Procyanidin-rich fractions from Parkia biglobosa (Mimosaceae) leaves cause redox-sensitive endothelium-dependent relaxation involving NO and EDHF in porcine coronary artery

Journal of Ethnopharmacology

Volumn 132, Issue 1, 2010, Pages 246-250

  Tokoudagba, Jean Marie ^a,b   Auger, Cyril ^a   Bréant, Lise ^a   N'Gom, Saliou ^a   Chabert, Philippe ^a   Idris Khodja, Noureddine ^a   Gbaguidi, Fernand ^b   Gbenou, Joachim ^b   Moudachirou, Mansourou ^b   Lobstein, Annelise ^a   Schini Kerth, Valérie B ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b UNIVERSITY OF ABOMEY CALAVI   (Benin)

Author keywords

Coronary artery; Endothelium; Parkia biglobosa (Mimosaceae); Polyphenols; Procyanidins; Vasorelaxant

Indexed keywords

ACETIC ACID ETHYL ESTER; ALCOHOL; BUTANOL; CATECHIN; ELLAGITANNIN; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; FLAVONOID; NITRIC OXIDE; PARKIA BIGLOBOSA EXTRACT; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; POLYPHENOL; PROCYANIDIN; TANNIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; FRACTIONATION; LIQUID LIQUID EXTRACTION; MEDICINAL PLANT; NONHUMAN; OXIDATION REDUCTION REACTION; PARKIA BIGLOBOSA; PLANT LEAF; SWINE;

ANIMALS; BENIN; BIFLAVONOIDS; BIOLOGICAL FACTORS; CATECHIN; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; NITRIC OXIDE; OXIDATION-REDUCTION; PLANT EXTRACTS; PLANT LEAVES; PLANTS, MEDICINAL; PROANTHOCYANIDINS; SWINE; VASODILATION; VASODILATOR AGENTS;

FABACEAE; PARKIA BIGLOBOSA; SUS;

EID: 77957798792     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2010.08.031     Document Type: Article

References (29)

1. Addo J., Smeeth L., Leon D.A. Hypertension in sub-Saharan Africa: a systematic review. Hypertension 2007, 50:1012-1018.
2. Andriambeloson E., Magnier C., Haan-Archipoff G., Lobstein A., Anton R., Beretz A., Stoclet J.C., Andriantsitohaina R. Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta. Journal of Nutrition 1998, 128:1053-1058.
3. Anselm E., Socorro V.F., Dal-Ros S., Schott C., Bronner C., Schini-Kerth V.B. Crataegus special extract WS 1442 causes endothelium-dependent relaxation via a redox-sensitive Src- and Akt-dependent activation of endothelial NO synthase but not via activation of estrogen receptors. Journal of Cardiovascular Pharmacology 2009, 53:253-260.
4. Assane M., Baba Moussa R., Bassene E., Sere A. Antihypertensive action of Parkia biglobosa (Jacq) Benth seeds in the rat. Dakar Médical 1993, 38:49-54.
5. Auger C., Chataigneau T., Schini-Kerth V.B. Vascular protection by grape-derived polyphenols. Agro Food Industry Hi-Tech 2009, 20:38-40.
6. Azokpota P., Hounhouigan D.J., Nago M.C. Microbiological and chemical changes during the fermentation of African locust bean (Parkia biglobosa) to produce afitin, iru and sonru, three traditional condiments produced in Benin. International Journal of Food Microbiology 2006, 107:304-309.
7. Burkill H.M. The useful plants of West Tropical Africa, vol. 3 1995, Families J-L. Royal Botanic Gardens, Kew. 2nd edition.
8. Cienfuegos-Jovellanos E., Quinones M.M., Muguerza B., Moulay L., Miguel M., Aleixandre A. Antihypertensive effect of a polyphenol-rich cocoa powder industrially processed to preserve the original flavonoids of the cocoa beans. Journal of Agricultural and Food Chemistry 2009, 57:6156-6162.
9. Fitzpatrick D.F., Bing B., Maggi D.A., Fleming R.C., O'Malley R.M. Vasodilating procyanidins derived from grape seeds. Annals of the New York Academy of Sciences 2002, 957:78-89.
10. Grassi D., Necozione S., Lippi C., Croce G., Valeri L., Pasqualetti P., Desideri G., Blumberg J.B., Ferri C. Cocoa reduces blood pressure and insulin resistance and improves endothelium-dependent vasodilation in hypertensives. Hypertension 2005, 46:398-405.
11. Gronhaug T.E., Glaeserud S., Skogsrud M., Ballo N., Bah S., Diallo D., Paulsen B.S. Ethnopharmacological survey of six medicinal plants from Mali, West Africa. Journal of Ethnobiology and Ethnomedicine 2008, 4:26.
12. Hopkins H.C. The taxonomy, reproductive biology and economic potential of Parkia (Leguminosae: Mimosoideae) in Africa and Madagascar. Botanical Journal of the Linnean Society 1983, 87:135-167.
13. Kane M.O., Sarr M., Gueye P.M., Ndiaye C.A.B., Diaw M., Ba A., Sar F.B., Sall Diallo A. Vascular relaxant effects of a hydroalcoholic extract of bark of Parkia biglobosa (Mimosaceae). ScienceLib 2009, 2.
14. Karim M., McCormick K., Kappagoda C.T. Effects of cocoa extracts on endothelium-dependent relaxation. Journal of Nutrition 2000, 130:2105S-2108S.
15. Kassi Y., Aka K., Abo K., Mea A., Néné Bi S., Ehilé E. Effet antihypertensif d'un extrait aqueux d'écorce de tronc de Parkia biglobosa (Mimosaceae) sur la pression artérielle de lapin. Science Nature 2008, 5:133-143.
16. Madeira S.V., Auger C., Anselm E., Chataigneau M., Chataigneau T., Soares de Moura R., Schini-Kerth V.B. eNOS activation induced by a polyphenol-rich grape skin extract in porcine coronary arteries. Journal of Vascular Research 2009, 46:406-416.
17. Magos G.A., Mateos J.C., Páez E., Fernández G., Lobato C., Márquez C., Enríquez R.G. Hypotensive and vasorelaxant effects of the procyanidin fraction from Guazuma ulmifolia bark in normotensive and hypertensive rats. Journal of Ethnopharmacology 2008, 117:58-68.
18. Mensah G.A. Epidemiology of stroke and high blood pressure in Africa. Heart 2008, 94:697-705.
19. Ndiaye M., Chataigneau M., Lobysheva I., Chataigneau T., Schini-Kerth V.B. Red wine polyphenol-induced, endothelium-dependent NO-mediated relaxation is due to the redox-sensitive PI3-kinase/Akt-dependent phosphorylation of endothelial NO-synthase in the isolated porcine coronary artery. FASEB Journal 2005, 19:455-457.
20. Odetola A.A., Akinloye O., Egunjobi C., Adekunle W.A., Ayoola A.O. Possible antidiabetic and antihyperlipidaemic effect of fermented Parkia biglobosa (Jacq) extract in alloxan-induced diabetic rats. Clinical and Experimental Pharmacology and Physiology 2006, 33:808-812.
21. Schini-Kerth V.B., Auger C., Kim J.H., Etienne-Selloum N., Chataigneau T. Nutritional improvement of the endothelial control of vascular tone by polyphenols: role of NO and EDHF. Pflügers Archiv European Journal of Physiology 2010, 459:853-862.
22. Schmitt C.A., Dirsch V.M. Modulation of endothelial nitric oxide by plant-derived products. Nitric oxide 2009, 21:77-91.
23. Seedat Y.K., Rosenthal T. Meeting the challenges of hypertension in sub-Saharan Africa. Cardiovascular Journal of South Africa 2006, 17:47-48.
24. Singleton V.L., Orthifer R., Lamuela-Raventos R.M. Analysis of total phenols and other oxidation substrates and oxidants by means of Folin-Ciocalteu. Methods in Enzymology 1999, 299:152-178.
25. Soares de Moura R., Costa Viana F.S., Souza M.A., Kovary K., Guedes D.C., Oliveira E.P., Rubenich L.M., Carvalho L.C., Oliveira R.M., Tano T., Gusmao Correia M.L. Antihypertensive, vasodilator and antioxidant effects of a vinifera grape skin extract. Journal of Pharmacy and Pharmacology 2002, 54:1515-1520.
26. Sodjinou R, Agueh V., Fayomi B., Delisle H. Obesity and cardio-metabolic risk factors in urban adults of Benin: relationship with socio-economic status, urbanisation, and lifestyle patterns. BMC Public Health 2008, 8:84.
27. Tokoudagba J.-M., Chabert P., Auger C., N'Gom S., Gbenou J., Moudachirou M., Schini-Kerth V., Lobstein A. Recherche de plantes à potentialités antihypertensives dans la biodiversité béninoise. Ethnopharmacologia 2010, 44:32-41.
28. Tringali C., Spatafora C., Longo O.D. Bioactive constituents of the bark of Parkia biglobosa. Fitoterapia 2000, 71:118-125.
29. Udobi C.E., Onaolapo J.A. Phytochemical analysis and antibacterial evaluation of leaf stem bark and root of the African locust bean (Parkia biglobosa). Journal of Medicinal Plants Research 2009, 3:338-344.