Expression of a viral oncoprotein in normal human epithelial cells triggers an autophagy-related process: Is autophagy an "Achilles' heel" of human cancers?

Autophagy

Volumn 5, Issue 4, 2009, Pages 578-579

  Zhou, Xiaobo ^a   Spangle, Jennifer M ^a,b   Münger, Karl ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Autophagy; Cervical cancer; HPV16 E6 E7 oncoproteins; Metabolic stress; mTOR; p53; Trophic sentinel pathway

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; ONCOPROTEIN; PROTEIN E6; PROTEIN E7; PROTEIN P53; VIRUS PROTEIN;

ARTICLE; AUTOPHAGY; CANCER INHIBITION; CANCER THERAPY; CELL DEATH; CELL METABOLISM; CELL PROLIFERATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; PROTEIN EXPRESSION; RETINOBLASTOMA; SIGNAL TRANSDUCTION; WART VIRUS;

HUMAN PAPILLOMAVIRUS TYPE 16;

EID: 66349105106     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.5.4.8367     Document Type: Article

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