N-ethyl lidocaine (QX-314) protects striatal neurons against ischemia: An in vitro electrophysiological study

Synapse

Volumn 64, Issue 2, 2010, Pages 161-168

  Armogida, Marta ^a   Giustizieri, Michela ^a   Zona, Cristina ^a,b   Piccirilli, Silvia ^c   Nisticò, Robert ^a,d   Mercuri, Nicola B ^a,b  

^a EUROPEAN BRAIN RESEARCH INSTITUTE   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c C MONDINO NATIONAL NEUROLOGICAL INSTITUTE   (Italy)

^d UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Field potentials; Ischemia; Ischemic depolarization; Medium spiny neurons; Neuroprotection; Patch clamp; Sodium channel blockers; Synaptic transmission

Indexed keywords

GLUCOSE; LIDOCAINE; LIDOCAINE ETHOBROMIDE; OXYGEN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN ISCHEMIA; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; DEPOLARIZATION; DRUG EFFECT; ELECTRIC POTENTIAL; EVOKED RESPONSE; EXCITATORY POSTSYNAPTIC POTENTIAL; IN VITRO STUDY; MALE; NERVE CELL; NERVE CONDUCTION; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT; SPIKE WAVE;

ANIMALS; BRAIN ISCHEMIA; CELL HYPOXIA; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; LIDOCAINE; MALE; MEMBRANE POTENTIALS; MICROELECTRODES; NEOSTRIATUM; NEURAL PATHWAYS; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; SODIUM; SODIUM CHANNEL BLOCKERS;

EID: 72449179416     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20735     Document Type: Article

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