Depletion of HPV16 early genes induces autophagy and senescence in a cervical carcinogenesis model, regardless of viral physical state

Journal of Pathology

Volumn 231, Issue 3, 2013, Pages 354-366

  Hanning, Jennifer E ^a   Saini, Harpreet K ^b   Murray, Matthew J ^a   Caffarel, Maria M ^a   Van Dongen, Stijn ^b   Ward, Dawn ^a   Barker, Emily M ^a   Scarpini, Cinzia G ^a   Groves, Ian J ^a   Stanley, Margaret A ^a   Enright, Anton J ^b   Pett, Mark R ^a   Coleman, Nicholas ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b EUROPEAN BIOINFORMATICS INSTITUTE   (United Kingdom)

Author keywords

autophagy; cervix; HPV16; senescence; squamous cell carcinoma

Indexed keywords

BETA GALACTOSIDASE; PROTEIN P62; SMALL INTERFERING RNA; SOMATOMEDIN BINDING PROTEIN 3; VIRUS DNA;

ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER STAGING; CARCINOGENESIS; CELL SURVIVAL; CONTROLLED STUDY; E6 VIRUS ONCOGENE; E7 VIRUS ONCOGENE; EPISOME; GENE DELETION; GENE EXPRESSION; HUMAN PAPILLOMAVIRUS TYPE 16; IN VITRO STUDY; INNATE IMMUNITY; KERATINOCYTE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; SENESCENCE; TISSUE CULTURE; TUMOR GROWTH; UPREGULATION; UTERINE CERVIX CARCINOMA; VIRUS GENE; VIRUS ONCOGENE; VIRUS TRANSCRIPTION;

AUTOPHAGY; CERVIX; HPV16; SENESCENCE; SQUAMOUS CELL CARCINOMA;

AUTOPHAGY; CELL AGING; CELL LINE, TUMOR; CELL TRANSFORMATION, VIRAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE EXPRESSION REGULATION, VIRAL; HUMAN PAPILLOMAVIRUS 16; HUMANS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRUS E7 PROTEINS; PAPILLOMAVIRUS INFECTIONS; PHENOTYPE; PLASMIDS; REPRESSOR PROTEINS; RNA INTERFERENCE; RNA, MESSENGER; RNA, VIRAL; TIME FACTORS; TRANSFECTION; UTERINE CERVICAL NEOPLASMS; VIRUS INTEGRATION;

EID: 84885391883     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4244     Document Type: Article

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