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Volumn 86, Issue 2, 2013, Pages 317-328

Autophagic cell death induced by resveratrol depends on the Ca2+/AMPK/mTOR pathway in A549 cells

Author keywords

A549; Autophagy; Cell death; Resveratrol

Indexed keywords

3 METHYLADENINE; ADENYLATE KINASE; AUTOPHAGY PROTEIN 5; BAFILOMYCIN A1; BECLIN 1; CALCIUM ION; DANSYLCADAVERINE; FURA 2 ACETOXYMETHYL ESTER; MAMMALIAN TARGET OF RAPAMYCIN; RESVERATROL; SMALL INTERFERING RNA;

EID: 84884903357     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.05.003     Document Type: Article
Times cited : (74)

References (46)
  • 1
    • 33847638137 scopus 로고    scopus 로고
    • Estimates of the cancer incidence and mortality in Europe in 2006
    • DOI 10.1093/annonc/mdl498
    • Ferlay J, Autier P, Boniol M, Heanue M, Colombet M, Boyle P. Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol 2007;18:581-92. (Pubitemid 46359643)
    • (2007) Annals of Oncology , vol.18 , Issue.3 , pp. 581-592
    • Ferlay, J.1    Autier, P.2    Boniol, M.3    Heanue, M.4    Colombet, M.5    Boyle, P.6
  • 3
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • DOI 10.1101/gad.1599207
    • Mizushima N. Autophagy: process and function. Genes Dev 2007;21:2861-73. (Pubitemid 350133435)
    • (2007) Genes and Development , vol.21 , Issue.22 , pp. 2861-2873
    • Mizushima, N.1
  • 4
    • 74949090299 scopus 로고    scopus 로고
    • An overview of the molecular mechanism of autophagy
    • Yang Z, Klionsky DJ. An overview of the molecular mechanism of autophagy. Curr Top Microbiol Immunol 2009;335:1-32.
    • (2009) Curr Top Microbiol Immunol , vol.335 , pp. 1-32
    • Yang, Z.1    Klionsky, D.J.2
  • 6
    • 27644466759 scopus 로고    scopus 로고
    • Autophagy and signaling: Their role in cell survival and cell death
    • DOI 10.1038/sj.cdd.4401751, PII 4401751
    • Codogno P, Meijer A. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 2005;12:1509-18. (Pubitemid 41553987)
    • (2005) Cell Death and Differentiation , vol.12 , Issue.SUPPL. 2 , pp. 1509-1518
    • Codogno, P.1    Meijer, A.J.2
  • 8
    • 42049087592 scopus 로고    scopus 로고
    • Autophagy: For better or for worse, in good times or in bad times..
    • DOI 10.2174/156652408783769634
    • Lerena C, Calligaris SD, Colombo MI. Autophagy: for better or for worse, in good times or in bad times. Curr Mol Med 2008;8:92-101. (Pubitemid 351516829)
    • (2008) Current Molecular Medicine , vol.8 , Issue.2 , pp. 92-101
    • Lerena, C.1    Calligaris, S.D.2    Colombo, M.I.3
  • 9
    • 33745192802 scopus 로고    scopus 로고
    • Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
    • Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006;441:885-9.
    • (2006) Nature , vol.441 , pp. 885-889
    • Hara, T.1    Nakamura, K.2    Matsui, M.3    Yamamoto, A.4    Nakahara, Y.5    Suzuki-Migishima, R.6
  • 10
    • 33745713171 scopus 로고    scopus 로고
    • Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
    • Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G, et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 2006;10:51-64.
    • (2006) Cancer Cell , vol.10 , pp. 51-64
    • Degenhardt, K.1    Mathew, R.2    Beaudoin, B.3    Bray, K.4    Anderson, D.5    Chen, G.6
  • 11
    • 76249124608 scopus 로고    scopus 로고
    • Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation
    • Puissant A, Robert G, Fenouille N, Luciano F, Cassuto JP, Raynaud S, et al. Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. Cancer Res 2010;70:1042-52.
    • (2010) Cancer Res , vol.70 , pp. 1042-1052
    • Puissant, A.1    Robert, G.2    Fenouille, N.3    Luciano, F.4    Cassuto, J.P.5    Raynaud, S.6
  • 12
    • 67549135481 scopus 로고    scopus 로고
    • Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy
    • Laane E, Tamm KP, Buentke E, Ito K, Khahariza P, Oscarsson J, et al. Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy. Cell Death Differ 2009;16:1018-29.
    • (2009) Cell Death Differ , vol.16 , pp. 1018-1029
    • Laane, E.1    Tamm, K.P.2    Buentke, E.3    Ito, K.4    Khahariza, P.5    Oscarsson, J.6
  • 13
    • 0026651085 scopus 로고
    • Wine, alcohol, platelets, and the French paradox for coronary heart disease
    • Renaud S, de Lorgeril M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 1992;339:1523-6.
    • (1992) Lancet , vol.339 , pp. 1523-1526
    • Renaud, S.1    De Lorgeril, M.2
  • 15
    • 67649158904 scopus 로고    scopus 로고
    • Mechanisms of apoptotic effects induced by resveratrol, dibenzoylmethane, and their analogues on human lung carcinoma cells
    • Weng CJ, Yang YT, Ho CT, Yen GC. Mechanisms of apoptotic effects induced by resveratrol, dibenzoylmethane, and their analogues on human lung carcinoma cells. J Agric Food Chem 2009;57:5235-43.
    • (2009) J Agric Food Chem , vol.57 , pp. 5235-5243
    • Weng, C.J.1    Yang, Y.T.2    Ho, C.T.3    Yen, G.C.4
  • 16
    • 74549213817 scopus 로고    scopus 로고
    • 4-Chloro-3, 5-dihydroxystilbene, a resveratrol derivative, induces lung cancer cell death
    • Wu J, Tsai K, Shee J, Li Y, Chen C, Chuang J, et al. 4-Chloro-3, 5-dihydroxystilbene, a resveratrol derivative, induces lung cancer cell death. Acta Pharmacol Sin 2010;31:81-92.
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 81-92
    • Wu, J.1    Tsai, K.2    Shee, J.3    Li, Y.4    Chen, C.5    Chuang, J.6
  • 17
    • 33745808321 scopus 로고    scopus 로고
    • Resveratrol-induced apoptosis is enhanced in acute lymphoblastic leukemia cells by modulation of the mitochondrial permeability transition pore
    • DOI 10.1016/j.canlet.2005.09.001, PII S0304383505008049
    • Zunino SJ, Storms DH. Resveratrol-induced apoptosis is enhanced in acute lymphoblastic leukemia cells by modulation of the mitochondrial permeability transition pore. Cancer Lett 2006;240:123-34. (Pubitemid 44037172)
    • (2006) Cancer Letters , vol.240 , Issue.1 , pp. 123-134
    • Zunino, S.J.1    Storms, D.H.2
  • 18
    • 51049117574 scopus 로고    scopus 로고
    • ERK1/2 activation is required for resveratrol-induced apoptosis in MDA-MB-231 cells
    • Nguyen TH, Mustafa FB, Pervaiz S, Ng F, Lim L. ERK1/2 activation is required for resveratrol-induced apoptosis in MDA-MB-231 cells. Int J Oncol 2008;33: 81-92.
    • (2008) Int J Oncol , vol.33 , pp. 81-92
    • Nguyen, T.H.1    Mustafa, F.B.2    Pervaiz, S.3    Ng, F.4    Lim, L.5
  • 19
    • 79958120468 scopus 로고    scopus 로고
    • GADD45 [alpha] and annexin A1 are involved in the apoptosis of HL-60 induced by resveratrol
    • Li G, He S, Chang L, Lu H, Zhang H, Chiu J. GADD45 [alpha] and annexin A1 are involved in the apoptosis of HL-60 induced by resveratrol. Phytomedicine 2011;18:704-9.
    • (2011) Phytomedicine , vol.18 , pp. 704-709
    • Li, G.1    He, S.2    Chang, L.3    Lu, H.4    Zhang, H.5    Chiu, J.6
  • 20
    • 79955676537 scopus 로고    scopus 로고
    • Induction of autophagy by drugresistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics
    • O'Donovan TR, O'Sullivan GC, McKenna SL. Induction of autophagy by drugresistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics. Autophagy 2011;7: 509-24.
    • (2011) Autophagy , vol.7 , pp. 509-524
    • O'Donovan, T.R.1    O'Sullivan, G.C.2    McKenna, S.L.3
  • 22
    • 34248583762 scopus 로고    scopus 로고
    • Methods for monitoring autophagy from yeast to human
    • Klionsky DJ, Cuervo AM, Seglen PO. Methods for monitoring autophagy from yeast to human. Autophagy 2007;3:181-206. (Pubitemid 46752679)
    • (2007) Autophagy , vol.3 , Issue.3 , pp. 181-206
    • Klionsky, D.J.1    Cuervo, A.M.2    Seglen, P.O.3
  • 23
    • 0028836002 scopus 로고
    • Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles
    • Biederbick A, Kern HF, Elsasser HP. Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. Eur J Cell Biol 1995;66:3-14.
    • (1995) Eur J Cell Biol , vol.66 , pp. 3-14
    • Biederbick, A.1    Kern, H.F.2    Elsasser, H.P.3
  • 24
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000;19:5720-8.
    • (2000) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6
  • 25
    • 0025195515 scopus 로고
    • 2+ in cultured arterial smooth muscle cells using Fura-2 and digital imaging microscopy
    • Goldman W, Bova S, Blaustein M. Measurement of intracellular Ca2+ in cultured arterial smooth muscle cells using Fura-2 and digital imaging microscopy. Cell Calcium 1990;11:221-31. (Pubitemid 20095545)
    • (1990) Cell Calcium , vol.11 , Issue.2-3 , pp. 221-231
    • Goldman, W.F.1    Bova, S.2    Blaustein, M.P.3
  • 26
    • 47249094223 scopus 로고    scopus 로고
    • Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells
    • DOI 10.1038/cdd.2008.51, PII CDD200851
    • Scarlatti F, Maffei R, Beau I, Codogno P, Ghidoni R. Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells. Cell Death Differ 2008;15:1318-29. (Pubitemid 351984760)
    • (2008) Cell Death and Differentiation , vol.15 , Issue.8 , pp. 1318-1329
    • Scarlatti, F.1    Maffei, R.2    Beau, I.3    Codogno, P.4    Ghidoni, R.5
  • 27
    • 0020354209 scopus 로고
    • Protein turnover and proliferation. Failure of SV-3T3 cells to increase lysosomal proteinases, increase protein degradation and cease net protein accumulation
    • Lockwood TD, Minassian IA. Protein turnover and proliferation. Failure of SV- 3T3 cells to increase lysosomal proteinases, increase protein degradation and cease net protein accumulation. Biochem J 1982;206:251-8. (Pubitemid 13227555)
    • (1982) Biochemical Journal , vol.206 , Issue.2 , pp. 251-258
    • Lockwood, T.D.1    Minassian, I.A.2
  • 28
    • 2642553881 scopus 로고    scopus 로고
    • Regulation of an ATG7-beclin 1 program of autophaglic cell death by caspase-8
    • DOI 10.1126/science.1096645
    • Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S, et al. Regulation of an ATG7- Beclin 1 program of autophagic cell death by caspase-8. Science 2004;304:1500-2. (Pubitemid 38720930)
    • (2004) Science , vol.304 , Issue.5676 , pp. 1500-1502
    • Yu, L.1    Alva, A.2    Su, H.3    Dutt, P.4    Freundt, E.5    Welsh, S.6    Baehrecke, E.H.7    Lenardo, M.J.8
  • 30
    • 33745150462 scopus 로고    scopus 로고
    • Ribosomal protein S6 phosphorylation: From protein synthesis to cell size
    • DOI 10.1016/j.tibs.2006.04.003, PII S0968000406001137
    • Ruvinsky I, Meyuhas O. Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. Trends Biochem Sci 2006;31:342-8. (Pubitemid 43903237)
    • (2006) Trends in Biochemical Sciences , vol.31 , Issue.6 , pp. 342-348
    • Ruvinsky, I.1    Meyuhas, O.2
  • 31
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion: Molecular mechanisms and biological functions of autophagy
    • DOI 10.1016/S1534-5807(04)00099-1, PII S1534580704000991
    • Levine B, Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 2004;6:463-77. (Pubitemid 38456176)
    • (2004) Developmental Cell , vol.6 , Issue.4 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 34
    • 20844451123 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
    • DOI 10.1016/j.cmet.2004.12.003, PII S1550413104000099
    • Kahn BB, Alquier T, Carling D, Hardie DG. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 2005;1:15-25. (Pubitemid 43960587)
    • (2005) Cell Metabolism , vol.1 , Issue.1 , pp. 15-25
    • Kahn, B.B.1    Alquier, T.2    Carling, D.3    Hardie, D.G.4
  • 37
    • 34250891313 scopus 로고    scopus 로고
    • AMP-activated protein kinase: A universal regulator of autophagy?
    • Hoyer-Hansen M, Jaattela M. AMP-activated protein kinase: a universal regulator of autophagy. Autophagy 2007;3:381-3. (Pubitemid 46986350)
    • (2007) Autophagy , vol.3 , Issue.4 , pp. 381-383
    • Hoyer-Hansen, M.1    Jaattela, M.2
  • 38
    • 48249102662 scopus 로고    scopus 로고
    • Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients
    • Koivunen J, Kim J, Lee J, Rogers A, Park J, Zhao X, et al. Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients. Br J Cancer 2008;99:245-52.
    • (2008) Br J Cancer , vol.99 , pp. 245-252
    • Koivunen, J.1    Kim, J.2    Lee, J.3    Rogers, A.4    Park, J.5    Zhao, X.6
  • 39
    • 36348997653 scopus 로고    scopus 로고
    • Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer
    • DOI 10.1124/mol.107.039040
    • Sareen D, Darjatmoko SR, Albert DM, Polans AS. Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer. Mol Pharmacol 2007;72:1466-75. (Pubitemid 350146084)
    • (2007) Molecular Pharmacology , vol.72 , Issue.6 , pp. 1466-1475
    • Sareen, D.1    Darjatmoko, S.R.2    Albert, D.M.3    Polans, A.S.4
  • 40
    • 79251534395 scopus 로고    scopus 로고
    • Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes
    • Jia W, Pua HH, Li QJ, He YW. Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes. J Immunol 2011;186:1564-74.
    • (2011) J Immunol , vol.186 , pp. 1564-1574
    • Jia, W.1    Pua, H.H.2    Li, Q.J.3    He, Y.W.4
  • 41
    • 34547640515 scopus 로고    scopus 로고
    • 2+ and mCICR-mediated MPT activation in HepG2 cells
    • DOI 10.1007/s11010-007-9431-8
    • Ma X, Tian X, Huang X, Yan F, Qiao D. Resveratrol-induced mitochondrial dysfunction and apoptosis are associated with Ca2+ and mCICR-mediated MPT activation in HepG2 cells. Mol Cell Biochem 2007;302:99-109. (Pubitemid 47202325)
    • (2007) Molecular and Cellular Biochemistry , vol.302 , Issue.1-2 , pp. 99-109
    • Ma, X.1    Tian, X.2    Huang, X.3    Yan, F.4    Qiao, D.5
  • 42
    • 56549125810 scopus 로고    scopus 로고
    • Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway
    • Wang S, Shih Y, Ko W, Wei YH, Shih C. Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway. Cell Mol Life Sci 2008;65:3640-52.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3640-3652
    • Wang, S.1    Shih, Y.2    Ko, W.3    Wei, Y.H.4    Shih, C.5
  • 43
    • 79952196841 scopus 로고    scopus 로고
    • Apoptosis and autophagy: Decoding calcium signals that mediate life or death
    • Harr MW, Distelhorst CW. Apoptosis and autophagy: decoding calcium signals that mediate life or death. Cold Spring Harb Perspect Biol 2010;2:a005579.
    • (2010) Cold Spring Harb Perspect Biol , vol.2
    • Harr, M.W.1    Distelhorst, C.W.2
  • 44
    • 0029741890 scopus 로고    scopus 로고
    • Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: The role of autophagy
    • Bursch W, Ellinger A, Kienzl H, Torok L, Pandey S, Sikorska M, et al. Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy. Carcinogenesis 1996;17:1595-607. (Pubitemid 26280381)
    • (1996) Carcinogenesis , vol.17 , Issue.8 , pp. 1595-1607
    • Bursch, W.1    Ellinger, A.2    Kienzl, H.3    Torok, L.4    Pandey, S.5    Sikorska, M.6    Walker, R.7    Hermann, R.S.8
  • 46
    • 17144427728 scopus 로고    scopus 로고
    • Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
    • Takeuchi H, Kondo Y, Fujiwara K, Kanzawa T, Aoki H, Mills GB, et al. Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. Cancer Res 2005;65:3336-46. (Pubitemid 40524618)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3336-3346
    • Takeuchi, H.1    Kondo, Y.2    Fujiwara, K.3    Kanzawa, T.4    Aoki, H.5    Mills, G.B.6    Kondo, S.7


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