Cinacalcet, a calcimimetic, prevents nonsteroidalantiinflammatory drug-induced small intestinal damage in rats

Journal of Physiology and Pharmacology

Volumn 64, Issue 4, 2013, Pages 453-463

  Hayashi, S ^a   Kurata, N ^a   Kitahirachi, E ^a   Nishimura, Y ^a   Amagase, K ^a   Yano, T ^b   Takeuchi, Koji ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b EA Pharma Co   (Japan)

Author keywords

Calcium sensing receptor; Cinacalcet; Inducible nitric oxide synthase; Intestinal damage; Loxoprofen induced enteropathy; Myeloperoxidase; Tumor necrosis factor alpha

Indexed keywords

CALCIMIMETIC AGENT; CALCIUM SENSING RECEPTOR; CINACALCET; GAMMA GLUTAMYLVALYLGLYCINE; INDUCIBLE NITRIC OXIDE SYNTHASE; LOXOPROFEN; MUCIN 2; MYELOPEROXIDASE; NONSTEROID ANTIINFLAMMATORY AGENT; POLYPEPTIDE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; DRUG MECHANISM; DRUG RESPONSE; ENTEROBACTERIACEAE; ENTEROPATHY; ENZYME ACTIVITY; INTESTINAL DYSMOTILITY; INTESTINE INJURY; INTESTINE MUCOSA; INTESTINE ULCER; MALE; MUCUS SECRETION; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; RAT; SECRETION (PROCESS); SMALL INTESTINE HEMORRHAGE; SPRAGUE DAWLEY RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BACTERIAL LOAD; DINOPROSTONE; ENTEROBACTERIACEAE; INTESTINAL DISEASES; INTESTINE, SMALL; MALE; MUCIN-2; NAPHTHALENES; NITRIC OXIDE SYNTHASE TYPE II; OLIGOPEPTIDES; PEROXIDASE; PHENYLPROPIONATES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CALCIUM-SENSING; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84884913917     PISSN: 08675910     EISSN: 18991505     Source Type: Journal    
DOI: None     Document Type: Article

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