3,5-Diiodo-l-thyronine induces SREBP-1 proteolytic cleavage block and apoptosis in human hepatoma (Hepg2) cells

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1831, Issue 12, 2013, Pages 1679-1689

  Rochira, Alessio ^a   Damiano, Fabrizio ^a   Marsigliante, Santo ^a   Gnoni, Gabriele V ^a   Siculella, Luisa ^a  

^a UNIVERSITY OF SALENTO   (Italy)

Author keywords

3,5 Diiodothyronine; Akt; Apoptosis; p38MAPK; PKC ; SREBP 1

Indexed keywords

3,5,3′-TRIIODO-L-THYRONINE; 3,5-DIIODO-L-THYRONINE; 3,5-DIIODOTHYRONINE; 4,6-DIAMIDINO-2-PHENYLINDOLE; AKT; APOPTOSIS; DAPI; ERK; EXTRACELLULAR SIGNAL-REGULATED KINASE; FASN; FATTY ACID SYNTHASE; FIREFLY LUCIFERASE; FL; INTERNAL RIBOSOME ENTRY SITE; IRES; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAPK; MITOGEN ACTIVATED PROTEIN KINASE; MTOR-C1; P38MAPK; PHOSPHOINOSITIDE 3-KINASE; PI3K; PKC; PKC-Δ; PROTEIN KINASE C; RENILLA LUCIFERASE; RL; SRB; SREBP; SREBP-1; STEROL REGULATORY ELEMENT BINDING PROTEIN; SULFORHODAMINE B; T2; T3; TH; THYROID HORMONE;

APOPTOSIS; DIIODOTHYRONINES; FATTY ACID SYNTHASE, TYPE I; GENE EXPRESSION REGULATION; HEP G2 CELLS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE C-DELTA; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIIODOTHYRONINE;

EID: 84884934209     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2013.08.003     Document Type: Article

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