CaV2.1 ablation in cortical interneurons selectively impairs fast-spiking basket cells and causes generalized seizures

Annals of Neurology

Volumn 74, Issue 2, 2013, Pages 209-222

  Rossignol, Elsa ^a,b   Kruglikov, Illya ^a   Van Den Maagdenberg, Arn M J M ^c   Rudy, Bernardo ^a   Fishell, Gord ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MONTREAL   (Canada)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CALRETININ; CAV2.1 PROTEIN; ENHANCED GREEN FLUORESCENT PROTEIN; PARVALBUMIN; SOMATOSTATIN; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; 4 AMINOBUTYRIC ACID; CALCIUM CHANNEL N TYPE; VOLTAGE DEPENDENT CALCIUM CHANNEL (P Q TYPE); VOLTAGE-DEPENDENT CALCIUM CHANNEL (P-Q TYPE);

ALLELE; ANIMAL TISSUE; ARTICLE; CELL POPULATION; CONTROLLED STUDY; DISEASE SEVERITY; ELECTROENCEPHALOGRAPHY; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; GENE FUNCTION; HYPERPOLARIZATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTERNEURON; LOSS OF FUNCTION MUTATION; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; OPTOGENETICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; SOMNOLENCE; THALAMOCORTICAL TRACT; TONIC CLONIC SEIZURE; ANIMAL; BRAIN CORTEX; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SEIZURE; TRANSGENIC MOUSE;

ANIMALS; CALCIUM CHANNELS, N-TYPE; CEREBRAL CORTEX; GAMMA-AMINOBUTYRIC ACID; INTERNEURONS; MICE; MICE, TRANSGENIC; MUTATION; PARVALBUMINS; PHENOTYPE; SEIZURES; SOMATOSTATIN;

EID: 84884908972     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.23913     Document Type: Article

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