Potential role of epigenetic mechanisms in the regulation of drug metabolism and transport

Drug Metabolism and Disposition

Volumn 41, Issue 10, 2013, Pages 1725-1731

  Ingelman Sundberg, Magnus ^a   Zhong, Xiao Bo ^b   Hankinson, Oliver ^c   Beedanagari, Sudheer ^c   Yu, Ai Ming ^d   Peng, Lai ^b   Osawa, Yoichi ^e  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; 5 METHYLCYTOSINE; ABC TRANSPORTER; CARCINOGEN; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; CYTOCHROME P450 3A4; DIOXIN; DNA; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; DOXORUBICIN; DRUG METABOLIZING ENZYME; HISTONE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE; HISTONE METHYLTRANSFERASE; LONG UNTRANSLATED RNA; METHYL CPG BINDING PROTEIN; MICRORNA; MIXED LINEAGE LEUKEMIA PROTEIN; RIFAMPICIN; SIRTUIN; TRANSCRIPTION FACTOR EZH2; UNTRANSLATED RNA;

ARTICLE; CHROMATIN; CYP1A1 GENE; CYP1B1 GENE; CYP3A4 GENE; DNA METHYLATION; DRUG DISPOSITION; DRUG METABOLISM; DRUG RESPONSE; DRUG TRANSPORT; EPIGENETICS; GENE; GENE INTERACTION; HISTONE MODIFICATION; HUMAN; LIVER DEVELOPMENT; MEDICAL SOCIETY; NONHUMAN; PERSONALIZED MEDICINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYMPOSIUM; UNITED STATES;

ARYL HYDROCARBON HYDROXYLASES; BIOLOGICAL TRANSPORT; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 ENZYME SYSTEM; EPIGENESIS, GENETIC; HUMANS; LIVER; METABOLIC DETOXICATION, DRUG; PHARMACEUTICAL PREPARATIONS; XENOBIOTICS;

EID: 84884686896     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.053157     Document Type: Article

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