p75NTR regulates Aβ deposition by increasing Aβ production but inhibiting Aβ aggregation with its extracellular domain

Journal of Neuroscience

Volumn 31, Issue 6, 2011, Pages 2292-2304

  Wang, Yan Jiang ^a,b   Wang, Xin ^a,c   Lu, Jian Jun ^a   Li, Qiao Xin ^d,e   Gao, Chang Yue ^a,b   Liu, Xiao Hong ^a   Sun, Yin ^a   Yang, Miao ^a   Lim, Yoon ^a   Evin, Genevieve ^d,e   Zhong, Jin Hua ^a   Masters, Colin ^e   Zhou, Xin Fu ^a  

^a FLINDERS UNIVERSITY   (Australia)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c PEKING UNION MEDICAL COLLEGE   (China)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; BETA SECRETASE; BETA SECRETASE 1; GAMMA SECRETASE; INSULINASE; MEMBRANE METALLOENDOPEPTIDASE; NEUROTROPHIN RECEPTOR P75; SYNTHETIC PEPTIDE; AMYLOID PRECURSOR PROTEIN; ASPARTIC PROTEINASE; BACE1 PROTEIN, MOUSE; NERVE GROWTH FACTOR RECEPTOR; PRESENILIN 1; PSEN1 PROTEIN, HUMAN; SECRETASE; TNFRSF16 PROTEIN, MOUSE;

AGING; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN CORTEX; BRAIN HEMORRHAGE; BRAIN LEVEL; COGNITION; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME ACTIVITY; EXON; EXTRACELLULAR SPACE; FEMALE; FOREBRAIN; GENE DELETION; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; INJECTION; MALE; MOUSE; NEOCORTEX; NEURITE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; TRANSGENIC MOUSE; AGE; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL BEHAVIOR; BRAIN; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MAZE TEST; METABOLISM; MUTATION; NERVE CELL; PHYSIOLOGY;

AGE FACTORS; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANALYSIS OF VARIANCE; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BEHAVIOR, ANIMAL; BRAIN; GENE EXPRESSION REGULATION; HUMANS; INSULYSIN; MAZE LEARNING; MICE; MICE, TRANSGENIC; MUTATION; NEPRILYSIN; NEURONS; PRESENILIN-1; RECEPTORS, NERVE GROWTH FACTOR;

EID: 79951538920     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2733-10.2011     Document Type: Article

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