메뉴 건너뛰기




Volumn 146, Issue , 2014, Pages 255-263

Regulation of cytochrome P450 mRNA expression in primary porcine hepatocytes by selected secondary plant metabolites from chicory (Cichorium intybus L.)

Author keywords

Bioactive compounds; Boar taint; Cryopreservation; Detoxification; Gene regulation; Liver metabolism; Primary hepatocytes

Indexed keywords

BIOACTIVE COMPOUNDS; BOAR TAINT; CRYO-PRESERVATION; LIVER METABOLISMS; PRIMARY HEPATOCYTES;

EID: 84884965888     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2013.09.068     Document Type: Article
Times cited : (33)

References (39)
  • 1
    • 80054723955 scopus 로고    scopus 로고
    • Cytochrome P450 pig liver pie: Determination of individual cytochrome P450 isoform contents in microsomes from two pig livers using liquid chromatography in conjunction with mass spectrometry
    • B. Achour, J. Barber, and A. Rostami-Hodjegan Cytochrome P450 pig liver pie: Determination of individual cytochrome P450 isoform contents in microsomes from two pig livers using liquid chromatography in conjunction with mass spectrometry Drug Metabolism and Disposition 39 11 2011 2130 2134
    • (2011) Drug Metabolism and Disposition , vol.39 , Issue.11 , pp. 2130-2134
    • Achour, B.1    Barber, J.2    Rostami-Hodjegan, A.3
  • 2
    • 0037676080 scopus 로고    scopus 로고
    • Antihepatotoxic activity of seeds of Cichorium intybus
    • DOI 10.1016/S0378-8741(03)00145-4
    • B. Ahmed, T.A. Al-Howiriny, and A.B. Siddiqui Antihepatotoxic activity of seeds of Cichorium intybus Journal of Ethnopharmacology 87 2-3 2003 237 240 (Pubitemid 36809158)
    • (2003) Journal of Ethnopharmacology , vol.87 , Issue.2-3 , pp. 237-240
    • Ahmed, B.1    Al-Howiriny, T.A.2    Siddiqui, A.B.3
  • 3
    • 0035068138 scopus 로고    scopus 로고
    • Cichorium intybus L - Cultivation, processing, utility, value addition and biotechnology, with an emphasis on current status and future prospects
    • DOI 10.1002/jsfa.817
    • H.P. Bais, and G.A. Ravishankar Cichorium intybus L. - Cultivation, processing, utility, value addition and biotechnology, with an emphasis on current status and future prospects Journal of the Science of Food and Agriculture 81 5 2001 467 484 (Pubitemid 32285729)
    • (2001) Journal of the Science of Food and Agriculture , vol.81 , Issue.5 , pp. 467-484
    • Bais, H.P.1    Ravishankar, G.A.2
  • 4
    • 21744451835 scopus 로고    scopus 로고
    • Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor
    • DOI 10.1124/mol.104.009019
    • O. Burk, K.A. Arnold, A.K. Nussler, E. Schaeffeler, E. Efimova, and B.A. Avery Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor Molecular Pharmacology 67 6 2005 1954 1965 (Pubitemid 41007777)
    • (2005) Molecular Pharmacology , vol.67 , Issue.6 , pp. 1954-1965
    • Burk, O.1    Arnold, K.A.2    Nussler, A.K.3    Schaeffeler, E.4    Efimova, E.5    Avery, B.A.6    Avery, M.A.7    Fromm, M.F.8    Eichelbaum, M.9
  • 5
    • 40849087860 scopus 로고    scopus 로고
    • A sensory description of boar taint and the effects of crude and dried chicory roots (Cichorium intybus L.) and inulin feeding in male and female pork
    • DOI 10.1016/j.meatsci.2007.09.009, PII S0309174007003002
    • D.V. Byrne, S.M. Thamsborg, and L.L. Hansen A sensory description of boar taint and the effects of crude and dried chicory roots (Cichorium intybus L.) and inulin feeding in male and female pork Meat Science 79 2 2008 252 269 (Pubitemid 351400523)
    • (2008) Meat Science , vol.79 , Issue.2 , pp. 252-269
    • Byrne, D.V.1    Thamsborg, S.M.2    Hansen, L.L.3
  • 7
    • 73349087148 scopus 로고    scopus 로고
    • Activation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) by herbal medicines
    • T. Chang Activation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) by herbal medicines The AAPS Journal 11 3 2009 590 601
    • (2009) The AAPS Journal , vol.11 , Issue.3 , pp. 590-601
    • Chang, T.1
  • 8
    • 33646693667 scopus 로고    scopus 로고
    • Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR)
    • DOI 10.1080/03602530600569828, PII T22707844
    • T.K.H. Chang, and D.J. Waxman Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) Drug Metabolism Reviews 38 1-2 2006 51 73 (Pubitemid 43738999)
    • (2006) Drug Metabolism Reviews , vol.38 , Issue.1-2 , pp. 51-73
    • Chang, T.K.H.1    Waxman, D.J.2
  • 9
    • 0037140383 scopus 로고    scopus 로고
    • Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes
    • DOI 10.1016/S0009-2797(02)00015-7, PII S0009279702000157
    • E. Doran, F.W. Whittington, J.D. Wood, and J.D. McGivan Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes Chemico-Biological Interactions 140 1 2002 81 92 (Pubitemid 34614526)
    • (2002) Chemico-Biological Interactions , vol.140 , Issue.1 , pp. 81-92
    • Doran, E.1    Whittington, F.W.2    Wood, J.D.3    McGivan, J.D.4
  • 10
    • 33646256118 scopus 로고    scopus 로고
    • Regulation of gender-dependent CYP2A expression in pigs: Involvement of androgens and CAR
    • M. Gillberg, M.T. Skaanild, and C. Friis Regulation of gender-dependent CYP2A expression in pigs: Involvement of androgens and CAR Basic & Clinical Pharmacology & Toxicology 98 5 2006 480 487
    • (2006) Basic & Clinical Pharmacology & Toxicology , vol.98 , Issue.5 , pp. 480-487
    • Gillberg, M.1    Skaanild, M.T.2    Friis, C.3
  • 11
    • 38949094492 scopus 로고    scopus 로고
    • Cytochrome P450 and chemical toxicology
    • DOI 10.1021/tx700079z
    • F.P. Guengerich Cytochrome P450 and chemical toxicology Chemical Research in Toxicology 21 1 2007 70 83 (Pubitemid 351219709)
    • (2008) Chemical Research in Toxicology , vol.21 , Issue.1 , pp. 70-83
    • Guengerich, F.P.1
  • 12
    • 67651208865 scopus 로고    scopus 로고
    • Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes
    • B.H. Hellum, Z. Hu, and O.G. Nilsen Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes Basic & Clinical Pharmacology & Toxicology 105 1 2009 58 63
    • (2009) Basic & Clinical Pharmacology & Toxicology , vol.105 , Issue.1 , pp. 58-63
    • Hellum, B.H.1    Hu, Z.2    Nilsen, O.G.3
  • 13
    • 1542781600 scopus 로고    scopus 로고
    • A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR
    • DOI 10.1172/JCI200418385
    • W. Huang, J. Zhang, and D.D. Moore A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR Journal of Clinical Investigation 113 1 2004 137 143 (Pubitemid 38541640)
    • (2004) Journal of Clinical Investigation , vol.113 , Issue.1 , pp. 137-143
    • Huang, W.1    Zhang, J.2    Moore, D.D.3
  • 14
    • 0036218023 scopus 로고    scopus 로고
    • Examination of cytochrome P450 content of primary porcine hepatocyte cultures with various media formulations for use in bioartificial liver devices
    • S.A. Keatch, L.J. Nelson, J.I. Mason, P.C. Hayes, and J.N. Plevris Examination of cytochrome P450 content of primary porcine hepatocyte cultures with various media formulations for use in bioartificial liver devices Journal of Artificial Organs 5 1 2002 37 43 (Pubitemid 34285864)
    • (2002) Journal of Artificial Organs , vol.5 , Issue.1 , pp. 37-43
    • Keatch, S.A.1    Nelson, L.J.2    Mason, J.I.3    Hayes, P.C.4    Plevris, J.N.5
  • 16
    • 0022511846 scopus 로고
    • Use of a low-speed, iso-density percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations
    • B. Kreamer, J. Staecker, N. Sawada, G. Sattler, M. Hsia, and H. Pitot Use of a low-speed, iso-density percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations In Vitro Cellular & Developmental Biology - Plant 22 4 1986 201 211 (Pubitemid 16075195)
    • (1986) Vitro , vol.22 , Issue.4 , pp. 201-211
    • Kreamer, B.L.1    Staecker, J.L.2    Sawada, N.3
  • 17
    • 1542686227 scopus 로고    scopus 로고
    • Modulation of AhR-mediated CYP1A1 mRNA and EROD activities by 17β-estradiol and dexamethasone in TCDD-induced H411E cells
    • DOI 10.1093/toxsci/kfh045
    • K.P. Lai, M.H. Wong, and C.K.C. Wong Modulation of AhR-mediated CYP1A1 mRNA and EROD activities by 17β-estradiol and dexamethasone in TCDD-induced H411E cells Toxicological Sciences 78 1 2004 41 49 (Pubitemid 38351422)
    • (2004) Toxicological Sciences , vol.78 , Issue.1 , pp. 41-49
    • Lai, K.P.1    Wong, M.H.2    Wong, C.K.C.3
  • 18
    • 20644437301 scopus 로고    scopus 로고
    • Phase I and II metabolism and carbohydrate metabolism in cultured cryopreserved porcine hepatocytes
    • DOI 10.1016/j.cbi.2005.03.040, PII S0009279705001110
    • A.D.B. Loven, A.K. Olsen, C. Friis, and B. Andersen Phase I and II metabolism and carbohydrate metabolism in cultured cryopreserved porcine hepatocytes Chemico-Biological Interactions 155 1-2 2005 21 30 (Pubitemid 40835987)
    • (2005) Chemico-Biological Interactions , vol.155 , Issue.1-2 , pp. 21-30
    • Loven, A.-D.B.1    Olsen, A.K.2    Friis, C.3    Andersen, B.4
  • 19
    • 77349086874 scopus 로고    scopus 로고
    • Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system
    • J. Matal, Z. Matuskova, A. Tunkova, E. Anzenbacherova, and P. Anzenbacher Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system Neuroendocrinology Letters 30 2009 36 40
    • (2009) Neuroendocrinology Letters , vol.30 , pp. 36-40
    • Matal, J.1    Matuskova, Z.2    Tunkova, A.3    Anzenbacherova, E.4    Anzenbacher, P.5
  • 20
    • 67349113389 scopus 로고    scopus 로고
    • Expression and inducibility of CYP1A1, 1A2, 1B1 by β-naphthoflavone and CYP2B22, 3A22, 3A29, 3A46 by rifampicin in the respiratory and olfactory mucosa of pig
    • A. Messina, A. Nannelli, R. Fiorio, V. Longo, and P.G. Gervasi Expression and inducibility of CYP1A1, 1A2, 1B1 by β-naphthoflavone and CYP2B22, 3A22, 3A29, 3A46 by rifampicin in the respiratory and olfactory mucosa of pig Toxicology 260 1-3 2009 47 52
    • (2009) Toxicology , vol.260 , Issue.13 , pp. 47-52
    • Messina, A.1    Nannelli, A.2    Fiorio, R.3    Longo, V.4    Gervasi, P.G.5
  • 21
    • 0031732210 scopus 로고    scopus 로고
    • Characterization of cytochrome P450 isoenzymes in primary cultures of pig hepatocytes
    • DOI 10.1016/S0887-2333(98)00053-8, PII S0887233398000538
    • M. Monshouwer, G.A.E. van't Klooster, S.M. Nijmeijer, R.F. Witkamp, and A.S.J.P. van Miert Characterization of cytochrome P450 isoenzymes in primary cultures of pig hepatocytes Toxicology in Vitro 12 6 1998 715 723 (Pubitemid 28555843)
    • (1998) Toxicology in Vitro , vol.12 , Issue.6 , pp. 715-723
    • Monshouwer, M.1    Van'T Klooster, G.A.E.2    Nijmeijer, S.M.3    Witkamp, R.F.4    Van Miert, A.S.J.P.5
  • 22
    • 0029962068 scopus 로고    scopus 로고
    • Suppression of cytochrome P450- and UDP glucuronosyl transferase- dependent enzyme activities by proinflammatory cytokines and possible role of nitric oxide in primary cultures of pig hepatocytes
    • DOI 10.1006/taap.1996.0077
    • M. Monshouwer, R.F. Witkamp, S.M. Nijmeijer, J.G. Van Amsterdam, and A.S.J.P. Van Miert Suppression of cytochrome P450- and UDP glucuronosyl transferase-dependent enzyme activities by proinflammatory cytokines and possible role of nitric oxide in primary cultures of pig hepatocytes Toxicology and Applied Pharmacology 137 2 1996 237 244 (Pubitemid 26130141)
    • (1996) Toxicology and Applied Pharmacology , vol.137 , Issue.2 , pp. 237-244
    • Monshouwer, M.1    Witkamp, R.F.2    Nijmeijer, S.M.3    Van Amsterdam, J.G.4    Van Miert, A.S.J.P.A.M.5
  • 23
    • 71749085239 scopus 로고    scopus 로고
    • Effect of β-naphthoflavone on AhR-regulated genes (CYP1A1, 1A2, 1B1, 2S1, Nrf2, and GST) and antioxidant enzymes in various brain regions of pig
    • A. Nannelli, F. Rossignolo, R. Tolando, P. Rossato, V. Longo, and P.G. Gervasi Effect of β-naphthoflavone on AhR-regulated genes (CYP1A1, 1A2, 1B1, 2S1, Nrf2, and GST) and antioxidant enzymes in various brain regions of pig Toxicology 265 3 2009 69 79
    • (2009) Toxicology , vol.265 , Issue.3 , pp. 69-79
    • Nannelli, A.1    Rossignolo, F.2    Tolando, R.3    Rossato, P.4    Longo, V.5    Gervasi, P.G.6
  • 24
    • 77949659019 scopus 로고    scopus 로고
    • Expression and distribution of CYP3A genes, CYP2B22, and MDR1, MRP1, MRP2, LRP efflux transporters in brain of control and rifampicin-treated pigs
    • A. Nannelli, F. Rossignolo, R. Tolando, P. Rossato, M. Pellegatti, and V. Longo Expression and distribution of CYP3A genes, CYP2B22, and MDR1, MRP1, MRP2, LRP efflux transporters in brain of control and rifampicin-treated pigs Molecular and Cellular Biochemistry 337 1 2010 133 143
    • (2010) Molecular and Cellular Biochemistry , vol.337 , Issue.1 , pp. 133-143
    • Nannelli, A.1    Rossignolo, F.2    Tolando, R.3    Rossato, P.4    Pellegatti, M.5    Longo, V.6
  • 26
    • 0033664347 scopus 로고    scopus 로고
    • Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: Consequences on cytochrome P450 gene regulation
    • J.M. Pascussi, S. Gerbal-Chaloin, J.M. Fabre, P. Maurel, and M.J. Vilarem Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: Consequences on cytochrome P450 gene regulation Molecular Pharmacology 58 6 2000 1441 1450
    • (2000) Molecular Pharmacology , vol.58 , Issue.6 , pp. 1441-1450
    • Pascussi, J.M.1    Gerbal-Chaloin, S.2    Fabre, J.M.3    Maurel, P.4    Vilarem, M.J.5
  • 27
    • 84859261844 scopus 로고    scopus 로고
    • Feeding dried chicory root to pigs decrease androstenone accumulation in fat by increasing hepatic 3β hydroxysteroid dehydrogenase expression
    • M.K. Rasmussen, C. Brunius, G. Zamaratskaia, and B. Ekstrand Feeding dried chicory root to pigs decrease androstenone accumulation in fat by increasing hepatic 3β hydroxysteroid dehydrogenase expression The Journal of Steroid Biochemistry and Molecular Biology 130 2012 90 95
    • (2012) The Journal of Steroid Biochemistry and Molecular Biology , vol.130 , pp. 90-95
    • Rasmussen, M.K.1    Brunius, C.2    Zamaratskaia, G.3    Ekstrand, B.4
  • 28
    • 84866303627 scopus 로고    scopus 로고
    • Dried chicory root modifies the activity and expression of porcine hepatic CYP3A but not 2C - Effect of in vitro and in vivo exposure
    • M.K. Rasmussen, G. Zamaratskaia, B. Andersen, and B. Ekstrand Dried chicory root modifies the activity and expression of porcine hepatic CYP3A but not 2C - Effect of in vitro and in vivo exposure Food and Chemical Toxicology 50 11 2012 4175 4179
    • (2012) Food and Chemical Toxicology , vol.50 , Issue.11 , pp. 4175-4179
    • Rasmussen, M.K.1    Zamaratskaia, G.2    Andersen, B.3    Ekstrand, B.4
  • 29
    • 78650175627 scopus 로고    scopus 로고
    • In vivo effect of dried chicory root (Cichorium intybus L.) on xenobiotica metabolising cytochrome P450 enzymes in porcine liver
    • M.K. Rasmussen, G. Zamaratskaia, and B. Ekstrand In vivo effect of dried chicory root (Cichorium intybus L.) on xenobiotica metabolising cytochrome P450 enzymes in porcine liver Toxicology Letters 200 1-2 2011 88 91
    • (2011) Toxicology Letters , vol.200 , Issue.12 , pp. 88-91
    • Rasmussen, M.K.1    Zamaratskaia, G.2    Ekstrand, B.3
  • 30
    • 79959419405 scopus 로고    scopus 로고
    • Gender-related differences in cytochrome P450 in porcine liver - Implication for activity, expression and inhibition by testicular steroids
    • M.K. Rasmussen, G. Zamaratskaia, and B. Ekstrand Gender-related differences in cytochrome P450 in porcine liver - Implication for activity, expression and inhibition by testicular steroids Reproduction in Domestic Animals 46 4 2011 616 623
    • (2011) Reproduction in Domestic Animals , vol.46 , Issue.4 , pp. 616-623
    • Rasmussen, M.K.1    Zamaratskaia, G.2    Ekstrand, B.3
  • 31
    • 0015409143 scopus 로고
    • Preparation of rat liver cells: I. Effect of Ca2+ on enzymatic dispersion of isolated, perfused liver
    • P.O. Seglen Preparation of rat liver cells: I. Effect of Ca2+ on enzymatic dispersion of isolated, perfused liver Experimental Cell Research 74 2 1972 450 454
    • (1972) Experimental Cell Research , vol.74 , Issue.2 , pp. 450-454
    • Seglen, P.O.1
  • 33
    • 0033790825 scopus 로고    scopus 로고
    • Expression changes of CYP2A and CYP3A in microsomes from pig liver and cultured hepatocytes
    • M.T. Skaanild, and C. Friis Expression changes of CYP2A and CYP3A in microsomes from pig liver and cultured hepatocytes Pharmacology & Toxicology 87 4 2000 174 178
    • (2000) Pharmacology & Toxicology , vol.87 , Issue.4 , pp. 174-178
    • Skaanild, M.T.1    Friis, C.2
  • 35
    • 33645810602 scopus 로고    scopus 로고
    • The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes
    • M.A. Terner, W.J. Gilmore, Y.P. Lou, and E.J. Squires The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes Drug Metabolism and Disposition 34 5 2006 848 854
    • (2006) Drug Metabolism and Disposition , vol.34 , Issue.5 , pp. 848-854
    • Terner, M.A.1    Gilmore, W.J.2    Lou, Y.P.3    Squires, E.J.4
  • 37
    • 84859322283 scopus 로고    scopus 로고
    • The roles of different porcine cytochrome P450 enzymes and cytochrome b5A in skatole metabolism
    • P. Wiercinska, Y. Lou, and E.J. Squires The roles of different porcine cytochrome P450 enzymes and cytochrome b5A in skatole metabolism Animal 6 Special Issue 05 2012 834 845
    • (2012) Animal , vol.6 , Issue.SPEC ISSUE 05 , pp. 834-845
    • Wiercinska, P.1    Lou, Y.2    Squires, E.J.3
  • 38
    • 80054051468 scopus 로고    scopus 로고
    • Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitor
    • D. Yang, J. Yang, D. Shi, R. Deng, and B. Yan Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitor British Journal of Pharmacology 164 5 2011 1547 1557
    • (2011) British Journal of Pharmacology , vol.164 , Issue.5 , pp. 1547-1557
    • Yang, D.1    Yang, J.2    Shi, D.3    Deng, R.4    Yan, B.5
  • 39
    • 0031544183 scopus 로고    scopus 로고
    • Isolation and primary culture of adult pig hepatocytes
    • X.D. Zhou, T. Tokiwa, J. Kano, and M. Kodama Isolation and primary culture of adult pig hepatocytes Methods in Cell Science 19 4 1998 277 284
    • (1998) Methods in Cell Science , vol.19 , Issue.4 , pp. 277-284
    • Zhou, X.D.1    Tokiwa, T.2    Kano, J.3    Kodama, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.