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Volumn 250, Issue 5, 2013, Pages 965-983

CEP proteins: The knights of centrosome dynasty

Author keywords

Cancer; Centrioles; Centrosomes; CEP family; Primary microcephaly

Indexed keywords

NUCLEAR PROTEIN;

EID: 84884910067     PISSN: 0033183X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00709-013-0488-9     Document Type: Review
Times cited : (82)

References (116)
  • 1
    • 0346874342 scopus 로고    scopus 로고
    • Proteomic characterization of the human centrosome by protein correlation profiling
    • Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, Mann M (2003) Proteomic characterization of the human centrosome by protein correlation profiling. Nature 426: 570-574.
    • (2003) Nature , vol.426 , pp. 570-574
    • Andersen, J.S.1    Wilkinson, C.J.2    Mayor, T.3    Mortensen, P.4    Nigg, E.A.5    Mann, M.6
  • 2
    • 33847370317 scopus 로고    scopus 로고
    • Functional genomics in Trypanosoma brucei identifies evolutionarily conserved components of motile flagella
    • Baron DM, Ralston KS, Kabututu ZP, Hill KL (2007) Functional genomics in Trypanosoma brucei identifies evolutionarily conserved components of motile flagella. J Cell Sci 120: 478-491.
    • (2007) J Cell Sci , vol.120 , pp. 478-491
    • Baron, D.M.1    Ralston, K.S.2    Kabututu, Z.P.3    Hill, K.L.4
  • 3
    • 77950566340 scopus 로고    scopus 로고
    • CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response
    • Barr AR et al (2010) CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response. J Cell Biol 189: 23-39.
    • (2010) J Cell Biol , vol.189 , pp. 23-39
    • Barr, A.R.1
  • 4
    • 44649117902 scopus 로고    scopus 로고
    • Centrosome amplification can initiate tumorigenesis in flies
    • Basto R et al (2008) Centrosome amplification can initiate tumorigenesis in flies. Cell 133: 1032-1042.
    • (2008) Cell , vol.133 , pp. 1032-1042
    • Basto, R.1
  • 5
    • 20144386602 scopus 로고    scopus 로고
    • A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size
    • Bond J et al (2005) A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size. Nat Genet 37: 353-355.
    • (2005) Nat Genet , vol.37 , pp. 353-355
    • Bond, J.1
  • 7
    • 33644858832 scopus 로고    scopus 로고
    • Flagellar motility is required for the viability of the bloodstream trypanosome
    • Broadhead R et al (2006) Flagellar motility is required for the viability of the bloodstream trypanosome. Nature 2006(440): 224-227.
    • (2006) Nature , vol.2006 , Issue.440 , pp. 224-227
    • Broadhead, R.1
  • 8
    • 32044457901 scopus 로고    scopus 로고
    • The transcripts of SFRP1, CEP63 and EIF4G2 genes are frequently downregulated in transitional cell carcinomas of the bladder
    • Buim ME, Soares FA, Sarkis AS, Nagai MA (2005) The transcripts of SFRP1, CEP63 and EIF4G2 genes are frequently downregulated in transitional cell carcinomas of the bladder. Oncology 69: 445-454.
    • (2005) Oncology , vol.69 , pp. 445-454
    • Buim, M.E.1    Soares, F.A.2    Sarkis, A.S.3    Nagai, M.A.4
  • 9
    • 49649092093 scopus 로고    scopus 로고
    • Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability
    • Castellanos E et al (2008) Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability. Curr Biol 18: 1209-1214.
    • (2008) Curr Biol , vol.18 , pp. 1209-1214
    • Castellanos, E.1
  • 10
    • 34248231106 scopus 로고    scopus 로고
    • Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics
    • Chen N et al (2006) Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics. Genome Biol 7: R126.
    • (2006) Genome Biol , vol.7
    • Chen, N.1
  • 11
    • 78650115459 scopus 로고    scopus 로고
    • CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex
    • Choi Y et al (2010) CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex. J Cell Biol 191: 1089-1095.
    • (2010) J Cell Biol , vol.191 , pp. 1089-1095
    • Choi, Y.1
  • 12
    • 78349263512 scopus 로고    scopus 로고
    • Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
    • Cizmecioglu O et al (2010) Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome. J Cell Biol 191: 731-739.
    • (2010) J Cell Biol , vol.191 , pp. 731-739
    • Cizmecioglu, O.1
  • 13
    • 80051938700 scopus 로고    scopus 로고
    • Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens
    • Cooper CD et al (2011) Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens. PLoS One 6: e23916.
    • (2011) PLoS One , vol.6
    • Cooper, C.D.1
  • 14
    • 54749133489 scopus 로고    scopus 로고
    • A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila
    • Dobbelaere J, Josue F, Suijkerbuijk S, Baum B, Tapon N, Raff J (2008) A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila. PLoS Biol 6: e224.
    • (2008) PLoS Biol , vol.6
    • Dobbelaere, J.1    Josue, F.2    Suijkerbuijk, S.3    Baum, B.4    Tapon, N.5    Raff, J.6
  • 15
  • 16
    • 38949218018 scopus 로고    scopus 로고
    • Analysis of centrosome overduplication in correlation to cell division errors in high-risk human papillomavirus (HPV)-associated anal neoplasms
    • Duensing A et al (2008) Analysis of centrosome overduplication in correlation to cell division errors in high-risk human papillomavirus (HPV)-associated anal neoplasms. Virology 372: 157-164.
    • (2008) Virology , vol.372 , pp. 157-164
    • Duensing, A.1
  • 17
    • 77957982182 scopus 로고    scopus 로고
    • Asterless is a scaffold for the onset of centriole assembly
    • Dzhindzhev NS et al (2010) Asterless is a scaffold for the onset of centriole assembly. Nature 467: 714-718.
    • (2010) Nature , vol.467 , pp. 714-718
    • Dzhindzhev, N.S.1
  • 19
    • 34548274888 scopus 로고    scopus 로고
    • Xenopus Cep57 Is a novel kinetochore component involved in microtubule attachment
    • Emanuele MJ, Stukenberg PT (2007) Xenopus Cep57 Is a novel kinetochore component involved in microtubule attachment. Cell 130: 893-905.
    • (2007) Cell , vol.130 , pp. 893-905
    • Emanuele, M.J.1    Stukenberg, P.T.2
  • 20
    • 26444544501 scopus 로고    scopus 로고
    • Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis
    • Fabro M et al (2005) Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis. Dev Cell 9: 477-488.
    • (2005) Dev Cell , vol.9 , pp. 477-488
    • Fabro, M.1
  • 21
    • 38749152785 scopus 로고    scopus 로고
    • CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the g-tubulin ring complex
    • Fong KW, Choi YK, Rattner JB, Qi RZ (2008) CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the g-tubulin ring complex. Mol Biol Cell 19: 115-125.
    • (2008) Mol Biol Cell , vol.19 , pp. 115-125
    • Fong, K.W.1    Choi, Y.K.2    Rattner, J.B.3    Qi, R.Z.4
  • 22
    • 77953276042 scopus 로고    scopus 로고
    • Clustering phenotype populations by genome-wide RNAi and multiparametric imaging
    • Fuchs F et al (2010) Clustering phenotype populations by genome-wide RNAi and multiparametric imaging. Mol Syst Biol 6: 370.
    • (2010) Mol Syst Biol , vol.6 , pp. 370
    • Fuchs, F.1
  • 23
    • 62849100950 scopus 로고    scopus 로고
    • FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation
    • Gemenetzidis E et al (2009) FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation. PLoS One 4(3): e4849.
    • (2009) PLoS One , vol.4 , Issue.3
    • Gemenetzidis, E.1
  • 24
    • 51149112302 scopus 로고    scopus 로고
    • Multiple centrosomes: together they stand, divided they fall
    • Gergely F, Basto R (2008) Multiple centrosomes: together they stand, divided they fall. Genes Dev 22: 2291-2296.
    • (2008) Genes Dev , vol.22 , pp. 2291-2296
    • Gergely, F.1    Basto, R.2
  • 25
    • 67650150099 scopus 로고    scopus 로고
    • Improving structure-based function prediction using molecular dynamics
    • Glazer DS, Radmer RJ, Altman RB (2009) Improving structure-based function prediction using molecular dynamics. Structure 17: 919-929.
    • (2009) Structure , vol.17 , pp. 919-929
    • Glazer, D.S.1    Radmer, R.J.2    Altman, R.B.3
  • 26
    • 56949084012 scopus 로고    scopus 로고
    • Centrosome function during stem cell division: the devil is in the details
    • Gonzalez C (2008) Centrosome function during stem cell division: the devil is in the details. Curr Opin Cell Biol 20: 694-698.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 694-698
    • Gonzalez, C.1
  • 28
    • 38349078475 scopus 로고    scopus 로고
    • Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion
    • Graser S et al (2007a) Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion. J Cell Sci 120: 4321-4331.
    • (2007) J Cell Sci , vol.120 , pp. 4321-4331
    • Graser, S.1
  • 29
    • 35548974826 scopus 로고    scopus 로고
    • Cep164, a novel centriole appendage protein required for primary cilium formation
    • Graser S et al (2007b) Cep164, a novel centriole appendage protein required for primary cilium formation. J Cell Biol 179: 321-330.
    • (2007) J Cell Biol , vol.179 , pp. 321-330
    • Graser, S.1
  • 30
    • 14844293128 scopus 로고    scopus 로고
    • The forkhead-associated domain protein Cep170 interacts with polo-like kinase 1 and serves as a marker for mature centrioles
    • Guarguaglini G et al (2005) The forkhead-associated domain protein Cep170 interacts with polo-like kinase 1 and serves as a marker for mature centrioles. Mol Biol Cell 16: 1095-1107.
    • (2005) Mol Biol Cell , vol.16 , pp. 1095-1107
    • Guarguaglini, G.1
  • 31
    • 77955068270 scopus 로고    scopus 로고
    • Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4
    • Guernsey DL et al (2010) Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4. Am J Hum Genet 87: 40-51.
    • (2010) Am J Hum Genet , vol.87 , pp. 40-51
    • Guernsey, D.L.1
  • 32
    • 34748827404 scopus 로고    scopus 로고
    • The ups and downs of neural progenitors: Cep120 and TACCs control interkinetic nuclear migration
    • Guerrier S, Polleux F (2007) The ups and downs of neural progenitors: Cep120 and TACCs control interkinetic nuclear migration. Neuron 56: 1-3.
    • (2007) Neuron , vol.56 , pp. 1-3
    • Guerrier, S.1    Polleux, F.2
  • 33
    • 40349089148 scopus 로고    scopus 로고
    • Analysis of the cellular centrosome in fine-needle aspirations of the breast
    • Guo HQ et al (2007) Analysis of the cellular centrosome in fine-needle aspirations of the breast. Breast Canc Res 9: R48.
    • (2007) Breast Canc Res , vol.9
    • Guo, H.Q.1
  • 34
    • 84867772494 scopus 로고    scopus 로고
    • New insights into subcomplex assembly and modifications of centrosomal proteins
    • Habermann K, Lange BM (2012) New insights into subcomplex assembly and modifications of centrosomal proteins. Cell Div 7(1): 17.
    • (2012) Cell Div , vol.7 , Issue.1 , pp. 17
    • Habermann, K.1    Lange, B.M.2
  • 35
    • 38949099775 scopus 로고    scopus 로고
    • A syndromic form of autosomal recessive congenital microcephaly (Jawad syndrome) maps to chromosome 18p11.22-q11.2
    • Hassan MJ, Chishti MS, Jamal SM, Tariq M, Ahmad W (2008) A syndromic form of autosomal recessive congenital microcephaly (Jawad syndrome) maps to chromosome 18p11. 22-q11. 2. Hum Genet 123: 77-82.
    • (2008) Hum Genet , vol.123 , pp. 77-82
    • Hassan, M.J.1    Chishti, M.S.2    Jamal, S.M.3    Tariq, M.4    Ahmad, W.5
  • 36
    • 34547113772 scopus 로고    scopus 로고
    • High rate of centrosome aberrations and correlation with proliferative activity in patients with untreated B-cell chronic lymphocytic leukemia
    • Hensel M et al (2007) High rate of centrosome aberrations and correlation with proliferative activity in patients with untreated B-cell chronic lymphocytic leukemia. Int J Cancer 121: 978-983.
    • (2007) Int J Cancer , vol.121 , pp. 978-983
    • Hensel, M.1
  • 37
    • 0035873385 scopus 로고    scopus 로고
    • "It takes two to tango": understanding how centrosome duplication is regulated throughout the cell cycle
    • Hinchcliffe EH, Sluder G (2001) "It takes two to tango": understanding how centrosome duplication is regulated throughout the cell cycle. Genes Dev 15: 1167-1181.
    • (2001) Genes Dev , vol.15 , pp. 1167-1181
    • Hinchcliffe, E.H.1    Sluder, G.2
  • 38
    • 35548937762 scopus 로고    scopus 로고
    • Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex
    • Hoppeler-Lebel A et al (2007) Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex. J Cell Sci 120: 3299-3308.
    • (2007) J Cell Sci , vol.120 , pp. 3299-3308
    • Hoppeler-Lebel, A.1
  • 39
    • 84860757548 scopus 로고    scopus 로고
    • A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function
    • Hussain MS et al (2012) A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function. Am J Hum Genet 90: 871-878.
    • (2012) Am J Hum Genet , vol.90 , pp. 871-878
    • Hussain, M.S.1
  • 40
    • 1642564276 scopus 로고    scopus 로고
    • To beat or not to beat: roles of cilia in development and disease
    • Ibañez-Tallon I, Heintz N, Omran H (2003) To beat or not to beat: roles of cilia in development and disease. Hum Mol Genet 12: R27-R35.
    • (2003) Hum Mol Genet , vol.12
    • Ibañez-Tallon, I.1    Heintz, N.2    Omran, H.3
  • 41
    • 84859792763 scopus 로고    scopus 로고
    • Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2: structure-activity relationship, structural biology, and cellular activity
    • Innocent P et al (2012) Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2: structure-activity relationship, structural biology, and cellular activity. J Med Chem 5: 3228-3241.
    • (2012) J Med Chem , vol.5 , pp. 3228-3241
    • Innocent, P.1
  • 42
    • 65349106268 scopus 로고    scopus 로고
    • Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma
    • Inoda S et al (2009) Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma. J Immunother 32: 474-485.
    • (2009) J Immunother , vol.32 , pp. 474-485
    • Inoda, S.1
  • 43
    • 78650705927 scopus 로고    scopus 로고
    • The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma
    • Inoda S et al (2011) The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma. Exp Mol Pathol 90: 55-60.
    • (2011) Exp Mol Pathol , vol.90 , pp. 55-60
    • Inoda, S.1
  • 44
    • 77950675984 scopus 로고    scopus 로고
    • TEX14 interacts with CEP55 to block cell abscission
    • Iwamori T et al (2010) TEX14 interacts with CEP55 to block cell abscission. Mol Cell Biol 30: 2280-2292.
    • (2010) Mol Cell Biol , vol.30 , pp. 2280-2292
    • Iwamori, T.1
  • 45
    • 79955009072 scopus 로고    scopus 로고
    • Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods
    • Jakobsen L et al (2011) Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. EMBO J 30(8): 1520-1535.
    • (2011) EMBO J , vol.30 , Issue.8 , pp. 1520-1535
    • Jakobsen, L.1
  • 46
    • 78651248502 scopus 로고    scopus 로고
    • CEP152 is a genome maintenance protein disrupted in Seckel syndrome
    • Kalay E et al (2011) CEP152 is a genome maintenance protein disrupted in Seckel syndrome. Nat Genet 43: 23-26.
    • (2011) Nat Genet , vol.43 , pp. 23-26
    • Kalay, E.1
  • 47
    • 40049087659 scopus 로고    scopus 로고
    • Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer
    • Kang JU, Koo SH, Kwon KC, Park JW, Kim JM (2008) Gain at chromosomal region 5p15. 33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer. Canc Genet Cytogenet 182: 1-11.
    • (2008) Canc Genet Cytogenet , vol.182 , pp. 1-11
    • Kang, J.U.1    Koo, S.H.2    Kwon, K.C.3    Park, J.W.4    Kim, J.M.5
  • 48
    • 0034605123 scopus 로고    scopus 로고
    • Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5
    • Kapoor TM, Mayer TU, Coughlin ML, Mitchison TJ (2000) Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. J Cell Biol 150: 975-988.
    • (2000) J Cell Biol , vol.150 , pp. 975-988
    • Kapoor, T.M.1    Mayer, T.U.2    Coughlin, M.L.3    Mitchison, T.J.4
  • 49
    • 20544436245 scopus 로고    scopus 로고
    • Proteomic analysis of isolated Chlamydomonas centrioles reveals orthologs of ciliary-disease genes
    • Keller LC, Romijn EP, Zamora I, Yates JR 3rd, Marshall WF (2005) Proteomic analysis of isolated Chlamydomonas centrioles reveals orthologs of ciliary-disease genes. Curr Biol 15: 1090-1098.
    • (2005) Curr Biol , vol.15 , pp. 1090-1098
    • Keller, L.C.1    Romijn, E.P.2    Zamora, I.3    Yates 3rd, J.R.4    Marshall, W.F.5
  • 50
    • 0033971720 scopus 로고    scopus 로고
    • Centrosome-independent mitotic spindle formation in vertebrates
    • Khodjakov A, Cole RW, Oakley BR, Rieder CL (2000) Centrosome-independent mitotic spindle formation in vertebrates. Curr Biol 10: 59-67.
    • (2000) Curr Biol , vol.10 , pp. 59-67
    • Khodjakov, A.1    Cole, R.W.2    Oakley, B.R.3    Rieder, C.L.4
  • 51
    • 79551536310 scopus 로고    scopus 로고
    • The pericentriolar satellite protein CEP90 is crucial for integrity of the mitotic spindle pole
    • Kim K, Rhee K (2011) The pericentriolar satellite protein CEP90 is crucial for integrity of the mitotic spindle pole. J Cell Sci 124: 338-347.
    • (2011) J Cell Sci , vol.124 , pp. 338-347
    • Kim, K.1    Rhee, K.2
  • 52
    • 56249109443 scopus 로고    scopus 로고
    • A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization
    • Kim K, Lee S, Chang J, Rhee K (2008) A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization. Exp Cell Res 314: 3692-3700.
    • (2008) Exp Cell Res , vol.314 , pp. 3692-3700
    • Kim, K.1    Lee, S.2    Chang, J.3    Rhee, K.4
  • 54
    • 79952577220 scopus 로고    scopus 로고
    • Mutations in the TSGA14 gene in families with autism spectrum disorders
    • Korvatska O et al (2011) Mutations in the TSGA14 gene in families with autism spectrum disorders. Am J Med Genet B Neuropsychiatr Genet 156B: 303-311.
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.156 B , pp. 303-311
    • Korvatska, O.1
  • 55
    • 10744221244 scopus 로고    scopus 로고
    • Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma
    • Kramer A et al (2003) Centrosome aberrations as a possible mechanism for chromosomal instability in non-Hodgkin's lymphoma. Leukemia 17: 2207-2213.
    • (2003) Leukemia , vol.17 , pp. 2207-2213
    • Kramer, A.1
  • 56
    • 84861790146 scopus 로고    scopus 로고
    • Computational investigation of pathogenic nsSNPs in CEP63 protein
    • Kumar A, Purohit R (2012a) Computational investigation of pathogenic nsSNPs in CEP63 protein. Gene 503: 75-82.
    • (2012) Gene , vol.503 , pp. 75-82
    • Kumar, A.1    Purohit, R.2
  • 57
    • 84867629652 scopus 로고    scopus 로고
    • Computational centrosomics: an approach to understand the dynamic behaviour of centrosome
    • Kumar A, Purohit R (2012b) Computational centrosomics: an approach to understand the dynamic behaviour of centrosome. Gene 511(1): 125-126.
    • (2012) Gene , vol.511 , Issue.1 , pp. 125-126
    • Kumar, A.1    Purohit, R.2
  • 58
    • 84872270918 scopus 로고    scopus 로고
    • Computational screening and molecular dynamics simulation of disease associated nsSNPs in CENP-E
    • doi: 10. 1016/j. mrfmmm. 2012. 08. 005
    • Kumar A, Purohit R (2012c) Computational screening and molecular dynamics simulation of disease associated nsSNPs in CENP-E. Mutat Res 738-739: 28-37. doi: 10. 1016/j. mrfmmm. 2012. 08. 005.
    • (2012) Mutat Res , vol.738-739 , pp. 28-37
    • Kumar, A.1    Purohit, R.2
  • 59
    • 84890039938 scopus 로고    scopus 로고
    • Insight into Nek2A activity regulation and its pharmacological prospects
    • doi: 10. 1016/j. ejmhg. 2012. 10. 006
    • Kumar A et al (2012) Insight into Nek2A activity regulation and its pharmacological prospects. Egypt J Med Hum Genet. doi: 10. 1016/j. ejmhg. 2012. 10. 006.
    • (2012) Egypt J Med Hum Genet
    • Kumar, A.1
  • 60
    • 84863598108 scopus 로고    scopus 로고
    • Bioinformatics and variability in drug response: a protein structural perspective
    • Lahti JL et al (2012) Bioinformatics and variability in drug response: a protein structural perspective. J R Soc Interface 9: 1409-1437.
    • (2012) J R Soc Interface , vol.9 , pp. 1409-1437
    • Lahti, J.L.1
  • 61
    • 0036468701 scopus 로고    scopus 로고
    • Integration of the centrosome in cell cycle control, stress response and signal transduction pathways
    • Lange BM (2002) Integration of the centrosome in cell cycle control, stress response and signal transduction pathways. Curr Opin Cell Biol 14: 35-43.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 35-43
    • Lange, B.M.1
  • 62
    • 77955615631 scopus 로고    scopus 로고
    • Proteins required for centrosome clustering in cancer cells
    • Leber B et al (2010) Proteins required for centrosome clustering in cancer cells. Sci Transl Med 2: 33-38.
    • (2010) Sci Transl Med , vol.2 , pp. 33-38
    • Leber, B.1
  • 63
    • 54949088988 scopus 로고    scopus 로고
    • Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55
    • Lee HH, Elia N, Ghirlando R, Lippincott-Schwartz J, Hurley JH (2008) Midbody targeting of the ESCRT machinery by a noncanonical coiled coil in CEP55. Science 322: 576-580.
    • (2008) Science , vol.322 , pp. 576-580
    • Lee, H.H.1    Elia, N.2    Ghirlando, R.3    Lippincott-Schwartz, J.4    Hurley, J.H.5
  • 64
    • 84862776744 scopus 로고    scopus 로고
    • CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium
    • Lee JE et al (2012) CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium. Nat Genet 44: 193-199.
    • (2012) Nat Genet , vol.44 , pp. 193-199
    • Lee, J.E.1
  • 65
    • 2342501364 scopus 로고    scopus 로고
    • Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene
    • Li JB et al (2004) Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene. Cell 2004(117): 541-552.
    • (2004) Cell , vol.2004 , Issue.117 , pp. 541-552
    • Li, J.B.1
  • 66
    • 2642585189 scopus 로고    scopus 로고
    • Homology-based functional proteomics by mass spectrometry: application to the Xenopus microtubule-associated proteome
    • Liska AJ, Popov AV, Sunyaev S, Coughlin P, Habermann B, Shevchenko A, Bork P, Karsenti E (2004) Homology-based functional proteomics by mass spectrometry: application to the Xenopus microtubule-associated proteome. Proteomics 4: 2707-2721.
    • (2004) Proteomics , vol.4 , pp. 2707-2721
    • Liska, A.J.1    Popov, A.V.2    Sunyaev, S.3    Coughlin, P.4    Habermann, B.5    Shevchenko, A.6    Bork, P.7    Karsenti, E.8
  • 68
    • 77952201222 scopus 로고    scopus 로고
    • Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors
    • Lizarraga SB et al (2010) Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development 137: 1907-1917.
    • (2010) Development , vol.137 , pp. 1907-1917
    • Lizarraga, S.B.1
  • 69
    • 79952758980 scopus 로고    scopus 로고
    • Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance
    • Löffler H et al (2011) Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance. Cancer Res 71: 2129-2139.
    • (2011) Cancer Res , vol.71 , pp. 2129-2139
    • Löffler, H.1
  • 70
    • 79958121228 scopus 로고    scopus 로고
    • Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome
    • Madeline AL et al (2011) Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome. Nat Med 17: 726-731.
    • (2011) Nat Med , vol.17 , pp. 726-731
    • Madeline, A.L.1
  • 71
    • 30944469794 scopus 로고    scopus 로고
    • The novel centrosomal associated protein CEP55 is present in the spindle midzone and the midbody
    • Martinez-Garay I et al (2006) The novel centrosomal associated protein CEP55 is present in the spindle midzone and the midbody. Genomics 87: 243-253.
    • (2006) Genomics , vol.87 , pp. 243-253
    • Martinez-Garay, I.1
  • 72
    • 0035936578 scopus 로고    scopus 로고
    • Zygotic development without functional mitotic centrosomes
    • Megraw TL, Kao LR, Kaufman T (2001) Zygotic development without functional mitotic centrosomes. Curr Biol 11: 116-120.
    • (2001) Curr Biol , vol.11 , pp. 116-120
    • Megraw, T.L.1    Kao, L.R.2    Kaufman, T.3
  • 73
    • 0034753402 scopus 로고    scopus 로고
    • Centrosome cohesion is regulated by a balance of kinase and phosphatase activities
    • Meraldi P, Nigg EA (2001) Centrosome cohesion is regulated by a balance of kinase and phosphatase activities. J Cell Sci 114: 3749-3757.
    • (2001) J Cell Sci , vol.114 , pp. 3749-3757
    • Meraldi, P.1    Nigg, E.A.2
  • 74
    • 35348896591 scopus 로고    scopus 로고
    • The Chlamydomonas genome reveals the evolution of key animal and plant functions
    • Merchant SS et al (2007) The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science 2007(318): 245-250.
    • (2007) Science , vol.2007 , Issue.318 , pp. 245-250
    • Merchant, S.S.1
  • 75
    • 77957810181 scopus 로고    scopus 로고
    • Proteomic and functional analysis of the mitotic Drosophila centrosome
    • Müller H et al (2010) Proteomic and functional analysis of the mitotic Drosophila centrosome. EMBO J 2010(29): 3344-3357.
    • (2010) EMBO J , vol.2010 , Issue.29 , pp. 3344-3357
    • Müller, H.1
  • 76
    • 0037218006 scopus 로고    scopus 로고
    • Centrosome aberrations in acute myeloid leukemia are correlated with cytogenetic risk profile
    • Neben K et al (2003) Centrosome aberrations in acute myeloid leukemia are correlated with cytogenetic risk profile. Blood 101: 289-291.
    • (2003) Blood , vol.101 , pp. 289-291
    • Neben, K.1
  • 77
    • 33947374421 scopus 로고    scopus 로고
    • Standard treatments induce antigen-specific immune responses in prostate cancer
    • Nesslinger NJ et al (2007) Standard treatments induce antigen-specific immune responses in prostate cancer. Clin Cancer Res 13: 1493-1502.
    • (2007) Clin Cancer Res , vol.13 , pp. 1493-1502
    • Nesslinger, N.J.1
  • 78
    • 77950387346 scopus 로고    scopus 로고
    • Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
    • Neumann B et al (2010) Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature 464: 721-727.
    • (2010) Nature , vol.464 , pp. 721-727
    • Neumann, B.1
  • 79
    • 0037033788 scopus 로고    scopus 로고
    • Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells
    • Ohta T et al (2002) Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells. J Cell Biol 156: 87-99.
    • (2002) J Cell Biol , vol.156 , pp. 87-99
    • Ohta, T.1
  • 80
    • 67651171191 scopus 로고    scopus 로고
    • Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation
    • Oshimori N et al (2009) Cep72 regulates the localization of key centrosomal proteins and proper bipolar spindle formation. EMBO J 28: 2066-2076.
    • (2009) EMBO J , vol.28 , pp. 2066-2076
    • Oshimori, N.1
  • 82
    • 0036572674 scopus 로고    scopus 로고
    • CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation
    • Ou YY, Mack GJ, Zhang M, Rattner JB (2002) CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation. J Cell Sci 115(Pt 9): 1825-1835.
    • (2002) J Cell Sci , vol.115 , Issue.Pt 9 , pp. 1825-1835
    • Ou, Y.Y.1    Mack, G.J.2    Zhang, M.3    Rattner, J.B.4
  • 84
    • 15544367400 scopus 로고    scopus 로고
    • A physiological view of the primary cilium
    • Praetorius HA, Spring KR (2005) A physiological view of the primary cilium. Annu Rev Physiol 67: 515-529.
    • (2005) Annu Rev Physiol , vol.67 , pp. 515-529
    • Praetorius, H.A.1    Spring, K.R.2
  • 85
    • 22344445826 scopus 로고    scopus 로고
    • Cilia and the cell cycle?
    • Quarmby LM, Parker JD (2005) Cilia and the cell cycle? J Cell Biol 169: 707-710.
    • (2005) J Cell Biol , vol.169 , pp. 707-710
    • Quarmby, L.M.1    Parker, J.D.2
  • 86
    • 0035814937 scopus 로고    scopus 로고
    • Centrosomes: central no more?
    • Raff WJ (2001) Centrosomes: central no more? Curr Biol 11: R159-R161.
    • (2001) Curr Biol , vol.11
    • Raff, W.J.1
  • 87
    • 33644845476 scopus 로고    scopus 로고
    • Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches
    • Reinders Y, Schulz I, Graf R, Sickmann A (2006) Identification of novel centrosomal proteins in Dictyostelium discoideum by comparative proteomic approaches. J Proteome Res 5: 589-598.
    • (2006) J Proteome Res , vol.5 , pp. 589-598
    • Reinders, Y.1    Schulz, I.2    Graf, R.3    Sickmann, A.4
  • 88
    • 34247375933 scopus 로고    scopus 로고
    • Structure and regulation of the human Nek2 centrosomal kinase
    • Rellos P et al (2006) Structure and regulation of the human Nek2 centrosomal kinase. J Biol Chem 282: 6833-6842.
    • (2006) J Biol Chem , vol.282 , pp. 6833-6842
    • Rellos, P.1
  • 89
    • 34247375933 scopus 로고    scopus 로고
    • Structure and regulation of the human Nek2 centrosomal kinase
    • Rellos P et al (2007) Structure and regulation of the human Nek2 centrosomal kinase. J Biol Chem 282: 6833-6842.
    • (2007) J Biol Chem , vol.282 , pp. 6833-6842
    • Rellos, P.1
  • 91
    • 80052822970 scopus 로고    scopus 로고
    • Cancer/testis antigens as potential predictors of biochemical recurrence of prostate cancer following radical prostatectomy
    • Shiraishi T et al (2011) Cancer/testis antigens as potential predictors of biochemical recurrence of prostate cancer following radical prostatectomy. J Transl Med 9: 153.
    • (2011) J Transl Med , vol.9 , pp. 153
    • Shiraishi, T.1
  • 92
    • 80054978334 scopus 로고    scopus 로고
    • A primary microcephaly protein complex forms a ring around parental centrioles
    • Sir JH et al (2011) A primary microcephaly protein complex forms a ring around parental centrioles. Nat Genet 43: 1147-1153.
    • (2011) Nat Genet , vol.43 , pp. 1147-1153
    • Sir, J.H.1
  • 93
    • 40349087260 scopus 로고    scopus 로고
    • Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1
    • Sivasubramaniam S et al (2008) Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1. Genes Dev 22: 587-600.
    • (2008) Genes Dev , vol.22 , pp. 587-600
    • Sivasubramaniam, S.1
  • 94
    • 61849160433 scopus 로고    scopus 로고
    • An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63
    • Smith E, Dejsuphong D, Balestrini A (2009) An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63. Nat Cell Biol 11: 278-285.
    • (2009) Nat Cell Biol , vol.11 , pp. 278-285
    • Smith, E.1    Dejsuphong, D.2    Balestrini, A.3
  • 95
    • 79957612407 scopus 로고    scopus 로고
    • Mutations in CEP57 cause mosaic variegated aneuploidy syndrome
    • Snape K et al (2011) Mutations in CEP57 cause mosaic variegated aneuploidy syndrome. Nat Genet 43: 527-529.
    • (2011) Nat Genet , vol.43 , pp. 527-529
    • Snape, K.1
  • 96
    • 79952782394 scopus 로고    scopus 로고
    • Benzimidazole inhibitors induce a DFG-Out conformation of never in mitosis gene A-related kinase 2 (Nek2) without binding to the back pocket and reveal a nonlinear structure-activity relationship
    • Solanki S et al (2011) Benzimidazole inhibitors induce a DFG-Out conformation of never in mitosis gene A-related kinase 2 (Nek2) without binding to the back pocket and reveal a nonlinear structure-activity relationship. J Med Chem 54: 1626-1639.
    • (2011) J Med Chem , vol.54 , pp. 1626-1639
    • Solanki, S.1
  • 97
    • 34547939469 scopus 로고    scopus 로고
    • Cep97 and CP110 suppress a cilia assembly program
    • Spektor A et al (2007) Cep97 and CP110 suppress a cilia assembly program. Cell 130: 678-690.
    • (2007) Cell , vol.130 , pp. 678-690
    • Spektor, A.1
  • 98
    • 84871742909 scopus 로고    scopus 로고
    • The centriolar satellite protein Cep131 is important for genome stability
    • doi:10.1242/jcs.104059
    • Staples CJ et al (2012) The centriolar satellite protein Cep131 is important for genome stability. J Cell Sci 125(Pt 20): 4770-4779. doi: 10. 1242/jcs. 104059.
    • (2012) J Cell Sci , vol.125 , Issue.Pt 20 , pp. 4770-4779
    • Staples, C.J.1
  • 99
    • 34548280759 scopus 로고    scopus 로고
    • From stem cell to embryo without centrioles
    • Stevens NR et al (2007) From stem cell to embryo without centrioles. Curr Biol 17: 1498-1503.
    • (2007) Curr Biol , vol.17 , pp. 1498-1503
    • Stevens, N.R.1
  • 100
    • 79953892742 scopus 로고    scopus 로고
    • Remote thioredoxin recognition using evolutionary conservation and structural dynamics
    • Tang GW, Altman RB (2011) Remote thioredoxin recognition using evolutionary conservation and structural dynamics. Structure 19: 461-470.
    • (2011) Structure , vol.19 , pp. 461-470
    • Tang, G.W.1    Altman, R.B.2
  • 101
    • 84863255226 scopus 로고    scopus 로고
    • A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants
    • Tao et al (2012) A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. Carcinogenesis 33: 598-603.
    • (2012) Carcinogenesis , vol.33 , pp. 598-603
    • Tao1
  • 102
    • 84863394227 scopus 로고    scopus 로고
    • Genetic risk of hepatocellular carcinoma in patients with hepatitis C virus: a case control study
    • Tomoda T et al (2012) Genetic risk of hepatocellular carcinoma in patients with hepatitis C virus: a case control study. J Gastroenterol Hepatol 27: 797-804.
    • (2012) J Gastroenterol Hepatol , vol.27 , pp. 797-804
    • Tomoda, T.1
  • 103
    • 65649100187 scopus 로고    scopus 로고
    • Cep76, a centrosomal protein that specifically restrains centriole reduplication
    • Tsang WY et al (2009) Cep76, a centrosomal protein that specifically restrains centriole reduplication. Dev Cell 16: 649-660.
    • (2009) Dev Cell , vol.16 , pp. 649-660
    • Tsang, W.Y.1
  • 104
    • 66349104548 scopus 로고    scopus 로고
    • The augmin complex plays a critical role in spindle microtubule generation for mitotic progression andcytokinesis in human cells
    • Uehara R, Nozawa RS, Tomioka A, Petry S, Vale RD, Obuse C, Goshima G (2009) The augmin complex plays a critical role in spindle microtubule generation for mitotic progression andcytokinesis in human cells. Proc Natl Acad Sci USA 106: 6998-7003.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 6998-7003
    • Uehara, R.1    Nozawa, R.S.2    Tomioka, A.3    Petry, S.4    Vale, R.D.5    Obuse, C.6    Goshima, G.7
  • 105
    • 69249087271 scopus 로고    scopus 로고
    • The peptidyl-prolyl isomerase Pin1 regulates cytokinesis through Cep55
    • van der Horst A, Khanna KK (2009) The peptidyl-prolyl isomerase Pin1 regulates cytokinesis through Cep55. Cancer Res 69: 6651-6659.
    • (2009) Cancer Res , vol.69 , pp. 6651-6659
    • van der Horst, A.1    Khanna, K.K.2
  • 106
    • 77954615930 scopus 로고    scopus 로고
    • Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex
    • Wang Z et al (2010) Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex. J Biol Chem 285: 22658-22665.
    • (2010) J Biol Chem , vol.285 , pp. 22658-22665
    • Wang, Z.1
  • 108
    • 78149250139 scopus 로고    scopus 로고
    • Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization
    • Whelligan DK et al (2010) Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization. J Med Chem 53: 7682-7698.
    • (2010) J Med Chem , vol.53 , pp. 7682-7698
    • Whelligan, D.K.1
  • 109
    • 0031750102 scopus 로고    scopus 로고
    • Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry
    • Wigge PA, Jensen ON, Holmes S, Soues S, Mann M, Kilmartin JV (1998) Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J Cell Biol 141: 967-977.
    • (1998) J Cell Biol , vol.141 , pp. 967-977
    • Wigge, P.A.1    Jensen, O.N.2    Holmes, S.3    Soues, S.4    Mann, M.5    Kilmartin, J.V.6
  • 110
    • 63849188695 scopus 로고    scopus 로고
    • Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos
    • Wilkinson CJ, Carl M, Harris WA (2009) Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. BMC Cell Biol 10: 17.
    • (2009) BMC Cell Biol , vol.10 , pp. 17
    • Wilkinson, C.J.1    Carl, M.2    Harris, W.A.3
  • 111
    • 17644399484 scopus 로고    scopus 로고
    • Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings
    • Woods CG, Bond J, Enard W (2005) Autosomal recessive primary microcephaly (MCPH): a review of clinical, molecular, and evolutionary findings. Am J Hum Genet 76: 717-728.
    • (2005) Am J Hum Genet , vol.76 , pp. 717-728
    • Woods, C.G.1    Bond, J.2    Enard, W.3
  • 112
    • 34548857062 scopus 로고    scopus 로고
    • Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase
    • Wu W et al (2007) Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase. J Biol Chem 282: 26431-26440.
    • (2007) J Biol Chem , vol.282 , pp. 26431-26440
    • Wu, W.1
  • 113
    • 78049332008 scopus 로고    scopus 로고
    • Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture
    • Yu TW et al (2010) Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture. Nat Genet 42(11): 1015-1020.
    • (2010) Nat Genet , vol.42 , Issue.11 , pp. 1015-1020
    • Yu, T.W.1
  • 114
    • 65949102982 scopus 로고    scopus 로고
    • CDK5RAP2 is required for spindle checkpoint function
    • Zhang X et al (2009) CDK5RAP2 is required for spindle checkpoint function. Cell Cycle 8: 1206-1216.
    • (2009) Cell Cycle , vol.8 , pp. 1206-1216
    • Zhang, X.1
  • 115
    • 33748334324 scopus 로고    scopus 로고
    • Cep55, a microtubule-bundling protein, associates with centralspindlin to control the midbody integrity and cell abscission during cytokinesis
    • Zhao WM, Seki A, Fang G (2006) Cep55, a microtubule-bundling protein, associates with centralspindlin to control the midbody integrity and cell abscission during cytokinesis. Mol Biol Cell 17: 3881-3896.
    • (2006) Mol Biol Cell , vol.17 , pp. 3881-3896
    • Zhao, W.M.1    Seki, A.2    Fang, G.3
  • 116
    • 67649654451 scopus 로고    scopus 로고
    • Centrosome function in cancer: guilty or innocent?
    • Zyss D, Gergely F (2009) Centrosome function in cancer: guilty or innocent? Trends Cell Biol 19: 334-346.
    • (2009) Trends Cell Biol , vol.19 , pp. 334-346
    • Zyss, D.1    Gergely, F.2


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