State-dependent block of BK channels by synthesized shaker ball peptides

Journal of General Physiology

Volumn 128, Issue 4, 2006, Pages 423-441

  Li, Weiyan ^a   Aldrich, Richard W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; METHIONYLALANYLALANYLVALYLALANYLLEUCYLTYROSYLGLYCYL LEUCYLGLYCYLGLUTAMYLASPARTYLARGINYLGLUTAMINYLHISTIDYLARGINYLLYSYLLYSYLGLUTAMINE; PEPTIDE; QUATERNARY AMMONIUM DERIVATIVE; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CYTOPLASM; GENE MUTATION; KINETICS; PROTEIN INTERACTION; SEQUENCE HOMOLOGY;

ANIMALS; CALCIUM; FEMALE; ION CHANNEL GATING; KINETICS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MICE; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PEPTIDE FRAGMENTS; PEPTIDES; POTASSIUM CHANNEL BLOCKERS; QUATERNARY AMMONIUM COMPOUNDS; RNA, COMPLEMENTARY; SHAKER SUPERFAMILY OF POTASSIUM CHANNELS; XENOPUS LAEVIS;

EID: 33748997977     PISSN: 00221295     EISSN: 00221295     Source Type: Journal    
DOI: 10.1085/jgp.200609521     Document Type: Article

References (61)

1. Armstrong, C.M., and B. Hille. 1972. The inner quaternary ammonium ion receptor in potassium channels of the node of Ranvier. J. Gen. Physiol. 59:388-400.
2. Bers, D.M. 1982. A simple method for the accurate determination of free [Ca] in Ca-EGTA solutions. Am. J. Physiol. 242:C404-C408.
3. Brelidze, T.I., and K.L. Magleby. 2005. Probing the geometry of the inner vestibule of BK channels with sugars. J. Gen. Physiol. 126:105-121.
4. Brelidze, T.I., X. Niu, and K.L. Magleby. 2003. A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification. Proc. Natl. Acad. Sci. USA. 100:9017-9022.
5. + channels. J. Neurosci. 22:6499-6506.
6. Butler, A., S. Tsunoda, D.P. McCobb, A. Wei, and L. Salkoff. 1993. mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Science. 261:221-224.
7. + channels. Proc. Natl. Acad. Sci. USA. 88:5092-5095.
8. Choi, K.L., C. Mossman, J. Aube, and G. Yellen. 1993. The internal quaternary ammonium receptor site of Shaker potassium channels. Neuron. 10:533-541.
9. Clay, J.R. 1995. Quaternary ammonium ion blockade of IK in nerve axons revisited. Open channel block vs. state independent block. J. Membr. Biol. 147:23-34.
10. + channels. J. Gen. Physiol. 109:633-646.
11. + channels. J. Gen. Physiol. 109:647-673.
12. + channel and its structural implications. Nature. 403:321-325.
13. + channel. Neuron. 32:649-656.
14. + channel behaves like an open-channel blocker. Neuron. 7:743-753.
15. + (hslo) channel from smooth muscle. J. Gen. Physiol. 107:399-407.
16. Ding, S., and R. Horn. 2002. Tail end of the s6 segment: role in permeation in shaker potassium channels. J. Gen. Physiol. 120:87-97.
17. Ding, S., and R. Horn. 2003. Effect of S6 tail mutations on charge movement in Shaker potassium channels. Biophys. J. 84:295-305.
18. + conduction and selectivity. Science. 280:69-77.
19. Ferguson, W.B., O.B. McManus, and K.L. Magleby. 1993. Opening and closing transitions for BK channels often occur in two steps via sojourns through a brief lifetime subconductance state. Biophys. J. 65:702-714.
20. Flynn, G.E., and W.N. Zagotta. 2001. Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels. Neuron. 30:689-698.
21. + channels. Neuron. 9:229-236.
22. + channel. J. Gen. Physiol. 119:521-532.
23. Hamill, O.P., A. Marty, E. Neher, B. Sakmann, and F.J. Sigworth. 1981. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 391:85-100.
24. + channels: evidence for a trap door mechanism of activation gating. J. Gen. Physiol. 109:527-535.
25. 2+. J. Gen. Physiol. 114:277-304.
26. + channel. Nature. 353:86-90.
27. Jiang, Y., A. Lee, J. Chen, M. Cadene, B.T. Chait, and R. MacKinnon. 2002a. Crystal structure and mechanism of a calcium-gated potassium channel. Nature. 417:515-522.
28. Jiang, Y., A. Lee, J. Chen, M. Cadene, B.T. Chait, and R. MacKinnon. 2002b. The open pore conformation of potassium channels. Nature. 417:523-526.
29. + channel. Nature. 423:33-41.
30. Kiss, L., J. LoTurco, and S.J. Korn. 1999. Contribution of the selectivity filter to inactivation in potassium channels. Biophys. J. 76:253-263.
31. Korn, S.J., and J.G. Trapani. 2005. Potassium channels. IEEE Trans Nanobioscience. 4:21-33.
32. Kramer, R.H., E. Goulding, and S.A. Siegelbaum. 1994. Potassium channel inactivation peptide blocks cyclic nucleotide-gated channels by binding to the conserved pore domain. Neuron. 12:655-662.
33. Kuo, A., J.M. Gulbis, J.F. Antcliff, T. Rahman, E.D. Lowe, J. Zimmer, J. Cuthbertson, F.M. Ashcroft, T. Ezaki, and D.A. Doyle. 2003. Crystal structure of the potassium channel KirBac1.1 in the closed state. Science. 300:1922-1926.
34. Li, W., and R.W. Aldrich. 2004. Unique inner pore properties of BK channels revealed by quaternary ammonium block. J. Gen. Physiol. 124:43-57.
35. + channel. Neuron. 19:175-184.
36. + channel during gating. Neuron. 16:859-867.
37. + channel. Science. 309:897-903.
38. Lopez-Barneo, J., T. Hoshi, S.H. Heinemann, and R.W. Aldrich. 1993. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels. 1:61-71.
39. Murrell-Lagnado, R.D., and R.W. Aldrich. 1993a. Energetics of Shaker K channels block by inactivation peptides. J. Gen. Physiol. 102:977-1003.
40. Murrell-Lagnado, R.D., and R.W. Aldrich. 1993b. Interactions of amino terminal domains of Shaker K channels with a pore blocking site studied with synthetic peptides. J. Gen. Physiol. 102:949-975.
41. + channels. Biophys. J. 71:220-226.
42. Nimigean, C.M., J.S. Chappie, and C. Miller. 2003. Electrostatic tuning of ion conductance in potassium channels. Biochemistry. 42:9263-9268.
43. + channels. Neuron. 37:953-962.
44. Proks, P., J.F. Antcliff, and F.M. Ashcroft. 2003. The ligand-sensitive gate of a potassium channel lies close to the selectivity filter. EMBO Rep. 4:70-75.
45. Qin, F., A. Auerbach, and F. Sachs. 1996. Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events. Biophys. J. 70:264-280.
46. + channel, expressed in oocytes. Biophys. J. 70:2640-2651.
47. Solaro, C.R., J.P. Ding, Z.W. Li, and C.J. Lingle. 1997. The cytosolic inactivation domains of BKi channels in rat chromaffin cells do not behave like simple, open-channel blockers. Biophys. J. 73:819-830.
48. + channel. Biochemistry. 33:7220-7228.
49. + channel by Shaker B inactivating "ball" peptide. Neuron. 9:237-245.
50. + channels: a transmembrane β-subunit homolog. Proc. Natl. Acad. Sci. USA. 96:4137-4142.
51. + channels defined by high-affinity metal bridges. Nature. 428:864-868.
52. Wilkens, C.M., and R.W. Aldrich. 2006. State independent block of BK channels by intracellular quaternary ammonium. J. Gen. Physiol. 128:347-364.
53. 2+- and voltage-dependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells. J. Neurosci. 19:5255-5264.
54. 2 terminus of the β2 auxiliary subunit: an essential role of a terminal peptide segment of three hydrophobic residues. J. Gen. Physiol. 121:125-148.
55. + channels. Nat. Neurosci. 6:811-818.
56. Yeh, J.Z., and C.M. Armstrong. 1978. Immobilisation of gating charge by a substance that simulates inactivation. Nature. 273:387-389.
57. + channel allows inactivation to be modulated by metal binding. Biophys. J. 66:1068-1075.
58. Zagotta, W.N., T. Hoshi, and R.W. Aldrich. 1990. Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB. Science. 250:568-571.
59. Zei, P.C., E.M. Ogielska, T. Hoshi, and R.W. Aldrich. 1999. Effects on ion permeation with hydrophobic substitutions at a residue in Shaker S6 that interacts with a signature sequence amino acid. Ann. NY Acad. Sci. 868:458-464.
60. Zheng, J., and F.J. Sigworth. 1998. Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels. J. Gen. Physiol. 112:457-474.
61. Zhou, M., J.H. Morais-Cabral, S. Mann, and R. MacKinnon. 2001. Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors. Nature. 411:657-661.