메뉴 건너뛰기




Volumn 31, Issue 23, 2012, Pages 2899-2906

Cross-talk between endothelial cells and tumor via delta-like ligand4/Notch/PTEN signaling inhibits lung cancer growth

Author keywords

delta like ligand 4; lung cancer; Notch; PTEN; vascular endothelial cells

Indexed keywords

DELTA LIKE LIGAND 4; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RECOMBINANT PROTEIN; RNA; UNCLASSIFIED DRUG;

EID: 84861974104     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.467     Document Type: Article
Times cited : (40)

References (37)
  • 1
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • DOI 10.1126/science.284.5415.770
    • Artavanis-Tsakonas S, Rand MD, Lake RJ. (1999). Notch signaling: cell fate control and signal integration in development. Science 284: 770-776. (Pubitemid 29291335)
    • (1999) Science , vol.284 , Issue.5415 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 2
    • 66449123068 scopus 로고    scopus 로고
    • The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis
    • Benedito R, Roca C, Sorensen I, Adams S, Gossler A, Fruttiger M et al. (2009). The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell 137: 1124-1135.
    • (2009) Cell , vol.137 , pp. 1124-1135
    • Benedito, R.1    Roca, C.2    Sorensen, I.3    Adams, S.4    Gossler, A.5    Fruttiger, M.6
  • 3
    • 34548599785 scopus 로고    scopus 로고
    • Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung
    • DOI 10.1158/0008-5472.CAN-07-1229
    • Chen Y, De Marco MA, Graziani I, Gazdar AF, Strack PR, Miele L et al. (2007). Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung. Cancer Res 67: 7954-7959. (Pubitemid 47395124)
    • (2007) Cancer Research , vol.67 , Issue.17 , pp. 7954-7959
    • Chen, Y.1    De Marco, M.A.2    Graziani, I.3    Gazdar, A.F.4    Strack, P.R.5    Miele, L.6    Bocchetta, M.7
  • 4
    • 3342979755 scopus 로고    scopus 로고
    • Notch in lung development and lung cancer
    • DOI 10.1016/j.semcancer.2004.04.015, PII S1044579X0400032X
    • Collins BJ, Kleeberger W, Ball DW. (2004). Notch in lung development and lung cancer. Semin Cancer Biol 14: 357-364. (Pubitemid 38993637)
    • (2004) Seminars in Cancer Biology , vol.14 , Issue.5 , pp. 357-364
    • Collins, B.J.1    Kleeberger, W.2    Ball, D.W.3
  • 5
    • 0034011914 scopus 로고    scopus 로고
    • Notch signaling in T cell development
    • DOI 10.1016/S0952-7915(99)00067-9
    • Deftos ML, Bevan MJ. (2000). Notch signaling in T cell development. Curr Opin Immunol 12: 166-172. (Pubitemid 30133104)
    • (2000) Current Opinion in Immunology , vol.12 , Issue.2 , pp. 166-172
    • Deftos, M.L.1    Bevan, M.J.2
  • 6
    • 67650844443 scopus 로고    scopus 로고
    • The new lung cancer staging system
    • Detterbeck FC, Boffa DJ, Tanoue LT. (2009). The new lung cancer staging system. Chest 136: 260-271.
    • (2009) Chest , vol.136 , pp. 260-271
    • Detterbeck, F.C.1    Boffa, D.J.2    Tanoue, L.T.3
  • 7
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. (1971). Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 8
    • 65549121943 scopus 로고    scopus 로고
    • Notch signaling: The core pathway and its posttranslational regulation
    • Fortini ME. (2009). Notch signaling: the core pathway and its posttranslational regulation. Dev Cell 16: 633-647.
    • (2009) Dev Cell , vol.16 , pp. 633-647
    • Fortini, M.E.1
  • 9
    • 57149084692 scopus 로고    scopus 로고
    • Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway
    • Graziani I, Eliasz S, De Marco MA, Chen Y, Pass HI, De May RM et al. (2008). Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway. Cancer Res 68: 9678-9685.
    • (2008) Cancer Res , vol.68 , pp. 9678-9685
    • Graziani, I.1    Eliasz, S.2    De Marco, M.A.3    Chen, Y.4    Pass, H.I.5    De May, R.M.6
  • 10
    • 18144426777 scopus 로고    scopus 로고
    • Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers
    • DOI 10.1158/0008-5472.CAN-04-3132
    • Haruki N, Kawaguchi KS, Eichenberger S, Massion PP, Olson S, Gonzalez A et al. (2005). Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers. Cancer Res 65: 3555-3561. (Pubitemid 40616330)
    • (2005) Cancer Research , vol.65 , Issue.9 , pp. 3555-3561
    • Haruki, N.1    Kawaguchi, K.S.2    Eichenberger, S.3    Massion, P.P.4    Olson, S.5    Gonzalez, A.6    Carbone, D.P.7    Dang, T.P.8
  • 11
    • 33846627870 scopus 로고    scopus 로고
    • Notch expression patterns in the retina: An eye on receptor-ligand distribution during angiogenesis
    • DOI 10.1016/j.modgep.2006.11.002, PII S1567133X06001943
    • Hofmann JJ, Luisa Iruela-ArispeM. (2007). Notch expression patterns in the retina: an eye on receptor-ligand distribution during angiogenesis. Gene Expr Patterns 7: 461-470. (Pubitemid 46177950)
    • (2007) Gene Expression Patterns , vol.7 , Issue.4 , pp. 461-470
    • Hofmann, J.J.1    Luisa Iruela-Arispe, M.2
  • 12
    • 60549117358 scopus 로고    scopus 로고
    • Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy
    • Indraccolo S, Minuzzo S, Masiero M, Pusceddu I, Persano L, Moserle L et al. (2009). Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy. Cancer Res 69: 1314-1323.
    • (2009) Cancer Res , vol.69 , pp. 1314-1323
    • Indraccolo, S.1    Minuzzo, S.2    Masiero, M.3    Pusceddu, I.4    Persano, L.5    Moserle, L.6
  • 14
    • 34548572895 scopus 로고    scopus 로고
    • Gamma-Secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers
    • DOI 10.1158/0008-5472.CAN-07-1022
    • Konishi J, Kawaguchi KS, Vo H, Haruki N, Gonzalez A, Carbone DP et al. (2007). Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers. Cancer Res 67: 8051-8057. (Pubitemid 47395139)
    • (2007) Cancer Research , vol.67 , Issue.17 , pp. 8051-8057
    • Konishi, J.1    Kawaguchi, K.S.2    Vo, H.3    Haruki, N.4    Gonzalez, A.5    Carbone, D.P.6    Dang, T.P.7
  • 16
    • 34548452775 scopus 로고    scopus 로고
    • Tumor suppressor role of notch-1 signaling in neuroendocrine tumors
    • DOI 10.1634/theoncologist.12-5-535
    • Kunnimalaiyaan M, Chen H. (2007). Tumor suppressor role of Notch-1 signaling in neuroendocrine tumors. Oncologist 12: 535-542. (Pubitemid 350012116)
    • (2007) Oncologist , vol.12 , Issue.5 , pp. 535-542
    • Kunnimalaiyaan, M.1    Chen, H.2
  • 19
    • 0035753241 scopus 로고    scopus 로고
    • Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis
    • Mailhos C,Modlich U, Lewis J, Harris A, Bicknell R, Ish-Horowicz D. (2001). Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation 69: 135-144. (Pubitemid 33755062)
    • (2001) Differentiation , vol.69 , Issue.2-3 , pp. 135-144
    • Mailhos, C.1    Modlich, U.2    Lewis, J.3    Harris, A.4    Bicknell, R.5    Ish-Horowicz, D.6
  • 20
    • 67449116604 scopus 로고    scopus 로고
    • Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells
    • Meurette O, Stylianou S, Rock R, Collu GM, Gilmore AP, Brennan K. (2009). Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells. Cancer Res 69: 5015-5022.
    • (2009) Cancer Res , vol.69 , pp. 5015-5022
    • Meurette, O.1    Stylianou, S.2    Rock, R.3    Collu, G.M.4    Gilmore, A.P.5    Brennan, K.6
  • 22
    • 0035266313 scopus 로고    scopus 로고
    • Up-regulation of Bcl-2 in microvascular endothelial cells enhances intratumoral angiogenesis and accelerates tumor growth
    • Nor JE, Christensen J, Liu J, Peters M, Mooney DJ, Strieter RM et al. (2001). Up-Regulation of Bcl-2 in microvascular endothelial cells enhances intratumoral angiogenesis and accelerates tumor growth. Cancer Res 61: 2183-2188. (Pubitemid 32692045)
    • (2001) Cancer Research , vol.61 , Issue.5 , pp. 2183-2188
    • Nor, J.E.1    Christensen, J.2    Liu, J.3    Peters, M.4    Mooney, D.J.5    Strieter, R.M.6    Polverini, P.J.7
  • 24
    • 25444506836 scopus 로고    scopus 로고
    • Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
    • DOI 10.1158/0008-5472.CAN-05-1208
    • Patel NS, Li JL, Generali D, Poulsom R, Cranston DW, Harris AL. (2005). Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function. Cancer Res 65: 8690-8697. (Pubitemid 41377356)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8690-8697
    • Patel, N.S.1    Li, J.-L.2    Generali, D.3    Poulsom, R.4    Cranston, D.W.5    Harris, A.L.6
  • 25
    • 59649085554 scopus 로고    scopus 로고
    • Angiogenesis: A team effort coordinated by notch
    • Phng LK, Gerhardt H. (2009). Angiogenesis: a team effort coordinated by notch. Dev Cell 16: 196-208.
    • (2009) Dev Cell , vol.16 , pp. 196-208
    • Phng, L.K.1    Gerhardt, H.2
  • 27
    • 43049128529 scopus 로고    scopus 로고
    • Tenets of PTEN tumor suppression
    • DOI 10.1016/j.cell.2008.04.013, PII S0092867408005047
    • Salmena L, Carracedo A, Pandolfi PP. (2008). Tenets of PTEN tumor suppression. Cell 133: 403-414. (Pubitemid 351622014)
    • (2008) Cell , vol.133 , Issue.3 , pp. 403-414
    • Salmena, L.1    Carracedo, A.2    Pandolfi, P.P.3
  • 29
    • 52649116986 scopus 로고    scopus 로고
    • Dll4 activation of Notch signaling reduces tumor vascularity and inhibits tumor growth
    • Segarra M, Williams CK, Sierra Mde L, Bernardo M, McCormick PJ, Maric D et al. (2008). Dll4 activation of Notch signaling reduces tumor vascularity and inhibits tumor growth. Blood 112: 1904-1911.
    • (2008) Blood , vol.112 , pp. 1904-1911
    • Segarra, M.1    Williams, C.K.2    Sierra Mde, L.3    Bernardo, M.4    McCormick, P.J.5    Maric, D.6
  • 30
    • 77950207236 scopus 로고    scopus 로고
    • Suppression of cyclin D1 by hypoxia-inducible factor-1 via direct mechanism inhibits the proliferation and 5-fluorouracil-induced apoptosis of A549 cells
    • Wen W, Ding J, Sun W, Wu K, Ning B, Gong W et al. (2010). Suppression of cyclin D1 by hypoxia-inducible factor-1 via direct mechanism inhibits the proliferation and 5-fluorouracil-induced apoptosis of A549 cells. Cancer Res 70: 2010-2019.
    • (2010) Cancer Res , vol.70 , pp. 2010-2019
    • Wen, W.1    Ding, J.2    Sun, W.3    Wu, K.4    Ning, B.5    Gong, W.6
  • 31
    • 33846621883 scopus 로고    scopus 로고
    • CBF-1 (RBP-Jκ) binds to the PTEN promoter and regulates PTEN gene expression
    • Whelan JT, Forbes SL, Bertrand FE. (2007). CBF-1 (RBP-J kappa) binds to the PTEN promoter and regulates PTEN gene expression. Cell Cycle 6: 80-84. (Pubitemid 46173885)
    • (2007) Cell Cycle , vol.6 , Issue.1 , pp. 80-84
    • Whelan, J.T.1    Forbes, S.L.2    Bertrand, F.E.3
  • 32
    • 31544448010 scopus 로고    scopus 로고
    • Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function
    • DOI 10.1182/blood-2005-03-1000
    • Williams CK, Li JL, Murga M, Harris AL, Tosato G. (2006). Up-regulation of the Notch ligand Delta-like 4 inhibits VEGFinduced endothelial cell function. Blood 107: 931-939. (Pubitemid 43156289)
    • (2006) Blood , vol.107 , Issue.3 , pp. 931-939
    • Williams, C.K.1    Li, J.-L.2    Murga, M.3    Harris, A.L.4    Tosato, G.5
  • 33
    • 59949084951 scopus 로고    scopus 로고
    • Clinical cancer advances 2008: Major research advances in cancer treatment, prevention, and screening-a report from the American Society of Clinical Oncology
    • Winer E, Gralow J, Diller L, Karlan B, Loehrer P, Pierce L et al. (2009). Clinical cancer advances 2008: major research advances in cancer treatment, prevention, and screening-a report from the American Society of Clinical Oncology. J Clin Oncol 27: 812-826.
    • (2009) J Clin Oncol , vol.27 , pp. 812-826
    • Winer, E.1    Gralow, J.2    Diller, L.3    Karlan, B.4    Loehrer, P.5    Pierce, L.6
  • 34
    • 37549030522 scopus 로고    scopus 로고
    • Delta-like 4/Notch signaling and its therapeutic implications
    • Yan M, Plowman GD. (2007). Delta-like 4/Notch signaling and its therapeutic implications. Clin Cancer Res 13: 7243-7246.
    • (2007) Clin Cancer Res , vol.13 , pp. 7243-7246
    • Yan, M.1    Plowman, G.D.2
  • 36
    • 51849086880 scopus 로고    scopus 로고
    • PTEN: A new guardian of the genome
    • Yin Y, Shen WH. (2008). PTEN: a new guardian of the genome. Oncogene 27: 5443-5453.
    • (2008) Oncogene , vol.27 , pp. 5443-5453
    • Yin, Y.1    Shen, W.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.