Lack of correlation between predicted and actual off-target effects of short-interfering RNAs targeting the human papillomavirus type 16 E7 oncogene

British Journal of Cancer

Volumn 108, Issue 2, 2013, Pages 450-460

  Hanning, J E ^a   Saini, H K ^b   Murray, M J ^a   Van Dongen, S ^b   Davis, M P A ^b   Barker, E M ^a   Ward, D M ^a   Scarpini, C G ^a   Enright, A J ^b   Pett, M R ^a   Coleman, N ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b EUROPEAN BIOINFORMATICS INSTITUTE   (United Kingdom)

Author keywords

E7; HPV16; Off target effects; siRNA; Sylamer

Indexed keywords

MESSENGER RNA; SMALL INTERFERING RNA;

ALGORITHM; ARTICLE; CELL TYPE; CONTROLLED STUDY; FEMALE; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; IN VIVO STUDY; INNATE IMMUNITY; ONCOGENE; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS EPITHELIUM; UPREGULATION; WESTERN BLOTTING;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CERVIX UTERI; EPITHELIAL CELLS; FEMALE; HUMAN PAPILLOMAVIRUS 16; HUMANS; PAPILLOMAVIRUS E7 PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SKIN; UTERINE CERVICAL NEOPLASMS;

EID: 84873569477     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.564     Document Type: Article

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