메뉴 건너뛰기




Volumn 103, Issue 5, 2010, Pages 642-648

Quercetin induced apoptosis in association with death receptors and fludarabine in cells isolated from chronic lymphocytic leukaemia patients

Author keywords

apoptosis; CD95; chronic lymphocytic leukaemia; fludarabine; quercetin; TRAIL

Indexed keywords

CASPASE 3; CASPASE 9; DEATH RECEPTOR; FAS ANTIBODY; FLUDARABINE; LIPOCORTIN 5; QUERCETIN; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 77955982848     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605794     Document Type: Article
Times cited : (50)

References (40)
  • 1
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • Aggarwal BB, Shishodia S (2006) Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol 71(10): 1397-1421
    • (2006) Biochem Pharmacol , vol.71 , Issue.10 , pp. 1397-1421
    • Aggarwal, B.B.1    Shishodia, S.2
  • 2
    • 0027196985 scopus 로고
    • Fludarabine phosphate in chronic lymphoproliferative diseases
    • The French Group on CLL
    • Binet JL (1993) Fludarabine phosphate in chronic lymphoproliferative diseases. The French Group on CLL. Nouv Rev Fr Hematol 35(1): 5-7
    • (1993) Nouv Rev Fr Hematol , vol.35 , Issue.1 , pp. 5-7
    • Binet, J.L.1
  • 3
    • 55149104161 scopus 로고    scopus 로고
    • Quercetin: Potentials in the prevention and therapy of disease
    • Bischoff SC (2008) Quercetin: potentials in the prevention and therapy of disease. Curr Opin Clin Nutr Metab Care 11(6): 733-740
    • (2008) Curr Opin Clin Nutr Metab Care , vol.11 , Issue.6 , pp. 733-740
    • Bischoff, S.C.1
  • 5
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0037377562 scopus 로고    scopus 로고
    • Absorption of quercetin-3-glucoside and quercetin-4-glucoside in the rat small intestine: The role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter
    • Day AJ, Gee JM, DuPont MS, Johnson IT, Williamson G (2003) Absorption of quercetin-3-glucoside and quercetin-4-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter. Biochem Pharmacol 65(7): 1199-1206
    • (2003) Biochem Pharmacol , vol.65 , Issue.7 , pp. 1199-1206
    • Day, A.J.1    Gee, J.M.2    Dupont, M.S.3    Johnson, I.T.4    Williamson, G.5
  • 8
    • 2342453921 scopus 로고    scopus 로고
    • Death receptors in chemotherapy and cancer
    • Debatin KM, Krammer PH (2004) Death receptors in chemotherapy and cancer. Oncogene 23(16): 2950-2966
    • (2004) Oncogene , vol.23 , Issue.16 , pp. 2950-2966
    • Debatin, K.M.1    Krammer, P.H.2
  • 10
    • 0025768866 scopus 로고
    • Application of the neutral red assay (NR assay to monolayer cultures of primary hepatocytes: Rapid colorimetric viability determination for the unscheduled DNA synthesis test (UDS)
    • Fautz R, Husein B, Hechenberger C (1991) Application of the neutral red assay (NR assay) to monolayer cultures of primary hepatocytes: rapid colorimetric viability determination for the unscheduled DNA synthesis test (UDS). Mutat Res 253: 173-179
    • (1991) Mutat Res , vol.253 , pp. 173-179
    • Fautz, R.1    Husein, B.2    Hechenberger, C.3
  • 11
    • 0029999052 scopus 로고    scopus 로고
    • Phase i clinical trial of the flavonoid quercetin: Pharmacokinetics and evidence for in vivo tyrosine kinase inhibition
    • Ferry DR, Smith A, Malkhandi J, Fyfe DW, deTakats PG, Anderson D, Baker J, Kerr DJ (1996) Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. Clin Cancer Res 2(4): 659-668
    • (1996) Clin Cancer Res , vol.2 , Issue.4 , pp. 659-668
    • Ferry, D.R.1    Smith, A.2    Malkhandi, J.3    Fyfe, D.W.4    De Takats, P.G.5    Anderson, D.6    Baker, J.7    Kerr, D.J.8
  • 12
    • 41549124939 scopus 로고    scopus 로고
    • Chemoprevention of cancer by isothiocyanates and anthocyanins: Mechanisms of action and structure-activity relationship
    • Fimognari C, Lenzi M, Hrelia P (2008) Chemoprevention of cancer by isothiocyanates and anthocyanins: mechanisms of action and structure-activity relationship. Curr Med Chem 15(5): 440-447
    • (2008) Curr Med Chem , vol.15 , Issue.5 , pp. 440-447
    • Fimognari, C.1    Lenzi, M.2    Hrelia, P.3
  • 13
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
    • Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Dohner H, Hillmen P, Keating MJ, Montserrat E, Rai KR, Kipps TJ (2008) Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood 111(12): 5446-5456
    • (2008) Blood , vol.111 , Issue.12 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3    Caligaris-Cappio, F.4    Dighiero, G.5    Dohner, H.6    Hillmen, P.7    Keating, M.J.8    Montserrat, E.9    Rai, K.R.10    Kipps, T.J.11
  • 14
    • 34548812546 scopus 로고    scopus 로고
    • A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties
    • Harwood M, Danielewska-Nikiel B, Borzelleca JF, Flamm GW, Williams GM, Lines TC (2007) A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties. Food Chem Toxicol 45(11): 2179-2205
    • (2007) Food Chem Toxicol , vol.45 , Issue.11 , pp. 2179-2205
    • Harwood, M.1    Danielewska-Nikiel, B.2    Borzelleca, J.F.3    Flamm, G.W.4    Williams, G.M.5    Lines, T.C.6
  • 15
    • 0036547417 scopus 로고    scopus 로고
    • Death and anti-death: Tumour resistance to apoptosis
    • Igney FH, Krammer PH (2002) Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2(4): 277-288
    • (2002) Nat Rev Cancer , vol.2 , Issue.4 , pp. 277-288
    • Igney, F.H.1    Krammer, P.H.2
  • 16
    • 15844368449 scopus 로고    scopus 로고
    • Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and pre-dnisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia
    • The French Cooperative Group on CLL
    • Johnson S, Smith AG, Loffler H, Osby E, Juliusson G, Emmerich B, Wyld PJ, Hiddemann W (1996) Multicentre prospective randomised trial of fludarabine versus cyclophosphamide, doxorubicin, and pre-dnisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. The French Cooperative Group on CLL. Lancet 347(9013): 1432-1438
    • (1996) Lancet , vol.347 , Issue.9013 , pp. 1432-1438
    • Johnson, S.1    Smith, A.G.2    Loffler, H.3    Osby, E.4    Juliusson, G.5    Emmerich, B.6    Wyld, P.J.7    Hiddemann, W.8
  • 17
    • 28544439923 scopus 로고    scopus 로고
    • On the TRAIL of a new therapy for leukemia
    • Kaufmann SH, Steensma DP (2005) On the TRAIL of a new therapy for leukemia. Leukemia 19(12): 2195-2202
    • (2005) Leukemia , vol.19 , Issue.12 , pp. 2195-2202
    • Kaufmann, S.H.1    Steensma, D.P.2
  • 18
    • 57349169369 scopus 로고    scopus 로고
    • Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation
    • Kim JY, Kim EH, Park SS, Lim JH, Kwon TK, Choi KS (2008a) Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation. J Cell Biochem 105(6): 1386-1398
    • (2008) J Cell Biochem , vol.105 , Issue.6 , pp. 1386-1398
    • Kim, J.Y.1    Kim, E.H.2    Park, S.S.3    Lim, J.H.4    Kwon, T.K.5    Choi, K.S.6
  • 19
    • 42649100263 scopus 로고    scopus 로고
    • Quercetin augments TRAIL-induced apoptotic death: Involvement of the ERK signal transduction pathway
    • Kim YH, Lee DH, Jeong JH, Guo ZS, Lee YJ (2008b) Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway. Biochem Pharmacol 75(10): 1946-1958
    • (2008) Biochem Pharmacol , vol.75 , Issue.10 , pp. 1946-1958
    • Kim, Y.H.1    Lee, D.H.2    Jeong, J.H.3    Guo, Z.S.4    Lee, Y.J.5
  • 21
    • 0034202211 scopus 로고    scopus 로고
    • Antioxidants and cancer, part 3: Quercetin
    • Lamson DW, Brignall MS (2000) Antioxidants and cancer, part 3: quercetin. Altern Med Rev 5(3): 196-208
    • (2000) Altern Med Rev , vol.5 , Issue.3 , pp. 196-208
    • Lamson, D.W.1    Brignall, M.S.2
  • 23
    • 0037015675 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia
    • MacFarlane M, Harper N, Snowden RT, Dyer MJ, Barnett GA, Pringle JH, Cohen GM (2002) Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia. Oncogene 21(44): 6809-6818
    • (2002) Oncogene , vol.21 , Issue.44 , pp. 6809-6818
    • MacFarlane, M.1    Harper, N.2    Snowden, R.T.3    Dyer, M.J.4    Barnett, G.A.5    Pringle, J.H.6    Cohen, G.M.7
  • 25
    • 33846820580 scopus 로고    scopus 로고
    • Correlation of ZAP-70 expression in B cell leukemias to the ex vivo response to a combination of fludarabine/genistein
    • Mansour A, Chang VT, Srinivas S, Harrison J, Raveche E (2007) Correlation of ZAP-70 expression in B cell leukemias to the ex vivo response to a combination of fludarabine/genistein. Cancer Immunol Immunother 56(4): 501-514
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.4 , pp. 501-514
    • Mansour, A.1    Chang, V.T.2    Srinivas, S.3    Harrison, J.4    Raveche, E.5
  • 26
    • 51349127271 scopus 로고    scopus 로고
    • Multitargeted cancer prevention by quercetin
    • Murakami A, Ashida H, Terao J (2008) Multitargeted cancer prevention by quercetin. Cancer Lett 269(2): 315-325
    • (2008) Cancer Lett , vol.269 , Issue.2 , pp. 315-325
    • Murakami, A.1    Ashida, H.2    Terao, J.3
  • 27
    • 32944472519 scopus 로고    scopus 로고
    • Safety of quercetin for clinical application (Review)
    • Okamoto T (2005) Safety of quercetin for clinical application (Review). Int J Mol Med 16(2): 275-278
    • (2005) Int J Mol Med , vol.16 , Issue.2 , pp. 275-278
    • Okamoto, T.1
  • 28
    • 16444375702 scopus 로고    scopus 로고
    • Bodyguards and assassins: Bcl-2 family proteins and apoptosis control in chronic lymphocytic leukaemia
    • Packham G, Stevenson FK (2005) Bodyguards and assassins: Bcl-2 family proteins and apoptosis control in chronic lymphocytic leukaemia. Immunology 114(4): 441-449
    • (2005) Immunology , vol.114 , Issue.4 , pp. 441-449
    • Packham, G.1    Stevenson, F.K.2
  • 29
    • 58149456883 scopus 로고    scopus 로고
    • Death receptors as targets for anti-cancer therapy
    • Papenfuss K, Cordier SM, Walczak H (2008) Death receptors as targets for anti-cancer therapy. J Cell Mol Med 12(6B): 2566-2585
    • (2008) J Cell Mol Med , vol.12 , Issue.6 B , pp. 2566-2585
    • Papenfuss, K.1    Cordier, S.M.2    Walczak, H.3
  • 30
    • 70349562920 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of CLL: Novel therapeutic approaches
    • Pleyer L, Egle A, Hartmann TN, Greil R (2009) Molecular and cellular mechanisms of CLL: novel therapeutic approaches. Nat Rev Clin Oncol 6(7): 405-418
    • (2009) Nat Rev Clin Oncol , vol.6 , Issue.7 , pp. 405-418
    • Pleyer, L.1    Egle, A.2    Hartmann, T.N.3    Greil, R.4
  • 31
    • 34748906001 scopus 로고    scopus 로고
    • Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts
    • Psahoulia FH, Drosopoulos KG, Doubravska L, Andera L, Pintzas A (2007) Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts. Mol Cancer Ther 6(9): 2591-2599
    • (2007) Mol Cancer Ther , vol.6 , Issue.9 , pp. 2591-2599
    • Psahoulia, F.H.1    Drosopoulos, K.G.2    Doubravska, L.3    Andera, L.4    Pintzas, A.5
  • 32
    • 34447283477 scopus 로고    scopus 로고
    • Ins and outs of dietary phytochemicals in cancer chemoprevention
    • Russo GL (2007) Ins and outs of dietary phytochemicals in cancer chemoprevention. Biochem Pharmacol 74(4): 533-544
    • (2007) Biochem Pharmacol , vol.74 , Issue.4 , pp. 533-544
    • Russo, G.L.1
  • 33
    • 77954216210 scopus 로고    scopus 로고
    • Exploring death receptor pathways as selective targets in cancer therapy
    • Russo M, Mupo A, Spagnuolo C, Russo GL (2010) Exploring death receptor pathways as selective targets in cancer therapy. Biochem Pharmacol 8(5): 674-682
    • (2010) Biochem Pharmacol , vol.8 , Issue.5 , pp. 674-682
    • Russo, M.1    Mupo, A.2    Spagnuolo, C.3    Russo, G.L.4
  • 34
    • 34247626395 scopus 로고    scopus 로고
    • Quercetin enhances CD95-and TRAIL-induced apoptosis in leukemia cell lines
    • Russo M, Nigro P, Rosiello R, D'Arienzo R, Russo GL (2007) Quercetin enhances CD95-and TRAIL-induced apoptosis in leukemia cell lines. Leukemia 21(5): 1130-1133
    • (2007) Leukemia , vol.21 , Issue.5 , pp. 1130-1133
    • Russo, M.1    Nigro, P.2    Rosiello, R.3    D'Arienzo, R.4    Russo, G.L.5
  • 38
    • 65949095390 scopus 로고    scopus 로고
    • Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells
    • Siegelin MD, Reuss DE, Habel A, Rami A, von Deimling A (2009) Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells. Neuro Oncol 11(2): 122-131
    • (2009) Neuro Oncol , vol.11 , Issue.2 , pp. 122-131
    • Siegelin, M.D.1    Reuss, D.E.2    Habel, A.3    Rami, A.4    Von Deimling, A.5
  • 39
    • 77951494873 scopus 로고    scopus 로고
    • Targeted cancer therapies in the twenty-first century: Lessons from imatinib
    • Stegmeier F, Warmuth M, Sellers WR, Dorsch M (2010) Targeted cancer therapies in the twenty-first century: lessons from imatinib. Clin Pharmacol Ther 87(5): 543-552
    • (2010) Clin Pharmacol Ther , vol.87 , Issue.5 , pp. 543-552
    • Stegmeier, F.1    Warmuth, M.2    Sellers, W.R.3    Dorsch, M.4
  • 40
    • 33746833990 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia: Diagnosis and treatment
    • Yee KW, O'Brien SM (2006) Chronic lymphocytic leukemia: diagnosis and treatment. Mayo Clin Proc 81(8): 1105-1129
    • (2006) Mayo Clin Proc , vol.81 , Issue.8 , pp. 1105-1129
    • Yee, K.W.1    O'Brien, S.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.