Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 46, 2012, Pages 18997-19002

  Montgomery, Jenna R ^a   Meredith, Andrea L ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Action potential; BK agonist; Kcnma1; Patch clamp; Slo1

Indexed keywords

CALCIUM; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELL TYPE; CIRCADIAN RHYTHM; GAIN OF FUNCTION MUTATION; GENE ACTIVATION; GENE EXPRESSION; GENE INSERTION; HUMAN; HUMAN CELL; HYPOTHALAMUS; IN VIVO STUDY; ION CURRENT; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; SUPRACHIASMATIC NUCLEUS; WILD TYPE;

ACTION POTENTIALS; AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; DISEASE MODELS, ANIMAL; HEK293 CELLS; HUMANS; ION CHANNEL GATING; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MENTAL DISORDERS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; NEURONS; PERIOD CIRCADIAN PROTEINS; SUPRACHIASMATIC NUCLEUS;

MUS MUSCULUS;

EID: 84869222328     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1205573109     Document Type: Article

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