Diphenytoin, riluzole and lidocaine: Three sodium channel blockers, with different mechanisms of action, decrease hippocampal epileptiform activity

Neuropharmacology

Volumn 73, Issue , 2013, Pages 48-55

  Diao, Lihong ^a   Hellier, Jennifer L ^a   Uskert Newsom, Jessica ^a   Williams, Philip A ^a   Staley, Kevin J ^b   Yee, Audrey S ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

CA3; Diphenytoin; Epilepsy; Hyperexcitability; Lidocaine; Riluzole

Indexed keywords

LIDOCAINE; PHENYTOIN; RILUZOLE; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN REGION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; EVOKED RESPONSE; HIPPOCAMPAL CA3 REGION; IN VITRO STUDY; NEUROPROTECTION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PHENOTYPE; PRIORITY JOURNAL;

CA3; DIPHENYTOIN; EPILEPSY; HYPEREXCITABILITY; LIDOCAINE; RILUZOLE;

ACTION POTENTIALS; ANIMALS; CA3 REGION, HIPPOCAMPAL; ELECTRIC STIMULATION; EVOKED POTENTIALS; LIDOCAINE; MALE; PHENYTOIN; RATS; RILUZOLE; VOLTAGE-GATED SODIUM CHANNEL BLOCKERS;

EID: 84885152307     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.04.057     Document Type: Article

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