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Volumn 64, Issue 2, 2013, Pages 204-210

TLR2-activated B cells are phenotypically similar to the abnormal circulating B cells seen preceding the diagnosis of AIDS-related NHL diagnosis

Author keywords

Activation induced cytidine deaminase; AIDS lymphoma; HIV; Non Hodgkin lymphoma; Phenotype; Toll like receptor

Indexed keywords

TOLL LIKE RECEPTOR 2;

EID: 84885314839     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0b013e31829d4d50     Document Type: Article
Times cited : (10)

References (42)
  • 1
    • 0033179409 scopus 로고    scopus 로고
    • Kaposi's sarcoma and non-Hodgkin's lymphoma incidence trends in AIDS Clinical Trial Group study participants
    • Huang J, et al. Kaposi's sarcoma and non-Hodgkin's lymphoma incidence trends in AIDS Clinical Trial Group study participants. J Acquir Immune Defic Syndr. 1999;21(suppl 1):S31-S33.
    • (1999) J Acquir Immune Defic Syndr , vol.21 , Issue.SUPPL. 1
    • Huang, J.1
  • 2
    • 0021713481 scopus 로고
    • Non-Hodgkin's lymphoma in 90 homosexual men. Relation to generalized lymphadenopathy and the acquired immunodeficiency syndrome
    • Ziegler JL, Beckstead JA, Volberding PA, et al. Non-Hodgkin's lymphoma in 90 homosexual men. Relation to generalized lymphadenopathy and the acquired immunodeficiency syndrome. N Engl J Med. 1984;311: 565-570.
    • (1984) N Engl J Med , vol.311 , pp. 565-570
    • Ziegler, J.L.1    Beckstead, J.A.2    Volberding, P.A.3
  • 3
    • 27244431778 scopus 로고    scopus 로고
    • AIDS-related lymphomas: From pathogenesis to pathology
    • Carbone A, Gloghini A. AIDS-related lymphomas: from pathogenesis to pathology. Br J Haematol. 2005;130: 662-670.
    • (2005) Br J Haematol , vol.130 , pp. 662-670
    • Carbone, A.1    Gloghini, A.2
  • 5
    • 43949097900 scopus 로고    scopus 로고
    • Cancer risk in people infected with human immunodeficiency virus in the United States
    • Engels EA, Biggar RJ, Hall HI, et al. Cancer risk in people infected with human immunodeficiency virus in the United States. Int J Cancer. 2008; 123: 187-194.
    • (2008) Int J Cancer , vol.123 , pp. 187-194
    • Engels, E.A.1    Biggar, R.J.2    Hall, H.I.3
  • 6
    • 78649448135 scopus 로고    scopus 로고
    • Cancer incidence in the multicenter AIDS Cohort Study before and during the HAART era: 1984 to 2007
    • Seaberg EC, Wiley D, Martinez-Maza O, et al. Cancer incidence in the multicenter AIDS Cohort Study before and during the HAART era: 1984 to 2007. Cancer. 2010;116: 5507-5516.
    • (2010) Cancer , vol.116 , pp. 5507-5516
    • Seaberg, E.C.1    Wiley, D.2    Martinez-Maza, O.3
  • 7
    • 0033870774 scopus 로고    scopus 로고
    • The molecular basis of acquired immunodeficiency syndrome-related lymphomagenesis
    • Gaidano G, Capello D, Carbone A. The molecular basis of acquired immunodeficiency syndrome-related lymphomagenesis. Semin Oncol. 2000;27: 431-441.
    • (2000) Semin Oncol , vol.27 , pp. 431-441
    • Gaidano, G.1    Capello, D.2    Carbone, A.3
  • 8
    • 78549253786 scopus 로고    scopus 로고
    • HIV-associated immune dysfunction and viral infection: Role in the pathogenesis of AIDS-related lymphoma
    • Epeldegui M, Vendrame E, Martinez-Maza O. HIV-associated immune dysfunction and viral infection: role in the pathogenesis of AIDS-related lymphoma. Immunol Res. 2010;48: 72-83.
    • (2010) Immunol Res , vol.48 , pp. 72-83
    • Epeldegui, M.1    Vendrame, E.2    Martinez-Maza, O.3
  • 9
    • 33746871449 scopus 로고    scopus 로고
    • Pathogenesis of AIDS lymphoma: Role of oncogenic viruses and B cell activation-associated molecular lesions
    • Epeldegui M, Widney DP, Martinez-Maza O. Pathogenesis of AIDS lymphoma: role of oncogenic viruses and B cell activation-associated molecular lesions. Curr Opin Oncol. 2006;18: 444-448.
    • (2006) Curr Opin Oncol , vol.18 , pp. 444-448
    • Epeldegui, M.1    Widney, D.P.2    Martinez-Maza, O.3
  • 10
    • 0036736539 scopus 로고    scopus 로고
    • B-cell activation and lymphoma in patients with HIV
    • Martinez-Maza O, Breen EC. B-cell activation and lymphoma in patients with HIV. Curr Opin Oncol. 2002;14: 528-532.
    • (2002) Curr Opin Oncol , vol.14 , pp. 528-532
    • Martinez-Maza, O.1    Breen, E.C.2
  • 11
    • 77955362036 scopus 로고    scopus 로고
    • CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes
    • Epeldegui M, Thapa DR, De la Cruz J, et al. CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes. PLoS One. 2010;5:e11448.
    • (2010) PLoS One , vol.5
    • Epeldegui, M.1    Thapa, D.R.2    De La Cruz, J.3
  • 12
    • 34249824611 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1-associated CD40 ligand transactivates B lymphocytes and promotes infection of CD4+ T cells
    • Martin G, Roy J, Barat C, et al. Human immunodeficiency virus type 1-associated CD40 ligand transactivates B lymphocytes and promotes infection of CD4+ T cells. J Virol. 2007;81: 5872-5881.
    • (2007) J Virol , vol.81 , pp. 5872-5881
    • Martin, G.1    Roy, J.2    Barat, C.3
  • 13
    • 79551707880 scopus 로고    scopus 로고
    • Acquisition of host-derived CD40L by HIV-1 in vivo and its functional consequences in the B-cell compartment
    • Imbeault M, Ouellet M, Giguere K, et al. Acquisition of host-derived CD40L by HIV-1 in vivo and its functional consequences in the B-cell compartment. J Virol. 2011;85: 2189-2200.
    • (2011) J Virol , vol.85 , pp. 2189-2200
    • Imbeault, M.1    Ouellet, M.2    Giguere, K.3
  • 14
    • 79960102823 scopus 로고    scopus 로고
    • B-cell stimulatory cytokines and markers of immune activation are elevated several years prior to the diagnosis of systemic AIDS-associated non-Hodgkin B-cell lymphoma
    • Breen EC, Hussain SK, Magpantay L, et al. B-cell stimulatory cytokines and markers of immune activation are elevated several years prior to the diagnosis of systemic AIDS-associated non-Hodgkin B-cell lymphoma. Cancer Epidemiol Biomarkers Prev. 2011;20: 1303-1314.
    • (2011) Cancer Epidemiol Biomarkers Prev , vol.20 , pp. 1303-1314
    • Breen, E.C.1    Hussain, S.K.2    Magpantay, L.3
  • 15
    • 84885305335 scopus 로고    scopus 로고
    • Toll-like receptor (TLR)-mediated activation of peripheral and gut associated lymphoid tissue (GALT) B cells in HIV infection
    • March 4-10; Seattle, WA
    • Siewe BKA, Kazmi N, Losurdo J, et al. Toll-like receptor (TLR)-mediated activation of peripheral and gut associated lymphoid tissue (GALT) B cells in HIV infection. Presented at: Conference on Retroviruses and Opportunistic Infections (CROI); March 4-10, 2012; Seattle, WA.
    • (2012) Conference on Retroviruses and Opportunistic Infections (CROI)
    • Siewe, B.K.A.1    Kazmi, N.2    Losurdo, J.3
  • 16
    • 0023240958 scopus 로고
    • Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity
    • Martinez-Maza O, Crabb E, Mitsuyasu RT, et al. Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity. J Immunol. 1987;138: 3720-3724.
    • (1987) J Immunol , vol.138 , pp. 3720-3724
    • Martinez-Maza, O.1    Crabb, E.2    Mitsuyasu, R.T.3
  • 17
    • 0036212917 scopus 로고    scopus 로고
    • Molecular mechanism of class switch recombination: Linkage with somatic hypermutation
    • Honjo T, Kinoshita K, Muramatsu M. Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu Rev Immunol. 2002;20: 165-196.
    • (2002) Annu Rev Immunol , vol.20 , pp. 165-196
    • Honjo, T.1    Kinoshita, K.2    Muramatsu, M.3
  • 18
    • 0037881911 scopus 로고    scopus 로고
    • Constitutive expression of AID leads to tumorigenesis
    • Okazaki IM, Hiai H, Kakazu N, et al. Constitutive expression of AID leads to tumorigenesis. J Exp Med. 2003;197: 1173-1181.
    • (2003) J Exp Med , vol.197 , pp. 1173-1181
    • Okazaki, I.M.1    Hiai, H.2    Kakazu, N.3
  • 19
    • 37549068541 scopus 로고    scopus 로고
    • AID is required for germinal center-derived lymphomagenesis
    • Pasqualucci L, Bhagat G, Jankovic M, et al. AID is required for germinal center-derived lymphomagenesis. Nat Genet. 2008;40: 108-112.
    • (2008) Nat Genet , vol.40 , pp. 108-112
    • Pasqualucci, L.1    Bhagat, G.2    Jankovic, M.3
  • 20
    • 37349024988 scopus 로고    scopus 로고
    • Elevated expression of activation induced cytidine deaminase in peripheral blood mononuclear cells precedes AIDS-NHL diagnosis
    • Epeldegui M, Breen EC, Hung YP, et al. Elevated expression of activation induced cytidine deaminase in peripheral blood mononuclear cells precedes AIDS-NHL diagnosis. AIDS. 2007;21: 2265-2270.
    • (2007) AIDS , vol.21 , pp. 2265-2270
    • Epeldegui, M.1    Breen, E.C.2    Hung, Y.P.3
  • 21
    • 79551583111 scopus 로고    scopus 로고
    • Effect of highly active antiretroviral therapy on biomarkers of B-lymphocyte activation and inflammation
    • Regidor DL, Detels R, Breen EC, et al. Effect of highly active antiretroviral therapy on biomarkers of B-lymphocyte activation and inflammation. AIDS. 2011;25: 303-314.
    • (2011) AIDS , vol.25 , pp. 303-314
    • Regidor, D.L.1    Detels, R.2    Breen, E.C.3
  • 22
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 2000; 403: 503-511.
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3
  • 24
    • 84858157707 scopus 로고    scopus 로고
    • The multicenter aids cohort study 1983 to
    • Detels R, Jacobson L, Margolick J, et al. The multicenter AIDS Cohort Study, 1983 to.. Public Health. 2012;126: 196-198.
    • (2012) Public Health , vol.126 , pp. 196-198
    • Detels, R.1    Jacobson, L.2    Margolick, J.3
  • 25
    • 33748789332 scopus 로고    scopus 로고
    • Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutationinducing molecules and in the accrual of oncogene mutations
    • Epeldegui M, Hung YP, McQuay A, et al. Infection of human B cells with Epstein-Barr virus results in the expression of somatic hypermutationinducing molecules and in the accrual of oncogene mutations. Mol Immunol. 2007;44: 934-942.
    • (2007) Mol Immunol , vol.44 , pp. 934-942
    • Epeldegui, M.1    Hung, Y.P.2    McQuay, A.3
  • 26
    • 0036681848 scopus 로고    scopus 로고
    • Absolute level of Epstein-Barr virus DNA in human immunodeficiency virus type 1 infection is not predictive of AIDS-related non-Hodgkin lymphoma
    • Van Baarle D, Wolthers KC, Hovenkamp E, et al. Absolute level of Epstein-Barr virus DNA in human immunodeficiency virus type 1 infection is not predictive of AIDS-related non-Hodgkin lymphoma. J Infect Dis. 2002;186: 405-409.
    • (2002) J Infect Dis , vol.186 , pp. 405-409
    • Van Baarle, D.1    Wolthers, K.C.2    Hovenkamp, E.3
  • 27
    • 63149142646 scopus 로고    scopus 로고
    • B cells in HIV infection and disease
    • Moir S, Fauci AS. B cells in HIV infection and disease. Nat Rev Immunol. 2009;9: 235-245.
    • (2009) Nat Rev Immunol , vol.9 , pp. 235-245
    • Moir, S.1    Fauci, A.S.2
  • 28
    • 0036624881 scopus 로고    scopus 로고
    • B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigenexperienced B lymphocytes
    • Damle RN, Ghiotto F, Valetto A, et al. B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigenexperienced B lymphocytes. Blood. 2002;99: 4087-4093.
    • (2002) Blood , vol.99 , pp. 4087-4093
    • Damle, R.N.1    Ghiotto, F.2    Valetto, A.3
  • 29
    • 0034125061 scopus 로고    scopus 로고
    • CD10 and BCL-6 expression in paraffin sections of normal lymphoid tissue and B-cell lymphomas
    • Dogan A, Bagdi E, Munson P, et al. CD10 and BCL-6 expression in paraffin sections of normal lymphoid tissue and B-cell lymphomas. Am J Surg Pathol. 2000;24: 846-852.
    • (2000) Am J Surg Pathol , vol.24 , pp. 846-852
    • Dogan, A.1    Bagdi, E.2    Munson, P.3
  • 30
    • 0028009982 scopus 로고
    • In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease
    • Munro JM, Freedman AS, Aster JC, et al. In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease. Blood. 1994;83: 793-798.
    • (1994) Blood , vol.83 , pp. 793-798
    • Munro, J.M.1    Freedman, A.S.2    Aster, J.C.3
  • 31
    • 0035760292 scopus 로고    scopus 로고
    • Non-Hodgkin lymphoma in HIV-infected patients in the era of highly active antiretroviral therapy
    • Kirk O, Pedersen C, Cozzi-Lepri A, et al. Non-Hodgkin lymphoma in HIV-infected patients in the era of highly active antiretroviral therapy. Blood. 2001;98: 3406-3412.
    • (2001) Blood , vol.98 , pp. 3406-3412
    • Kirk, O.1    Pedersen, C.2    Cozzi-Lepri, A.3
  • 32
    • 0003248215 scopus 로고    scopus 로고
    • AIDS Across Europe 1994-98: The EuroSIDA study
    • Mocroft A, Katlama C, Johnson AM, et al. AIDS across Europe, 1994- 98: the EuroSIDA study. Lancet. 2000;356: 291-296.
    • (2000) Lancet , vol.356 , pp. 291-296
    • Mocroft, A.1    Katlama, C.2    Johnson, A.M.3
  • 33
    • 53549103852 scopus 로고    scopus 로고
    • Divergent TLR7 and TLR9 signaling and type i interferon production distinguish pathogenic and nonpathogenic AIDS virus infections
    • Mandl JN, Barry AP, Vanderford TH, et al. Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. Nat Med. 2008;14: 1077-1087.
    • (2008) Nat Med , vol.14 , pp. 1077-1087
    • Mandl, J.N.1    Barry, A.P.2    Vanderford, T.H.3
  • 34
    • 58849119199 scopus 로고    scopus 로고
    • Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology
    • Baenziger S, Heikenwalder M, Johansen P, et al. Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology. Blood. 2009;113: 377-388.
    • (2009) Blood , vol.113 , pp. 377-388
    • Baenziger, S.1    Heikenwalder, M.2    Johansen, P.3
  • 35
    • 84885131818 scopus 로고    scopus 로고
    • A Role for TLR Signaling during B-cell Activation in Antiretroviral (ART) Treated HIV Individuals
    • Jun 13. [Epub ahead of print] PMCID: 23763346
    • Siewe B, Keshavarzian A, French A, Demarais P, Landay A. A role for TLR signaling during B-cell activation in antiretroviral (ART) treated HIV individuals. AIDS Res Hum Retroviruses. 2013 Jun 13. [Epub ahead of print] PMCID: 23763346
    • (2013) AIDS Res Hum Retroviruses
    • Siewe, B.1    Keshavarzian, A.2    French, A.3    Demarais, P.4    Landay, A.5
  • 36
    • 78249251478 scopus 로고    scopus 로고
    • Differential expression of Tolllike receptors in follicular lymphoma, diffuse large B-cell lymphoma and peripheral T-cell lymphoma
    • Smith TJ, Yamamoto K, Kurata M, et al. Differential expression of Tolllike receptors in follicular lymphoma, diffuse large B-cell lymphoma and peripheral T-cell lymphoma. Exp Mol Pathol. 2010;89: 284-290.
    • (2010) Exp Mol Pathol , vol.89 , pp. 284-290
    • Smith, T.J.1    Yamamoto, K.2    Kurata, M.3
  • 37
    • 70350771183 scopus 로고    scopus 로고
    • The role of toll-like receptors in chronic B-cell malignancies
    • Muzio M, Bertilaccio MT, Simonetti G, et al. The role of toll-like receptors in chronic B-cell malignancies. Leuk Lymphoma. 2009;50: 1573-1580.
    • (2009) Leuk Lymphoma , vol.50 , pp. 1573-1580
    • Muzio, M.1    Bertilaccio, M.T.2    Simonetti, G.3
  • 38
    • 58549120954 scopus 로고    scopus 로고
    • Expression and function of toll like receptors in chronic lymphocytic leukaemia cells
    • Muzio M, Scielzo C, Bertilaccio MT, et al. Expression and function of toll like receptors in chronic lymphocytic leukaemia cells. Br J Haematol. 2009;144: 507-516.
    • (2009) Br J Haematol , vol.144 , pp. 507-516
    • Muzio, M.1    Scielzo, C.2    Bertilaccio, M.T.3
  • 39
    • 0024520776 scopus 로고
    • The common acute lymphoblastic leukemia antigen (CD10) - Emancipation from a functional enigma
    • LeBien TW, McCormack RT. The common acute lymphoblastic leukemia antigen (CD10) - emancipation from a functional enigma. Blood. 1989;73: 625-635.
    • (1989) Blood , vol.73 , pp. 625-635
    • Lebien, T.W.1    McCormack, R.T.2
  • 40
    • 63849111699 scopus 로고    scopus 로고
    • Low stage follicular lymphoma: Biologic and clinical characterization according to nodal or extranodal primary origin
    • Weinberg OK, Ma L, Seo K, et al. Low stage follicular lymphoma: biologic and clinical characterization according to nodal or extranodal primary origin. Am J Surg Pathol. 2009;33: 591-598.
    • (2009) Am J Surg Pathol , vol.33 , pp. 591-598
    • Weinberg, O.K.1    Ma, L.2    Seo, K.3
  • 41
    • 79953674746 scopus 로고    scopus 로고
    • The role of toll-like receptor mediated signalling in the pathogenesis of multiple myeloma
    • Abdi J, Engels F, Garssen J, et al. The role of toll-like receptor mediated signalling in the pathogenesis of multiple myeloma. Crit Rev Oncol Hematol. 2011;80: 225-240.
    • (2011) Crit Rev Oncol Hematol , vol.80 , pp. 225-240
    • Abdi, J.1    Engels, F.2    Garssen, J.3
  • 42
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med. 2006;12: 1365-1371.
    • (2006) Nat Med , vol.12 , pp. 1365-1371
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.