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Volumn , Issue , 2013, Pages 325-335

Gastrointestinal and hepatoprotective effects of ocimum sanctum L: Syn (Holy Basil or Tulsi). Validation of the ethnomedicinal observation

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EID: 84885114576     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-397154-8.00039-7     Document Type: Chapter
Times cited : (10)

References (38)
  • 1
    • 34447539752 scopus 로고    scopus 로고
    • Effects of four indian medicinal herbs on isoniazid-rifampicin- and pyrazinamide-induced hepatic injury and immunosuppression in guinea pigs
    • Adhvaryu M.R., Reddy N., Parabia M.H. Effects of four indian medicinal herbs on isoniazid-rifampicin- and pyrazinamide-induced hepatic injury and immunosuppression in guinea pigs. World Journal of Gastroenterology 2007, 13:3199-3205.
    • (2007) World Journal of Gastroenterology , vol.13 , pp. 3199-3205
    • Adhvaryu, M.R.1    Reddy, N.2    Parabia, M.H.3
  • 2
    • 70449465144 scopus 로고    scopus 로고
    • Effect of carvacrol on hepatic marker enzymes and antioxidant status in D-galactosamine-induced hepatotoxicity in rats
    • Aristatile B., Al-Numair K.S., Veeramani C., Pugalendi K.V. Effect of carvacrol on hepatic marker enzymes and antioxidant status in D-galactosamine-induced hepatotoxicity in rats. Fundamental and Clinical Pharmacology 2009, 23:757-765.
    • (2009) Fundamental and Clinical Pharmacology , vol.23 , pp. 757-765
    • Aristatile, B.1    Al-Numair, K.S.2    Veeramani, C.3    Pugalendi, K.V.4
  • 4
    • 58149517977 scopus 로고    scopus 로고
    • Effects of leaves extract of Ocimum sanctum L. on arsenic-induced toxicity in Wistar albino rats
    • Banu S.G., Kumar G., Murugesan A.G. Effects of leaves extract of Ocimum sanctum L. on arsenic-induced toxicity in Wistar albino rats. Food and Chemical Toxicology 2009, 47:490-495.
    • (2009) Food and Chemical Toxicology , vol.47 , pp. 490-495
    • Banu, S.G.1    Kumar, G.2    Murugesan, A.G.3
  • 5
    • 79551560947 scopus 로고    scopus 로고
    • A study of certain herbs against chlorpyrifos-induced changes in lipid and protein profile in poultry
    • Bharathi P., Reddy A.G., Reddy A.R., Alpharaj M. A study of certain herbs against chlorpyrifos-induced changes in lipid and protein profile in poultry. Toxicology International 2011, 18:44-46.
    • (2011) Toxicology International , vol.18 , pp. 44-46
    • Bharathi, P.1    Reddy, A.G.2    Reddy, A.R.3    Alpharaj, M.4
  • 6
    • 78650131632 scopus 로고    scopus 로고
    • Reversal of cadmium-induced oxidative stress in chicken by herbal Adaptogens Withania Somnifera and Ocimum Sanctum
    • Bharavi K., Reddy A.G., Rao G.S., Reddy A.R., Rao S.V. Reversal of cadmium-induced oxidative stress in chicken by herbal Adaptogens Withania Somnifera and Ocimum Sanctum. Toxicology International 2010, 17:59-63.
    • (2010) Toxicology International , vol.17 , pp. 59-63
    • Bharavi, K.1    Reddy, A.G.2    Rao, G.S.3    Reddy, A.R.4    Rao, S.V.5
  • 8
    • 0000432273 scopus 로고
    • Hepatoprotective activity of Ocimum sanctum leaf extract against paracetamol induced hepatic damage in rats
    • Chattopadhyay R.R., Sarkar S.K., Ganguly S., Medda C., Basu T.K. Hepatoprotective activity of Ocimum sanctum leaf extract against paracetamol induced hepatic damage in rats. Indian Journal of Pharmacology 1992, 24:163-165.
    • (1992) Indian Journal of Pharmacology , vol.24 , pp. 163-165
    • Chattopadhyay, R.R.1    Sarkar, S.K.2    Ganguly, S.3    Medda, C.4    Basu, T.K.5
  • 9
    • 6544295992 scopus 로고    scopus 로고
    • Modulation of glutathione and antioxidant enzymes by Ocimum sanctum and its role in protection against radiation injury
    • Devi P.U., Ganasoundari A. Modulation of glutathione and antioxidant enzymes by Ocimum sanctum and its role in protection against radiation injury. Indian Journal of Experimental Biology 1999, 37:262-268.
    • (1999) Indian Journal of Experimental Biology , vol.37 , pp. 262-268
    • Devi, P.U.1    Ganasoundari, A.2
  • 12
    • 77952300961 scopus 로고    scopus 로고
    • Ursolic acid attenuates oxidative stress-mediated hepatocellular carcinoma induction by diethylnitrosamine in male Wistar rats
    • Gayathri R., Priya D.K., Gunassekaran G.R., Sakthisekaran D. Ursolic acid attenuates oxidative stress-mediated hepatocellular carcinoma induction by diethylnitrosamine in male Wistar rats. Asian Pacific Journal of Cancer Prevention 2009, 10:933-938.
    • (2009) Asian Pacific Journal of Cancer Prevention , vol.10 , pp. 933-938
    • Gayathri, R.1    Priya, D.K.2    Gunassekaran, G.R.3    Sakthisekaran, D.4
  • 13
    • 0035436460 scopus 로고    scopus 로고
    • Activity of Ocimum sanctum (the traditional Indian medicinal plant) against the enteric pathogens
    • Geeta Vasudevan D.M., Kedlaya R., Deepa S., Ballal M. Activity of Ocimum sanctum (the traditional Indian medicinal plant) against the enteric pathogens. Indian Journal of Medical Sciences 2001, 55(434-8):472.
    • (2001) Indian Journal of Medical Sciences , vol.55 , Issue.8-434 , pp. 472
    • Geeta, V.D.M.1    Kedlaya, R.2    Deepa, S.3    Ballal, M.4
  • 14
    • 23744474913 scopus 로고    scopus 로고
    • Effect of standardized extract of Ocimum sanctum Linn. on gastric mucosal offensive and defensive factors
    • Goel R.K., Sairam K., Dorababu M., Prabha T., Rao Ch.V. Effect of standardized extract of Ocimum sanctum Linn. on gastric mucosal offensive and defensive factors. Indian Journal of Experimental Biology 2005, 43:715-721.
    • (2005) Indian Journal of Experimental Biology , vol.43 , pp. 715-721
    • Goel, R.K.1    Sairam, K.2    Dorababu, M.3    Prabha, T.4    Rao, C.5
  • 15
    • 0036066981 scopus 로고    scopus 로고
    • Validation of traditional claim of Tulsi. Ocimum sanctum Linn. as a medicinal plant
    • Gupta S.K., Prakash J., Srivastava S. Validation of traditional claim of Tulsi. Ocimum sanctum Linn. as a medicinal plant. Indian Journal of Experimental Biology 2002, 40:765-773.
    • (2002) Indian Journal of Experimental Biology , vol.40 , pp. 765-773
    • Gupta, S.K.1    Prakash, J.2    Srivastava, S.3
  • 16
    • 33751174704 scopus 로고    scopus 로고
    • Antioxidant activity of hydroalcoholic leaf extract of Ocimum sanctum in animal models of peptic ulcer
    • Kath R.K., Gupta R.K. Antioxidant activity of hydroalcoholic leaf extract of Ocimum sanctum in animal models of peptic ulcer. Indian Journal of Physiology and Pharmacology 2006, 50:391-396.
    • (2006) Indian Journal of Physiology and Pharmacology , vol.50 , pp. 391-396
    • Kath, R.K.1    Gupta, R.K.2
  • 18
    • 0027439762 scopus 로고
    • Ocimum sanctum Linn-a study on gastric ulceration and gastric secretion in rats
    • Mandal S., Das D.N., De K., et al. Ocimum sanctum Linn-a study on gastric ulceration and gastric secretion in rats. Indian Journal of Physiology and Pharmacology 1993, 37:91-92.
    • (1993) Indian Journal of Physiology and Pharmacology , vol.37 , pp. 91-92
    • Mandal, S.1    Das, D.N.2    De, K.3
  • 19
    • 34848825651 scopus 로고    scopus 로고
    • Ocimum sanctum Linn. (Holy Basil) ethanolic leaf extract protects against 7, 12-dimethylbenz(a)anthracene-induced genotoxicity, oxidative stress, and imbalance in xenobiotic-metabolizing enzymes
    • Manikandan P., Murugan R.S., Abbas H., Abraham S.K., Nagini S. Ocimum sanctum Linn. (Holy Basil) ethanolic leaf extract protects against 7, 12-dimethylbenz(a)anthracene-induced genotoxicity, oxidative stress, and imbalance in xenobiotic-metabolizing enzymes. Journal of Medicinal Food 2007, 10:495-502.
    • (2007) Journal of Medicinal Food , vol.10 , pp. 495-502
    • Manikandan, P.1    Murugan, R.S.2    Abbas, H.3    Abraham, S.K.4    Nagini, S.5
  • 20
    • 77953609651 scopus 로고    scopus 로고
    • Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG
    • Manikandan P., Murugan R.S., Priyadarsini R.V., Vinothini G., Nagini S. Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG. Life Sciences 2010, 86:936-941.
    • (2010) Life Sciences , vol.86 , pp. 936-941
    • Manikandan, P.1    Murugan, R.S.2    Priyadarsini, R.V.3    Vinothini, G.4    Nagini, S.5
  • 21
    • 34547428891 scopus 로고    scopus 로고
    • Proliferation, angiogenesis and apoptosis-associated proteins are molecular targets for chemoprevention of MNNG-induced gastric carcinogenesis by ethanolic Ocimum sanctum leaf extract
    • Manikandan P., Vidjaya Letchoumy P., Prathiba D., Nagini S. Proliferation, angiogenesis and apoptosis-associated proteins are molecular targets for chemoprevention of MNNG-induced gastric carcinogenesis by ethanolic Ocimum sanctum leaf extract. Singapore Medical Journal 2007, 48:645-651.
    • (2007) Singapore Medical Journal , vol.48 , pp. 645-651
    • Manikandan, P.1    Vidjaya Letchoumy, P.2    Prathiba, D.3    Nagini, S.4
  • 22
    • 79151472984 scopus 로고    scopus 로고
    • Eugenol inhibits cell proliferation via NFκB suppression in a rat model of gastric carcinogenesis induced by MNNG
    • Manikandan P., Vinothini G., Vidya Priyadarsini R., Prathiba D., Nagini S. Eugenol inhibits cell proliferation via NFκB suppression in a rat model of gastric carcinogenesis induced by MNNG. Investigational New Drugs 2011, 29:110-117.
    • (2011) Investigational New Drugs , vol.29 , pp. 110-117
    • Manikandan, P.1    Vinothini, G.2    Vidya Priyadarsini, R.3    Prathiba, D.4    Nagini, S.5
  • 23
    • 0034940841 scopus 로고    scopus 로고
    • Pharmacological modification of endogenous antioxidant enzymes by ursolic acid on tetrachloride-induced liver damage in rats and primary cultures of rat hepatocytes
    • Martin-Aragón S., de las Heras B., Sanchez-Reus M.I., Benedi J. Pharmacological modification of endogenous antioxidant enzymes by ursolic acid on tetrachloride-induced liver damage in rats and primary cultures of rat hepatocytes. Experimental and Toxicologic Pathology 2001, 53:199-206.
    • (2001) Experimental and Toxicologic Pathology , vol.53 , pp. 199-206
    • Martin-Aragón, S.1    de las Heras, B.2    Sanchez-Reus, M.I.3    Benedi, J.4
  • 24
    • 0028198396 scopus 로고
    • Inhibition of microsomal lipid peroxidation and monooxygenase activities by eugenol
    • Nagababu E., Lakshmaiah N. Inhibition of microsomal lipid peroxidation and monooxygenase activities by eugenol. Free Radical Research 1994, 20:253-266.
    • (1994) Free Radical Research , vol.20 , pp. 253-266
    • Nagababu, E.1    Lakshmaiah, N.2
  • 25
    • 33845526601 scopus 로고    scopus 로고
    • Biochemical evaluation of antidiabetogenic properties of some commonly used Indian plants on streptozotocin-induced diabetes in experimental rats
    • Narendhirakannan R.T., Subramanian S., Kandaswamy M. Biochemical evaluation of antidiabetogenic properties of some commonly used Indian plants on streptozotocin-induced diabetes in experimental rats. Clinical and Experimental Pharmacology and Physiology 2006, 33:1150-1157.
    • (2006) Clinical and Experimental Pharmacology and Physiology , vol.33 , pp. 1150-1157
    • Narendhirakannan, R.T.1    Subramanian, S.2    Kandaswamy, M.3
  • 26
    • 84885102538 scopus 로고    scopus 로고
    • Evaluation of hepatosupression efficacy of Ocimum sanctum
    • Pingale S.S. Evaluation of hepatosupression efficacy of Ocimum sanctum. Journal of Pharmacy Research 2010, 3:1077-1081.
    • (2010) Journal of Pharmacy Research , vol.3 , pp. 1077-1081
    • Pingale, S.S.1
  • 27
    • 18744389453 scopus 로고    scopus 로고
    • Therapeutic uses of Ocimum sanctum Linn (Tulsi) with a note on eugenol and its pharmacological actions: a short review
    • Prakash P., Gupta N. Therapeutic uses of Ocimum sanctum Linn (Tulsi) with a note on eugenol and its pharmacological actions: a short review. Indian Journal of Physiology and Pharmacology 2005, 49:125-131.
    • (2005) Indian Journal of Physiology and Pharmacology , vol.49 , pp. 125-131
    • Prakash, P.1    Gupta, N.2
  • 28
    • 0032547132 scopus 로고    scopus 로고
    • Inhibition by an extract of Ocimum sanctum of DNA-binding activity of 7,12-dimethylbenz[a]anthracene in rat hepatocytes in vitro
    • Prashar R., Kumar A., Hewer A., Cole K.J., Davis W., Phillips D.H. Inhibition by an extract of Ocimum sanctum of DNA-binding activity of 7,12-dimethylbenz[a]anthracene in rat hepatocytes in vitro. Cancer Letters 1998, 128:155-160.
    • (1998) Cancer Letters , vol.128 , pp. 155-160
    • Prashar, R.1    Kumar, A.2    Hewer, A.3    Cole, K.J.4    Davis, W.5    Phillips, D.H.6
  • 29
    • 0031011354 scopus 로고    scopus 로고
    • Effect of Tulasi (Ocimum sanctum) leaf powder supplementation on blood sugar levels, serum lipids and tissue lipids in diabetic rats
    • Rai V., Iyer U., Mani U.V. Effect of Tulasi (Ocimum sanctum) leaf powder supplementation on blood sugar levels, serum lipids and tissue lipids in diabetic rats. Plant Foods for Human Nutrition 1997, 50:9-16.
    • (1997) Plant Foods for Human Nutrition , vol.50 , pp. 9-16
    • Rai, V.1    Iyer, U.2    Mani, U.V.3
  • 30
    • 77957273957 scopus 로고    scopus 로고
    • Antioxidant activities of hydroalcoholic extract of Ocimum sanctum against cadmium induced toxicity in rats
    • Ramesh B., Satakopan V.N. Antioxidant activities of hydroalcoholic extract of Ocimum sanctum against cadmium induced toxicity in rats. Indian Journal of Clinical Biochemistry 2006, 25:307-310.
    • (2006) Indian Journal of Clinical Biochemistry , vol.25 , pp. 307-310
    • Ramesh, B.1    Satakopan, V.N.2
  • 31
    • 29244460388 scopus 로고    scopus 로고
    • Protective effect of ursolic acid on ethanol-mediated experimental liver damage in rats
    • Saravanan R., Viswanathan P., Pugalendi K.V. Protective effect of ursolic acid on ethanol-mediated experimental liver damage in rats. Life Sciences 2006, 78:713-718.
    • (2006) Life Sciences , vol.78 , pp. 713-718
    • Saravanan, R.1    Viswanathan, P.2    Pugalendi, K.V.3
  • 32
    • 0036729653 scopus 로고    scopus 로고
    • Ocimum sanctum aqueous leaf extract provides protection against mercury induced toxicity in Swiss albino mice
    • Sharma M.K., Kumar M., Kumar A. Ocimum sanctum aqueous leaf extract provides protection against mercury induced toxicity in Swiss albino mice. Indian Journal of Experimental Biology 2002, 40:1079-1082.
    • (2002) Indian Journal of Experimental Biology , vol.40 , pp. 1079-1082
    • Sharma, M.K.1    Kumar, M.2    Kumar, A.3
  • 33
    • 0032962525 scopus 로고    scopus 로고
    • Evaluation of the gastric antiulcer activity of fixed oil of Ocimum sanctum (Holy Basil)
    • Singh S., Majumdar D.K. Evaluation of the gastric antiulcer activity of fixed oil of Ocimum sanctum (Holy Basil). Journal of Ethnopharmacology 1999, 65:13-19.
    • (1999) Journal of Ethnopharmacology , vol.65 , pp. 13-19
    • Singh, S.1    Majumdar, D.K.2
  • 37
    • 0347123324 scopus 로고    scopus 로고
    • Ethanolic extract of Ocimum sanctum leaves partially attenuates streptozotocin-induced alterations in glycogen content and carbohydrate metabolism in rats
    • Vats V., Yadav S.P., Grover J.K. Ethanolic extract of Ocimum sanctum leaves partially attenuates streptozotocin-induced alterations in glycogen content and carbohydrate metabolism in rats. Journal of Ethnopharmacology 2004, 90:155-160.
    • (2004) Journal of Ethnopharmacology , vol.90 , pp. 155-160
    • Vats, V.1    Yadav, S.P.2    Grover, J.K.3
  • 38
    • 76749164792 scopus 로고    scopus 로고
    • Investigation of antioxidant, anti-inflammatory and DNA-protective properties of eugenol in thioacetamide-induced liver injury in rats
    • Yogalakshmi B., Viswanathan P., Anuradha C.V. Investigation of antioxidant, anti-inflammatory and DNA-protective properties of eugenol in thioacetamide-induced liver injury in rats. Toxicology 2010, 268:204-212.
    • (2010) Toxicology , vol.268 , pp. 204-212
    • Yogalakshmi, B.1    Viswanathan, P.2    Anuradha, C.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.