메뉴 건너뛰기




Volumn 23, Issue 4, 2013, Pages 255-267

Aerosol generation using nanometer liposome suspensions for pulmonary drug delivery applications

Author keywords

Aerosol surface charge; Aggregation; Leakage; Membrane rupture; Size distribution; Systemic drug

Indexed keywords

CIPROFLOXACIN; DOXORUBICIN; DRUG CARRIER; LIPOSOME;

EID: 84885441526     PISSN: 08982104     EISSN: 15322394     Source Type: Journal    
DOI: 10.3109/08982104.2013.802332     Document Type: Review
Times cited : (23)

References (130)
  • 1
    • 84860600422 scopus 로고    scopus 로고
    • Liposomal drug carrier systems for inhalation treatment of lung cancer
    • Saarbrücken, der universität des saarlandes
    • Anabousi VS. (2006). Liposomal drug carrier systems for inhalation treatment of lung cancer. Chemie, pharmazie, bio- und werkstoffwissenschaften. Saarbrücken, der universität des saarlandes.
    • (2006) Chemie, Pharmazie, Bio- Und Werkstoffwissenschaften
    • Anabousi, V.S.1
  • 2
    • 42649137232 scopus 로고    scopus 로고
    • Targeted delivery of nanoparticles for the treatment of lung diseases
    • Azarmi S, Roa WH, Loebenberg R. (2008). Targeted delivery of nanoparticles for the treatment of lung diseases. Adv Drug Deliv Rev 60:863-75.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 863-875
    • Azarmi, S.1    Roa, W.H.2    Loebenberg, R.3
  • 3
    • 85012373035 scopus 로고
    • Diffusion of univalent ions across the lamellae of swollen phospholipids
    • Bangham AD, Standish MM, Watkins JC. (1965). Diffusion of univalent ions across the lamellae of swollen phospholipids. J Mol Biol 13: 38-252.
    • (1965) J Mol Biol , vol.13 , pp. 38-252
    • Bangham, A.D.1    Standish, M.M.2    Watkins, J.C.3
  • 4
    • 67549106817 scopus 로고    scopus 로고
    • Lung deposition of a liposomal cyclosporine a inhalation solution in patients after lung transplantation
    • Behr J, Zimmermann G, Baumgartner R, et al. (2009). Lung deposition of a liposomal cyclosporine a inhalation solution in patients after lung transplantation. J Aerosol Med Pulmonary Drug Deliv 22:121-29.
    • (2009) J Aerosol Med Pulmonary Drug Deliv , vol.22 , pp. 121-129
    • Behr, J.1    Zimmermann, G.2    Baumgartner, R.3
  • 6
    • 0026524869 scopus 로고
    • Drug encapsulation and release from multilamellar and unilamellar liposomes
    • Betageri GV, Parsons DL. (1992). Drug encapsulation and release from multilamellar and unilamellar liposomes. Int J Pharmaceut 81:235-41.
    • (1992) Int J Pharmaceut , vol.81 , pp. 235-241
    • Betageri, G.V.1    Parsons, D.L.2
  • 7
    • 0034738518 scopus 로고    scopus 로고
    • Interactions between cholesterol and lipids in bilayer membranes. Role of lipid headgroup and hydrocarbon chain-backbone linkage
    • DOI 10.1016/S0005-2736(00)00196-6, PII S0005273600001966
    • Bhattacharya S, Haldar S. (2000). Interactions between cholesterol and lipids in bilayer membranes. Role of lipid headgroup and hydrocarbon chain-backbone linkage. Biochim Biophys Acta-Biomembr 1467: 39-53. (Pubitemid 30621583)
    • (2000) Biochimica et Biophysica Acta - Biomembranes , vol.1467 , Issue.1 , pp. 39-53
    • Bhattacharya, S.1    Haldar, S.2
  • 9
    • 6344229772 scopus 로고    scopus 로고
    • Toxicological hazards of inhaled nanoparticles - Potential implications for drug delivery
    • DOI 10.1166/jnn.2004.081
    • Borm PJA, Kreyling W. (2004). Toxicological hazards of inhaled nanoparticles-potential implications for drug delivery. J Nanosci Nanotechnol 4:521-31. (Pubitemid 39387404)
    • (2004) Journal of Nanoscience and Nanotechnology , vol.4 , Issue.5 , pp. 521-531
    • Borm, P.J.A.1    Kreyling, W.2
  • 10
    • 0026761918 scopus 로고
    • Mechanisms, measurement, and significance of lung macrophage function
    • Brain JD. (1992). Mechanisms, measurement, and significance of lung macrophage function. Environ Health Perspect 97:5-10.
    • (1992) Environ Health Perspect , vol.97 , pp. 5-10
    • Brain, J.D.1
  • 11
    • 34250741919 scopus 로고    scopus 로고
    • Inhalation, deposition, and fate of insulin and other therapeutic proteins
    • Brain JD. (2007). Inhalation, deposition, and fate of insulin and other therapeutic proteins. Diabet Technol Therapeut 9:s4-15.
    • (2007) Diabet Technol Therapeut , vol.9
    • Brain, J.D.1
  • 12
    • 0032416796 scopus 로고    scopus 로고
    • Nebulisers for the generation of liposomal aerosols
    • DOI 10.1016/S0378-5173(98)00212-9, PII S0378517398002129
    • Bridges PA, Taylor KMG. (1998). Nebulisers for the generation of liposomal aerosols. Int J Pharmaceut 173:117-25. (Pubitemid 29027766)
    • (1998) International Journal of Pharmaceutics , vol.173 , Issue.1-2 , pp. 117-125
    • Bridges, P.A.1    Taylor, K.M.G.2
  • 13
    • 0034690943 scopus 로고    scopus 로고
    • An investigation of some of the factors influencing the jet nebulisation of liposomes
    • Bridges PA, Taylor KMG. (2000). An investigation of some of the factors influencing the jet nebulisation of liposomes. Int J Pharmaceut 204:69-79.
    • (2000) Int J Pharmaceut , vol.204 , pp. 69-79
    • Bridges, P.A.1    Taylor, K.M.G.2
  • 14
    • 78649648145 scopus 로고    scopus 로고
    • Lipid nanoparticles for the delivery of poorly watersoluble drugs
    • Bunjes H. (2010). Lipid nanoparticles for the delivery of poorly watersoluble drugs. J Pharm Pharmacol 62:1637-45.
    • (2010) J Pharm Pharmacol , vol.62 , pp. 1637-1645
    • Bunjes, H.1
  • 16
    • 0023874113 scopus 로고
    • Development of a systematic theory of suspension inhalation aerosols. II. Aggregates of monodisperse particles nebulized in polydisperse droplets
    • DOI 10.1016/0378-5173(88)90147-0
    • Chan HK, Gonda I. (1988). Development of a systematic theory of suspension inhalation aerosols. 2. Aggregates of monodisperse particles nebulized in polydisperse droplets. Int J Pharmaceut 41: 147-57. (Pubitemid 18017616)
    • (1988) International Journal of Pharmaceutics , vol.41 , Issue.1-2 , pp. 147-157
    • Chan, H.-K.1    Gonda, I.2
  • 17
    • 84857743488 scopus 로고    scopus 로고
    • Morphology and bilayer integrity of small liposomes during aerosol generation by airjet nebulisation
    • Chattopadhyay S, Ehrman SH, Bellare J, Venkataraman C. (2012). Morphology and bilayer integrity of small liposomes during aerosol generation by airjet nebulisation. J Nanoparticle Res 14:779, 1-15.
    • (2012) J Nanoparticle Res , vol.14 , Issue.779 , pp. 1-15
    • Chattopadhyay, S.1    Ehrman, S.H.2    Bellare, J.3    Venkataraman, C.4
  • 19
    • 0031239390 scopus 로고    scopus 로고
    • Experimental investigation of scaling laws for electrospraying: Dielectric constant effect
    • PII S0278682697000603
    • Chen DR, Pui DYH. (1997). Experimental investigation of scaling laws for electrospraying: dielectric constant effect. Aerosol Sci Technol 27: 367-80. (Pubitemid 27350020)
    • (1997) Aerosol Science and Technology , vol.27 , Issue.3 , pp. 367-380
    • Chen, D.-R.1    Pui, D.Y.H.2
  • 20
    • 0342740022 scopus 로고
    • Electrospraying of conducting liquids for monodisperse aerosol generation in the 4 nm to 1.8 mu-m diameter range
    • Chen DR, Pui DYH, Kaufman SL. (1995). Electrospraying of conducting liquids for monodisperse aerosol generation in the 4 nm to 1.8 mu-m diameter range. J Aerosol Sci 26:963-77.
    • (1995) J Aerosol Sci , vol.26 , pp. 963-977
    • Chen, D.R.1    Dyh, P.2    Kaufman, S.L.3
  • 21
    • 77957749362 scopus 로고    scopus 로고
    • Enhancing encapsulation efficiency of highly water-soluble antibiotic in poly(lactic-co-glycolic acid) nanoparticles: Modifications of standard nanoparticle preparation methods
    • Cheow WS, Hadinoto K. (2010). Enhancing encapsulation efficiency of highly water-soluble antibiotic in poly(lactic-co-glycolic acid) nanoparticles: modifications of standard nanoparticle preparation methods. Colloids Surfaces A-Physicochem Engin Aspect 370:79-86.
    • (2010) Colloids Surfaces A-Physicochem Engin Aspect , vol.370 , pp. 79-86
    • Cheow, W.S.1    Hadinoto, K.2
  • 22
    • 67349152120 scopus 로고    scopus 로고
    • Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery
    • Chono S, Fukuchi R, Seki T, Morimoto K. (2009). Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery. J Control Release 137:104-9.
    • (2009) J Control Release , vol.137 , pp. 104-119
    • Chono, S.1    Fukuchi, R.2    Seki, T.3    Morimoto, K.4
  • 24
    • 0028179827 scopus 로고
    • Modelling and deposition of inhaled powdered drug aerosols
    • Clark AR, Egan M. (1994). Modeling the deposition of inhaled powdered drug aerosols. J Aerosol Sci 25:175-86. (Pubitemid 285991)
    • (1994) Journal of Aerosol Science , vol.25 , Issue.1 , pp. 175-186
    • Clark, A.R.1    Egan, M.2
  • 25
    • 0024699359 scopus 로고
    • Electrostatic spraying of liquids in cone-jet mode
    • Cloupeau M, Prunetfoch B. (1989). Electrostatic spraying of liquids in cone-jet mode. J electrostatics 22:135-59.
    • (1989) J Electrostatics , vol.22 , pp. 135-159
    • Cloupeau, M.1    Prunetfoch, B.2
  • 26
    • 0000886004 scopus 로고
    • Deposition of inhaled charged ultrafine particles in a simple tracheal model
    • Cohen BS, Xiong JQ, Asgharian B, Ayres L. (1995). Deposition of inhaled charged ultrafine particles in a simple tracheal model. J Aerosol Sci 26:1149-60.
    • (1995) J Aerosol Sci , vol.26 , pp. 1149-1160
    • Cohen, B.S.1    Xiong, J.Q.2    Asgharian, B.3    Ayres, L.4
  • 27
    • 0030997918 scopus 로고    scopus 로고
    • Aerosol delivery of liposome-encapsulated ciprofloxacin: Aerosol characterization and efficacy against francisella tularensis infection in mice
    • Conley J, Yang HM, Wilson T, et al. (1997). Aerosol delivery of liposome-encapsulated ciprofloxacin: aerosol characterization and efficacy against francisella tularensis infection in mice. Antimicrob Agents Chemother 41:1288-92.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1288-2192
    • Conley, J.1    Yang, H.M.2    Wilson, T.3
  • 28
    • 0037426696 scopus 로고    scopus 로고
    • Nebulization of biodegradable nanoparticles: Impact of nebulizer technology and nanoparticle characteristics on aerosol features
    • DOI 10.1016/S0168-3659(02)00370-X, PII S016836590200370X
    • Dailey LA, Schmehl T, Gessler T, et al. (2003). Nebulization of biodegradable nanoparticles: impact of nebulizer technology and nanoparticle characteristics on aerosol features. J Control Rel 86: 131-44. (Pubitemid 35461980)
    • (2003) Journal of Controlled Release , vol.86 , Issue.1 , pp. 131-144
    • Dailey, L.A.1    Schmehl, T.2    Gessler, T.3    Wittmar, M.4    Grimminger, F.5    Seeger, W.6    Kissel, T.7
  • 31
    • 84867789269 scopus 로고    scopus 로고
    • Encapsulation and release behavior from lipid nanoparticles: Model study with nile red fluorophore
    • Delmas T, Fraichard A, Bayle P, et al. (2012). Encapsulation and release behavior from lipid nanoparticles: model study with nile red fluorophore. J Coll Sci Biotechnol 1:16-25.
    • (2012) J Coll Sci Biotechnol , vol.1 , pp. 16-25
    • Delmas, T.1    Fraichard, A.2    Bayle, P.3
  • 32
    • 33646436962 scopus 로고    scopus 로고
    • Increase of electrospray throughput using multiplexed microfabricated sources for the scalable generation of monodisperse droplets
    • Deng WW, Klemic JF, Li X, et al. (2006). Increase of electrospray throughput using multiplexed microfabricated sources for the scalable generation of monodisperse droplets. J Aerosol Sci 37:696-714.
    • (2006) J Aerosol Sci , vol.37 , pp. 696-714
    • Deng, W.W.1    Klemic, J.F.2    Li, X.3
  • 33
    • 0037038303 scopus 로고    scopus 로고
    • A facile method of delivery of liposomes by nebulization
    • DOI 10.1016/S0168-3659(02)00264-X, PII S016836590200264X
    • Desai TR, Hancock REW, Finlay WH. (2002). A facile method of delivery of liposomes by nebulization. J Control Rel 84:69-78. (Pubitemid 35223415)
    • (2002) Journal of Controlled Release , vol.84 , Issue.1-2 , pp. 69-78
    • Desai, T.R.1    Hancock, R.E.W.2    Finlay, W.H.3
  • 34
    • 0344083495 scopus 로고    scopus 로고
    • Delivery of liposomes in dry powder form: Aerodynamic dispersion properties
    • DOI 10.1016/j.ejps.2003.09.008
    • Desai TR, Hancock REW, Finlay WH. (2003). Delivery of liposomes in dry powder form: aerodynamic dispersion properties. Eur J Pharmaceut Sci 20:459-67. (Pubitemid 37491439)
    • (2003) European Journal of Pharmaceutical Sciences , vol.20 , Issue.4-5 , pp. 459-467
    • Desai, T.R.1    Hancock, R.E.W.2    Finlay, W.H.3
  • 35
    • 4644332315 scopus 로고    scopus 로고
    • New frontiers in aerosol delivery during mechanical ventilation
    • Dhand R. (2004). New frontiers in aerosol delivery during mechanical ventilation. Respiratory Care 49:666-77.
    • (2004) Respiratory Care , vol.49 , pp. 666-677
    • Dhand, R.1
  • 36
    • 0034603548 scopus 로고    scopus 로고
    • Response to different measles vaccine strains given by aerosol and subcutaneous routes to schoolchildren: A randomised trial
    • Dilraj A, Cutts FT, de castro JF, et al. (2000). Response to different measles vaccine strains given by aerosol and subcutaneous routes to schoolchildren: a randomised trial. Lancet 355:798-803. (Pubitemid 30128820)
    • (2000) Lancet , vol.355 , Issue.9206 , pp. 798-803
    • Dilraj, A.1    Cutts, F.T.2    De Castro, J.F.3    Wheeler, J.G.4    Brown, D.5    Roth, C.6    Coovadia, H.M.7    Bennett, J.V.8
  • 37
    • 13544253826 scopus 로고    scopus 로고
    • Device selection and outcomes of aerosol therapy: Evidence-based guidelines
    • Dolovich MB, Ahrens RC, Hess DR, et al. (2005). Device selection and outcomes of aerosol therapy: evidence-based guidelines. Chest 127: 335-71.
    • (2005) Chest , vol.127 , pp. 335-371
    • Dolovich, M.B.1    Ahrens, R.C.2    Hess, D.R.3
  • 38
    • 0031904113 scopus 로고    scopus 로고
    • Recent advances in pulmonary drug delivery using large, porous inhaled particles
    • Edwards DA, Ben-jebria A, Langer R. (1998). Recent advances in pulmonary drug delivery using large, porous inhaled particles. J Appl Physiol 85:379-85. (Pubitemid 28365799)
    • (1998) Journal of Applied Physiology , vol.85 , Issue.2 , pp. 379-385
    • Edwards, D.A.1    Ben-Jebria, A.2    Langer, R.3
  • 39
    • 33947144868 scopus 로고    scopus 로고
    • Physical stability and aerosol properties of liposomes delivered using an air-jet nebulizer and a novel micropump device with large mesh apertures
    • DOI 10.1016/j.ijpharm.2006.10.022, PII S0378517306008908
    • Elhissi AMA, Faizi M, Naji WF, et al. (2007). Physical stability and aerosol properties of liposomes delivered using an air-jet nebulizer and a novel micropump device with large mesh apertures. Int J Pharmaceut 334:62-70. (Pubitemid 46400313)
    • (2007) International Journal of Pharmaceutics , vol.334 , Issue.1-2 , pp. 62-70
    • Elhissi, A.M.A.1    Faizi, M.2    Naji, W.F.3    Gill, H.S.4    Taylor, K.M.G.5
  • 40
    • 26844457912 scopus 로고    scopus 로고
    • Number-concentration of nanoparticles in liposomal and polymeric multiparticulate preparations: Empirical and calculation methods
    • DOI 10.1016/j.biomaterials.2005.06.006, PII S0142961205005740
    • Epstein H, Afergan E, Moise T, et al. (2006). Number-concentration of nanoparticles in liposomal and polymeric multiparticulate preparations: empirical and calculation methods. Biomaterials 27:651-59. (Pubitemid 41464261)
    • (2006) Biomaterials , vol.27 , Issue.4 , pp. 651-659
    • Epstein, H.1    Afergan, E.2    Moise, T.3    Richter, Y.4    Rudich, Y.5    Golomb, G.6
  • 43
    • 0034223153 scopus 로고    scopus 로고
    • Aerosol device selection: Evidence to practice
    • Fink JB. (2000). Aerosol device selection: evidence to practice. Respiratory Care 45:874-85.
    • (2000) Respiratory Care , vol.45 , pp. 874-885
    • Fink, J.B.1
  • 45
    • 0028423981 scopus 로고
    • The size and charge of droplets in the electrospraying of polar liquids in cone-jet mode, and the minimum droplet size
    • Ganan-Calvo AM. (1994). The size and charge of droplets in the electrospraying of polar liquids in cone-jet mode, and the minimum droplet size. J Aerosol Sci 25:s309-10.
    • (1994) J Aerosol Sci , vol.25
    • Ganan-Calvo, A.M.1
  • 46
    • 58149177361 scopus 로고    scopus 로고
    • Inhaled liposomescurrent strategies and future challenges
    • Gaspar MM, Bakowsky U, Ehrhardt C. (2008). Inhaled liposomescurrent strategies and future challenges. J Biomed Nanotechnol 4: 245-57.
    • (2008) J Biomed Nanotechnol , vol.4 , pp. 245-257
    • Gaspar, M.M.1    Bakowsky, U.2    Ehrhardt, C.3
  • 47
    • 77149157841 scopus 로고    scopus 로고
    • Generation of liposome aerosols with the aeroneb pro and the aeroprobe nebulizers
    • Gaspar MM, Gobbo O, Ehrhardt C. (2010). Generation of liposome aerosols with the aeroneb pro and the aeroprobe nebulizers. J Liposome Res 20:55-61.
    • (2010) J Liposome Res , vol.20 , pp. 55-61
    • Gaspar, M.M.1    Gobbo, O.2    Ehrhardt, C.3
  • 48
    • 0024210630 scopus 로고
    • Small particle aerosols of enviroxime-containing liposomes
    • DOI 10.1016/0166-3542(88)90037-X
    • Gilbert BE, Six HR, Wilson S, et al. (1988). Small particle aerosols of enviroxime-containing liposomes. Antiviral Res 9:355-65. (Pubitemid 19001083)
    • (1988) Antiviral Research , vol.9 , Issue.6 , pp. 355-365
    • Gilbert, B.E.1    Six, H.R.2    Wilson, S.Z.3    Wyde, P.R.4    Knight, V.5
  • 49
    • 0036886253 scopus 로고    scopus 로고
    • The electrospray and its application to targeted drug inhalation
    • Gomez A. (2002). The electrospray and its application to targeted drug inhalation. Respiratory care 47:1419-31.
    • (2002) Respiratory Care , vol.47 , pp. 1419-2131
    • Gomez, A.1
  • 50
    • 0032101058 scopus 로고    scopus 로고
    • Production of protein nanoparticles by electrospray drying
    • DOI 10.1016/S0021-8502(97)10031-3, PII S0021850297100313
    • Gomez A, Bingham D, de Juan L, Tang K. (1998). Production of protein nanoparticles by electrospray drying. J Aerosol Sci 29:561-74. (Pubitemid 28263563)
    • (1998) Journal of Aerosol Science , vol.29 , Issue.5-6 , pp. 561-574
    • Gomez, A.1    Bingham, D.2    De Juan, L.3    Tang, K.4
  • 51
    • 84871590301 scopus 로고    scopus 로고
    • Interfacial organization of -carotene loaded lipid nanocapsules modelized by 2d rheological measurements and electrophoretic mobility
    • Gonnet M, Bastiat G, Ivanova T, Boury F. (2012). Interfacial organization of -carotene loaded lipid nanocapsules modelized by 2d rheological measurements and electrophoretic mobility. J Coll Sci Biotechnol 1:137-46.
    • (2012) J Coll Sci Biotechnol , vol.1 , pp. 137-146
    • Gonnet, M.1    Bastiat, G.2    Ivanova, T.3    Boury, F.4
  • 53
    • 0021797372 scopus 로고
    • Novel multilayered lipid vesicles-comparison of physical characteristics of multilamellar liposomes and stable plurilamellar vesicles
    • Gruner SM, Lenk RP, Janoff AS, Ostro MJ. (1985). Novel multilayered lipid vesicles-comparison of physical characteristics of multilamellar liposomes and stable plurilamellar vesicles. Biochemistry 24: 2833-42.
    • (1985) Biochemistry , vol.24 , pp. 2833-3242
    • Gruner, S.M.1    Lenk, R.P.2    Janoff, A.S.3    Ostro, M.J.4
  • 55
    • 29844458396 scopus 로고    scopus 로고
    • Carboxyfluorescein leakage from poly(ethylene glycol)-grafted liposomes induced by the interaction with serum
    • DOI 10.1248/cpb.54.80
    • Hashizaki K, Taguchi H, Sakai H, et al. (2006). Carboxyfluorescein leakage from poly(ethylene glycol)-grafted liposomes induced by the interaction with serum. Chem Pharmaceut Bull 54:80-84. (Pubitemid 43036754)
    • (2006) Chemical and Pharmaceutical Bulletin , vol.54 , Issue.1 , pp. 80-84
    • Hashizaki, K.1    Taguchi, H.2    Sakai, H.3    Abe, M.4    Saito, Y.5    Ogawa, N.6
  • 56
    • 0022889862 scopus 로고
    • Deposition of particles in the human respiratory tract in the size range 0. 005-15 mu m
    • DOI 10.1016/0021-8502(86)90035-2
    • Heyder J, Gebhart J, Rudolf G, et al. (1986). Deposition of particles in the human respiratory-tract in the size range 0.005-15-mu-m. J Aerosol Sci 17:811-25. (Pubitemid 17492310)
    • (1986) Journal of Aerosol Science , vol.17 , Issue.5 , pp. 811-825
    • Heyder, J.1    Gebhart, J.2    Rudolf, G.3    Schiller, C.F.4    Stahlhofen, W.5
  • 58
    • 79960984396 scopus 로고    scopus 로고
    • Modelling inhaled particle deposition in the human lung - A review
    • Hofmann W. (2011). Modelling inhaled particle deposition in the human lung-a review. J Aerosol Sci 42:693-724.
    • (2011) J Aerosol Sci , vol.42 , pp. 693-724
    • Hofmann, W.1
  • 59
    • 0025665731 scopus 로고
    • Monte-Carlo modeling of aerosol deposition in human lungs. 2. Deposition fractions and their sensitivity to parameter variations
    • Hofmann W, Koblinger L. (1990). Monte-Carlo modeling of aerosol deposition in human lungs. 2. Deposition fractions and their sensitivity to parameter variations. J Aerosol Sci 21:675-88.
    • (1990) J Aerosol Sci , vol.21 , pp. 675-688
    • Hofmann, W.1    Koblinger, L.2
  • 60
    • 61949094847 scopus 로고    scopus 로고
    • Charged droplet dynamics in the submicrometer size range
    • Hogan CJ, Biswas P, Chen DR. (2009). Charged droplet dynamics in the submicrometer size range. J Phys Chem B 113:970-76.
    • (2009) J Phys Chem B , vol.113 , pp. 970-976
    • Hogan, C.J.1    Biswas, P.2    Chen, D.R.3
  • 61
    • 32444446480 scopus 로고    scopus 로고
    • Charge reduced electrospray size spectrometry of mega- and gigadalton complexes: Whole viruses and virus fragments
    • DOI 10.1021/ac051571i
    • Hogan CJ, Kettleson EM, Ramaswami B, et al. (2006). Charge reduced electrospray size spectrometry of mega- and gigadalton complexes: whole viruses and virus fragments. Anal Chem 78:844-52. (Pubitemid 43228592)
    • (2006) Analytical Chemistry , vol.78 , Issue.3 , pp. 844-852
    • Hogan Jr., C.J.1    Kettleson, E.M.2    Ramaswami, B.3    Chen, D.-R.4    Biswas, P.5
  • 63
    • 78049472568 scopus 로고    scopus 로고
    • Size of thermosensitive liposomes influences content release
    • Hossann M, Wang TT, Wiggenhorn M, et al. (2010). Size of thermosensitive liposomes influences content release. J Control Rel 147:436-43.
    • (2010) J Control Rel , vol.147 , pp. 436-443
    • Hossann, M.1    Wang, T.T.2    Wiggenhorn, M.3
  • 64
    • 33744536662 scopus 로고    scopus 로고
    • Pulmonary delivery of insulin by liposomal carriers
    • Huang YY, Wang CH. (2006). Pulmonary delivery of insulin by liposomal carriers. J Control Rel 113:9-14.
    • (2006) J Control Rel , vol.113 , pp. 9-14
    • Huang, Y.Y.1    Wang, C.H.2
  • 65
    • 79955857306 scopus 로고    scopus 로고
    • Beclomethasone-loaded lipidic nanocarriers for pulmonary drug delivery: Preparation, characterization and in vitro drug release
    • Jaafar-Maalej C, Andrieu V, Elaissari A, Fessi H. (2011). Beclomethasone-loaded lipidic nanocarriers for pulmonary drug delivery: preparation, characterization and in vitro drug release. J Nanosci Nanotechnol 11:1841-51.
    • (2011) J Nanosci Nanotechnol , vol.11 , pp. 1841-2151
    • Jaafar-Maalej, C.1    Andrieu, V.2    Elaissari, A.3    Fessi, H.4
  • 66
    • 84865317556 scopus 로고    scopus 로고
    • Lipid-based carriers: Manufacturing and applications for pulmonary route
    • Jaafar-maalej C, Elaissari A, Fessi H. (2012). Lipid-based carriers: manufacturing and applications for pulmonary route. Expert Opin Drug Deliv 9:1111-27.
    • (2012) Expert Opin Drug Deliv , vol.9 , pp. 1111-1127
    • Jaafar-Maalej, C.1    Elaissari, A.2    Fessi, H.3
  • 67
    • 57349190655 scopus 로고    scopus 로고
    • Aggregation of nanosized colloidal silica in the presence of various alkali cations investigated by the electrospray technique
    • Johnson ACJH, Greenwood P, Hagstrom M, et al. (2008). Aggregation of nanosized colloidal silica in the presence of various alkali cations investigated by the electrospray technique. Langmuir 24: 12798-806.
    • (2008) Langmuir , vol.24 , pp. 12798-21806
    • Johnson, A.C.J.H.1    Greenwood, P.2    Hagstrom, M.3
  • 69
    • 27144481028 scopus 로고    scopus 로고
    • Solid Lipid Nanoparticles (SLN) and oil-loaded SLN studied by spectrofluorometry and raman spectroscopy
    • DOI 10.1007/s11095-005-7148-5
    • Jores K, Haberland A, Wartewig S, et al. (2005). Solid lipid nanoparticles (sln) and oil-loaded sln studied by spectrofluorometry and raman spectroscopy. Pharmaceut Res 22:1887-97. (Pubitemid 41504342)
    • (2005) Pharmaceutical Research , vol.22 , Issue.11 , pp. 1887-1897
    • Jores, K.1    Haberland, A.2    Wartewig, S.3    Mader, K.4    Mehnert, W.5
  • 70
    • 40849116134 scopus 로고    scopus 로고
    • Use of an electrospray for the generation of bacterial bioaerosols
    • Kim K, Kim W, Yun S, et al. (2008). Use of an electrospray for the generation of bacterial bioaerosols. J Aerosol Sci 39:365-72.
    • (2008) J Aerosol Sci , vol.39 , pp. 365-372
    • Kim, K.1    Kim, W.2    Yun, S.3
  • 71
    • 0021704080 scopus 로고
    • Dehydration-rehydration vesicles: A simple method for high yield drug entrapment in liposomes
    • DOI 10.1038/nbt1184-979
    • Kirby C, Gregoriadis G. (1984). Dehydration-rehydration vesicles-a simple method for high-yield drug entrapment in liposomes. Bio-technology 2:979-84. (Pubitemid 15090594)
    • (1984) Bio/Technology , vol.2 , Issue.11 , pp. 979-984
    • Kirby, C.1    Gergoriadis, G.2
  • 72
    • 33846071525 scopus 로고    scopus 로고
    • Iloprost-containing liposomes for aerosol application in pulmonary arterial hypertension: Formulation aspects and stability
    • DOI 10.1007/s11095-006-9141-z
    • Kleemann E, Schmehl T, Gessler T, et al. (2007). Iloprost-containing liposomes for aerosol application in pulmonary arterial hypertension: formulation aspects and stability. Pharmaceut Res 24:277-87. (Pubitemid 46072187)
    • (2007) Pharmaceutical Research , vol.24 , Issue.2 , pp. 277-287
    • Kleemann, E.1    Schmehl, T.2    Gessler, T.3    Bakowsky, U.4    Kissel, T.5    Seeger, W.6
  • 73
    • 78650047388 scopus 로고    scopus 로고
    • Optimal drug-aerosol delivery to predetermined lung sites
    • 011002
    • Kleinstreuer C, Zhang Z. (2011). Optimal drug-aerosol delivery to predetermined lung sites. J Heat Trans-Trans Asme 133:011002, 1-12.
    • (2011) J Heat Trans-Trans Asme , vol.133 , pp. 1-12
    • Kleinstreuer, C.1    Zhang, Z.2
  • 74
    • 0025587183 scopus 로고
    • Monte-Carlo modeling of aerosol deposition in human lungs. 1. Simulation of particle-transport in a stochastic lung structure
    • Koblinger L, Hofmann W. (1990). Monte-Carlo modeling of aerosol deposition in human lungs. 1. Simulation of particle-transport in a stochastic lung structure. J Aerosol Sci 21: 661-74.
    • (1990) J Aerosol Sci , vol.21 , pp. 661-674
    • Koblinger, L.1    Hofmann, W.2
  • 76
    • 0344513087 scopus 로고    scopus 로고
    • Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications
    • DOI 10.1046/j.1365-2125.2003.01892.x
    • Labiris NR, Dolovich MB. (2003). Pulmonary drug delivery. Part i: physiological factors affecting therapeutic effectiveness of aerosolized medications. Br J Clin Pharmacol 56:588-99. (Pubitemid 37491710)
    • (2003) British Journal of Clinical Pharmacology , vol.56 , Issue.6 , pp. 588-599
    • Labiris, N.R.1    Dolovich, M.B.2
  • 77
    • 84874943077 scopus 로고    scopus 로고
    • Preparation, characterization and applications of liposomes: State of the art
    • Laouini A, Jaafar-maalej C, Limayem-blouza I, et al. (2012). Preparation, characterization and applications of liposomes: state of the art. J Coll Sci Biotechnol 1:147-68.
    • (2012) J Coll Sci Biotechnol , vol.1 , pp. 147-168
    • Laouini, A.1    Jaafar-Maalej, C.2    Limayem-Blouza, I.3
  • 80
    • 21344459885 scopus 로고    scopus 로고
    • Effect of jet nebulization on DNA: Identifying the dominant degradation mechanism and mitigation methods
    • DOI 10.1016/j.jaerosci.2004.11.017, PII S0021850204004057
    • Lentz YK, Worden LR, Anchordoquy TJ, Lengsfeld CS. (2005). Effect of jet nebulization on DNA: identifying the dominant degradation mechanism and mitigation methods. J Aerosol Sci 36: 973-90. (Pubitemid 40968174)
    • (2005) Journal of Aerosol Science , vol.36 , Issue.8 , pp. 973-990
    • Lentz, Y.K.1    Worden, L.R.2    Anchordoquy, T.J.3    Lengsfeld, C.S.4
  • 82
    • 54949136128 scopus 로고    scopus 로고
    • Characterization of nebulized liposomal amikacin (arikace (tm)) as a function of droplet size
    • Li ZL, Zhang YL, Wurtz W, et al. (2008). Characterization of nebulized liposomal amikacin (arikace (tm)) as a function of droplet size. J Aerosol Med Pulmon Drug Deliv 21:245-53.
    • (2008) J Aerosol Med Pulmon Drug Deliv , vol.21 , pp. 245-253
    • Li, Z.L.1    Zhang, Y.L.2    Wurtz, W.3
  • 83
    • 0031737851 scopus 로고    scopus 로고
    • Membrane fusion and rupture in liposomes: Effect of biodegradable pH- sensitive surfactants
    • DOI 10.1007/s002329900445
    • Liang E, Hughes JA. (1998). Membrane fusion and rupture in liposomes: effect of biodegradable ph-sensitive surfactants. J Memb Biol 166: 37-49. (Pubitemid 28516082)
    • (1998) Journal of Membrane Biology , vol.166 , Issue.1 , pp. 37-49
    • Liang, E.1    Hughes, J.A.2
  • 84
    • 0025044199 scopus 로고
    • Effects of fiber characteristics on lung deposition, retention, and disease
    • Lippmann M. (1990). Effects of fiber characteristics on lung deposition, retention, and disease. Environ Health Perspect 88:311-17. (Pubitemid 20352988)
    • (1990) Environmental Health Perspectives , vol.88 , pp. 311-317
    • Lippmann, M.1
  • 85
    • 0027398639 scopus 로고
    • Pulmonary delivery of free and liposomal insulin
    • DOI 10.1023/A:1018934810512
    • Liu FY, Shao ZZ, Kildsig DO, Mitra AK. (1993). Pulmonary delivery of free and liposomal insulin. Pharmaceut Res 10:228-32. (Pubitemid 23041736)
    • (1993) Pharmaceutical Research , vol.10 , Issue.2 , pp. 228-232
    • Liu, F.1    Kildsig, D.O.2    Mitra, A.K.3    Shao, Z.4
  • 88
    • 0029586446 scopus 로고
    • Nebulization of fluids of different physicochemical properties with air-jet and ultrasonic nebulizers
    • Mccallion ONM, Taylor KMG, Thomas M, Taylor AJ. (1995). Nebulization of fluids of different physicochemical properties with air-jet and ultrasonic nebulizers. Pharmaceut Res 12: 1682-88.
    • (1995) Pharmaceut Res , vol.12 , pp. 1682-2188
    • McCallion, O.N.M.1    Taylor, K.M.G.2    Thomas, M.3    Taylor, A.J.4
  • 90
    • 0343267783 scopus 로고    scopus 로고
    • Nebulisation of monodisperse latex sphere suspensions in air-jet and ultrasonic nebulisers
    • DOI 10.1016/0378-5173(96)04449-3
    • Mccallion ONM, Taylor KMG, Thomas M, Taylor AJ. (1996b). Nebulisation of monodisperse latex sphere suspensions in air-jet and ultrasonic nebulisers. Int J Pharmaceut 133:203-14. (Pubitemid 26160846)
    • (1996) International Journal of Pharmaceutics , vol.133 , Issue.1-2 , pp. 203-214
    • Mc Calliona, O.N.M.1    Taylor, K.M.G.2    Thomas, M.3    Taylor, A.J.4
  • 91
    • 0020254113 scopus 로고
    • Deposition of chargedparticles in the human airways
    • Melandri C, Tarroni G, Prodi V, et al. (1983). Deposition of chargedparticles in the human airways. J Aerosol Sci 14:184-86.
    • (1983) J Aerosol Sci , vol.14 , pp. 184-186
    • Melandri, C.1    Tarroni, G.2    Prodi, V.3
  • 93
    • 10044249828 scopus 로고    scopus 로고
    • Eulerian modelling of lung deposition with sectional representation of aerosol dynamics
    • DOI 10.1016/j.jaerosci.2004.08.008, PII S0021850204003283
    • Mitsakou C, Helmis C, Housiadas C. (2005). Eulerian modelling of lung deposition with sectional representation of aerosol dynamics. J Aerosol Sci 36:75-94. (Pubitemid 39601425)
    • (2005) Journal of Aerosol Science , vol.36 , Issue.1 , pp. 75-94
    • Mitsakou, C.1    Helmis, C.2    Housiadas, C.3
  • 94
    • 0028630804 scopus 로고
    • Why do medical nebulizers differ in their output and particle-size characteristics
    • Nerbrink O, Dahlback M, Hansson HC. (1994). Why do medical nebulizers differ in their output and particle-size characteristics. J Aerosol Med-Depos Clear Effect Lung 7:259-76.
    • (1994) J Aerosol Med-Depos Clear Effect Lung , vol.7 , pp. 259-276
    • Nerbrink, O.1    Dahlback, M.2    Hansson, H.C.3
  • 95
    • 0028212069 scopus 로고
    • Some functional-aspects of air-jet nebulizers
    • Niven RW, Brain JD. (1994). Some functional-aspects of air-jet nebulizers. Int J Pharmaceut 104:73-85.
    • (1994) Int J Pharmaceut , vol.104 , pp. 73-85
    • Niven, R.W.1    Brain, J.D.2
  • 96
    • 0026513264 scopus 로고
    • Nebulization of liposomes 3. The effects of operating-conditions and local environment
    • Niven RW, Carvajal TM, Schreier H. (1992). Nebulization of liposomes 3. The effects of operating-conditions and local environment. Pharmaceut Res 9:515-20.
    • (1992) Pharmaceut Res , vol.9 , pp. 515-520
    • Niven, R.W.1    Carvajal, T.M.2    Schreier, H.3
  • 97
    • 0025245057 scopus 로고
    • Nebulization of liposomes. 1. Effects of lipid-composition
    • Niven RW, Schreier H. (1990). Nebulization of liposomes. 1. Effects of lipid-composition. Pharmaceut Res 7:1127-33.
    • (1990) Pharmaceut Res , vol.7 , pp. 1127-1133
    • Niven, R.W.1    Schreier, H.2
  • 98
    • 0025911331 scopus 로고
    • Nebulization of liposomes. 2. The effects of size and modeling of soute release profiles
    • Niven RW, Speer M, Schreier H. (1991). Nebulization of liposomes. 2. The effects of size and modeling of soute release profiles. Pharmaceut Res 8:217-21.
    • (1991) Pharmaceut Res , vol.8 , pp. 217-221
    • Niven, R.W.1    Speer, M.2    Schreier, H.3
  • 99
    • 0030916624 scopus 로고    scopus 로고
    • The science of nebulised drug delivery
    • Ocallaghan C, Barry PW. (1997). The science of nebulised drug delivery. Thorax 52:s31-44. (Pubitemid 27239451)
    • (1997) Thorax , vol.52 , Issue.SUPPL. 2
    • O'Callaghan, C.1    Barry, P.W.2
  • 100
    • 33947212925 scopus 로고    scopus 로고
    • Phase i study of inhaled doxorubicin for patients with metastatic tumors to the lungs
    • Otterson GA, Villalona-calero MA, Sharma S, et al. (2007). Phase i study of inhaled doxorubicin for patients with metastatic tumors to the lungs. Clin Canc Res 13:1246-52.
    • (2007) Clin Canc Res , vol.13 , pp. 1246-2152
    • Otterson, G.A.1    Villalona-Calero, M.A.2    Sharma, S.3
  • 101
    • 0343058935 scopus 로고    scopus 로고
    • Mechanisms of macromolecule absorption by the lungs
    • DOI 10.1016/0169-409X(95)00113-L
    • Patton JS. (1996). Mechanisms of macromolecule absorption by the lungs. Adv Drug Deliv Rev 19:3-36. (Pubitemid 26167852)
    • (1996) Advanced Drug Delivery Reviews , vol.19 , Issue.1 , pp. 3-36
    • Patton, J.S.1
  • 102
    • 78650225640 scopus 로고    scopus 로고
    • The particle has landedcharacterizing the fate of inhaled pharmaceuticals
    • Patton JS, Brain JD, Davies LA, et al. (2010). The particle has landedcharacterizing the fate of inhaled pharmaceuticals. J Aerosol Med Pulmon Drug Deliv 23:s71-87.
    • (2010) J Aerosol Med Pulmon Drug Deliv , vol.23
    • Patton, J.S.1    Brain, J.D.2    Davies, L.A.3
  • 104
    • 33845906339 scopus 로고    scopus 로고
    • Inhaling medicines: Delivering drugs to the body through the lungs
    • DOI 10.1038/nrd2153, PII NRD2153
    • Patton JS, Byron PR. (2007). inhaling medicines: delivering drugs to the body through the lungs. Nat Rev Drug Discov 6:67-74. (Pubitemid 46020287)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.1 , pp. 67-74
    • Patton, J.S.1    Byron, P.R.2
  • 105
    • 0141562799 scopus 로고    scopus 로고
    • Absorption and metabolic effect of inhaled insulin. Intrapatient variability after inhalation via the aerodose insulin inhaler in patients with type 2 diabetes
    • DOI 10.2337/diacare.25.12.2276
    • Perera AD, Kapitza C, Nosek L, et al. (2002). Absorption and metabolic effect of inhaled insulin-intrapatient variability after inhalation via the aerodose insulin inhaler in patients with type 2 diabetes. Diabetes Care 25:2276-81. (Pubitemid 41071040)
    • (2002) Diabetes Care , vol.25 , Issue.12 , pp. 2276-2281
    • Perera, A.D.1    Kapitza, C.2    Nosek, L.3    Fishman, R.S.4    Shapiro, D.A.5    Heise, T.6    Heinemann, L.7
  • 107
    • 1242351697 scopus 로고    scopus 로고
    • Comparison of Lung Deposition in Two Types of Nebulization: Intrapulmonary Percussive Ventilation vs Jet Nebulization
    • DOI 10.1378/chest.125.2.502
    • Reychler G, Keyeux A, Cremers C, et al. (2004). Comparison of lung deposition in two types of nebulization-intrapulmonary percussive ventilation vs jet nebulization. Chest 125:502-08. (Pubitemid 38223629)
    • (2004) Chest , vol.125 , Issue.2 , pp. 502-508
    • Reychler, G.1    Keyeux, A.2    Cremers, C.3    Veriter, C.4    Rodenstein, D.O.5    Liistro, G.6
  • 108
    • 0029953050 scopus 로고    scopus 로고
    • Drug absorption sites in the gastrointestinal tract and dosage forms for site-specific delivery
    • DOI 10.1016/0378-5173(96)85200-8
    • Rouge N, Buri P, Doelker E. (1996). Drug absorption sites in the gastrointestinal tract and dosage forms for site-specific delivery. Int J Pharmaceut 136:117-39. (Pubitemid 26199405)
    • (1996) International Journal of Pharmaceutics , vol.136 , Issue.1-2 , pp. 117-139
    • Rouge, N.1    Buri, P.2    Doelker, E.3
  • 111
    • 0032212709 scopus 로고    scopus 로고
    • Mechanisms and factors affecting intrapulmonary particle deposition: Implications for efficient inhalation therapies
    • PII S1461534798000893
    • Schulz H. (1998). Mechanisms and factors affecting intrapulmonary particle deposition: implications for efficient inhalation therapies. Pharmaceut Sci Technol Today 1:336-44. (Pubitemid 28526962)
    • (1998) Pharmaceutical Science and Technology Today , vol.1 , Issue.8 , pp. 336-344
    • Schulz, H.1
  • 112
    • 57349139366 scopus 로고    scopus 로고
    • Biodistribution of 1.4-and 18-nm gold particles in rats
    • Semmler-behnke M, Kreyling WG, Lipka J, et al. (2008). Biodistribution of 1.4-and 18-nm gold particles in rats. Small 4:2108-11.
    • (2008) Small , vol.4 , pp. 2108-2211
    • Semmler-Behnke, M.1    Kreyling, W.G.2    Lipka, J.3
  • 113
    • 0030795298 scopus 로고    scopus 로고
    • Liposomes in drug delivery: Progress and limitations
    • DOI 10.1016/S0378-5173(97)00135-X, PII S037851739700135X
    • Sharma A, Sharma US. (1997). Liposomes in drug delivery: progress and limitations. Int J Pharmaceut 154:123-40. (Pubitemid 27351317)
    • (1997) International Journal of Pharmaceutics , vol.154 , Issue.2 , pp. 123-140
    • Sharma, A.1    Sharma, U.S.2
  • 114
    • 0016555280 scopus 로고
    • Particle sizing of aerosols by single-particle observation in a sedimentation cell
    • Stahlhofen W, Armbruster L, Gebhart J, Grein E. (1975). Particle sizing of aerosols by single-particle observation in a sedimentation cell. Atmos Environ 9:851-57.
    • (1975) Atmos Environ , vol.9 , pp. 851-857
    • Stahlhofen, W.1    Armbruster, L.2    Gebhart, J.3    Grein, E.4
  • 115
    • 0006847485 scopus 로고
    • Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation
    • Szoka F, Papahadjopoulos D. (1978). Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation. Proc Natl Acad Sci USA 75:4194-98.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 4194-4498
    • Szoka, F.1    Papahadjopoulos, D.2
  • 116
    • 0028513140 scopus 로고
    • Generation by electrospray of monodisperse water droplets for targeted drug-delivery by inhalation
    • Tang K, Gomez A. (1994). Generation by electrospray of monodisperse water droplets for targeted drug-delivery by inhalation. J Aerosol Sci 25:1237-49.
    • (1994) J Aerosol Sci , vol.25 , pp. 1237-2149
    • Tang, K.1    Gomez, A.2
  • 117
    • 33644617924 scopus 로고    scopus 로고
    • Dry powder inhaler formulation
    • Telko MJ, Hickey AJ. (2005). Dry powder inhaler formulation. Respiratory Care 50:1209-27.
    • (2005) Respiratory Care , vol.50 , pp. 1209-2127
    • Telko, M.J.1    Hickey, A.J.2
  • 119
    • 0037150479 scopus 로고    scopus 로고
    • A randomized trial demonstrating successful boosting responses following simultaneous aerosols of measles and rubella (mr) vaccines in school age children
    • Valdespino-gomez JL, Sepulveda-amor J, Garcia-garcia MD, et al. (2002). A randomized trial demonstrating successful boosting responses following simultaneous aerosols of measles and rubella (mr) vaccines in school age children. Vaccine 20:2790-95.
    • (2002) Vaccine , vol.20 , pp. 2790-3295
    • Valdespino-Gomez, J.L.1    Sepulveda-Amor, J.2    Garcia-Garcia, M.D.3
  • 120
    • 0032734092 scopus 로고    scopus 로고
    • Formulation and physical characterization of large porous particles for inhalation
    • Vanbever R, Mintzes JD, Wang J, et al. (1999). Formulation and physical characterization of large porous particles for inhalation. Pharmaceut Res 16:1735-42.
    • (1999) Pharmaceut Res , vol.16 , pp. 1735-2142
    • Vanbever, R.1    Mintzes, J.D.2    Wang, J.3
  • 121
    • 1842479077 scopus 로고    scopus 로고
    • Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)- camptothecin in patients with advanced pulmonary malignancies
    • Verschraegen CF, Gilbert BE, Loyer E, et al. (2004). Clinical evaluation of the delivery and safety of aerosolized liposomal 9-nitro-20(s)- camptothecin in patients with advanced pulmonary malignancies. Clin Canc Res 10:2319-26.
    • (2004) Clin Canc Res , vol.10 , pp. 2319-3226
    • Verschraegen, C.F.1    Gilbert, B.E.2    Loyer, E.3
  • 123
  • 124
    • 0028011062 scopus 로고
    • Operating characteristics of 18 different continuous-flow jet nebulizers with beclomethasone dipropionate liposome aerosol
    • Waldrep JC, Keyhani K, Black M, Knight V. (1994). Operating characteristics of 18 different continuous-flow jet nebulizers with beclomethasone dipropionate liposome aerosol. Chest 105:106-10. (Pubitemid 24029086)
    • (1994) Chest , vol.105 , Issue.1 , pp. 106-110
    • Waldrep, J.C.1    Keyhani, K.2    Black, M.3    Knight, V.4
  • 125
    • 67549135653 scopus 로고    scopus 로고
    • A gamma scintigraphy study to investigate lung deposition and clearance of inhaled amikacin-loaded liposomes in healthy male volunteers
    • Weers J, Metzheiser B, Taylor G, et al. (2009). A gamma scintigraphy study to investigate lung deposition and clearance of inhaled amikacin-loaded liposomes in healthy male volunteers. J Aerosol Med Pulmon Drug Deliv 22:131-38.
    • (2009) J Aerosol Med Pulmon Drug Deliv , vol.22 , pp. 131-138
    • Weers, J.1    Metzheiser, B.2    Taylor, G.3
  • 127
    • 70350070857 scopus 로고    scopus 로고
    • Coaxial electrohydrodynamic spraying: A novel one-step technique to prepare oligodeoxynucleotide encapsulated lipoplex nanoparticles
    • Wu Y, Yu B, Jackson A, et al. (2009). Coaxial electrohydrodynamic spraying: a novel one-step technique to prepare oligodeoxynucleotide encapsulated lipoplex nanoparticles. Mol Pharmaceut 6:1371-79.
    • (2009) Mol Pharmaceut , vol.6 , pp. 1371-2179
    • Wu, Y.1    Yu, B.2    Jackson, A.3
  • 128
    • 79952937096 scopus 로고    scopus 로고
    • Producing pharmaceutical particles via electrospraying with an emphasis on nano and nano structured particles - A review
    • Yurteri CU, Hartman RPA, Marijnissen JCM. (2010). Producing pharmaceutical particles via electrospraying with an emphasis on nano and nano structured particles-a review. Kona Powd Part J 91-115.
    • (2010) Kona Powd Part J , pp. 91-115
    • Yurteri, C.U.1    Hartman, R.P.A.2    Marijnissen, J.C.M.3
  • 129
    • 85012506583 scopus 로고    scopus 로고
    • Quantification and compensation of nonspecific analyte aggregation in electrospray sampling
    • Zachariah MR, Li MD, Guha S, et al. (2011). Quantification and compensation of nonspecific analyte aggregation in electrospray sampling. Aerosol Sci Technol 45:849-60.
    • (2011) Aerosol Sci Technol , vol.45 , pp. 849-860
    • Zachariah, M.R.1    Li, M.D.2    Guha, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.