Influence of 2′-fluoro versus 2′-O-methyl substituent on the sugar puckering of 4′-c -aminomethyluridine

Journal of Organic Chemistry

Volumn 78, Issue 19, 2013, Pages 9956-9962

  Gore, Kiran R ^a   Harikrishna, S ^a   Pradeepkumar, P I ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY BOMBAY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL NATURE; COMPARATIVE STUDIES; CONFORMATIONAL ANALYSIS; DFT CALCULATION; HYDROGEN ATOMS; MODIFIED NUCLEOTIDES; MOLECULAR DYNAMICS SIMULATIONS; RNA MODIFICATIONS;

ATOMS; MOLECULAR DYNAMICS;

CONFORMATIONS;

METHYL GROUP; SUGAR; TRINUCLEOTIDE; URIDINE DERIVATIVE; 4' C AMINOMETHYL 2' DEOXY 2' FLUOROURIDINE; 4'-C-AMINOMETHYL-2'-DEOXY-2'-FLUOROURIDINE; DRUG DERIVATIVE; NUCLEOSIDE; NUCLEOTIDE; URIDINE;

ARTICLE; COMPARATIVE STUDY; CONFORMATION; DEACETYLATION; FLUORINATION; HYDROGEN BOND; MECHANICAL TORSION; MOLECULAR DYNAMICS; CHEMICAL STRUCTURE; CHEMISTRY; NUCLEOTIDE SEQUENCE; SYNTHESIS;

BASE SEQUENCE; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; NUCLEOSIDES; NUCLEOTIDES; URIDINE;

EID: 84885148976     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo4012333     Document Type: Article

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