-
1
-
-
0029680494
-
Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver
-
Amato G., Longo V., Mazzaccaro A., and Gervasi P.G. Microsomal oxidation of N,N-diethylformamide and its effect on P450-dependent monooxygenases in rat liver. Chem. Res. Toxicol. 9 (1996) 882-890
-
(1996)
Chem. Res. Toxicol.
, vol.9
, pp. 882-890
-
-
Amato, G.1
Longo, V.2
Mazzaccaro, A.3
Gervasi, P.G.4
-
2
-
-
0025032790
-
Localization, distribution and induction of xenobiotic metabolising enzymes and aryl hydrocarbon hydroxylase activity within lung
-
Baron J., and Voigt J.M. Localization, distribution and induction of xenobiotic metabolising enzymes and aryl hydrocarbon hydroxylase activity within lung. Pharmacol. Ther. 47 (1990) 419-445
-
(1990)
Pharmacol. Ther.
, vol.47
, pp. 419-445
-
-
Baron, J.1
Voigt, J.M.2
-
3
-
-
34548849104
-
Inducibility of AhR-regulated CYP genes by β-naphthoflavone in the liver, lung, kidney and heart of the pig
-
Chirulli V., Marvasi L., Zaghini A., Fiorio R., Longo V., and Gervasi P.G. Inducibility of AhR-regulated CYP genes by β-naphthoflavone in the liver, lung, kidney and heart of the pig. Toxicology 240 (2007) 25-37
-
(2007)
Toxicology
, vol.240
, pp. 25-37
-
-
Chirulli, V.1
Marvasi, L.2
Zaghini, A.3
Fiorio, R.4
Longo, V.5
Gervasi, P.G.6
-
5
-
-
1242307956
-
Gene expression profiling in respiratory tissues from rats exposed to mainstream cigarette smoke
-
Gebel S., Gerstmayer B., Bosio A., Haussmann H.-J., Miert E.V., and Muller T. Gene expression profiling in respiratory tissues from rats exposed to mainstream cigarette smoke. Carcinogenesis 25 (2004) 169-178
-
(2004)
Carcinogenesis
, vol.25
, pp. 169-178
-
-
Gebel, S.1
Gerstmayer, B.2
Bosio, A.3
Haussmann, H.-J.4
Miert, E.V.5
Muller, T.6
-
6
-
-
0036019495
-
Induction of olfactory mucosa and liver metabolism of lidocaine by 2,3,7,8-tetrachorodibenzo-p-dioxin
-
Genter M.B., Apparaju S., and Desai P.B. Induction of olfactory mucosa and liver metabolism of lidocaine by 2,3,7,8-tetrachorodibenzo-p-dioxin. J. Biochem. Mol. Toxicol. 16 (2002) 128-133
-
(2002)
J. Biochem. Mol. Toxicol.
, vol.16
, pp. 128-133
-
-
Genter, M.B.1
Apparaju, S.2
Desai, P.B.3
-
7
-
-
0023204475
-
Uptake and specific binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the olfactory mucosa of mice and rats
-
Gillner M., Brittebo E.B., Brant I., Soderkvist P., Appelgren L.-E., and Gustafsson J.-A. Uptake and specific binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the olfactory mucosa of mice and rats. Cancer Res. 47 (1987) 4150-4159
-
(1987)
Cancer Res.
, vol.47
, pp. 4150-4159
-
-
Gillner, M.1
Brittebo, E.B.2
Brant, I.3
Soderkvist, P.4
Appelgren, L.-E.5
Gustafsson, J.-A.6
-
8
-
-
33745656989
-
Regulating the regulator: factors that controls levels and activity of the aryl hydrocarbon receptor
-
Harper P.A., Riddick D.S., and Okey A.B. Regulating the regulator: factors that controls levels and activity of the aryl hydrocarbon receptor. Biochem. Pharmacol. 72 (2006) 267-279
-
(2006)
Biochem. Pharmacol.
, vol.72
, pp. 267-279
-
-
Harper, P.A.1
Riddick, D.S.2
Okey, A.B.3
-
9
-
-
0023216022
-
Monoclonal antibodies to ethanol-induced rat liver cytochrome P-450 that metabolizes aniline and nitrosamines
-
Ko I.Y., Park S.S., Song B.J., Patten C., Tan Y., Ha Y.C., Yang C.S., and Gelboin H.V. Monoclonal antibodies to ethanol-induced rat liver cytochrome P-450 that metabolizes aniline and nitrosamines. Cancer Res. 47 (1987) 3101-3109
-
(1987)
Cancer Res.
, vol.47
, pp. 3101-3109
-
-
Ko, I.Y.1
Park, S.S.2
Song, B.J.3
Patten, C.4
Tan, Y.5
Ha, Y.C.6
Yang, C.S.7
Gelboin, H.V.8
-
10
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
11
-
-
0030184740
-
Bioactivation of aflatoxin B1 in the nasal and tracheal mucosa in swine
-
Larsson P., and Tjalve H. Bioactivation of aflatoxin B1 in the nasal and tracheal mucosa in swine. J. Anim. Sci. 74 (1996) 1672-1680
-
(1996)
J. Anim. Sci.
, vol.74
, pp. 1672-1680
-
-
Larsson, P.1
Tjalve, H.2
-
12
-
-
2342512149
-
Regulation of cytochrome P450 gene expression in the olfactory mucosa
-
Ling G., Gu J., Genter M.B., Zhuo X., and Ding X. Regulation of cytochrome P450 gene expression in the olfactory mucosa. Chem.-Biol. Interact. 147 (2004) 247-258
-
(2004)
Chem.-Biol. Interact.
, vol.147
, pp. 247-258
-
-
Ling, G.1
Gu, J.2
Genter, M.B.3
Zhuo, X.4
Ding, X.5
-
13
-
-
0027365068
-
Acetone-dependent regulation of cytochrome P4502E1 and P4502B1 in rat nasal mucosa
-
Longo V., and Ingelman-Sundberg M. Acetone-dependent regulation of cytochrome P4502E1 and P4502B1 in rat nasal mucosa. Biochem. Pharmacol. 46 (1993) 1945-1951
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 1945-1951
-
-
Longo, V.1
Ingelman-Sundberg, M.2
-
14
-
-
0034213086
-
Effect of starvation and chlomethiazole on cytochrome P450s of rat nasal mucosa
-
Longo V., Ingelman-Sundberg M., Amato G., Salvetti A., and Gervasi P.G. Effect of starvation and chlomethiazole on cytochrome P450s of rat nasal mucosa. Biochem. Pharmacol. 59 (2000) 1425-1432
-
(2000)
Biochem. Pharmacol.
, vol.59
, pp. 1425-1432
-
-
Longo, V.1
Ingelman-Sundberg, M.2
Amato, G.3
Salvetti, A.4
Gervasi, P.G.5
-
15
-
-
0026176952
-
Drug metabolizing enzymes in liver, olfactory and respiratory epithelium of cattle
-
Longo V., Mazzaccaro A., Naldi F., and Gervasi P.G. Drug metabolizing enzymes in liver, olfactory and respiratory epithelium of cattle. J. Biochem. Toxicol. 6 (1991) 123-128
-
(1991)
J. Biochem. Toxicol.
, vol.6
, pp. 123-128
-
-
Longo, V.1
Mazzaccaro, A.2
Naldi, F.3
Gervasi, P.G.4
-
17
-
-
0022350885
-
Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat
-
Lubet R.A., Mayer R.T., Cameron J.W., Nims R.W., Burke M.D., Wolf T., and Guengerich F.P. Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat. Arch. Biochem. Biophys. 238 (1985) 43-48
-
(1985)
Arch. Biochem. Biophys.
, vol.238
, pp. 43-48
-
-
Lubet, R.A.1
Mayer, R.T.2
Cameron, J.W.3
Nims, R.W.4
Burke, M.D.5
Wolf, T.6
Guengerich, F.P.7
-
18
-
-
0031720849
-
Xenobiotic metabolizing enzymes in pig nasal and hepatic tissues
-
Marini S., Longo V., Mazzaccaro A., and Gervasi P.G. Xenobiotic metabolizing enzymes in pig nasal and hepatic tissues. Xenobiotica 10 (1998) 923-935
-
(1998)
Xenobiotica
, vol.10
, pp. 923-935
-
-
Marini, S.1
Longo, V.2
Mazzaccaro, A.3
Gervasi, P.G.4
-
19
-
-
56749170689
-
Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2
-
Messina A., Chirulli V., Gervasi P.G., and Longo V. Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2. Xenobiotica 38 (2008) 1453-1470
-
(2008)
Xenobiotica
, vol.38
, pp. 1453-1470
-
-
Messina, A.1
Chirulli, V.2
Gervasi, P.G.3
Longo, V.4
-
20
-
-
0035984813
-
Drug transport into the mammalian brain: the nasal pathway and its specific metabolic barrier
-
Minn A., Leclerc S., Heydel J.M., Minn A.L., Denizot C., Cattarelli M., Netter P., and Gradinaru D. Drug transport into the mammalian brain: the nasal pathway and its specific metabolic barrier. J. Drug Target. 10 (2002) 285-296
-
(2002)
J. Drug Target.
, vol.10
, pp. 285-296
-
-
Minn, A.1
Leclerc, S.2
Heydel, J.M.3
Minn, A.L.4
Denizot, C.5
Cattarelli, M.6
Netter, P.7
Gradinaru, D.8
-
21
-
-
22944447754
-
Characterization of microsomal cytochrome P450 dependent monooxygenases in the rat olfactory mucosa
-
Minn A., Pelczar H., Denizot C., Martinet M., Heydel J.M., Walther B., Minn A.L., Goudonnet H., and Artur Y. Characterization of microsomal cytochrome P450 dependent monooxygenases in the rat olfactory mucosa. Drug Metab. Dispos. 33 (2005) 1229-1237
-
(2005)
Drug Metab. Dispos.
, vol.33
, pp. 1229-1237
-
-
Minn, A.1
Pelczar, H.2
Denizot, C.3
Martinet, M.4
Heydel, J.M.5
Walther, B.6
Minn, A.L.7
Goudonnet, H.8
Artur, Y.9
-
22
-
-
0036256351
-
Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoato x receptor (BXR) define three pharmacologically distinct cases of nuclear receptors
-
Moore L.B., Maglich J.M., McKee D.D., Wisely B., Willson T.M., Kliewer S.A., Lambert M.H., and Moore J.T. Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoato x receptor (BXR) define three pharmacologically distinct cases of nuclear receptors. Mol. Endocrinol. 16 (2002) 977-986
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 977-986
-
-
Moore, L.B.1
Maglich, J.M.2
McKee, D.D.3
Wisely, B.4
Willson, T.M.5
Kliewer, S.A.6
Lambert, M.H.7
Moore, J.T.8
-
23
-
-
53349165544
-
Expression and induction by rifampicin of CAR- and PXR-regulated CYP2B and CYP3A in liver, kidney and airways of pig
-
Nannelli A., Chirulli V., Longo V., and Gervasi P.G. Expression and induction by rifampicin of CAR- and PXR-regulated CYP2B and CYP3A in liver, kidney and airways of pig. Toxicology 252 (2008) 105-112
-
(2008)
Toxicology
, vol.252
, pp. 105-112
-
-
Nannelli, A.1
Chirulli, V.2
Longo, V.3
Gervasi, P.G.4
-
24
-
-
0033990325
-
Role of the aromatic hydrocarbon receptor and [Ah]gene battery in the oxidative stress response, cell cycle control and apoptosis
-
Nebert D.W., Roe A.L., Dieter M.Z., Solis W.A., Yang Y., and Dalton T.P. Role of the aromatic hydrocarbon receptor and [Ah]gene battery in the oxidative stress response, cell cycle control and apoptosis. Biochem. Pharmacol. 59 (2000) 65-85
-
(2000)
Biochem. Pharmacol.
, vol.59
, pp. 65-85
-
-
Nebert, D.W.1
Roe, A.L.2
Dieter, M.Z.3
Solis, W.A.4
Yang, Y.5
Dalton, T.P.6
-
25
-
-
0029588524
-
The role of P450 enzymes in hepatic and extrahepatic human drug toxicity
-
385-324
-
Park B.K., Pirmohamed M., and Kitteringham N.R. The role of P450 enzymes in hepatic and extrahepatic human drug toxicity. Pharmacol. Ther. 68 (1995) 385-324
-
(1995)
Pharmacol. Ther.
, vol.68
-
-
Park, B.K.1
Pirmohamed, M.2
Kitteringham, N.R.3
-
26
-
-
0036317196
-
Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice
-
Shimada T., Inoue K., Suzuki Y., Kawai T., Azuma E., Nakajima T., Shindo M., Kurose K., Sugie Yamagishi A., Fujii Kuriyama Y., and Hashimoto M. Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice. Carcinogenesis 23 (2002) 1199-1207
-
(2002)
Carcinogenesis
, vol.23
, pp. 1199-1207
-
-
Shimada, T.1
Inoue, K.2
Suzuki, Y.3
Kawai, T.4
Azuma, E.5
Nakajima, T.6
Shindo, M.7
Kurose, K.8
Sugie Yamagishi, A.9
Fujii Kuriyama, Y.10
Hashimoto, M.11
-
27
-
-
33745002984
-
Porcine cytochrome P450 and metabolism
-
Skaanild M.T. Porcine cytochrome P450 and metabolism. Curr. Pharm. Des. 12 (2006) 1421-1427
-
(2006)
Curr. Pharm. Des.
, vol.12
, pp. 1421-1427
-
-
Skaanild, M.T.1
-
28
-
-
0033664783
-
Substrate-dependent modulation of CYP3A catalytic activity: analysis of 27 test compounds with four fluorimetric substrates
-
Stresser D.M., Blanchard A.P., Turner S.D., Erve J.C.L., Dandeneau A.A., Miller V.P., and Crespi L.C. Substrate-dependent modulation of CYP3A catalytic activity: analysis of 27 test compounds with four fluorimetric substrates. Drug Metab. Dispos. 28 (2000) 1440-1448
-
(2000)
Drug Metab. Dispos.
, vol.28
, pp. 1440-1448
-
-
Stresser, D.M.1
Blanchard, A.P.2
Turner, S.D.3
Erve, J.C.L.4
Dandeneau, A.A.5
Miller, V.P.6
Crespi, L.C.7
-
29
-
-
2342493476
-
Regulation of the cytochrome P4502A genes
-
Su T., and Ding X. Regulation of the cytochrome P4502A genes. Toxicol. Appl. Pharmacol. 199 (2004) 285-294
-
(2004)
Toxicol. Appl. Pharmacol.
, vol.199
, pp. 285-294
-
-
Su, T.1
Ding, X.2
-
31
-
-
0030679602
-
Metabolic capacity of nasal tissue: interspecies comparisons of xenobiotic-metabolising enzymes
-
Thornton-Manning J.R., and Dahl A.R. Metabolic capacity of nasal tissue: interspecies comparisons of xenobiotic-metabolising enzymes. Mutat. Res. 380 (1997) 43-59
-
(1997)
Mutat. Res.
, vol.380
, pp. 43-59
-
-
Thornton-Manning, J.R.1
Dahl, A.R.2
-
32
-
-
0037327003
-
The orphan nuclear receptor HNF4α determines PXR-and CAR-mediated xenobiotic induction of CYP3A4
-
Tirona R.G., Lee W., Leake B.F., Lan L.-B., Cline C.B., Lamba V., Parviz F., Ducan S.A., Inoue Y., Gonzalez F.J., Schuetz E., and Kim R.B. The orphan nuclear receptor HNF4α determines PXR-and CAR-mediated xenobiotic induction of CYP3A4. Nat. Med. 9 (2003) 220-224
-
(2003)
Nat. Med.
, vol.9
, pp. 220-224
-
-
Tirona, R.G.1
Lee, W.2
Leake, B.F.3
Lan, L.-B.4
Cline, C.B.5
Lamba, V.6
Parviz, F.7
Ducan, S.A.8
Inoue, Y.9
Gonzalez, F.J.10
Schuetz, E.11
Kim, R.B.12
-
33
-
-
0009482260
-
Electrophoretic transfer of proteins from polyacrylamide gel to nitrocellulose sheets: procedure and some applications
-
Towbin H.T., Staehelin P., and Gordon J. Electrophoretic transfer of proteins from polyacrylamide gel to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. U.S.A. 76 (1979) 4350-4354
-
(1979)
Proc. Natl. Acad. Sci. U.S.A.
, vol.76
, pp. 4350-4354
-
-
Towbin, H.T.1
Staehelin, P.2
Gordon, J.3
-
34
-
-
0027139782
-
Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal and purified CYP1A1 and CYP1A2
-
Tsyrlov I.B., Goldfarb I.S., and Gelboin H.V. Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal and purified CYP1A1 and CYP1A2. Arch. Biochem. Biophys. 307 (1993) 259-266
-
(1993)
Arch. Biochem. Biophys.
, vol.307
, pp. 259-266
-
-
Tsyrlov, I.B.1
Goldfarb, I.S.2
Gelboin, H.V.3
-
35
-
-
0028986147
-
Oxidation of aflatoxin B1 by bacteria recombinant human cytochrome P450 enzymes
-
Ueng V.-F.T., Shimada H., Yamazaky, and Guengerich F.P. Oxidation of aflatoxin B1 by bacteria recombinant human cytochrome P450 enzymes. Chem. Res. Toxicol. 8 (1995) 218-225
-
(1995)
Chem. Res. Toxicol.
, vol.8
, pp. 218-225
-
-
Ueng, V.-F.T.1
Shimada, H.2
Yamazaky3
Guengerich, F.P.4
-
36
-
-
0027240932
-
Localization and induction of cytochrome P4501A1 and aryl hydrocarbon hydroxylase activity in rat nasal mucosa
-
Voigt J.M., Guengerich F.P., and Baron J. Localization and induction of cytochrome P4501A1 and aryl hydrocarbon hydroxylase activity in rat nasal mucosa. J. Histochem. Cytochem. 41 (1993) 877-885
-
(1993)
J. Histochem. Cytochem.
, vol.41
, pp. 877-885
-
-
Voigt, J.M.1
Guengerich, F.P.2
Baron, J.3
-
37
-
-
0033786280
-
Induction of mouse CYP2J by pyrazole in the eye, kidney, liver, lung olfactory mucosa, and small intestine, but not in the heart
-
Xie Q., Zhang Q.-Y., Zhang Y., Su T., Gu J., Kaminsky L.S., and Ding X. Induction of mouse CYP2J by pyrazole in the eye, kidney, liver, lung olfactory mucosa, and small intestine, but not in the heart. Drug Metab. Dispos. 28 (2000) 1311-1316
-
(2000)
Drug Metab. Dispos.
, vol.28
, pp. 1311-1316
-
-
Xie, Q.1
Zhang, Q.-Y.2
Zhang, Y.3
Su, T.4
Gu, J.5
Kaminsky, L.S.6
Ding, X.7
-
38
-
-
0031869262
-
Effect of cigarette smoke on CYP1A1, CYP1A2 and CYP2B1/2 of nasal mucosa in F344 rats
-
Wardlaw S.A., Nikula K.J., Hracko D.A., Finch G.L., Thornton-Manning J.R., and Dahl A.R. Effect of cigarette smoke on CYP1A1, CYP1A2 and CYP2B1/2 of nasal mucosa in F344 rats. Carcinogenesis 19 (1998) 655-662
-
(1998)
Carcinogenesis
, vol.19
, pp. 655-662
-
-
Wardlaw, S.A.1
Nikula, K.J.2
Hracko, D.A.3
Finch, G.L.4
Thornton-Manning, J.R.5
Dahl, A.R.6
-
39
-
-
34548082616
-
Expression of constitutive androstane receptor, hepatic nuclear factor 4α, and P450 oxidoreductase genes determines interindividual variability in basal expression and activity of a broad scope of xenobiotic metabolism genes in the human liver
-
Wortham M., Czerwinki M.He., Parkinson A., and Wan Y.-J. Expression of constitutive androstane receptor, hepatic nuclear factor 4α, and P450 oxidoreductase genes determines interindividual variability in basal expression and activity of a broad scope of xenobiotic metabolism genes in the human liver. Drug. Metab. Dispos. 35. (2007) 1700-1710
-
(2007)
Drug. Metab. Dispos.
, vol.35
, pp. 1700-1710
-
-
Wortham, M.1
Czerwinki, M.He.2
Parkinson, A.3
Wan, Y.-J.4
-
40
-
-
0034708795
-
Identification and functional characterization of a conserved nuclear factor 1-like element in the proximal promotor region of CYP1A2 gene specifically expressed in the liver and olfactory mucosa
-
Zhang J., Zhang Q.-Y., Guo J., Zhou Y., and Ding X. Identification and functional characterization of a conserved nuclear factor 1-like element in the proximal promotor region of CYP1A2 gene specifically expressed in the liver and olfactory mucosa. J. Biol. Chem. 275 (2000) 8895-8902
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8895-8902
-
-
Zhang, J.1
Zhang, Q.-Y.2
Guo, J.3
Zhou, Y.4
Ding, X.5
-
41
-
-
0027141354
-
Risk factors for cancers of the nasal cavity and paranasal sinuses among white man in the United States
-
Zheng W., McLaughlin J.K., Chow W.H., Co Chien H.T., and Blot W.J. Risk factors for cancers of the nasal cavity and paranasal sinuses among white man in the United States. Am. J. Epidemiol. 138 (1993) 965-972
-
(1993)
Am. J. Epidemiol.
, vol.138
, pp. 965-972
-
-
Zheng, W.1
McLaughlin, J.K.2
Chow, W.H.3
Co Chien, H.T.4
Blot, W.J.5
|