The Stomach Divalent Ion-sensing Receptor SCAR Is a Modulator of Gastric Acid Secretion

Journal of Biological Chemistry

Volumn 276, Issue 43, 2001, Pages 39549-39552

  Geibel, John P ^a   Wagner, Carsten A ^a   Caroppo, Rosa ^a,b   Qureshi, Imtiaz ^a   Gloeckner, Judith ^a   Manuelidis, Laura ^a   Kirchhoff, Philipp ^a   Radebold, Klaus ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; BIOLOGICAL ORGANS; CELLS; ORGANIC ACIDS; POSITIVE IONS; TISSUE;

ACID SECRETION;

BIOCHEMISTRY;

ACETYLCHOLINE; CALCIUM ION; CALCIUM SENSING RECEPTOR; CARRIER PROTEIN; DIVALENT CATION; GADOLINIUM; GASTRIN; HISTAMINE; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; MAGNESIUM ION; OMEPRAZOLE; STOMACH CALCIUM SENSING RECEPTOR; UNCLASSIFIED DRUG; ANTIULCER AGENT; CALCIUM; CELL SURFACE RECEPTOR; CIMETIDINE; EXTRACELLULAR CALCIUM CATION SENSING RECEPTOR, RAT; EXTRACELLULAR CALCIUM CATION-SENSING RECEPTOR, RAT; HISTAMINE H2 RECEPTOR ANTAGONIST; ISOPROTEIN; MAGNESIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; BRAIN FUNCTION; CELL MEMBRANE; CONTROLLED STUDY; ENDOCRINE FUNCTION; NONHUMAN; PRIORITY JOURNAL; RAT; REDUCTION; REGULATORY MECHANISM; SECRETORY CELL; STOMACH ACID SECRETION; STOMACH GLAND; STOMACH PARIETAL CELL; ANIMAL; METABOLISM; SECRETION; SPRAGUE DAWLEY RAT; STOMACH ACID; STOMACH MUCOSA;

ANIMALIA;

ANIMALS; ANTI-ULCER AGENTS; CALCIUM; CATIONS, DIVALENT; CIMETIDINE; GASTRIC ACID; GASTRIC MUCOSA; H(+)-K(+)-EXCHANGING ATPASE; HISTAMINE; HISTAMINE H2 ANTAGONISTS; MAGNESIUM; OMEPRAZOLE; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CALCIUM-SENSING; RECEPTORS, CELL SURFACE;

EID: 0035955704     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M107315200     Document Type: Article

References (22)

1. Hersey, S. J. & Sachs, G. (1995) Physiol. Rev. 75, 155-189
2. Geibel, J., Abraham, R., Modlin, I. & Sachs, G. (1995) Gastroenterology 109, 1060-1067
3. Sachs, J. (1997) Pharmacotherapy 17, 22-37
4. Chew, C. S. (1986) Am. J. Physiol. 250, G814-G823
5. Cheng, I., Qureshi, I., Chattopadhyh, N., Qureshi, A., Butters, R. S., Hall, A. E., Cima, R. R., Rogers, K. V., Hebert, S. C., Geibel, J. P., Brown, E. M. & Soybel, D. I. (1999) Gastroenterology 116, 118-126
6. Hofer, A. M., Curci, S., Doble, M. A., Brown, E. M. & Soybel, D. I. (2000) Nat. Cell. Biol. 2, 392-398
7. Paradiso, A., Townsley, M., Wenzl, E. & Machen, T. (1989) Am. J. Physiol. 257, C554-C561
8. Boron, J. H. (2000) Mt. Sinai J. Med. 67, 37-40
9. Black, J. W., Duncan, W. A., Durant, C. J., Ganellin, C. R. & Parsons, E. M. (1972) Nature 236, 385-390
10. Lindberg, P., Brandstrom, A., Wallmark, B., Mattsson, H., Rikner, L. & Hoffmann, K. J. (1990) Med. Res. Rev. 10, 1-54
11. Waisbren, S. J., Geibel, J., Boron, W. F. & Modlin, I. M. (1994) Am. J. Physiol. 266, C1013-C1027
12. Singh, S. K., Binder, H. J., Geibel, J. P. & Boron, W. F. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 11573-11577
13. Swarts, H. P., Klaassen, C. H. & De Pont J. J. (1997) Ann. N. Y. Acad. Sci. 834, 472-474
14. Courtois-Coutry, C. C. (1997) Cell 90, 501-510
15. Noel, J. & Pouyssegur, J. (1995) Am. J. Physiol. 268, C283-C296
16. Yun, C. H., Tse, C. M., Nath, S. K., Levine, S. A., Brant, S. R. & Donowitz, M. (1995) Am. J. Physiol. 269, G1-G11
17. Caroppo, R., Schmitt, B. M., Boron, W. F. & Geibel, J. P. (1998) Gastroenterology 114, G4635
18. Rossmann, H., Bachmann, O., Vieillard-Baron, D., Gregor, M. & Seidler, U. (1999) Gastroenterology 116, 1389-1398
19. Negulescu, P. A. & Machen, T. E. (1995) Am. J. Physiol. 269, G770-G778
20. Conigrave, A. D., Quinn, S. J. & Brown, E. M. (2000) Proc. Natl. Acad. Sci. U. S. A. 25, 4814-4819
21. Wise, S. R., Quigley, M., Saxe, A. W. & Zdon M. J. (1990) Surgery 108, 1058-1063
22. Favus, M. J., Bushinsky, D. A. & Coe, F. L. (1986) Am. J. Physiol. 251, G695-G700