Impaired fast-spiking, suppressed cortical inhibition, and increased susceptibility to seizures in mice lacking Kv3.2 K+ channel proteins

Journal of Neuroscience

Volumn 20, Issue 24, 2000, Pages 9071-9085

  Lau, David ^a   De Miera, Eleazar Vega Saenz ^a   Contreras, Diego ^b   Ozaita, Ander ^a   Harvey, Michael ^a   Chow, Alan ^a   Noebels, Jeffrey L ^c   Paylor, Richard ^c   Morgan, James I ^d   Leonard, Christopher S ^e   Rudy, Bernardo ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Epilepsy; Fast spiking; GABA; High frequency firing; K+ channels; Knock out inhibitory interneurons; Neocortex; Seizure susceptibility

Indexed keywords

POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; EMBRYO; EPILEPSY; GENE DISRUPTION; GENE TARGETING; INTERNEURON; MOUSE; NEOCORTEX; NERVE CELL EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEIZURE SUSCEPTIBILITY; SPIKE;

EID: 0034671402     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-24-09071.2000     Document Type: Article

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