|
|
Volumn 359, Issue , 2012, Pages 59-64
|
|
Design and stereoselective synthesis of a C-aryl furanoside as a conformationally constrained CHIR-090 analogue
a
a
|
|
Author keywords
C Glycosides; CHIR 090 analogue; Diphenylacetylenes; LpxC inhibitors
|
|
Indexed keywords
ARYL IODIDES;
C-GLYCOSIDES;
CHIR-090 ANALOGUE;
CHIRAL POOL;
DEACETYLASE;
DIPHENYLACETYLENES;
GRAM-NEGATIVE BACTERIA;
HYDROXAMIC ACIDS;
HYDROXYMYRISTOYL;
N-ACETYLGLUCOSAMINE;
NOVEL ANTIBIOTICS;
NUCLEOPHILIC ATTACK;
ONE POT;
PHENYLLITHIUM;
SONOGASHIRA REACTIONS;
STEREOSELECTIVE SYNTHESIS;
SUBSEQUENT REDUCTION;
ACETYLENE;
ESTERIFICATION;
ESTERS;
IODINE;
ORGANIC ACIDS;
STEREOCHEMISTRY;
STEREOSELECTIVITY;
SUGARS;
3,4 TRIHYDROXY 5 [4 [2 [4 (MORPHOLINOMETHYL)PHENYL]ETHYNYL]PHENYL]TETRAHYDROFURAN 2 CARBOXAMIDE;
ACYLTRANSFERASE;
ALKYNE;
CHIR 090;
ENZYME INHIBITOR;
HYDROXAMIC ACID;
MANNOSE;
UNCLASSIFIED DRUG;
URIDINE DIPHOSPHATE 3 O [3 HYDROXYMYRISTOYL] N ACETYLGLUCOSAMINE DEACETYLASE;
ARTICLE;
CHIRALITY;
DRUG CONFORMATION;
DRUG DESIGN;
DRUG SYNTHESIS;
ESTERIFICATION;
NUCLEOPHILICITY;
ONE POT SYNTHESIS;
OXIDATION;
PRIORITY JOURNAL;
REDUCTION;
SONOGASHIRA REACTION;
STEREOCHEMISTRY;
AMIDOHYDROLASES;
CARBOHYDRATE CONFORMATION;
CHEMISTRY TECHNIQUES, SYNTHETIC;
DRUG DESIGN;
ENZYME INHIBITORS;
GLYCOSIDES;
HYDROXAMIC ACIDS;
STEREOISOMERISM;
SUBSTRATE SPECIFICITY;
THREONINE;
NEGIBACTERIA;
|
|
EID: 84865506557
PISSN: 00086215
EISSN: 1873426X
Source Type: Journal
DOI: 10.1016/j.carres.2012.06.006 Document Type: Article |
|
Times cited : (29)
|
|
References (23)
|
