A multi-target screening analysis in human plasma using fast liquid chromatography-hybrid tandem mass spectrometry (Part I)

Clinical Biochemistry

Volumn 44, Issue 1, 2011, Pages 32-44

  Viette, V ^a,b,d   Guillarme, D ^d   Mylonas, R ^c   Mauron, Y ^c   Fathi, M ^a,d   Rudaz, S ^d   Hochstrasser, D ^a,d   Veuthey, J L ^d  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b ADMed Laboratoires   (Switzerland)

^c SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^d UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Drugs; Fast LC; LC MS MS; Library; Matrix effect; Remedi ; Screening; Solid phase extraction

Indexed keywords

ARTICLE; CLINICAL LABORATORY; DRUG ABUSE; DRUG SCREENING; FAST PROTEIN LIQUID CHROMATOGRAPHY; HUMAN; METABOLITE; PRIORITY JOURNAL; SERUM; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, LIQUID; HUMANS; PHARMACEUTICAL PREPARATIONS; SOLID PHASE EXTRACTION; SUBSTANCE-RELATED DISORDERS; TANDEM MASS SPECTROMETRY;

EID: 78650859174     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2010.07.021     Document Type: Article

References (41)

1. Mueller C.A., Weinmann W., Dressen S., Schreiber A., Gergov M. Development of a multi-target screening analysis for 301 drugs using a QTrap liquid chromatography/tandem mass spectrometry system and automated library searching. Rapid Commun Mass Spectrom 2005, 19:1332-1338.
2. Gergov M., Robson J.N., Ojanperä I., Heinonen O.P., Vuori E. Simultaneous screening and quantitation of 18 antihistamine drugs in blood by liquid chromatography ionspray tandem mass spectrometry. Forensic Sci Int 2001, 121:108-115.
3. Herrin G.L., McCurdy H.H., Wall W.H. Investigation of an LC-MS-MS (QTrap) method for the rapid screening and identification of drugs in postmortem toxicology whole blood samples. J Anal Toxicol 2005, 29:599-606.
4. Marquet P. Systematic toxicological analysis with LC-MS. Application of LC-MS in toxicology 2006, 111-127. Pharmaceutical Press, London, UK. A. Polettini (Ed.).
5. Weinmann W., Stoertzel M., Vogt S., Svoboda M., Schreiber A. Tuning compounds for electrospray ionization/in-source collision-induced dissociation and mass spectra library searching. J Mass Spectrom 2001, 36:1013-1023.
6. Weinmann W., Stoertzel M., Vogt S., Wendt J. Tune compounds for electrospray ionization/in-source collision-induced dissociation with mass spectral library searching. J Chromatogr A 2001, 926:199-209.
7. Marquet P., Venisse N., Lacassie E., Lachâtre G. In-source CID mass spectral libraries for the general unknown screening of drugs and toxicants. Analusis 2000, 28:925-934.
8. Schreiber A., Efer J., Engelwald W. Application of spectral libraries for high-performance liquid chromatography-atmospheric pressure ionisation mass spectrometry to the analysis of pesticide and explosive residues in environmental samples. J Chromatogr A 2000, 869:411-425.
9. Gergov M., Ojanperä I., Vuori E. Simultaneous screening for 238 drugs in blood by liquid chromatography-ionspray tandem mass spectrometry with multiple-reaction monitoring. J Chromatogr B 2003, 795:41-53.
10. Hager J.W. A new linear ion trap mass spectrometer. Rapid Commun Mass Spectrom 2002, 16:512-526.
11. Maurer H.H. Mass spectrometric approaches in impaired driving toxicology. Anal Bioanal Chem 2009, 393:97-107.
12. Sauvage F.L., Saint-Marcoux F., Duretz B., Deporte D., Lachâtre G., Marquet P. Screening of drugs and toxic compounds with liquid chromatography-linear ion trap tandem mass spectrometry. Clin Chem 2006, 52:1735-1742.
13. Kircherr H., Kühn-Velten W.N. Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach. J Chromatogr B 2006, 843:100-113.
14. Pozo O.J., Van Eeno P., Deventer K., Delbeke F.T. Development and validation of a qualitative screening method fort he detection of exogenous anabolic steroids in urine by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 2007, 389:1209-1224.
15. Nguyen D.T.T., Guillarme D., Rudaz S., Veuthey J.L. Fast analysis in liquid chromatography using small particle partcle size and high pressure. J Sep Sci 2006, 29:1836-1848.
16. Guillarme D., Grata E., Glauser G., Wolfender J.L., Veuthey J.L., Rudaz S. Some solutions to obtain very efficient separations in isocratic and gradient modes using small particle size and ultra-high pressure. J Chromatogr A 2009, 1216:3232-3243.
17. Guillarme D., Schappler J., Rudaz S., Veuthey J.L. Coupling ultra-high-pressure liquid chromatography with mass spectrometry. Trends Anal Chem 2010, 29:15-27.
18. Maurer H.H. Hypenated mass spectrometric techniques - indispensable tools in clinical and forensic toxicology and in doping control. J Mass Spectrom 2006, 41:1399-1413.
19. Peters F.T. Method Validation using LC-MS. Application of LC-MS in toxicology 2006, 71-90. Pharmaceutical Press, London, UK. A. Polettini (Ed.).
20. Souverain S., Rudaz S., Veuthey J.L. Matrix effect in LC-ESI-MS and LC-APCI-MS with off-line and on-line extraction procedures. J Chromatogr A 2004, 1058:61-66.
21. Mei H., Hsieh Y., Nardo C., et al. Investigation of matrix effects in bioanalytical high-performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery. Rapid Commun Mass Spectrom 2003, 17:97-103.
22. Matuszewski B.K., Constanzer M.L., Chavez-Eng C.M. Matrix effect in quantitative LC/MS/MS analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per millilitre concentrations. Anal Chem 1998, 70:882-889.
23. Taylor P.J. Matrix effects: the Achilles heel of quantitative high-performance liquid chromatography-electrospray-tandem mass spectrometry. Clin Biochem 2005, 38:328-334.
24. Matuszewski B.K., Constanzer M.L., Chavez-Eng C.M. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal Chem 2003, 75:3019-3030.
25. Marchi I., Rudaz S., Veuthey J.L. Sample preparation development and matrix effects evaluation for multianalyte determination in urine. J Pharm Biomed Anal 2009, 49:459-467.
26. Bonfiglio R., King R.C. The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds. Rapid Commun Mass Spectrom 1999, 13:1175-1185.
27. Peters F.T., Drummer O.H., Musshoff F. Validation of new methods. Forensic Sci Int 2007, 165:216-224.
28. Rivier L. Criteria for the identification of compounds by liquid chromatography-mass spectrometry and liquid chromatography-multiple mass spectrometry in forensic toxicology and doping analysis. Anal Chim Acta 2003, 492:69-82.
29. Rivier L. Identification and confirmation criteria for LC-MS. Application of LC-MS in toxicology 2006, 97-108. Pharmaceutical Press, London, UK. A. Polettini (Ed.).
30. Ojanperä S., Pelander A., Pelzing M., Krebs I., Vuori E., Ojanperä I. Isotopic pattern and accurate mass determination in urine drug screening by liquid chromatography/time-of-flight mass spectrometry. Rapid Commun Mass Spectrom 2006, 20:1161-1167.
31. Mylonas R., Mauron Y., Masselot A., et al. X-Rank: a robust algortithm for small molecule identification using tandem mass spectrometry. Anal Chem 2009, 81:7604-7610.
32. Guillarme D., Nguyen D.T.T., Rudaz S., Veuthey J.L. Recent developments in liquid chromatography - impact on qualitative and quantitative performance. J Chromatogr A 2007, 1149:20-29.
33. Wren S.A. Peak capacity in gradient ultra performance liquid chromatography (UPLC). J Pharm Biomed Anal 2005, 38:337-343.
34. Petersson P., Frank A., Heaton J., Euerby M.R. Maximizing peak capacity and separation speed in liquid chromatography. J Sep Sci 2008, 31:2346-2357.
35. Remedi™ HS, DPS and UBZ Drug Library Listing Releases 4.3X.35/5.3X.33/5.1X.33.
36. Schulz M., Schmoldt A. Therapeutic and toxic blood concentrations of more than 800 drugs and other xenobiotics. Pharmazie 2003, 58:447-474.
37. King R., Bonfiglio R. Mechanistic investigation of ionization suppression in electrospray ionization. J Am Soc Mass Spectrom 2000, 11:942-950.
38. Bugey A., Rudaz S., Staub C. A fast LC-APCI/MS method for analyzing benzodiazepines in whole blood using monolithic support. J Chromatogr B 2006, 832:249-255.
39. Gergov M., Nokua P., Vuori E., Ojanperä I. Simultaneous screening and quantification of 25 opioid drugs in post-mortem blood and urine by liquid chromatography-tandem mass spectrometry. Forensic Sci Int 2009, 186:36-43.
40. Feng J., Wang L., Dai I., Harmon T., Bernert J. Simultaneous determination of multiple drugs of abuse and relevant metabolites in urine by LC-MS-MS. J Anal Toxicol 2007, 31:359-368.
41. Allen K.R. Interference by venlafaxine ingestion in the detection of tramadol by liquid chromatography linked to tandem mass spectrometry for the screening of illicit drugs in human urine. Clin Toxicol 2006, 44:147-153.