64-Channel uwb wireless neural vector analyzer soc with a closed-loop phase synchrony-triggered neurostimulator

IEEE Journal of Solid-State Circuits

Volumn 48, Issue 10, 2013, Pages 2494-2510

  Abdelhalim, Karim ^b   Jafari, Hamed Mazhab ^b   Kokarovtseva, Larysa ^a   Velazquez, Jose Luis Perez ^a   Genov, Roman ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Closed loop; closed loop SoC; early seizure detection; implantable wireless SoC; mixed signal FIR filters; neural recording; neural stimulation; neural vector analyzer; phase synchronization

Indexed keywords

CLOSED-LOOP; MIXED SIGNAL; NEURAL RECORDINGS; NEURAL STIMULATIONS; NEURAL VECTOR ANALYZER; PHASE SYNCHRONIZATION; SEIZURE DETECTION; WIRELESS SOC;

APPLICATION SPECIFIC INTEGRATED CIRCUITS; ELECTROPHYSIOLOGY; FIR FILTERS; MAMMALS; NEUROPHYSIOLOGY; SIGNAL DETECTION;

ULTRA-WIDEBAND (UWB);

EID: 84884704988     PISSN: 00189200     EISSN: None     Source Type: Journal    
DOI: 10.1109/JSSC.2013.2272952     Document Type: Article

References (42)

1. A. Schnitzler and J. Gross, "Normal and pathological oscillatory communication in the brain," Nature Reviews Neuroscience, vol. 6, no. 4, pp. 285-296, 2005. (Pubitemid 40469983)
2. P. J. Uhlhaas and W. Singer, "Neural synchrony in brain disorders: Relevance for cognitive dysfunctions and pathophysiology," Neuron, vol. 52, no. 1, pp. 155-168, Oct. 2006. (Pubitemid 44466360)
3. J. Baio, "The size and burden of mental disorders and other disorders of the brain in Europe 2010," European Neuropsychopharmacology, vol. 21, no. 3, pp. 655-679, Sept. 2011.
4. J. Baio, "Prevalence of autism spectrum disorders autism and developmental disabilities monitoring," Morbidity and Mortality Weekly Report, vol. 63, no. 3, pp. 1-19, Mar. 2012.
5. P. J. Uhlhaas and W. Singer, "Abnormal neural oscillations and synchrony in schizophrenia," Nature Neuroscience, vol. 11, pp. 100-113, Feb. 2010.
6. R. T. Canolty, E. Edwards, S. Dalal, M. Soltani, S. S. Nagarajan, H. E. Kirsch, B. Barbaro, and R. T. Knight, "High gamma power is phaselocked to theta oscillations in human neocortex," Science, vol. 313, no. 5793, pp. 1626-1628, Sep. 2006. (Pubitemid 44414034)
7. J. L. P. Velazquez, L. G. Dominguez, V. Nenadovic, and R. A. Wennberg, "Experimental observation of increased fluctuations in an order parameter before epochs of extended brain synchronization," J. Biol. Phys., vol. 37, no. 1, p. 14115, Nov. 2010.
8. F. Mormann, K. Lehnertza, P. Davidb, and C. E. Elgera, "Mean phase coherence as a measure for phase synchronization and its application to the EEG of epilepsy patients," J. Physica D: Nonlinear Phenomena, vol. 144, no. 1, pp. 358-369, Oct. 2000.
9. F. Mormann, R. G. Andrzejak, C. E. Elger, and K. Lehnertz, "Seizure prediction: The long and winding road," J. Neurology, Brain, vol. 130, no. 2, pp. 314-333, Sep. 2007. (Pubitemid 46181087)
10. M. S. Chae, W. Liu, and M. Sivaprakasam, "Design optimization for integrated neural recording systems," IEEE J. Solid-State Circuits, vol. 43, no. 9, pp. 1931-1939, Sep. 2008.
11. H. Gao, R. M. Walker, P. Nuyujukian, K. A. A. Makinwa, K. V. Shenoy, B. Murmann, and T. H. Meng, "HermesE: A 96-channel full data rate direct neural interface in 0.13 m CMOS," IEEE J. Solid-State Circuits, vol. 47, no. 4, pp. 1043-1055, Apr. 2012.
12. S. Lee, H. Lee, M. Kiani, U. Jow, and M. Ghovanloo, "An inductively powered scalable 32-channel wireless neural recording system-on-achip for neuroscience applications," in IEEE Int. Solid-State Circuits Conf. Dig. Tech. Papers, Feb. 2010, pp. 120-121.
13. R. R. Harrison, P. T. Watkins, R. J. Kier, R. O. Lovejoy, D. J. Black, B. Greger, and F. Solzbacher, "A low-power integrated circuit for a wireless 100-electrode neural recording system," IEEE J. Solid-State Circuits, vol. 42, no. 1, pp. 123-133, Jan. 2007. (Pubitemid 46103876)
14. M.Azin, D. J. Guggenmos, S. Barbay, R. J. Nudo, and P.Mohseni, "A battery-powered activity-dependent intracortical microstimulation IC for brain-machine-brain interface," IEEE J. Solid-State Circuits, vol. 46, no. 4, pp. 731-745, Apr. 2011.
15. Z. Xiao, C. Tang, C. Dougherty, and R. Bashirullah, "A 20 W neural recording tag with supply-current-modulated AFE in 0.13 mCMOS," in IEEE Int. Solid-State Circuits Conf. Dig. Tech. Papers, Feb. 2010, pp. 122-123.
16. J. Lee, H. Rhew, D. R. Kipke, and M. P. Flynn, "A 64 channel programmable closed-loop neurostimulator with 8 channel neural amplifier and logarithmic ADC," IEEE J. Solid-State Circuits, vol. 45, no. 9, pp. 1935-1945, Sep. 2010.
17. M. Mollazadeh, K. Murari, G. Cauwenberghs, and N. Thakor, "Micropower CMOS integrated low-noise amplification, filtering, and digitization ofmultimodal neuropotentials," IEEE Trans. Biomed. Circuits Syst., vol. 3, no. 1, pp. 1-10, Feb. 2009.
18. M. Chae, Z. Yang, M. R. Yuce, L. Hoang, and W. Liu, "A 128-channel 6 mW wireless neural recording IC with spike feature extraction and UWB transmitter," IEEE Trans. Neural Syst. Rehabil. Eng., vol. 17, no. 4, pp. 312-321, Aug. 2009.
19. S. B. Lee, H. Lee, M. Kiani, U. Jow, and M. Ghovanloo, "An inductively powered scalable 32-channel wireless neural recording system-on-a-chip for neuroscience applications," IEEE Trans. Biomed. Circuits Syst., vol. 4, no. 6, pp. 360-371, Dec. 2010.
20. A. Bonfanti, M. Ceravolo, G. Zambra, R. Gusmeroli, T. Borghi, A. Spinelli, and A. Lacaita, "A multi-channel low-power IC for neural spike recording with data compression and narrowband 400-MHz MC-FSK wireless transmission," in IEEE European Solid-State Circuits Conf., Sep. 2010.
21. F. Shahrokhi, K. Abdelhalim, D. Serletis, P. Carlen, and R. Genov, "128-channel fully differential digital neural recording and stimulation interface," IEEE Trans. Biomed. Circuits Syst., vol. 4, no. 3, pp. 149-161, June 2010.
22. K. Abdelhalim and R. Genov, "915-MHz wireless 64-channel neural recording SoC with programmable mixed-signal FIR filters," in IEEE European Solid-State Circuits Conf., Sep. 2011, pp. 223-226.
23. J. N. Y. Aziz, K. Abdelhalim, R. Shulyzki, B. L. Bardakjian, M. Derchansky, D. Serletis, P. L. Carlen, and R. Genov, "256-channel neural recording and delta compression microsystem with 3D electrodes," IEEE J. Solid-State Circuits, vol. 44, pp. 995-1005, Mar. 2009.
24. R. Shulyzki, K. Abdelhalim, A. Bagheri, C. M. Florez, P. L. Carlen, and R. Genov, "256-site active neural probe and 64-channel responsive cortical stimulator," in Proc. IEEE Custom Integrated Circuits Conf., Sep. 2011, pp. 1-4.
25. N. Verma, A. Shoeb, J. Bohorquez, J. Dawson, J. Guttag, and A. P. Chandrakasan, "A micro-power EEG acquisition SoC with integrated feature extraction processor for a chronic seizure detection system," IEEE J. Solid-State Circuits, vol. 45, no. 4, pp. 804-816, Apr. 2010.
26. A.Avestruz,W. Santa, D. Carlson,R. Jensen, S. Stanslaski,A.Helfenstine, and T. Denison, "A 5 W/channel spectral analysis IC for chronic bidirectional brain machine interfaces," IEEE J. Solid-State Circuits, vol. 43, no. 12, pp. 3306-3024, Dec. 2008.
27. T.Chen, T. Lee, Y. Chen, T.Ma, T. Chuang, C. Chou,C.Yang, T. Lin, and L. Chen, "1.4 W/channel 16-channel EEG/ECoG processor for smart brain sensor SoC," in IEEE Symp. VLSI Circuits, Jun. 2010, pp. 21-22.
28. J. Yoo, L. Yan, D. El-Damak, M. bin Altaf, A. Shoeb, H. Yoo, and A. Chandrakasan, "An 8-channel scalable EEG acquisition SoC with fully integrated patient specific seizure classification and recording processor," in IEEE Int. Solid-State Circuits Conf. Dig. Tech. Papers, Feb. 2012, pp. 292-293.
29. F. Heer, S. Hafizovic, W. Franks, A. Blau, C. Ziegler, and A. Hierlemann, "CMOS microelectrode array for bidirectional interaction with neuronal networks," IEEE J. Solid-State Circuits, vol. 41, no. 7, pp. 1620-1629, Jul. 2006. (Pubitemid 44109297)
30. K. Abdelhalim, H. M. Jafari, L. Kokarovtseva, J. L. P. Velazquez, and R.Genov, "64-channelUWBwireless neural vector analyzer and phase synchrony-triggered stimulator SoC," in IEEE European Solid-State Circuits Conf., Sep. 2012.
31. K. Abdelhalim, V. Smolyakov, and R. Genov, "Phase-synchronization early epileptic seizure detector VLSI architecture," IEEE Trans. Biomed. Circuits Syst., vol. 5, no. 5, pp. 430-438, Oct. 2011.
32. International Seizure Prediction Project, EEG Database, 2010.
33. K. Abdelhalim and R. Genov, "Compact chopper-stabilized neural amplifier with low-distortion high-pass filter in 0.13 mCMOS," in IEEE Int. Symp. Circuits and Systems, May 2012.
34. J. Xu, R. F. Yazicioglu, B. Grundlehner, P. Harpe, K. A. A. Makinwa, and C. Van Hoof, "A 160 W 8-channel active electrode system for EEG monitoring," IEEE Trans. Biomed. Circuits Syst., vol. 5, no. 6, pp. 555-567, Dec. 2011.
35. P. K. Meher, J. Valls, T. Juang, K. Sridharan, and K. Maharatna, "50 years of CORDIC: Algorithms, architectures, and applications," IEEE Trans. Circuits Syst. I, vol. 56, no. 9, pp. 1893-1906, Sep. 2009.
36. P. P. Mercier, D. C. Daly, and A. P. Chandrakasan, "An energy-efficient all-digital uwb transmitter employing dual capacitively-coupled pulse-shaping drivers," IEEE J. Solid-State Circuits, vol. 44, no. 6, pp. 1679-1688, Jun. 2009.
37. Y. Park and D. Wentzlof, "An all-digital 12 pJ/pulse IR-UWB transmitter synthesized from a standard cell library," IEEE J. Solid-State Circuits, vol. 46, no. 5, pp. 1147-1157, May 2011.
38. P. P. Mercier, M. Bhardwaj, D. C. Daly, and A. P. Chandrakasan, "A low-voltage energy-sampling IR-UWB digital baseband employing quadratic correlation," IEEE J. Solid-State Circuits, vol. 45, no. 6, pp. 1147-1157, Jun. 2010.
39. E. J. Tehovnik, "Electrical stimulation of neural tissue to evoke behavioral responses," J. Neuroscience Methods, vol. 65, pp. 1-17, 1996. (Pubitemid 26106371)
40. B. K. Thurgood, D. J. Warren, N. M. Ledbetter, G. A. Clark, and R. R. Harrison, "A wireless integrated circuit for 100-channel charge-balanced neural stimulation," IEEE Trans. Biomed. Circuits Syst., vol. 3, no. 6, pp. 405-414, Dec. 2009.
41. F. T. Sun, M. J. Morrell, and R. E. Wharen, Jr., "Responsive cortical stimulation for the treatment of epilepsy," J. American Society for Experimental NeuroTherapeutics, vol. 5, no. 1, pp. 68-74, Jan. 2008. (Pubitemid 350299302)
42. K. N. Fountas, J. R. Smith, A. M. Murro, J. Politsky, Y. D. Park, and P. D. Jenkins, "Implantation of a closed-loop stimulation in the management of medically refractory focal epilepsy," Stereotatic and Functional Neural Surgery, vol. 83, no. 3, pp. 153-158, Oct. 2005. (Pubitemid 41797953)