4'-Chloro-3,5-dihydroxystilbene, a resveratrol derivative, induces lung cancer cell death

Acta Pharmacologica Sinica

Volumn 31, Issue 1, 2010, Pages 81-92

  Wu, Jin Yi ^a   Tsai, Kun Wei ^b   Shee, Jia Jen ^c   Li, Yi Zhen ^a   Chen, Ching Hsein ^a   Chuang, Jing Jing ^a   Liu, Yi Wen ^a  

^a NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^b BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

4 chloro 3,5 dihydroxystilbene; Antitumor effects; Apoptosis; Lung adenocarcinoma A549 cells; Resveratrol derivative

Indexed keywords

4' CHLORO 3,5 DIHYDROXYSTILBENE; ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEASOME; REACTIVE OXYGEN METABOLITE; RESVERATROL; STILBENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PH; CELL VACUOLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME DEGRADATION; FEMALE; HUMAN; HUMAN CELL; IC 50; LUNG ADENOCARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NEWBORN; NONHUMAN; TUMOR XENOGRAFT;

ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL DEATH; CELL LINE, TUMOR; FEMALE; GREEN FLUORESCENT PROTEINS; HUMANS; INHIBITORY CONCENTRATION 50; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES; STILBENES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 74549213817     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.182     Document Type: Article

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