Properties of Slo1 K+ channels with and without the gating ring

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 41, 2013, Pages 16657-16662

  Budelli, Gonzalo ^a   Geng, Yanyan ^b   Butler, Alice ^a   Magleby, Karl L ^b   Salkoff, Lawrence ^a,c  

^a Department of Anatomy and Neurobiology ^*  (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

1 subunit; BK channel; Iberiotoxin; Kv1.4; Tetraethylammonium

Indexed keywords

AMINO ACID; CALCIUM ION; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; MAGNESIUM; POTASSIUM CHANNEL; SLO1 CHANNEL; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; XENOPUS;

Β1 SUBUNIT; BK CHANNEL; IBERIOTOXIN; KV1.4; TETRAETHYLAMMONIUM;

ANIMALS; CALCIUM; HUMANS; ION CHANNEL GATING; KINETICS; KV1.4 POTASSIUM CHANNEL; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; MAGNESIUM; MICE; MUTAGENESIS, SITE-DIRECTED; OLIGONUCLEOTIDES; OOCYTES; PATCH-CLAMP TECHNIQUES; PEPTIDES; TETRAETHYLAMMONIUM; XENOPUS;

EID: 84885361688     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1313433110     Document Type: Article

References (48)

1. Nelson MT, et al. (1995) Relaxation of arterial smooth muscle by calcium sparks. Science 270(5236):633-637.
2. Brenner R, et al. (2000) Vasoregulation by the beta1 subunit of the calcium-activated potassium channel. Nature 407(6806):870-876.
3. Robitaille R, Garcia ML, Kaczorowski GJ, Charlton MP (1993) Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release. Neuron 11(4):645-655.
4. Montgomery JR, Meredith AL (2012) Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability. Proc Natl Acad Sci USA 109(46): 18997-19002.
5. Fettiplace R, Fuchs PA (1999) Mechanisms of hair cell tuning. Annu Rev Physiol 61:809-834.
6. 2+-dependent K+ channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells. J Physiol 521(1)1:135-146.
7. Marty A (1981) Ca-dependent K channels with large unitary conductance in chromaffin cell membranes. Nature 291(5815):497-500.
8. 2+-activated K+ currents in rat muscle cell culture. Nature 293(5832):471-474.
9. 2+-dependent K+ channel from transverse tubule membranes isolated from rabbit skeletal muscle. Proc Natl Acad Sci USA 79(3):805-809.
10. Hille B (2001) Ion Channels of Excitable Membranes (Sinauer Associates, Inc., Sunderland, MA).
11. Atkinson NS, Robertson GA, Ganetzky B (1991) A component of calcium-activated potassium channels encoded by the Drosophila slo locus. Science 253(5019):551-555.
12. Butler A, Tsunoda S, McCobb DP, Wei A, Salkoff L (1993) mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Science 261(5118):221-224.
13. Schreiber M, Salkoff L (1997) A novel calcium-sensing domain in the BK channel. Biophys J 73(3):1355-1363.
14. Xia XM, Zeng X, Lingle CJ (2002) Multiple regulatory sites in large-conductance calcium-activated potassium channels. Nature 418(6900):880-884.
15. Shi J, et al. (2002) Mechanism of magnesium activation of calcium-activated potassium channels. Nature 418(6900):876-880.
16. 2+ and H+ sensitivity in the SLO1 BK channel conferred by the RCK1 domain. Nat Struct Mol Biol 15(4):403-410.
17. Tang XD, et al. (2003) Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels. Nature 425(6957):531-535.
18. 2+ sensor confers carbon monoxide sensitivity to Slo1 BK channels. Proc Natl Acad Sci USA 105(10): 4039-4043.
19. Schubert R, Nelson MT (2001) Protein kinases: Tuners of the BKCa channel in smooth muscle. Trends Pharmacol Sci 22(10):505-512.
20. 2+-dependent K+ channels. Biochem Biophys Res Commun 342(4):1389-1395.
21. 2+-activated potassium channel. Neuron 42(5):745-756.
22. Lee US, Cui J (2010) BK channel activation: Structural and functional insights. Trends Neurosci 33(9):415-423.
23. 2+-activated K+ channel. Nature 481(7379): 94-97.
24. Schmalhofer WA, et al. (2005) Role of the C-terminus of the high-conductance calcium-activated potassium channel in channel structure and function. Biochemistry 44(30):10135-10144.
25. Li D, Takimoto K, Levitan ES (2000) Surface expression of Kv1 channels is governed by a C-terminal motif. J Biol Chem 275(16):11597-11602.
26. Quirk JC, Reinhart PH (2001) Identification of a novel tetramerization domain in large conductance K(ca) channels. Neuron 32(1):13-23.
27. Li W, Aldrich RW (2006) State-dependent block of BK channels by synthesized shaker ball peptides. J Gen Physiol 128(4):423-441.
28. Díaz L, et al. (1998) Role of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channel. J Biol Chem 273(49):32430-32436.
29. Ma Z, Lou XJ, Horrigan FT (2006) Role of charged residues in the S1-S4 voltage sensor of BK channels. J Gen Physiol 127(3):309-328.
30. Savalli N, Pantazis A, Yusifov T, Sigg D, Olcese R (2012) The contribution of RCK domains to human BK channel allosteric activation. J Biol Chem 287(26):21741-21750.
31. 2+ signals by Slo1 BK channels. Physiology (Bethesda) 28(3):172-189.
32. Brelidze TI, Niu X, Magleby KL (2003) A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification. Proc Natl Acad Sci USA 100(15):9017-9022.
33. Nimigean CM, Chappie JS, Miller C (2003) Electrostatic tuning of ion conductance in potassium channels. Biochemistry 42(31):9263-9268.
34. Galvez A, et al. (1990) Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus. J Biol Chem 265(19):11083-11090.
35. Blatz AL, Magleby KL (1984) Ion conductance and selectivity of single calcium-activated potassium channels in cultured rat muscle. J Gen Physiol 84(1):1-23.
36. 2+-activated K+ channel incorporated into planar lipid bilayers. Biophys J 45(1): 73-76.
37. Contreras GF, Neely A, Alvarez O, Gonzalez C, Latorre R (2012) Modulation of BK channel voltage gating by different auxiliary β subunits. Proc Natl Acad Sci USA 109(46):18991-18996.
38. Morrow JP, et al. (2006) Defining the BK channel domains required for beta1-subunit modulation. Proc Natl Acad Sci USA 103(13):5096-5101.
39. Liu G, et al. (2010) Location of modulatory beta subunits in BK potassium channels. J Gen Physiol 135(5):449-459.
40. 2+ binding to the BKCa channel. J Gen Physiol 133(2):139-150.
41. Li Y, Berke I, Chen L, Jiang Y (2007) Gating and inward rectifying properties of the MthK K+ channel with and without the gating ring. J Gen Physiol 129(2):109-120.
42. 2+-activation apparatus at 3.0 A resolution. Science 329(5988):182-186.
43. Jiang Y, et al. (2002) Crystal structure and mechanism of a calcium-gated potassium channel. Nature 417(6888):515-522.
44. Magleby KL (2003) Gating mechanism of BK (Slo1) channels: So near, yet so far. J Gen Physiol 121(2):81-96.
45. Horrigan FT (2012) Perspectives on: Conformational coupling in ion channels: Conformational coupling in BK potassium channels. J Gen Physiol 140(6):625-634.
46. 2+. J Gen Physiol 114(2):277-304.
47. Zhang Y, Niu X, Brelidze TI, Magleby KL (2006) Ring of negative charge in BK channels facilitates block by intracellular Mg2+ and polyamines through electrostatics. J Gen Physiol 128(2):185-202.
48. 2+-activated potassium channels by retaining the gating in the bursting states. J Gen Physiol 113(3):425-440.