2,3-cis-procyanidins elicit endothelium-dependent relaxation in porcine coronary arteries via activation of the PI3/Akt kinase signaling pathway

Journal of Agricultural and Food Chemistry

Volumn 61, Issue 40, 2013, Pages 9609-9616

  Kaufeld, Aurica M ^a   Pertz, Heinz H ^a   Kolodziej, Herbert ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

2,3 cis procyanidins; coronary heart disease; EDHF; Nelia meyeri; NO; PI3 Akt kinase; relaxation; ROS; superoxide anion

Indexed keywords

CORONARY HEART DISEASE; EDHF; NELIA MEYERI; PI3/AKT KINASE; PROCYANIDINS; RELAXATION; ROS; SUPEROXIDE ANIONS;

DISEASES; ENZYMES; NOBELIUM; O RINGS; OXYGEN;

FLAVONOIDS;

BIFLAVONOID; BIOLOGICAL FACTOR; CATECHIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIUM DEPENDENT HYPERPOLARIZATION FACTOR; ENDOTHELIUM-DEPENDENT HYPERPOLARIZATION FACTOR; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; POLYPHENOL; PROANTHOCYANIDIN; PROCYANIDIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

ANIMAL; ARTICLE; CORONARY BLOOD VESSEL; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; OXIDATION REDUCTION REACTION; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SWINE; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM;

ANIMALS; BIFLAVONOIDS; BIOLOGICAL FACTORS; CATECHIN; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATION-REDUCTION; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; POLYPHENOLS; PROANTHOCYANIDINS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SWINE;

EID: 84885445133     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf402460m     Document Type: Article

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