Role of the C-terminus of the high-conductance calcium-activated potassium channel in channel structure and function

Biochemistry

Volumn 44, Issue 30, 2005, Pages 10135-10144

  Schmalhofer, William A ^a   Sanchez, Manuel ^a   Dai, Ge ^a   Dewan, Ashvin ^a   Secades, Lorena ^a   Hanner, Markus ^a   Knaus, Hans Guenther ^b   McManus, Owen B ^a   Kohler, Martin ^a   Kaczorowski, Gregory J ^a   Garcia, Maria L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Institute for Biochemical Pharmacology   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ENGINEERING; BIOSYNTHESIS; CALCIUM; ELECTROPHYSIOLOGY; PHYSIOLOGY;

CELL PHYSIOLOGY; CHANNEL STRUCTURES; TETRAMERIZATION; TRAFFICKING;

POTASSIUM;

CALCIUM ACTIVATED POTASSIUM CHANNEL; IBERIOTOXIN; PAXILLIN; TETRAMER;

ARTICLE; BETA CHAIN; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CELL COMPARTMENTALIZATION; CELL SURFACE; CHANNEL GATING; CONDUCTANCE; ELECTROPHYSIOLOGY; GENE EXPRESSION; PRIORITY JOURNAL; PROTEIN STRUCTURE;

ASPARTIC ACID; CELL LINE; CELL MEMBRANE; HUMANS; IODINE RADIOISOTOPES; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MONOIODOTYROSINE; PEPTIDE FRAGMENTS; PEPTIDES; PHENYLALANINE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; PROTEIN TRANSPORT; SCORPION VENOMS; TRANSFECTION; TYROSINE;

EID: 23044466682     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050527u     Document Type: Article

References (37)

1. + channels as therapeutic drug targets, Pharmacol. Ther. 94, 157-182.
2. Bendahhou, S., Donaldson, M. R., Plaster, N. M., Tristani Firouzi, M., Fu, Y. H., and Ptacek, L. J. (2003) Defective potassium channel Kir2.1 trafficking underlies Andersen-Tawil syndrome, J. Biol. Chem. 278, 51779-51785.
3. Manganas, L. N., Akhtar, S., Antonucci, D. E., Campomanes, C. R., Dolly, J. O., and Trimmer, J. S. (2001) Episodic ataxia type-1 mutations in the Kv1.1 potassium channel display distinct folding and intracellular trafficking properties, J. Biol Chem. 276, 49427-49434.
4. Huopio, H., Shyng, S. L., Otonkoski, T., and Nichols, C. G. (2002) K(ATP) channels and insulin secretion disorders, Am. J. Physiol. 283, E207-E216.
5. Thomas, D., Kiehn, J., Katus, H. A., and Karle, C. A. (2003) Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): Molecular mechanisms and restoration of intracellular protein processing, Cardiovasc. Res. 60, 235-241.
6. Orio, P., Rojas, P., Ferreira, G., and Latorre, R. (2002) New disguises for an old channel: MaxiK channel β-subunits, News Physiol. Sci. 17, 156-161.
7. McManus, O. B., Helms, L. M., Pallanck, L., Ganetzky, B., Swanson, R., and Leonard, R. J. (1995) Functional role of the β subunit of high conductance calcium-activated potassium channels, Neuron 14, 645-650.
8. Hanner, M., Schmalhofer, W. A., Munujos, P., Knaus, H. G., Kaczorowski, G. J., and Garcia, M. L. (1997) The β subunit of the high-conductance calcium-activated potassium channel contributes to the high-affinity receptor for charybdotoxin, Proc. Natl. Acad. Sci. U.S.A. 94, 2853-2858.
9. + channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N terminus, and an intracellular (S9-S10) C terminus. Proc. Natl. Acad. Sci. U.S.A. 94, 14066-14071.
10. Jiang, Y., Lee, A., Chen, J., Cadene, M., Chait, B. T., and MacKinnon, R. (2002) Crystal structure and mechanism of a calcium-gated potassium channel, Nature 417, 515-522.
11. + channel and demonstration of its presence in the human BK channel, Neuron 29, 593-601.
12. 2+-activated potassium channel, Neuron 42, 745-756.
13. ca channels, Neuron 32, 13-23.
14. + channel α-subunit in Madin-Darby canine kidney cells is independent of N-glycosylation, Proc. Natl. Acad. Sci. U.S.A. 97, 13114-13119.
15. + (MaxiK) channel is necessary for its cell surface expression, J. Biol. Chem. 278, 2713-2722.
16. Kwon, S.-H., and Guggino, W. B. (2004) Multiple sequences in the C terminus of MaxiK channels are involved in expression, movement to the cell surface, and apical localization, Proc. Natl. Acad. Sci. U.S.A. 101, 15237-15242.
17. Piskorowski, R., and Aldrich, R. W. (2002) Calcium activation of BK(Ca) potassium channels lacking the calcium bowl and RCK domains, Nature 420, 499-502.
18. 125I]Iberiotoxin-D19Y/Y36F, the first selective, high specific activity radioligand for high-conductance calcium-activated potassium channels, Biochemistry 36, 1943-1952.
19. + channels, Bioconjugate Chem. 13, 416-425.
20. Wallner, M., Meera, P., Ottolia, M., Kaczorowski, G. J., Latorre, R., Garcia, M. L., Stefani, E., and Toro, L. (1995) Characterization of and modulation by a β-subunit of a human maxi KCa channel cloned from myometrium, Recept. Channels 3, 185-199.
21. V1.3 potassium channel: Characterization of the binding domain by site-directed mutagenesis, Biochemistry 40, 11687-11697.
22. Giangiacomo, K. M., Fremont, V., Mullmann, T. J., Hanner, M., Cox, R. H., and Garcia, M. L. (2000) Interaction of charybdotoxin S10A with single maxi-K channels: Kinetics of blockade depend on the presence of the β1 subunit, Biochemistry 39, 6115-6122.
23. + channel, J. Biol. Chem. 270, 22434-22439.
24. Hamill, O. P., Marty, A., Neher, E., Sakmann, B., and Sigworth, F. J. (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches, Pfluegers Arch. 391, 85-100.
25. Xia, X. M., Zeng, X., and Lingle, C. J. (2002) Multiple regulatory sites in large-conductance calcium-activated potassium channels, Nature 418, 880-884.
26. Xia, X. M., Zhang, X., and Lingle, C. J. (2004) Ligand-dependent activation of Slo family channels is defined by interchangeable cytosolic domains, J. Neurosci. 24, 5585-5591.
27. Wei, A., Solaro, C., Lingle, C., and Salkoff, L. (1994) Calcium sensitivity of BK-type KCa channels determined by a separable domain, Neuron 13, 671-681.
28. Schreiber, M., Yuan, A., and Salkoff, L. (1999) Transplantable sites confer calcium sensitivity to BK channels, Nat. Neurosci. 2, 416-421.
29. MacKinnon, R. (1991) Determination of the subunit stoichiometry of a voltage-activated potassium channel, Nature 350, 232-235.
30. Knaus, H. G., McManus, O. B., Lee, S. H., Schmalhofer, W. A., Garcia Calvo, M., Helms, L. M., Sanchez, M., Giangiacomo, K., Reuben, J. P., Smith, A. B., III, et al. (1994) Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels, Biochemistry 33, 5819-5828.
31. Tanaka, Y., Koike, K., Alioua, A., Shigenobu, K., Stefani, E., and Toro, L. (2004) β1-subunit of MaxiK channel in smooth muscle: A key molecule which tunes muscle mechanical activity. J. Pharmacol. Sci. 94, 339-347.
32. Teasdale, R. D., and Jackson, M. R. (1996) Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the Golgi apparatus, Annu. Rev. Cell Dev. Biol. 12, 27-54.
33. + channel splice variant, Proc. Natl. Acad. Sci. U.S.A. 101, 10072-10077.
34. Munujos, P., Knaus, H. G., Kaczorowski, G. J., and Garcia, M. L. (1995) Cross-linking of charybdotoxin to high-conductance calcium-activated potassium channels: Identification of the covalently modified toxin residue, Biochemistry 34, 10771-10776.
35. Garcia Calvo, M., Knaus, H. G., McManus, O. B., Giangiacomo, K. M., Kaczorowski, G. J., and Garcia, M. L. (1994) Purification and reconstitution of the high-conductance, calcium-activated potassium channel from tracheal smooth muscle, J. Biol. Chem. 269, 676-682.
36. + channel resistant to charybdotoxin and iberiotoxin. Proc. Natl. Acad. Sci. U.S.A. 97, 5562-5567.
37. + channel in mouse myometrium with pregnancy, J. Biol. Chem. 278, 45311-45317.