Amyloid beta1-42 (Aβ42) up-regulates the expression of sortilin via the p75NTR/RhoA signaling pathway

Journal of Neurochemistry

Volumn 127, Issue 2, 2013, Pages 152-162

  Saadipour, Khalil ^a   Yang, Miao ^a   Lim, Yoon ^a   Georgiou, Kristen ^a   Sun, Ying ^a   Keating, Damien ^b   Liu, Jia ^a   Wang, Ye Ran ^a   Gai, Wei Ping ^b   Zhong, Jin Hua ^a   Wang, Yan Jiang ^c   Zhou, Xin Fu ^a  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

A 42; Alzheimer's disease; p75NTR; RhoA signaling pathway; sortilin

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; MESSENGER RNA; NEUROTROPHIN RECEPTOR P75; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SORTILIN; STRESS ACTIVATED PROTEIN KINASE;

AGED; ALZHEIMER DISEASE; AMYLOID BETA PROTEIN[1-42] GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN LEVEL; CASE REPORT; CONTROLLED STUDY; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SORTILIN GENE; TRANSGENIC MOUSE; UPREGULATION;

AΒ42; ALZHEIMER'S DISEASE; P75NTR; RHOA SIGNALING PATHWAY; SORTILIN;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MICE; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PRESENILIN-1; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, NERVE GROWTH FACTOR; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; UP-REGULATION;

MUS; MUS MUSCULUS;

EID: 84885435327     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12383     Document Type: Article

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