An automated screening method for drugs and toxic compounds in human serum and urine using liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 28, 2010, Pages 2726-2732

  Sturm, Stefan ^a   Hammann, Felix ^a   Drewe, Juergen ^a   Maurer, Hans H ^b   Scholer, André ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Data dependent acquisition; General unknown screening; Toxic compounds

Indexed keywords

AUTOMATED SCREENING; DATA-DEPENDENT ACQUISITION; FRAGMENT IONS; GENERAL UNKNOWN SCREENING; HUMAN SERUM; LC-MS-MS; LIBRARY SEARCH; LIMITS OF DETECTION; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MOLECULAR IONS; RELATIVE RETENTION TIME; SCREENING METHODS; SPECTROMETRIC METHODS; TOXIC COMPOUNDS; URINE SAMPLE;

BODY FLUIDS; LIQUIDS; MASS SPECTROMETRY; TOXICITY;

LIQUID CHROMATOGRAPHY;

ACETYLSALICYLIC ACID; AMOBARBITAL; BISACODYL; BUPIVACAINE; BUTALBITAL; CARBROMAL; CITALOPRAM; COUMAFOS; EPHEDRINE; GLIBENCLAMIDE; GLIBORNURIDE; GLICLAZIDE; IBUPROFEN; METHYLPHENIDATE; MORPHINE; NAPROXEN; OLANZAPINE; PENTOBARBITAL; PHENOLPHTHALEIN; PHENPROCOUMON; PROPRANOLOL; SALICYLIC ACID; SECOBARBITAL; SPIRONOLACTONE; THIOPENTAL; TORASEMIDE; TOXIC SUBSTANCE;

ARTICLE; LIQUID CHROMATOGRAPHY; METHODOLOGY; PRIORITY JOURNAL; SCREENING; SERUM; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; URINALYSIS;

AUTOMATION, LABORATORY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DATABASES, FACTUAL; HUMANS; PHARMACEUTICAL PREPARATIONS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 77957303073     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.08.013     Document Type: Article

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