Blockade of interleukin 6 signaling improves the survival rate of transplanted bone marrow stromal cells and increases locomotor function in mice with spinal cord injury

Journal of Neuropathology and Experimental Neurology

Volumn 72, Issue 10, 2013, Pages 980-993

  Tan, Ying ^a,b   Uchida, Kenzo ^b   Nakajima, Hideaki ^b   Guerrero, Alexander R ^b   Watanabe, Shuji ^b   Hirai, Takayuki ^b   Takeura, Naoto ^b   Liu, Shao Yu ^a   Johnson, William E B ^c   Baba, Hisatoshi ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF FUKUI   (Japan)

^c ASTON UNIVERSITY   (United Kingdom)

Author keywords

Apoptosis; Bone marrow stromal cells; Cell survival; Inflammation; Interleukin 6; Spinal cord injury; Transplantation

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE 1; MR 16 1; MR 16 1 ANTIBODY; NEUROTROPHIC FACTOR; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASTROCYTE; BONE MARROW CELL; BRAIN CONTUSION; COMPARATIVE STUDY; CONTROLLED STUDY; LOCOMOTION; MALE; MESENCHYMAL STROMA CELL; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; SPINAL CORD INJURY; SURVIVAL RATE;

ANIMALS; CELL SURVIVAL; DISEASE MODELS, ANIMAL; INTERLEUKIN-6; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE; MOTOR ACTIVITY; NEURONS; RECEPTORS, INTERLEUKIN-6; RECOVERY OF FUNCTION; SIGNAL TRANSDUCTION; SPINAL CORD INJURIES; SURVIVAL RATE;

EID: 84885079485     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0b013e3182a79de9     Document Type: Article

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