Oregonin inhibits lipopolysaccharide-induced iNOS gene transcription and upregulates HO-1 expression in macrophages and microglia

British Journal of Pharmacology

Volumn 146, Issue 3, 2005, Pages 378-388

  Lee, Cheng Jui ^a   Lee, Shoei Sheng ^a   Chen, Su Chung ^a   Ho, Feng Ming ^b   Lin, Wan Wan ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAO YUAN GENERAL HOSPITAL   (Taiwan)

Author keywords

HO 1; iNOS; LPS; Macrophage; Microglia; Oregonin

Indexed keywords

1,7 BIS(3,4 DIHYDROXYPHENYL)HEPTAN 3 ONE 5 O BETA DEXTRO XYLOPYRANOSIDE; BACTERIUM LIPOPOLYSACCHARIDE; CARBON MONOXIDE; HEPTANE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROTEIN; PROTEIN HO 1; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ALDER; ALNUS FORMOSANA; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA BINDING; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE INDUCTION; GENETIC TRANSCRIPTION; IN VITRO STUDY; INHIBITION KINETICS; MACROPHAGE; MICROGLIA; NONHUMAN; PHARMACOGENETICS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

ALNUS; ANIMALS; CELL LINE; DIARYLHEPTANOIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICROGLIA; NF-KAPPA B; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TRANSCRIPTION FACTOR AP-1;

EID: 27144480129     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706336     Document Type: Article

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