SDF-1α inhibits hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells through PI3K/Akt and ERK1/2 signaling pathways

Molecular Biology Reports

Volumn 38, Issue 1, 2011, Pages 9-16

  Yin, Qi ^a,b   Jin, Peifeng ^b   Liu, Xuebin ^c   Wei, Hua ^a   Lin, Xiaoming ^b   Chi, Chuang ^b   Liu, Yu ^b   Sun, Chengchao ^b   Wei, Yingjie ^a  

^a BEIJING HOSPITAL   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c GENERAL HOSPITAL OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

Author keywords

Apoptosis; Hypoxia SD; MSCs; SDF 1 ; Signaling pathways

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CASPASE 3; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STROMAL CELL DERIVED FACTOR 1ALPHA; WORTMANNIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL HYPOXIA; CELL PROTECTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME RELEASE; HEMATOPOIETIC STEM CELL; MALE; MESENCHYMAL STEM CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; NONHUMAN; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CASPASE 3; CELL HYPOXIA; CHEMOKINE CXCL12; CULTURE MEDIA, SERUM-FREE; CYTOPROTECTION; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MESENCHYMAL STEM CELLS; MITOCHONDRIA; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY;

EID: 78651107612     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-0071-9     Document Type: Article

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