Online extraction toxicological MS(n) screening system for serum and heparinized plasma and comparison of screening results between plasma and urine in the context of clinical data

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 883-884, Issue , 2012, Pages 189-197

  Mueller, Daniel M ^a   Rentsch, Katharina M ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Clinical toxicology; LC MS; Online extraction; Toxicological screening; Turbulent flow chromatography

Indexed keywords

ALKALINE CONDITIONS; CHROMATOGRAPHIC SEPARATIONS; CLINICAL DATA; CLINICAL TOXICOLOGY; DETECTION WINDOWS; ELUENTS; LC-MS; LC-MS N; LINEAR ION TRAP; MATRIX EFFECTS; ONLINE EXTRACTION; PLASMA SAMPLES; QUANTITATIVE MATRICES; SCREENING SYSTEM; SPECTRAL LIBRARIES; THERAPEUTIC RANGE;

COLUMN CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MATRIX ALGEBRA; PLASMAS; TURBULENT FLOW;

BODY FLUIDS;

ALKALINITY; ARTICLE; CLINICAL ARTICLE; CLINICAL STUDY; CONTROLLED STUDY; EXTRACTION; HEPARINIZED PLASMA; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ONLINE EXTRACTION; PLASMA; PRIORITY JOURNAL; SCREENING; TOXICITY TESTING; TURBULENT FLOW; URINALYSIS; VALIDATION STUDY;

CHROMATOGRAPHY, LIQUID; HUMANS; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TOXICOLOGY;

EID: 84856420996     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.08.022     Document Type: Article

References (18)

1. Linder M.W., Bosse G.M., Henderson M.T., Midkiff G., Valdes R. Clin. Chim. Acta 2000, 295:179.
2. Sturm S., Hammann F., Drewe J., Maurer H.H., Scholer A. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2010, 878:2726.
3. Liu H.C., Liu R.H., Lin D.L., Ho H.O. Rapid Commun. Mass Spectrom. 2010, 24:75.
4. Marquet P., Saint-Marcoux F., Gamble T.N., Leblanc J.C. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2003, 789:9.
5. Saint-Marcoux F., Lachatre G., Marquet P. J. Am. Soc. Mass Spectrom. 2003, 14:14.
6. Sauvage F.L., Saint-Marcoux F., Duretz B., Deporte D., Lachatre G., Marquet P. Clin. Chem. 2006, 52:1735.
7. Dresen S., Ferreiros N., Gnann H., Zimmermann R., Weinmann W. Anal. Bioanal. Chem. 2010, 396:2425.
8. Viette V., Guillarme D., Mylonas R., Mauron Y., Fathi M., Rudaz S., Hochstrasser D., Veuthey J.L. Clin. Biochem. 2011, 44:45.
9. Viette V., Guillarme D., Mylonas R., Mauron Y., Fathi M., Rudaz S., Hochstrasser D., Veuthey J.L. Clin. Biochem. 2011, 44:32.
10. Mueller D.M., Duretz B., Espourteille F.A., Rentsch K.M. Anal. Bioanal. Chem. 2010, 400:89.
11. Bonfiglio R., King R.C., Olah T.V., Merkle K. Rapid Commun. Mass Spectrom. 1999, 13:1175.
12. Matuszewski B.K., Constanzer M.L., Chavez-Eng C.M. Anal. Chem. 2003, 75:3019.
13. Schulz M., Schmoldt A. Pharmazie 2003, 58:447.
14. D. Uges, TIAFT reference blood level list of therapeutic and toxic substances, 2004.
15. Baselt R. Disposition of Toxic Drugs and Chemicals in Man 2008, Biomedical Publications, Foster City. 8th ed.
16. Baumann P., Hiemke C., Ulrich S., Eckermann G., Gaertner I., Gerlach M., Kuss H.J., Laux G., Muller-Oerlinghausen B., Rao M.L., Riederer P., Zernig G. Pharmacopsychiatry 2004, 37:243.
17. Ismaiel O.A., Halquist M.S., Elmamly M.Y., Shalaby A., Thomas Karnes H. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2008, 875:333.
18. Moffat A., Osselton M., Widdop B. Clarke's Analysis of Drugs and Poisons 2004, Pharmaceutical Press, London. 3rd ed.