Rapid LC-MS/MS quantification of the major benzodiazepines and their metabolites on dried blood spots using a simple and cost-effective sample pretreatment

Bioanalysis

Volumn 4, Issue 11, 2012, Pages 1337-1350

  Déglon, Julien ^a   Versace, François ^a   Lauer, Estelle ^a   Widmer, Christèle ^a   Mangin, Patrice ^a   Thomas, Aurélien ^a   Staub, Christian ^a  

^a UNIVERSITY CENTER OF LEGAL MEDICINE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

7 AMINOCLONAZEPAM; 7 AMINOCLONAZEPAM D4; 7 AMINOFLUNITRAZEPAM; ALPRAZOLAM; BENZODIAZEPINE DERIVATIVE; CLOBAZAM; CLONAZEPAM; DEALKYLFLURAZEPAM; DIAZEPAM; FLUNITRAZEPAM; FLURAZEPAM; LORAZEPAM; LORMETAZEPAM; MIDAZOLAM; NITRAZEPAM; NORDAZEPAM; NORDIAZEPAM D5; NORFLUNITRAZEPAM; OXAZEPAM; PRAZEPAM; TEMAZEPAM; TRIAZOLAM; UNCLASSIFIED DRUG; ZALEPLON; ZALEPLON D5; ZOLPIDEM; ZOLPIDEM D6; ZOPICLONE;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DRIED BLOOD SPOT TESTING; ENVIRONMENTAL IMPACT; EVAPORATION; FLOW RATE; HIGH THROUGHPUT SCREENING; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; PARTICLE SIZE; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY;

BENZODIAZEPINES; BLOOD SPECIMEN COLLECTION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRIED BLOOD SPOT TESTING; HUMANS; METHANOL; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 84862878040     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.12.42     Document Type: Article

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