations
    • Harmon D, Shields D, Woodside J, et al. Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations. Genet Epidemiol 1999;17:298-309.
    • (1999) Genet Epidemiol , vol.17 , pp. 298-309
    • Harmon, D.1    Shields, D.2    Woodside, J.3
  • 22
    • 0032878590 scopus 로고    scopus 로고
    • A polymorphism of the methionine synthase gene: Association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk
    • Ma J, Stampfer MJ, Christensen B, et al. A polymorphism of the methionine synthase gene: association with plasma folate, vitamin B12, homocyst(e)ine, and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 1999;8:825-9.
    • (1999) Cancer Epidemiol Biomarkers Prev , vol.8 , pp. 825-829
    • Ma, J.1    Stampfer, M.J.2    Christensen, B.3
  • 23
    • 0030804226 scopus 로고    scopus 로고
    • Sequence analysis of the coding region of human methionine synthase: Relevance to hyperhomocysteinaemia in neural-tube defects and vascular disease
    • van der Put NM, van der Molen EF, Kluijtmans LA, et al. Sequence analysis of the coding region of human methionine synthase: relevance to hyperhomocysteinaemia in neural-tube defects and vascular disease. QJM 1997;90:511-7.
    • (1997) QJM , vol.90 , pp. 511-517
    • Van Der Put, N.M.1    Van Der Molen, E.F.2    Kluijtmans, L.A.3
  • 24
    • 0037212592 scopus 로고    scopus 로고
    • Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study
    • Jacques PF, Bostom AG, Selhub J, et al. Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study. Atherosclerosis 2003;166:49-55.
    • (2003) Atherosclerosis , vol.166 , pp. 49-55
    • Jacques, P.F.1    Bostom, A.G.2    Selhub, J.3
  • 25
    • 11144236628 scopus 로고    scopus 로고
    • Colorectal cancer and the methylenetetrahydrofolate reductase 677C → T and methionine synthase 2756A → G polymorphisms: A study of 2,168 case-control pairs from the JANUS Cohort
    • Ulvik A, Vollset SE, Hansen S, Gislefoss R, Jellum E, Ueland PM. Colorectal cancer and the methylenetetrahydrofolate reductase 677C → T and methionine synthase 2756A → G polymorphisms: a study of 2,168 case-control pairs from the JANUS Cohort. Cancer Epidemiol Biomarkers Prev 2004;13:2175-80.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 2175-2180
    • Ulvik, A.1    Vollset, S.E.2    Hansen, S.3    Gislefoss, R.4    Jellum, E.5    Ueland, P.M.6
  • 26
    • 1642568671 scopus 로고    scopus 로고
    • Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk
    • Goode EL, Potter JD, Bigler J, Ulrich CM. Methionine synthase D919G polymorphism, folate metabolism, and colorectal adenoma risk. Cancer Epidemiol Biomarkers Prev 2004;13:157-62.
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 157-162
    • Goode, E.L.1    Potter, J.D.2    Bigler, J.3    Ulrich, C.M.4
  • 30
    • 0028102891 scopus 로고
    • Objective system for interviewer performance evaluation for use in epidemiologic studies
    • Edwards S, Slattery ML, Mori M, et al. Objective system for interviewer performance evaluation for use in epidemiologic studies. Am J Epidemiol 1994;140:1020-8.
    • (1994) Am J Epidemiol , vol.140 , pp. 1020-1028
    • Edwards, S.1    Slattery, M.L.2    Mori, M.3
  • 31
    • 0342886048 scopus 로고
    • A study of the reliability and comparative validity of the cardia dietary history
    • Liu K, Slattery M, Jacobs D, Jr., et al. A study of the reliability and comparative validity of the cardia dietary history. Ethn Dis 1994;4:15-27.
    • (1994) Ethn Dis , vol.4 , pp. 15-27
    • Liu, K.1    Slattery, M.2    Jacobs Jr., D.3
  • 32
    • 0033024334 scopus 로고    scopus 로고
    • Meat consumption, genetic susceptibility, and colon cancer risk: A United States multicenter case-control study
    • Kampman E, Slattery ML, Bigler J, et al. Meat consumption, genetic susceptibility, and colon cancer risk: a United States multicenter case-control study. Cancer Epidemiol Biomarkers Prev 1999;8:15-24.
    • (1999) Cancer Epidemiol Biomarkers Prev , vol.8 , pp. 15-24
    • Kampman, E.1    Slattery, M.L.2    Bigler, J.3
  • 33
    • 0029130796 scopus 로고
    • Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
    • Excoffier L, Slatkin M. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 1995;12:921-7.
    • (1995) Mol Biol Evol , vol.12 , pp. 921-927
    • Excoffier, L.1    Slatkin, M.2
  • 34
    • 0043175289 scopus 로고    scopus 로고
    • Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study
    • Stram DO, Haiman CA, Hirschhorn JN, et al. Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study. Hum Hered 2003;55:27-36.
    • (2003) Hum Hered , vol.55 , pp. 27-36
    • Stram, D.O.1    Haiman, C.A.2    Hirschhorn, J.N.3
  • 35
    • 0026702157 scopus 로고
    • Confidence interval estimation of interaction
    • Hosmer DW, Lemeshow S. Confidence interval estimation of interaction. Epidemiology 1992;3:452-6.
    • (1992) Epidemiology , vol.3 , pp. 452-456
    • Hosmer, D.W.1    Lemeshow, S.2
  • 36
    • 0036265638 scopus 로고    scopus 로고
    • Pharmacogenetics and folate metabolism - A promising direction
    • Ulrich CM, Robien K, Sparks R. Pharmacogenetics and folate metabolism - a promising direction. Pharmacogenomics 2002;3:299-313.
    • (2002) Pharmacogenomics , vol.3 , pp. 299-313
    • Ulrich, C.M.1    Robien, K.2    Sparks, R.3
  • 37
    • 0037156953 scopus 로고    scopus 로고
    • Thymidylate synthase polymorphism and survival of colorectal cancer patients treated with 5-fluorouracil
    • Ulrich CM, Potter JD. Thymidylate synthase polymorphism and survival of colorectal cancer patients treated with 5-fluorouracil [comment]. Br J Cancer 2002;86:22.
    • (2002) Br J Cancer , vol.86 , pp. 22
    • Ulrich, C.M.1    Potter, J.D.2
  • 38
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase [letter]. Nat Gen 1995;10:111-3.
    • (1995) Nat Gen , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 39
    • 0032573077 scopus 로고    scopus 로고
    • A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells
    • Bagley PJ, Selhub J. A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells. Proc Natl Acad Sci U S A 1998;95:13217-20.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 13217-13220
    • Bagley, P.J.1    Selhub, J.2
  • 40
    • 0035750549 scopus 로고    scopus 로고
    • Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy
    • Pullarkat ST, Stoehlmacher J, Ghaderi V, et al. Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy. Pharmacogenomics J 2001;1:65-70.
    • (2001) Pharmacogenomics J , vol.1 , pp. 65-70
    • Pullarkat, S.T.1    Stoehlmacher, J.2    Ghaderi, V.3
  • 41
    • 0036765747 scopus 로고    scopus 로고
    • Thymidylate synthase: A novel genetic determinant of plasma homocysteine and folate levels
    • Trinh BN, Ong C-N, Coetzee GA, Yu MC, Laird PW. Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels. Hum Genet 2002;111:299-302.
    • (2002) Hum Genet , vol.111 , pp. 299-302
    • Trinh, B.N.1    Ong, C.-N.2    Coetzee, G.A.3    Yu, M.C.4    Laird, P.W.5
  • 42
    • 0035187308 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the human reduced folate carrier: Characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers
    • Whetstine JR, Gifford AJ, Witt T, et al. Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers. Clin Cancer Res 2001;7:3416-22.
    • (2001) Clin Cancer Res , vol.7 , pp. 3416-3422
    • Whetstine, J.R.1    Gifford, A.J.2    Witt, T.3
  • 43
    • 0142150084 scopus 로고    scopus 로고
    • Polymorphism in the thymidylate synthase promoter enhancer region modifies the risk and survival of colorectal cancer
    • Chen J, Hunter DJ, Stampfer MJ, et al. Polymorphism in the thymidylate synthase promoter enhancer region modifies the risk and survival of colorectal cancer. Cancer Epidemiol Biomarkers Prev 2003;12:958-62.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , pp. 958-962
    • Chen, J.1    Hunter, D.J.2    Stampfer, M.J.3
  • 44
    • 0034909923 scopus 로고    scopus 로고
    • Polymorphisms and colorectal tumor risk
    • Houlston RS, Tomlinson IP. Polymorphisms and colorectal tumor risk. Gastroenterology 2001;121:282-301.
    • (2001) Gastroenterology , vol.121 , pp. 282-301
    • Houlston, R.S.1    Tomlinson, I.P.2
  • 46
    • 20144371859 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase 677C>T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynudeosides
    • Quinlivan EP, Davis SR, Shelnutt KP, et al. Methylenetetrahydrofolate reductase 677C>T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynudeosides. J Nutr 2005;135:389-96.
    • (2005) J Nutr , vol.135 , pp. 389-396
    • Quinlivan, E.P.1    Davis, S.R.2    Shelnutt, K.P.3
  • 47
    • 0015504248 scopus 로고
    • Rate of depurination of native deoxyribonucleic acid
    • Lindahl T, Nyberg B. Rate of depurination of native deoxyribonucleic acid. Biochemistry 1972;11:3610-8.
    • (1972) Biochemistry , vol.11 , pp. 3610-3618
    • Lindahl, T.1    Nyberg, B.2
  • 48
    • 0033152195 scopus 로고    scopus 로고
    • Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues
    • Nakamura J, Swenberg JA. Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues. Cancer Res 1999;59:2522-6.
    • (1999) Cancer Res , vol.59 , pp. 2522-2526
    • Nakamura, J.1    Swenberg, J.A.2
  • 49
    • 0026652116 scopus 로고
    • The biological chemistry of folate receptors
    • Antony AC. The biological chemistry of folate receptors. Blood 1992;79:2807-20.
    • (1992) Blood , vol.79 , pp. 2807-2820
    • Antony, A.C.1
  • 51
    • 0037176785 scopus 로고    scopus 로고
    • A 2-year, randomized, comparative, placebo-controlled study on the effects of raloxifene on lipoprotein(a) and homocysteine
    • Smolders RG, Vogelvang TE, Mijatovic V, et al. A 2-year, randomized, comparative, placebo-controlled study on the effects of raloxifene on lipoprotein(a) and homocysteine. Maturitas 2002;41:105-14.
    • (2002) Maturitas , vol.41 , pp. 105-114
    • Smolders, R.G.1    Vogelvang, T.E.2    Mijatovic, V.3
  • 52
    • 0036179337 scopus 로고    scopus 로고
    • Effects of hormone replacement therapy and methylenetetrahydrofolate reductase polymorphism on plasma folate and homocysteine levels in postmenopausal Japanese women
    • Somekawa Y, Kobayashi K, Tomura S, Aso T, Hamaguchi H. Effects of hormone replacement therapy and methylenetetrahydrofolate reductase polymorphism on plasma folate and homocysteine levels in postmenopausal Japanese women. Fertil Steril 2002;77:481-6.
    • (2002) Fertil Steril , vol.77 , pp. 481-486
    • Somekawa, Y.1    Kobayashi, K.2    Tomura, S.3    Aso, T.4    Hamaguchi, H.5
  • 53
    • 0034820702 scopus 로고    scopus 로고
    • Homocysteine in postmenopausal women and the importance of hormone replacement therapy
    • Mijatovic V, van der Mooren MJ. Homocysteine in postmenopausal women and the importance of hormone replacement therapy. Clin Chem Lab Med 2001;39:764-7.
    • (2001) Clin Chem Lab Med , vol.39 , pp. 764-767
    • Mijatovic, V.1    Van Der Mooren, M.J.2
  • 55
    • 10344260184 scopus 로고    scopus 로고
    • Opinion: CpG island methylator phenotype in cancer
    • Issa JP. Opinion: CpG island methylator phenotype in cancer. Nat Rev Cancer 2004;4:988-93.
    • (2004) Nat Rev Cancer , vol.4 , pp. 988-993
    • Issa, J.P.1
  • 56
    • 17444417521 scopus 로고    scopus 로고
    • Cancer epigenetics
    • Laird PW. Cancer epigenetics. Hum Mol Genet 2005;14 Spec No 1:R65-76.
    • (2005) Hum Mol Genet , vol.14 , Issue.SPEC. NO. 1
    • Laird, P.W.1
  • 58
    • 11244333118 scopus 로고    scopus 로고
    • A mathematical model of the folate cycle: New insights into folate homeostasis
    • Nijhout HF, Reed MC, Budu P, Ulrich CM. A mathematical model of the folate cycle: new insights into folate homeostasis. J Biol Chem 2004;279:55008-16.
    • (2004) J Biol Chem , vol.279 , pp. 55008-55016
    • Nijhout, H.F.1    Reed, M.C.2    Budu, P.3    Ulrich, C.M.4
  • 59
    • 16844369571 scopus 로고    scopus 로고
    • The need for a systematic approach to complex pathways in molecular epidemiology
    • Thomas DC. The need for a systematic approach to complex pathways in molecular epidemiology. Cancer Epidemiol Biomarkers Prev 2005;14:557-9.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 557-559
    • Thomas, D.C.1
  • 60
    • 4644243438 scopus 로고    scopus 로고
    • Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma
    • Skibola CF, Forrest MS, Coppede F, et al. Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma. Blood 2004;104:2155-62.
    • (2004) Blood , vol.104 , pp. 2155-2162
    • Skibola, C.F.1    Forrest, M.S.2    Coppede, F.3
  • 61
    • 0037093272 scopus 로고    scopus 로고
    • Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia
    • Skibola CF, Smith MT, Hubbard A, et al. Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia. Blood 2002;99:3786-91.
    • (2002) Blood , vol.99 , pp. 3786-3791
    • Skibola, C.F.1    Smith, M.T.2    Hubbard, A.3
  • 62
    • 0033607241 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults
    • Skibola CF, Smith MT, Kane E, et al. Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. Proc Natl Acad Sci U S A 1999;96:12810-5.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12810-12815
    • Skibola, C.F.1    Smith, M.T.2    Kane, E.3
  • 63
    • 0035957379 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia
    • Wiemels JL, Smith RN, Taylor GM, et al. Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia. Proc Natl Acad Sci U S A 2001;98: 4004-9.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4004-4009
    • Wiemels, J.L.1    Smith, R.N.2    Taylor, G.M.3
  • 64
    • 2942754073 scopus 로고    scopus 로고
    • Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: The Hordaland Homocysteine Study
    • Nurk E, Tell GS, Refsum H, Ueland PM, Vollset SE. Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: the Hordaland Homocysteine Study. Am J Med 2004;117:26-31.
    • (2004) Am J Med , vol.117 , pp. 26-31
    • Nurk, E.1    Tell, G.S.2    Refsum, H.3    Ueland, P.M.4    Vollset, S.E.5
  • 66
    • 0035552975 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene: Clinical consequences
    • Schwahn B, Rozen R. Polymorphisms in the methylenetetrahydrofolate reductase gene: clinical consequences. Am J Pharmacogenomics 2001;1:189-201.
    • (2001) Am J Pharmacogenomics , vol.1 , pp. 189-201
    • Schwahn, B.1    Rozen, R.2
  • 67
    • 0036890065 scopus 로고    scopus 로고
    • Homocysteine determinants and the evidence to what extent homocysteine determines the risk of coronary heart disease
    • De Bree A, Verschuren WM, Kromhout D, Kluijtmans LA, Blom HJ. Homocysteine determinants and the evidence to what extent homocysteine determines the risk of coronary heart disease. Pharmacol Rev 2002;54:599-618.
    • (2002) Pharmacol Rev , vol.54 , pp. 599-618
    • De Bree, A.1    Verschuren, W.M.2    Kromhout, D.3    Kluijtmans, L.A.4    Blom, H.J.5
  • 68
    • 15244348759 scopus 로고    scopus 로고
    • Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism
    • James SJ, Cutler P, Melnyk S, et al. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr 2004;80:1611-7.
    • (2004) Am J Clin Nutr , vol.80 , pp. 1611-1617
    • James, S.J.1    Cutler, P.2    Melnyk, S.3


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