메뉴 건너뛰기




Volumn 15, Issue 10, 2013, Pages 1366-1378

Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme

Author keywords

Dll4 Notch signaling; macrophage microglia; microvascular density; primary glioblastoma multiforme; vascular pattern

Indexed keywords

LAMININ; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; NOTCH RECEPTOR; NOTCH4 RECEPTOR; VASCULOTROPIN;

EID: 84885011140     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/not071     Document Type: Article
Times cited : (46)

References (71)
  • 2
    • 0032445251 scopus 로고    scopus 로고
    • Survival rates for primary malignant brain tumours in Europe
    • DOI 10.1016/S0959-8049(98)00336-0, PII S0959804998003360
    • Sant M, van der Sanden G, Capocaccia R. Survival rates for primary malignant brain tumours in Europe. Eur J Cancer. 1998;34(14):2241-2247. (Pubitemid 29036893)
    • (1998) European Journal of Cancer , vol.34 , Issue.14 , pp. 2241-2247
    • Sant, M.1    Van Der Sanden, G.2    Capocaccia, R.3
  • 4
    • 14244265590 scopus 로고    scopus 로고
    • Epidemiology and etiology of gliomas
    • DOI 10.1007/s00401-005-0991-y
    • Ohgaki H, Kleihues P. Epidemiology and etiology of gliomas. Acta Neuropathol. 2005;109(1):93-108. (Pubitemid 40287792)
    • (2005) Acta Neuropathologica , vol.109 , Issue.1 , pp. 93-108
    • Ohgaki, H.1    Kleihues, P.2
  • 5
    • 9144232309 scopus 로고    scopus 로고
    • Molecular mechanisms of glioma cell migration and invasion
    • DOI 10.1007/s11060-004-2751-6
    • DemuthT, BerensME.Molecularmechanisms of glioma cell migration and invasion. J Neurooncol. 2004;70(2):217-228. (Pubitemid 39545733)
    • (2004) Journal of Neuro-Oncology , vol.70 , Issue.2 , pp. 217-228
    • Demuth, T.1    Berens, M.E.2
  • 8
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • DOI 10.1126/science.284.5415.770
    • Artavanis-Tsakonas S, RandMD, Lake RJ. Notch signaling: cell fate control and signal integrationin development. Science. 1999;284(5415):770-776. (Pubitemid 29291335)
    • (1999) Science , vol.284 , Issue.5415 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 9
    • 0032996755 scopus 로고    scopus 로고
    • Humanligands of theNotch receptor
    • Gray GE,MannRS, Mitsiadis E, et al.Humanligands of theNotch receptor. Am J Pathol. 1999;154(3):785-794.
    • (1999) Am J Pathol , vol.154 , Issue.3 , pp. 785-794
    • Gray, G.E.1    Mann, R.S.2    Mitsiadis, E.3
  • 11
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: Multiple effectors of the Notch signaling pathway
    • DOI 10.1002/jcp.10208
    • Iso T, Kedes L, Hamamori Y. HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol. 2003;194(3):237-255. (Pubitemid 36176887)
    • (2003) Journal of Cellular Physiology , vol.194 , Issue.3 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 13
    • 61949381850 scopus 로고    scopus 로고
    • Building a vessel wall with notch signaling
    • Regan JN, MajeskyMW. Building a vessel wall with notch signaling. Circ Res. 2009;104(4):419-421.
    • (2009) Circ Res , vol.104 , Issue.4 , pp. 419-421
    • Regan, J.N.1    Majesky, M.W.2
  • 15
    • 34250867977 scopus 로고    scopus 로고
    • Notch signaling in development and cancer
    • DOI 10.1210/er.2006-0046
    • Bolos V, Grego-Bessa J, de la Pompa JL. Notch signaling in development and cancer. Endocr Rev. 2007;28(3):339-363. (Pubitemid 46984831)
    • (2007) Endocrine Reviews , vol.28 , Issue.3 , pp. 339-363
    • Bolos, V.1    Grego-Bessa, J.2    De La Pompa, J.L.3
  • 16
    • 38549148417 scopus 로고    scopus 로고
    • Notch and cancer: A double-edged sword
    • DOI 10.1007/s00018-007-7164-1
    • Koch U, Radtke F. Notch and cancer: a double-edged sword. Cell Mol Life Sci. 2007;64(21):2746-2762. (Pubitemid 351152259)
    • (2007) Cellular and Molecular Life Sciences , vol.64 , Issue.21 , pp. 2746-2762
    • Koch, U.1    Radtke, F.2
  • 17
    • 35748972639 scopus 로고    scopus 로고
    • NOTCH and PI3K-AKT pathways intertwined
    • DOI 10.1016/j.ccr.2007.10.027, PII S1535610807003066
    • Gutierrez A, Look AT. NOTCH and PI3K-AKT pathways intertwined. Cancer Cell. 2007;12(5):411-413. (Pubitemid 350046412)
    • (2007) Cancer Cell , vol.12 , Issue.5 , pp. 411-413
    • Gutierrez, A.1    Look, A.T.2
  • 18
    • 0034738965 scopus 로고    scopus 로고
    • Ras pathway signals are required for notch-mediated oncogenesis
    • Fitzgerald K, Harrington A, Leder P. Ras pathway signals are required for notch-mediated oncogenesis. Oncogene. 2000;19(37):4191-4198.
    • (2000) Oncogene , vol.19 , Issue.37 , pp. 4191-4198
    • Fitzgerald, K.1    Harrington, A.2    Leder, P.3
  • 19
    • 53049085101 scopus 로고    scopus 로고
    • Oncogenic NOTCH1 control of MYC and PI3K: Challenges and opportunities for anti-NOTCH1 therapy in T-cell acute lymphoblastic leukemias and lymphomas
    • Palomero T, Ferrando A. Oncogenic NOTCH1 control of MYC and PI3K: challenges and opportunities for anti-NOTCH1 therapy in T-cell acute lymphoblastic leukemias and lymphomas. Clin Cancer Res. 2008;14(17):5314-5317.
    • (2008) Clin Cancer Res , vol.14 , Issue.17 , pp. 5314-5317
    • Palomero, T.1    Ferrando, A.2
  • 20
    • 43549123531 scopus 로고    scopus 로고
    • The role of the PTEN/AKT pathway in NOTCH1-induced leukemia
    • Palomero T, Dominguez M, Ferrando AA. The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia. Cell Cycle. 2008;7(8): 965-970. (Pubitemid 351679827)
    • (2008) Cell Cycle , vol.7 , Issue.8 , pp. 965-970
    • Palomero, T.1    Dominguez, M.2    Ferrando, A.A.3
  • 21
    • 84856505322 scopus 로고    scopus 로고
    • Notch1 promotes glioma cell migration and invasion by stimulating beta-catenin and NF-kappaB signaling via AKT activation
    • Zhang X, Chen T, Zhang J, et al. Notch1 promotes glioma cell migration and invasion by stimulating beta-catenin and NF-kappaB signaling via AKT activation. Cancer Sci. 2012;103(2):181-190.
    • (2012) Cancer Sci , vol.103 , Issue.2 , pp. 181-190
    • Zhang, X.1    Chen, T.2    Zhang, J.3
  • 22
    • 34247539127 scopus 로고    scopus 로고
    • The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth
    • DOI 10.1038/nrc2130, PII NRC2130
    • Thurston G, Noguera-Troise I, Yancopoulos GD. The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth. Nat Rev Cancer. 2007;7(5):327-331. (Pubitemid 46652486)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.5 , pp. 327-331
    • Thurston, G.1    Noguera-Troise, I.2    Yancopoulos, G.D.3
  • 23
    • 75849133698 scopus 로고    scopus 로고
    • The functional role of Notch signaling in human gliomas
    • StockhausenMT, Kristoffersen K, Poulsen HS.The functional role of Notch signaling in human gliomas. Neuro Oncol 2010 12 (2) 199-211.
    • (2010) Neuro Oncol , vol.12 , Issue.2 , pp. 199-211
    • Stockhausen, M.T.1    Kristoffersen, K.2    Poulsen, H.S.3
  • 24
    • 56049092014 scopus 로고    scopus 로고
    • Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms
    • DOI 10.1016/j.gde.2008.07.013, PII S0959437X08000920
    • Poellinger L, LendahlU. Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms. Curr Opin Genet Dev. 2008;18(5): 449-454. (Pubitemid 50260912)
    • (2008) Current Opinion in Genetics and Development , vol.18 , Issue.5 , pp. 449-454
    • Poellinger, L.1    Lendahl, U.2
  • 26
    • 0035753241 scopus 로고    scopus 로고
    • Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis
    • Mailhos C, Modlich U, Lewis J, Harris A, Bicknell R, Ish-Horowicz D. Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation. 2001;69(2-3): 135-144. (Pubitemid 33755062)
    • (2001) Differentiation , vol.69 , Issue.2-3 , pp. 135-144
    • Mailhos, C.1    Modlich, U.2    Lewis, J.3    Harris, A.4    Bicknell, R.5    Ish-Horowicz, D.6
  • 27
    • 82655164839 scopus 로고    scopus 로고
    • Dll4-Notch signaling as a therapeutic target in tumor angiogenesis
    • Kuhnert F, Kirshner JR, Thurston G. Dll4-Notch signaling as a therapeutic target in tumor angiogenesis. Vasc Cell. 2011;3(1):20.
    • (2011) Vasc Cell , vol.3 , Issue.1 , pp. 20
    • Kuhnert, F.1    Kirshner, J.R.2    Thurston, G.3
  • 30
    • 84858998140 scopus 로고    scopus 로고
    • Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma
    • Jubb AM, Browning L, Campo L, et al. Expression of vascular Notch ligands Delta-like 4 and Jagged-1 in glioblastoma. Histopathology. 2012;60(5):740-747.
    • (2012) Histopathology , vol.60 , Issue.5 , pp. 740-747
    • Jubb, A.M.1    Browning, L.2    Campo, L.3
  • 31
    • 84861111256 scopus 로고    scopus 로고
    • The contribution of Notch signaling to glioblastoma via activation of cancer stem cell self-renewal: The role of the endothelial network
    • Gursel DB, Berry N, Boockvar JA. The contribution of Notch signaling to glioblastoma via activation of cancer stem cell self-renewal: the role of the endothelial network. Neurosurgery. 2012;70(2):N19-N21.
    • (2012) Neurosurgery , vol.70 , Issue.2
    • Gursel, D.B.1    Berry, N.2    Boockvar, J.A.3
  • 32
    • 77950855517 scopus 로고    scopus 로고
    • Expression of the transcription factor HEY1 in glioblastoma: A preliminary clinical study
    • Gaetani P, Hulleman E, Levi D, et al. Expression of the transcription factor HEY1 in glioblastoma: a preliminary clinical study. Tumori. 2010;96(1):97-102.
    • (2010) Tumori , vol.96 , Issue.1 , pp. 97-102
    • Gaetani, P.1    Hulleman, E.2    Levi, D.3
  • 33
    • 0030033781 scopus 로고    scopus 로고
    • Prognostic significance of preoperative MRI scans in glioblastoma multiforme
    • DOI 10.1007/BF00146086
    • Hammoud MA, Sawaya R, Shi W, Thall PF, Leeds NE. Prognostic significance of preoperative MRI scans in glioblastoma multiforme. J Neurooncol. 1996;27(1):65-73. (Pubitemid 26052641)
    • (1996) Journal of Neuro-Oncology , vol.27 , Issue.1 , pp. 65-73
    • Hammoud, M.A.1
  • 34
    • 84864287630 scopus 로고    scopus 로고
    • Glioblastoma: Clinical characteristics, prognostic factors and survival in 492 patients
    • Stark AM, van de Bergh J, Hedderich J, Mehdorn HM, Nabavi A. Glioblastoma: clinical characteristics, prognostic factors and survival in 492 patients. Clin Neurol Neurosurg. 2012;114(7):840-845.
    • (2012) Clin Neurol Neurosurg , vol.114 , Issue.7 , pp. 840-845
    • Stark, A.M.1    Van De Bergh, J.2    Hedderich, J.3    Mehdorn, H.M.4    Nabavi, A.5
  • 35
    • 0035829691 scopus 로고    scopus 로고
    • Silencing of HTR1B and reduced expression of EDN1 in human lung cancers, revealed by methylation-sensitive representational difference analysis
    • DOI 10.1038/sj.onc.1204940
    • Takai D, Yagi Y, Wakazono K, et al. Silencing of HTR1B and reduced expression of EDN1 in human lung cancers, revealed by methylationsensitive representational difference analysis. Oncogene. 2001;20(51): 7505-7513. (Pubitemid 33086910)
    • (2001) Oncogene , vol.20 , Issue.51 , pp. 7505-7513
    • Takai, D.1    Yagi, Y.2    Wakazono, K.3    Ohishi, N.4    Morita, Y.5    Sugimura, T.6    Ushijima, T.7
  • 36
    • 11144349554 scopus 로고    scopus 로고
    • Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors
    • DOI 10.1002/ijc.20575
    • MollemannM,Wolter M, Felsberg J, Collins VP, Reifenberger G. Frequent promoter hypermethylation and low expression of theMGMTgene in oligodendroglial tumors. Int J Cancer. 2005;113(3):379-385. (Pubitemid 40038704)
    • (2005) International Journal of Cancer , vol.113 , Issue.3 , pp. 379-385
    • Mollemann, M.1    Wolter, M.2    Felsberg, J.3    Collins, V.P.4    Reifenberger, G.5
  • 37
    • 58949089716 scopus 로고    scopus 로고
    • AMDR1(ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients
    • Schaich M, Kestel L, Pfirrmann M, et al. AMDR1(ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients. Ann Oncol. 2009;20(1):175-181.
    • (2009) Ann Oncol , vol.20 , Issue.1 , pp. 175-181
    • Schaich, M.1    Kestel, L.2    Pfirrmann, M.3
  • 38
    • 44949231424 scopus 로고    scopus 로고
    • T method
    • DOI 10.1038/nprot.2008.73, PII NPROT.2008.73
    • Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc. 2008;3(6):1101-1108. (Pubitemid 351818697)
    • (2008) Nature Protocols , vol.3 , Issue.6 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 39
    • 0029127219 scopus 로고
    • Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors
    • Weidner N. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat. 1995;36(2):169-180.
    • (1995) Breast Cancer Res Treat , vol.36 , Issue.2 , pp. 169-180
    • Weidner, N.1
  • 40
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma
    • Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med. 1991;324(1):1-8.
    • (1991) N Engl J Med , vol.324 , Issue.1 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 41
    • 37549012177 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (Cox-2) expression and angiogenesis in glioblastoma
    • Onguru O, Gamsizkan M, Ulutin C, Gunhan O. Cyclooxygenase-2 (Cox-2) expression and angiogenesis in glioblastoma. Neuropathology. 2008;28(1):29-34.
    • (2008) Neuropathology , vol.28 , Issue.1 , pp. 29-34
    • Onguru, O.1    Gamsizkan, M.2    Ulutin, C.3    Gunhan, O.4
  • 43
    • 4544265972 scopus 로고    scopus 로고
    • Algorithm for the standardized assessment of vascular patterns in glioblastoma specimens
    • Preusser M, Birner P, Hainfellner JA. Algorithm for the standardized assessment of vascular patterns in glioblastoma specimens. Clin Neuropathol. 2004;23(5):238-240. (Pubitemid 39222715)
    • (2004) Clinical Neuropathology , vol.23 , Issue.5 , pp. 238-240
    • Preusser, M.1    Birner, P.2    Hainfellner, J.A.3
  • 44
    • 77950560825 scopus 로고    scopus 로고
    • Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer
    • Jubb AM, Soilleux EJ, Turley H, et al. Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer. Am J Pathol. 2010;176(4):2019-2028.
    • (2010) Am J Pathol , vol.176 , Issue.4 , pp. 2019-2028
    • Jubb, A.M.1    Soilleux, E.J.2    Turley, H.3
  • 45
    • 70449517334 scopus 로고    scopus 로고
    • Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer
    • Jubb AM, Turley H, Moeller HC, et al. Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer. Br J Cancer. 2009;101(10):1749- 1757.
    • (2009) Br J Cancer , vol.101 , Issue.10 , pp. 1749-1757
    • Jubb, A.M.1    Turley, H.2    Moeller, H.C.3
  • 47
    • 79952715824 scopus 로고    scopus 로고
    • Inhibition of Notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres
    • Chen J, Kesari S, Rooney C, et al. Inhibition of Notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. Genes Cancer. 2010;1(8):822-835.
    • (2010) Genes Cancer , vol.1 , Issue.8 , pp. 822-835
    • Chen, J.1    Kesari, S.2    Rooney, C.3
  • 48
    • 84857830005 scopus 로고    scopus 로고
    • Identification and functional validation of CDH11, PCSK6 and SH3GL3 as novel glioma invasion-associated candidate genes
    • Delic S, Lottmann N, Jetschke K, Reifenberger G, Riemenschneider MJ. Identification and functional validation of CDH11, PCSK6 and SH3GL3 as novel glioma invasion-associated candidate genes. Neuropathol Appl Neurobiol. 2012;38(2):201-212.
    • (2012) Neuropathol Appl Neurobiol , vol.38 , Issue.2 , pp. 201-212
    • Delic, S.1    Lottmann, N.2    Jetschke, K.3    Reifenberger, G.4    Riemenschneider, M.J.5
  • 51
    • 25444506836 scopus 로고    scopus 로고
    • Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
    • DOI 10.1158/0008-5472.CAN-05-1208
    • Patel NS, Li JL, Generali D, Poulsom R, Cranston DW, Harris AL. Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function. Cancer Res. 2005;65(19):8690- 8697. (Pubitemid 41377356)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8690-8697
    • Patel, N.S.1    Li, J.-L.2    Generali, D.3    Poulsom, R.4    Cranston, D.W.5    Harris, A.L.6
  • 52
    • 80052803473 scopus 로고    scopus 로고
    • DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo
    • Li JL, Sainson RC, Oon CE, et al. DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo. Cancer Res. 2011;71(18):6073-6083.
    • (2011) Cancer Res , vol.71 , Issue.18 , pp. 6073-6083
    • Li, J.L.1    Sainson, R.C.2    Oon, C.E.3
  • 53
    • 84861974104 scopus 로고    scopus 로고
    • Cross-talk between endothelial cells and tumor via delta-like ligand 4/Notch/PTEN signaling inhibits lung cancer growth
    • Ding XY, Ding J, Wu K, et al. Cross-talk between endothelial cells and tumor via delta-like ligand 4/Notch/PTEN signaling inhibits lung cancer growth. Oncogene. 2012;31(23):2899-2906.
    • (2012) Oncogene , vol.31 , Issue.23 , pp. 2899-2906
    • Ding, X.Y.1    Ding, J.2    Wu, K.3
  • 54
    • 84865160657 scopus 로고    scopus 로고
    • HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRbeta-selected mouse thymocytes
    • Wong GW, Knowles GC, Mak TW, Ferrando AA, Zuniga-Pflucker JC. HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRbeta-selected mouse thymocytes. Blood. 2012;120(7):1439-1448.
    • (2012) Blood , vol.120 , Issue.7 , pp. 1439-1448
    • Wong, G.W.1    Knowles, G.C.2    Mak, T.W.3    Ferrando, A.A.4    Zuniga-Pflucker, J.C.5
  • 55
    • 55749093799 scopus 로고    scopus 로고
    • Antiangiogenic therapy in malignant gliomas
    • Norden AD, Drappatz J, Wen PY. Antiangiogenic therapy in malignant gliomas. Curr Opin Oncol. 2008;20(6):652-661.
    • (2008) Curr Opin Oncol , vol.20 , Issue.6 , pp. 652-661
    • Norden, A.D.1    Drappatz, J.2    Wen, P.Y.3
  • 56
    • 70449517400 scopus 로고    scopus 로고
    • Antiangiogenic therapies for high-grade glioma
    • Norden AD, Drappatz J,Wen PY. Antiangiogenic therapies for high-grade glioma. Nat Rev Neurol. 2009;5(11):610-620.
    • (2009) Nat Rev Neurol , vol.5 , Issue.11 , pp. 610-620
    • Norden, A.D.1    Drappatz, J.2    Wen, P.Y.3
  • 57
    • 33745298443 scopus 로고    scopus 로고
    • Histopathologic assessment of hot-spot microvessel density and vascular patterns in glioblastoma: Poor observer agreement limits clinical utility as prognostic factors - A translational research project of the European Organization for Research and Treatment of Cancer Brain Tumor Group
    • DOI 10.1002/cncr.21973
    • Preusser M, Heinzl H, Gelpi E, et al. Histopathologic assessment of hot-spot microvessel density and vascular patterns in glioblastoma: Poor observer agreement limits clinical utility as prognostic factors: a translational research project of the European Organization for Research and Treatment of Cancer Brain Tumor Group. Cancer. 2006;107(1):162-170. (Pubitemid 43939043)
    • (2006) Cancer , vol.107 , Issue.1 , pp. 162-170
    • Preusser, M.1    Heinzl, H.2    Gelpi, E.3    Schonegger, K.4    Haberler, C.5    Birner, P.6    Marosi, C.7    Hegi, M.8    Gorlia, T.9    Hainfellner, J.A.10
  • 58
    • 74049090120 scopus 로고    scopus 로고
    • Concerns about antiangiogenic treatment in patients with glioblastoma multiforme
    • Verhoeff JJ, van Tellingen O, Claes A, et al. Concerns about antiangiogenic treatment in patients with glioblastoma multiforme. BMC Cancer. 2009;9:444.
    • (2009) BMC Cancer , vol.9 , pp. 444
    • Verhoeff, J.J.1    Van Tellingen, O.2    Claes, A.3
  • 60
    • 0029781336 scopus 로고    scopus 로고
    • Distribution and characterization of microglia/macrophages in human brain tumors
    • DOI 10.1007/s004010050520
    • Roggendorf W, Strupp S, Paulus W. Distribution and characterization of microglia/macrophages in human brain tumors. Acta Neuropathol. 1996;92(3):288-293. (Pubitemid 26278960)
    • (1996) Acta Neuropathologica , vol.92 , Issue.3 , pp. 288-293
    • Roggendorf, W.1    Strupp, S.2    Paulus, W.3
  • 61
    • 78751700548 scopus 로고    scopus 로고
    • Microglia/macrophages promote glioma progression
    • Zhai H, Heppner FL, Tsirka SE. Microglia/macrophages promote glioma progression. Glia. 2011;59(3):472-485.
    • (2011) Glia , vol.59 , Issue.3 , pp. 472-485
    • Zhai, H.1    Heppner, F.L.2    Tsirka, S.E.3
  • 62
    • 41349091447 scopus 로고    scopus 로고
    • Glioma cells on the run - The migratory transcriptome of 10 human glioma cell lines
    • Demuth T, Rennert JL, Hoelzinger DB, et al. Glioma cells on the run - the migratory transcriptome of 10 human glioma cell lines. BMC Genomics. 2008;9:54.
    • (2008) BMC Genomics , vol.9 , pp. 54
    • Demuth, T.1    Rennert, J.L.2    Hoelzinger, D.B.3
  • 64
    • 77749321234 scopus 로고    scopus 로고
    • Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappaB signaling pathways
    • Wang Z, Li Y, Banerjee S, et al. Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappaB signaling pathways. J Cell Biochem. 2010;109(4):726-736.
    • (2010) J Cell Biochem , vol.109 , Issue.4 , pp. 726-736
    • Wang, Z.1    Li, Y.2    Banerjee, S.3
  • 66
    • 66349117115 scopus 로고    scopus 로고
    • Prognostic and predictive factors for gliomas in adults
    • Frenel JS, Botti M, Loussouarn D, Campone M. [Prognostic and predictive factors for gliomas in adults]. Bull Cancer. 2009;96(4):357-367.
    • (2009) Bull Cancer , vol.96 , Issue.4 , pp. 357-367
    • Frenel, J.S.1    Botti, M.2    Loussouarn, D.3    Campone, M.4
  • 68
    • 0030279844 scopus 로고    scopus 로고
    • Glioblastoma multiforme: Radiologic-pathologic correlation
    • quiz 1462-1413
    • Rees JH, Smirniotopoulos JG, Jones RV, Wong K. Glioblastoma multiforme: radiologic-pathologic correlation. Radiographics. 1996; 16(6):1413-1438; quiz 1462-1413.
    • (1996) Radiographics , vol.16 , Issue.6 , pp. 1413-1438
    • Rees, J.H.1    Smirniotopoulos, J.G.2    Jones, R.V.3    Wong, K.4
  • 69
    • 34047260282 scopus 로고    scopus 로고
    • Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: Insights from a mathematical model
    • DOI 10.1158/0008-5472.CAN-06-4102
    • Jain RK, Tong RT, Munn LL. Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model. Cancer Res. 2007;67(6):2729-2735. (Pubitemid 46548961)
    • (2007) Cancer Research , vol.67 , Issue.6 , pp. 2729-2735
    • Jain, R.K.1    Tong, R.T.2    Munn, L.L.3
  • 71
    • 78149478057 scopus 로고    scopus 로고
    • MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib
    • Chahal M, Xu Y, Lesniak D, et al. MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib. Neuro Oncol. 2010;12(8):822-833.
    • (2010) Neuro Oncol , vol.12 , Issue.8 , pp. 822-833
    • Chahal, M.1    Xu, Y.2    Lesniak, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.