Automated DBS extraction prior to hilic/RP LC-MS/MS target screening of drugs

Chromatographia

Volumn 76, Issue 19-20, 2013, Pages 1281-1293

  Versace, François ^a   Déglon, Julien ^a   Lauer, Estelle ^a   Mangin, Patrice ^a   Staub, Christian ^a  

^a UNIVERSITY CENTER OF LEGAL MEDICINE   (Switzerland)

Author keywords

Automated sample preparation; DBS; LC MS MS; Target screening

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALPHA HYDROXYMIDAZOLAM; AMITRIPTYLINE; AMPHETAMINE; AMPHETAMINE DERIVATIVE; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; BENZOYLECGONINE; CITALOPRAM; CLOZAPINE; COCAINE; CODEINE; DIAZEPAM; GLUCURONIDE; HALOPERIDOL; HOMOCOCAINE; HYDROCODONE; HYDROMORPHONE; METHADONE; METHAMPHETAMINE; MIDAZOLAM; MORPHINE; NEUROLEPTIC AGENT; OPIATE; OXYCODONE; OXYMORPHONE; PETHIDINE; TRIMIPRAMINE; UNINDEXED DRUG; ZOLPIDEM;

ARTICLE; AUTOMATION; DRIED BLOOD SPOT TESTING; DRUG SCREENING; EXTRACTION; HYDROPHILIC INTERACTION CHROMATOGRAPHY; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; RELIABILITY;

EID: 84885188490     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1007/s10337-012-2377-3     Document Type: Article

References (29)

1. Systematic toxicological analysis: laboratory guidelines (2012) The International Association of Forensic Toxicologists. http://www.tiaft.org/node/ 82. Accessed 24 Oct 2012
2. Vindenes V, Lund HME, Andresen W, Gjerde H, Ikdahl SE, Christophersen AS, Øiestad EL (2012) Detection of drugs of abuse in simultaneously collected oral fluid, urine and blood from Norwegian drug drivers. Forensic Sci Int 219:165-171
3. Viette V, Fathi M, Rudaz S, Hochstrasser D, Veuthey J-L (2011) Current role of liquid chromatography coupled to mass spectrometry in clinical toxicology screening methods. Clin Chem Lab Med 49:1091-1103
4. Parker SP, Cubitt WD (1999) The use of the dried blood spot sample in epidemiological studies. J Clin Pathol 52:633-639
5. Cartiser N, Bévalot F, Le Meur C, Gaillard Y, Malicier D, Hubert N, Guitton J (2011) Gas chromatography-tandem mass spectrometry assay for the quantification of four benzodiazepines and citalopram in eleven postmortem rabbit fluids and tissues, with application to animal and human samples. J Chromatogr B Analyt Technol Biomed Life Sci 879:2909-2918
6. Déglon J, Thomas A, Mangin P, Staub C (2012) Direct analysis of dried blood spots coupled with mass spectrometry: concepts and biomedical applications. Anal Bioanal Chem 402:2485-2498
7. Stove CP, Ingels A-SME, De Kesel PMM, Lambert WE (2012) Dried blood spots in toxicology: from the cradle to the grave? Crit Rev Toxicol 42:230-243
8. Thomas A, Geyer H, Schänzer W, Crone C, Kellmann M, Moehring T, Thevis M (2012) Sensitive determination of prohibited drugs in dried blood spots (DBS) for doping controls by means of a benchtop quadrupole/Orbitrap mass spectrometer. Anal Bioanal Chem 403:1279-1289
9. Versace F, Sporkert F, Mangin P, Staub C (2012) Rapid sample pre-treatment prior to GC-MS and GC-MS/MS urinary toxicological screening. Talanta 101:299-306
10. Peters FT (2011) Recent advances of liquid chromatography-(tandem) mass spectrometry in clinical and forensic toxicology. Clin Biochem 44:54-65
11. Jandera P, Cesla P, Hájek T, Vohralík G, Vynuchalová K, Fischer J (2008) Optimization of separation in two-dimensional high-performance liquid chromatography by adjusting phase system selectivity and using programmed elution techniques. J Chromatogr A 1189:207-220
12. Thomas A, Déglon J, Steimer T, Mangin P, Daali Y, Staub C (2010) On-line desorption of dried blood spots coupled to hydrophilic interaction/reversed-phase LC/MS/MS system for the simultaneous analysis of drugs and their polar metabolites. J Sep Sci 33:873-879
13. Shushan BI, Marquet P, Dupuy JL, Anacleto J, Lachâtre G, Duchoslav E, Chan M (1999) Development of a toxicant screening procedure using liquid chromatography-electrospray-mass-spectrometry (LC-ESMS). Ther Drug Monit 21:467
14. Marquet P, Venisse N, Lacassie E, Lachâtre G (2000) In-source CID mass spectral libraries for the "general unknown" screening of drugs and toxicants. Analusis 28:925-934
15. Marquet P (2002) Is LC-MS suitable for a comprehensive screening of drugs and poisons in clinical toxicology? Ther Drug Monit 24:125
16. Sturm S, Hammann F, Drewe J, Maurer HH, Scholer A (2010) An automated screening method for drugs and toxic compounds in human serum and urine using liquid chromatography-tandem mass spectrometry. J Chromatogr B 878:2726-2732
17. Sauvage F-L, Picard N, Saint-Marcoux F, Gaulier J-M, Lachâtre G, Marquet P (2009) General unknown screening procedure for the characterization of human drug metabolites in forensic toxicology: applications and constraints. J Sep Sci 32:3074-3083
18. Liu H-C, Liu RH, Lin D-L, Ho H-O (2010) Rapid screening and confirmation of drugs and toxic compounds in biological specimens using liquid chromatography/ion trap tandem mass spectrometry and automated library search. Rapid Commun Mass Spectrom 24:75-84
19. Mueller C, Weinmann W, Dresen S (2005) Development of a multi-target screening analysis for 301 drugs using a QTrap liquid chromatography/tandem mass spectrometry system and automated library searching. Rapid Commun Mass Spectrom 19:1332-1338
20. Viette V, Guillarme D, Mylonas R, Mauron Y, Fathi M, Rudaz S, Hochstrasser D, Veuthey J-L (2011) A multi-target screening analysis in human plasma using fast liquid chromatography-hybrid tandem mass spectrometry (Part I). Clin Biochem 44:32-44
21. Viette V, Guillarme D, Mylonas R, Mauron Y, Fathi M, Rudaz S, Hochstrasser D, Veuthey J-L (2011) A multi-target screening analysis in human plasma using fast liquid chromatography-hybrid tandem mass spectrometry (Part II). Clin Biochem 44:45-53
22. Thomas A, Hopfgartner G, Giroud C, Staub C (2009) Quantitative and qualitative profiling of endocannabinoids in human plasma using a triple quadrupole linear ion trap mass spectrometer with liquid chromatography. Rapid Commun Mass Spectrom 23:629-638
23. Mueller DM, Rentsch KM (2012) Online extraction toxicological MS(n) screening system for serum and heparinized plasma and comparison of screening results between plasma and urine in the context of clinical data. J Chromatogr B Analyt Technol Biomed Life Sci 883-884:189-197
24. McCauley-Myers DL, Eichhold TH, Bailey RE (2000) Rapid bioanalytical determination of dextromethorphan in canine plasma by dilute-and-shoot preparation combined with one minute per sample LC-MS/MS analysis to optimize formulations for drug delivery. J Pharmaceut Biomed 23:825-835
25. Li F, Ploch S (2012) Will "green" aspects of dried blood spot sampling accelerate its implementation and acceptance in the pharmaceutical industry? Bioanalysis 4:1259-1261
26. Déglon J, Versace F, Lauer E, Widmer C, Mangin P, Thomas A, Staub C (2012) Rapid LC-MS/MS quantification of the major benzodiazepines and their metabolites on dried blood spots using a simple and cost-effective sample pretreatment. Bioanalysis 4:1337-1350
27. Matuszewski BK, Constanzer ML, Chavez-Eng CM (2003) Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal Chem 75:3019-3030
28. Iwersen-Bergmann S, Andresen H, Schmoldt A (2012) Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics. Crit Care 16:R136
29. Ordonnance de l'OFROU concernant l'ordonnace sur le contrôle de la circulation routière, art. 34 (2012) The Federal Authorities of the Swiss Confederation. http://www.admin.ch/ch/f/rs/741-013-1/a34.html. Accessed 24 Oct 2012