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Volumn 69, Issue 45, 2013, Pages 9434-9442
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Development of novel LpxC inhibitors: Chiral-pool synthesis of C-triazolyl glycosides
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Author keywords
C Aryl furanosides; Chiral pool synthesis; Click chemistry; LpxC inhibitors; Stereoselective synthesis; Triazoles
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Indexed keywords
5 (1 BENZYL 1H 1,2,3 TRIAZOL 4 YL) N,3,4 TRIHYDROXYTETRAHYDROFURAN 2 CARBOXAMIDE;
5 (1 HEXYL 1H 1,2,3 TRIAZOL 4 YL) N,3,4 TRIHYDROXYTETRAHYDROFURAN 2 CARBOXAMIDE;
5 [1 (4 FLUOROBENZYL) 1H 1,2,3 TRIAZOL 4 YL) N,3,4 TRIHYDROXYTETRAHYDROFURAN 2 CARBOXAMIDE;
BACTERIAL ENZYME;
CHIR 090;
FURANOSE;
FURANOSIDIC HYDROXAMIC ACID;
GLYCOSIDE;
HYDROXAMIC ACID;
LPXC ENZYME;
MANNOSE;
MONOSACCHARIDE;
N,3,4 TRIHYDROXY 5 (1 PHENETHYL 1H 1,2,3 TRIAZOL 4 YL)TETRAHYDROFURAN 2 CARBOXAMIDE;
N,3,4 TRIHYDROXY 5 (1 PHENYL 1H 1,2,3 TRIAZOL 4 YL)TETRAHYDROFURAN 2 CARBOXAMIDE;
N,3,4 TRIHYDROXY 5 [1 (3 PHENYLPROPYL) 1H 1,2,3 TRIAZOL 4 YL]TETRAHYDROFURAN 2 CARBOXAMIDE;
N,3,4 TRIHYDROXY 5 [1 [4 (TRIFLUOROMETHYL)BENZYL] 1H 1,2,3 TRIAZOL 4 YL]TETRAHYDROFURAN 2 CARBOXAMIDE;
TRIAZOLE DERIVATIVE;
UNCLASSIFIED DRUG;
ANTIBACTERIAL ACTIVITY;
ARTICLE;
BACTERIAL GROWTH;
CONTROLLED STUDY;
CRYSTAL STRUCTURE;
CRYSTALLIZATION;
CYCLOADDITION;
DRUG DESIGN;
DRUG INHIBITION;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ESCHERICHIA COLI;
LIPOPHILICITY;
NONHUMAN;
PRIORITY JOURNAL;
PROTON NUCLEAR MAGNETIC RESONANCE;
STEREOCHEMISTRY;
SUBSTITUTION REACTION;
NEGIBACTERIA;
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EID: 84884670401
PISSN: 00404020
EISSN: 14645416
Source Type: Journal
DOI: 10.1016/j.tet.2013.08.074 Document Type: Article |
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Times cited : (14)
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References (37)
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