Ocimum sanctum Linn. (Holy Basil) ethanolic leaf extract protects against 7,12-dimethylbenz[a]anthracene-induced genotoxicity, oxidative stress, and imbalance in xenobiotic-metabolizing enzymes

Journal of Medicinal Food

Volumn 10, Issue 3, 2007, Pages 495-502

  Manikandan, P ^a   Senthil Murugan, R ^a   Abbas, H ^a   Abraham, S K ^b   Nagini, S ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

7,12 dimethylbenz a anthracene; Antioxidants; Chemoprevention; Lipid peroxidation; Micronuclei; Ocimum sanctum; Xenobiotic metabolizing enzymes

Indexed keywords

CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME B5; CYTOCHROME P450; DIMETHYLBENZ[A]ANTHRACENE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; MANGANESE SUPEROXIDE DISMUTASE; OCIMUM SANCTUM EXTRACT; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASIL; BONE MARROW; CONTROLLED STUDY; DRUG DOSE COMPARISON; ENZYME ACTIVITY; GENOTOXICITY; HEMOLYSATE; LIPID PEROXIDATION; LIVER; MALE; MICRONUCLEUS TEST; NONHUMAN; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT LEAF; PRIORITY JOURNAL; RAT; XENOBIOTIC METABOLISM;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ANTIOXIDANTS; BONE MARROW; CARRIER PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; HEMEPROTEINS; LIPID PEROXIDATION; MALE; MUTATION; OCIMUM; OXIDATIVE STRESS; PLANT EXTRACTS; PLANT LEAVES; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; XENOBIOTICS;

OCIMUM TENUIFLORUM; RATTUS NORVEGICUS;

EID: 34848825651     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2006.125     Document Type: Article

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