Dried chicory root modifies the activity and expression of porcine hepatic CYP3A but not 2C - Effect of in vitro and in vivo exposure

Food and Chemical Toxicology

Volumn 50, Issue 11, 2012, Pages 4175-4179

  Rasmussen, Martin Krøyer ^a   Zamaratskaia, Galia ^b   Andersen, Bente ^a   Ekstrand, Bo ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Bioactive compounds; Boar taint; Chicory; Detoxification; Gender; Phase I metabolism

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 2C; CYTOCHROME P450 2C33; CYTOCHROME P450 3A; CYTOCHROME P450 3A29; MESSENGER RNA; PLANT EXTRACT; PREGNANE X RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHICORY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDING; FEMALE; GENE EXPRESSION REGULATION; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; LIVER MICROSOME; MALE; NONHUMAN; PLANT ROOT; PROTEIN EXPRESSION; SEX DIFFERENCE; SWINE; UPREGULATION;

ADMINISTRATION, ORAL; ANIMAL FEED; ANIMALS; CHICORY; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIVER; MALE; MICROSOMES, LIVER; PLANT EXTRACTS; PLANT ROOTS; RECEPTORS, ARYL HYDROCARBON; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; SUS SCROFA;

CICHORIUM INTYBUS; SUIDAE; SUS;

EID: 84866303627     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.08.024     Document Type: Article

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