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Volumn 31, Issue 1, 1998, Pages 73-84

Recurrent spontaneous motor seizures after repeated low-dose systemic treatment with kainate: Assessment of a rat model of temporal lobe epilepsy

Author keywords

Animal model; Convulsions; Epileptogenesis; Hippocampus; Kainic acid; Temporal lobe

Indexed keywords

KAINIC ACID; SODIUM CHLORIDE;

EID: 0031747177     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(98)00017-5     Document Type: Article
Times cited : (324)

References (46)
  • 2
    • 0021921141 scopus 로고
    • Limbic seizure and brain damage produced by kainic acid: Mechanisms and relevance to human temporal lobe epilepsy
    • Ben-Ari Y. Limbic seizure and brain damage produced by kainic acid: mechanisms and relevance to human temporal lobe epilepsy. Neuroscience. 14:1985;375-403.
    • (1985) Neuroscience , vol.14 , pp. 375-403
    • Ben-Ari, Y.1
  • 3
    • 0027432432 scopus 로고
    • The ontogeny of seizures in a rat model of limbic epilepsy: Evidence for a kindling process in the development of chronic spontaneous seizures
    • Bertram E.H., Cornett J.F. The ontogeny of seizures in a rat model of limbic epilepsy: evidence for a kindling process in the development of chronic spontaneous seizures. Brain Res. 625:1993;295-300.
    • (1993) Brain Res. , vol.625 , pp. 295-300
    • Bertram, E.H.1    Cornett, J.F.2
  • 4
    • 0028149673 scopus 로고
    • The evolution of a rat model of chronic spontaneous limbic seizures
    • Bertram E.H., Cornett J.F. The evolution of a rat model of chronic spontaneous limbic seizures. Brain Res. 661:1994;157-162.
    • (1994) Brain Res. , vol.661 , pp. 157-162
    • Bertram, E.H.1    Cornett, J.F.2
  • 5
    • 1842298190 scopus 로고    scopus 로고
    • Network properties of the dentate gyrus in epileptic rats with hilar neuron loss and granule cell axon reorganization
    • Buckmaster P.S., Dudek F.E. Network properties of the dentate gyrus in epileptic rats with hilar neuron loss and granule cell axon reorganization. J. Neurophysiol. 77:1997;2685-2696.
    • (1997) J. Neurophysiol. , vol.77 , pp. 2685-2696
    • Buckmaster, P.S.1    Dudek, F.E.2
  • 6
    • 0030773376 scopus 로고    scopus 로고
    • Neuron loss, granule cell reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats
    • Buckmaster P.S., Dudek F.E. Neuron loss, granule cell reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats. J. Comp. Neurol. 385:1997;385-404.
    • (1997) J. Comp. Neurol. , vol.385 , pp. 385-404
    • Buckmaster, P.S.1    Dudek, F.E.2
  • 7
    • 0029014398 scopus 로고
    • The pilocarpine model of epilepsy
    • Cavalheiro E.A. The pilocarpine model of epilepsy. Ital. J. Neurol. Sci. 16:1995;33-37.
    • (1995) Ital. J. Neurol. Sci. , vol.16 , pp. 33-37
    • Cavalheiro, E.A.1
  • 8
    • 0029790315 scopus 로고    scopus 로고
    • The pilocarpine model of epilepsy in mice
    • Cavalheiro E.A., Santos N.F., Price M.I. The pilocarpine model of epilepsy in mice. Epilepsia. 37:1996;1015-1019.
    • (1996) Epilepsia , vol.37 , pp. 1015-1019
    • Cavalheiro, E.A.1    Santos, N.F.2    Price, M.I.3
  • 9
    • 0019952583 scopus 로고
    • Long-term effects of intrahippocampal kainic acid injection in rats: A method for inducing spontaneous recurrent seizures
    • Cavalheiro E.A., Richie D.A., Le Gal La Salle G. Long-term effects of intrahippocampal kainic acid injection in rats: a method for inducing spontaneous recurrent seizures. Electroencephalogr. Clin. Neurophysiol. 53:1982;581-589.
    • (1982) Electroencephalogr. Clin. Neurophysiol. , vol.53 , pp. 581-589
    • Cavalheiro, E.A.1    Richie, D.A.2    Le Gal La Salle, G.3
  • 10
    • 0026340904 scopus 로고
    • Long-term effects of pilocarpine in rats, structural damage of the brain triggers kindling and spontaneous recurrent seizures
    • Cavalheiro E.A., Leite J.P., Bortolotto Z.A., Turski W.A., Ikonomidou C., Turski L. Long-term effects of pilocarpine in rats, structural damage of the brain triggers kindling and spontaneous recurrent seizures. Epilepsia. 32:1991;778-782.
    • (1991) Epilepsia , vol.32 , pp. 778-782
    • Cavalheiro, E.A.1    Leite, J.P.2    Bortolotto, Z.A.3    Turski, W.A.4    Ikonomidou, C.5    Turski, L.6
  • 11
    • 0028286992 scopus 로고
    • Neuronal loss induced in limbic pathways by kindling: Evidence for induction of hippocampal sclerosis by repeated brief seizures
    • Cavazos J.E., Das I., Sutula T.P. Neuronal loss induced in limbic pathways by kindling: evidence for induction of hippocampal sclerosis by repeated brief seizures. J. Neurosci. 14:1994;3106-3121.
    • (1994) J. Neurosci. , vol.14 , pp. 3106-3121
    • Cavazos, J.E.1    Das, I.2    Sutula, T.P.3
  • 12
    • 25544449063 scopus 로고
    • Appendix B: Protocol for revised classification of epilepsies and epileptic syndromes
    • Chapman and Hall Medical, London
    • Commission on Classification and Terminology of the International League Against Epilepsy, 1995. Appendix B: Protocol for revised classification of epilepsies and epileptic syndromes. In: Hopkins, A., Shorvon, S., Cascino, G., (Eds.), Epilepsy, 2nd ed. Chapman and Hall Medical, London, pp. 637-651.
    • (1995) Epilepsy, 2nd Ed. , pp. 637-651
    • Hopkins, A.1    Shorvon, S.2    Cascino, G.3
  • 13
    • 0024208367 scopus 로고
    • Chronic seizures and collateral sprouting of dentate mossy fibers after kainic acid treatment in rats
    • Cronin J., Dudek F.E. Chronic seizures and collateral sprouting of dentate mossy fibers after kainic acid treatment in rats. Brain Res. 474:1988;181-184.
    • (1988) Brain Res. , vol.474 , pp. 181-184
    • Cronin, J.1    Dudek, F.E.2
  • 14
    • 0026558337 scopus 로고
    • Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fibers
    • Cronin J., Obenaus A., Houser C.R., Dudek F.E. Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fibers. Brain Res. 573:1992;305-310.
    • (1992) Brain Res. , vol.573 , pp. 305-310
    • Cronin, J.1    Obenaus, A.2    Houser, C.R.3    Dudek, F.E.4
  • 15
    • 0024412565 scopus 로고
    • Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy
    • De Lanerolle N.C., Kim J.H., Robbins R.J., Spencer D.D. Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy. Brain Res. 495:1989;387-395.
    • (1989) Brain Res. , vol.495 , pp. 387-395
    • De Lanerolle, N.C.1    Kim, J.H.2    Robbins, R.J.3    Spencer, D.D.4
  • 17
    • 0003087379 scopus 로고
    • Who should be considered a surgical candidate?
    • Engel, J.J. (Ed.), Raven Press, New York
    • Engel, J.J., Shewmon, D.A., 1993. Who should be considered a surgical candidate? In: Engel, J.J. (Ed.), Surgical Treatment of the Epilepsies. Raven Press, New York, pp. 23-34.
    • (1993) Surgical Treatment of the Epilepsies , pp. 23-34
    • Engel, J.J.1    Shewmon, D.A.2
  • 18
    • 0014340453 scopus 로고
    • Surgical treatment of drug-resistant epilepsy due to mesial temporal sclerosis
    • Falconer M.A., Taylor D.C. Surgical treatment of drug-resistant epilepsy due to mesial temporal sclerosis. Arch. Neurol. 19:1968;353-361.
    • (1968) Arch. Neurol. , vol.19 , pp. 353-361
    • Falconer, M.A.1    Taylor, D.C.2
  • 19
    • 0002363126 scopus 로고
    • Psychiatric disorders and epilepsy
    • Hopkins, A., Shorvon, S., Cascino, G., (Eds.), Chapman and Hall Medical, London
    • Fenwick, P., 1995. Psychiatric disorders and epilepsy. In: Hopkins, A., Shorvon, S., Cascino, G., (Eds.), Epilepsy. Chapman and Hall Medical, London, pp. 453-502.
    • (1995) Epilepsy , pp. 453-502
    • Fenwick, P.1
  • 23
    • 0002303112 scopus 로고
    • Definitions and epidemiology of epilepsy
    • Hopkins, A., Shorvon, S., Cascino, G. (Eds.), Chapman and Hall Medical, London
    • Hopkins, A., Shorvon, S., 1995. Definitions and epidemiology of epilepsy. In: Hopkins, A., Shorvon, S., Cascino, G. (Eds.), Epilepsy. Chapman and Hall Medical, London, pp. 1-24.
    • (1995) Epilepsy , pp. 1-24
    • Hopkins, A.1    Shorvon, S.2
  • 24
    • 0025326575 scopus 로고
    • Recurrent spontaneous hippocampal seizures in the rat as a chronic sequela to limbic status epilepticus
    • Lothman F.W., Bertram E.H., Kapur J., Stringer J.L. Recurrent spontaneous hippocampal seizures in the rat as a chronic sequela to limbic status epilepticus. Epilepsy Res. 6:1990;110-118.
    • (1990) Epilepsy Res. , vol.6 , pp. 110-118
    • Lothman, F.W.1    Bertram, E.H.2    Kapur, J.3    Stringer, J.L.4
  • 25
    • 0002973096 scopus 로고
    • Onset and patterns of hippocampal sprouting in the rat kainate seizure model: Evidence for progressive cell loss and neo-innervation in regio inferior and superior
    • Mathern G.W., Kupfer W.R., Pretorius J.K., Babb T.L., Levesque M.F. Onset and patterns of hippocampal sprouting in the rat kainate seizure model: evidence for progressive cell loss and neo-innervation in regio inferior and superior. Dendron. 1:1992;69-84.
    • (1992) Dendron , vol.1 , pp. 69-84
    • Mathern, G.W.1    Kupfer, W.R.2    Pretorius, J.K.3    Babb, T.L.4    Levesque, M.F.5
  • 26
    • 0027442075 scopus 로고
    • Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model
    • Mathern G.W., Cifuentes F., Leite J.P., Pretorius J.K., Babb T.L. Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model. Electroencephalogr. Clin. Neurophysiol. 87:1993;326-339.
    • (1993) Electroencephalogr. Clin. Neurophysiol. , vol.87 , pp. 326-339
    • Mathern, G.W.1    Cifuentes, F.2    Leite, J.P.3    Pretorius, J.K.4    Babb, T.L.5
  • 27
    • 0028939689 scopus 로고
    • The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy
    • Mathern G.W., Babb T.L., Vickrey B.G., Melendez M., Pretorius J.K. The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy. Brain. 118:1995;105-118.
    • (1995) Brain , vol.118 , pp. 105-118
    • Mathern, G.W.1    Babb, T.L.2    Vickrey, B.G.3    Melendez, M.4    Pretorius, J.K.5
  • 29
    • 0022600145 scopus 로고
    • Kindling model of epilepsy
    • Delgado-Escueta, A., Ward, A., Woodbury, D., Porter, R., (Eds.), Basic Mechanisms in Epilepsy. Raven Press, New York
    • McNamara, J., 1986. Kindling model of epilepsy. In: Delgado-Escueta, A., Ward, A., Woodbury, D., Porter, R., (Eds.), Basic Mechanisms in Epilepsy. Raven Press, New York, Adv. Neurol. 44, 303-318.
    • (1986) Adv. Neurol. , vol.44 , pp. 303-318
    • McNamara, J.1
  • 30
    • 0029858175 scopus 로고    scopus 로고
    • Spontaneous and stimulation-induced synchronized burst afterdischarges in the isolated CA1 of kainate-treated rats
    • Meier C.L., Dudek F.E. Spontaneous and stimulation-induced synchronized burst afterdischarges in the isolated CA1 of kainate-treated rats. J. Neurophysiol. 76:1996;2231-2239.
    • (1996) J. Neurophysiol. , vol.76 , pp. 2231-2239
    • Meier, C.L.1    Dudek, F.E.2
  • 31
    • 0027080794 scopus 로고
    • Persistent hyperexcitability in isolated hippocampal CA1 of kainate-lesioned rats
    • Meier C.L., Obenaus A., Dudek F.E. Persistent hyperexcitability in isolated hippocampal CA1 of kainate-lesioned rats. J. Neurophysiol. 68:1992;2120-2127.
    • (1992) J. Neurophysiol. , vol.68 , pp. 2120-2127
    • Meier, C.L.1    Obenaus, A.2    Dudek, F.E.3
  • 32
    • 0027143716 scopus 로고
    • Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: Cell loss and mossy fiber sprouting
    • Mello L.E.A.M., Cavalheiro E.A., Tan A.M., Kupfer W.R., Pretorius J.K., Babb T., Finch D.M. Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting. Epilepsia. 34:1993;985-995.
    • (1993) Epilepsia , vol.34 , pp. 985-995
    • Mello, L.E.A.M.1    Cavalheiro, E.A.2    Tan, A.M.3    Kupfer, W.R.4    Pretorius, J.K.5    Babb, T.6    Finch, D.M.7
  • 33
    • 0018907951 scopus 로고
    • Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid
    • Nadler J.V., Perry B.W., Cotman C.W. Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid. Brain Res. 182:1980;1-9.
    • (1980) Brain Res. , vol.182 , pp. 1-9
    • Nadler, J.V.1    Perry, B.W.2    Cotman, C.W.3
  • 34
    • 0002265656 scopus 로고    scopus 로고
    • Surgical therapy of epilepsy
    • Brandt, T., Caplan, L.R., Dichgans, J., Diener, H.C., Kennard, C. (Eds.), Academic Press
    • Noachtar, S., Lüders, H., Bromfield, E.B., 1996. Surgical therapy of epilepsy. In: Brandt, T., Caplan, L.R., Dichgans, J., Diener, H.C., Kennard, C. (Eds.), Neurological Disorders: Course and Treatment. Academic Press, pp. 183-191.
    • (1996) Neurological Disorders: Course and Treatment , pp. 183-191
    • Noachtar, S.1    Lüders, H.2    Bromfield, E.B.3
  • 35
    • 0031952614 scopus 로고    scopus 로고
    • Physiological unmasking of new glutamatergic pathways in the dentate gyrus of hippocampal slices from kainate-induced epileptic rats
    • Patrylo P.R., Dudek F.E. Physiological unmasking of new glutamatergic pathways in the dentate gyrus of hippocampal slices from kainate-induced epileptic rats. J. Neurophysiol. 79:1998;418-429.
    • (1998) J. Neurophysiol. , vol.79 , pp. 418-429
    • Patrylo, P.R.1    Dudek, F.E.2
  • 36
    • 0015309163 scopus 로고
    • Modification of seizure activity by electrical stimulation. II. Motor seizure
    • Racine R.J. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32:1972;281-294.
    • (1972) Electroencephalogr. Clin. Neurophysiol. , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 37
    • 0025220944 scopus 로고
    • Spontaneous sleep epilepsy in amygdala-kindled kittens: A preliminary report
    • Shouse M.N., Langer J.V., Dittes P.R. Spontaneous sleep epilepsy in amygdala-kindled kittens: a preliminary report. Brain Res. 535:1990;163-168.
    • (1990) Brain Res. , vol.535 , pp. 163-168
    • Shouse, M.N.1    Langer, J.V.2    Dittes, P.R.3
  • 38
    • 0026594823 scopus 로고
    • Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats
    • Sloviter R.S. Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats. Neurosci. Lett. 137:1992;91-96.
    • (1992) Neurosci. Lett. , vol.137 , pp. 91-96
    • Sloviter, R.S.1
  • 39
    • 0028359677 scopus 로고
    • The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy
    • Sloviter R.S. The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy. Ann. Neurol. 35:1994;640-654.
    • (1994) Ann. Neurol. , vol.35 , pp. 640-654
    • Sloviter, R.S.1
  • 40
    • 0031036451 scopus 로고    scopus 로고
    • Enhanced population responses in the basolateral amygdala of kainate-treated, epileptic rats in vitro
    • Smith B.N., Dudek F.E. Enhanced population responses in the basolateral amygdala of kainate-treated, epileptic rats in vitro. Neurosci. Lett. 222:1997;1-4.
    • (1997) Neurosci. Lett. , vol.222 , pp. 1-4
    • Smith, B.N.1    Dudek, F.E.2
  • 41
    • 0028109691 scopus 로고
    • Hippocampal resections and the use of human tissue in defining temporal lobe epilepsy syndromes
    • Spencer D.D., Spencer S.S. Hippocampal resections and the use of human tissue in defining temporal lobe epilepsy syndromes. Hippocampus. 4:1994;243-249.
    • (1994) Hippocampus , vol.4 , pp. 243-249
    • Spencer, D.D.1    Spencer, S.S.2
  • 42
    • 0019962803 scopus 로고
    • Electroclinical features of kainic acid-induced status epilepticus in freely moving cats. Microinjection into the dorsal hippocampus
    • Tanaka T., Kaijima M., Daita G., Ohgami S., Yonemasu Y., Riche D. Electroclinical features of kainic acid-induced status epilepticus in freely moving cats. Microinjection into the dorsal hippocampus. Electroencephalogr. Clin. Neurophysiol. 54:1982;288-300.
    • (1982) Electroencephalogr. Clin. Neurophysiol. , vol.54 , pp. 288-300
    • Tanaka, T.1    Kaijima, M.2    Daita, G.3    Ohgami, S.4    Yonemasu, Y.5    Riche, D.6
  • 43
    • 13244281798 scopus 로고
    • Experimental complex partial seizures induced by a microinjection of kainic acid into limbic structures
    • Tanaka T., Tanaka S., Fujita T., Takano K., Fukuda H., Sako K., Yonemasu Y. Experimental complex partial seizures induced by a microinjection of kainic acid into limbic structures. Prog. Neurobiol. 38:1992;317-334.
    • (1992) Prog. Neurobiol. , vol.38 , pp. 317-334
    • Tanaka, T.1    Tanaka, S.2    Fujita, T.3    Takano, K.4    Fukuda, H.5    Sako, K.6    Yonemasu, Y.7
  • 44
    • 0024510191 scopus 로고
    • Review: Cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: A novel experimental model of intractable epilepsy
    • Turski L., Ikonomido C., Turski W., Bortolotto Z., Cavalheiro E.A. Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy. Synapse. 3:1989;154-171.
    • (1989) Synapse , vol.3 , pp. 154-171
    • Turski, L.1    Ikonomido, C.2    Turski, W.3    Bortolotto, Z.4    Cavalheiro, E.A.5
  • 45
    • 0030557804 scopus 로고    scopus 로고
    • Chronic epilepsy with damage restricted to the hippocampus: Possible mechanisms
    • Wasterlain C.G., Shirasaka Y., Mazarati A.M., Spigelman I. Chronic epilepsy with damage restricted to the hippocampus: possible mechanisms. Epilepsy Res. 26:1996;255-265.
    • (1996) Epilepsy Res. , vol.26 , pp. 255-265
    • Wasterlain, C.G.1    Shirasaka, Y.2    Mazarati, A.M.3    Spigelman, I.4
  • 46
    • 0029937283 scopus 로고    scopus 로고
    • Electrographic seizures and new recurrent excitatory circuits in the dentate gyrus of hippocampal slices from kainate-treated epileptic rat
    • Wuarin J.-P., Dudek F.E. Electrographic seizures and new recurrent excitatory circuits in the dentate gyrus of hippocampal slices from kainate-treated epileptic rat. J. Neurosci. 16:1996;4438-4448.
    • (1996) J. Neurosci. , vol.16 , pp. 4438-4448
    • Wuarin, J.-P.1    Dudek, F.E.2


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