Colon tumour secretopeptidome: Insights into endogenous proteolytic cleavage events in the colon tumour microenvironment

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1834, Issue 11, 2013, Pages 2396-2407

  Greening, David W ^a   Kapp, Eugene A ^b   Ji, Hong ^a   Speed, Terry P ^b   Simpson, Richard J ^a  

^a LA TROBE UNIVERSITY   (Australia)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Ectodomain; Low molecular weight; Peptidome; Proteolysis; Proteolytic cleavage; Secretome

Indexed keywords

CELL MEMBRANE PROTEIN; CELL SURFACE PROTEIN; PEPTIDE FRAGMENT;

ANGIOGENESIS; ARTICLE; CANCER CELL CULTURE; CELL MEMBRANE; CELL SURFACE; COLORECTAL CANCER; GENE SEQUENCE; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR MODEL;

A DISINTEGRIN AND METALLOPROTEINASE; ADAM; AMYLOID PRECURSOR PROTEIN; APP; BASIGIN; BSG; CALR; CALRETICULIN; CARBOXY-TERMINAL FRAGMENT; CARCINOEMBRYONIC ANTIGEN; CDH1; CEA; CELL SURFACE A33 ANTIGEN; CM; COLORECTAL CANCER; CRC; CROSS-CORRELATION SCORE; CTF; CULTURE MEDIUM; DESMOGLEIN-2; DG; DSG2; DYSTROGLYCAN; ECM; ECTODOMAIN; EPITHELIAL CADHERIN; EXTRACELLULAR MATRIX; FALSE DISCOVERY RATE; FDR; GDF15; GLYCOSYLPHOSPHATIDYLINOSITOL; GLYPICAN-1; GPA33; GPC1; GPI; GROWTH/DIFFERENTIATION FACTOR 15; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HNPCC; I-CLIPS; ICD; IDE; INSULIN DEGRADING ENZYME, INSULYSIN; INTRACELLULAR DOMAIN; INTRAMEMBRANE-CLEAVING PROTEASES; LOW-MOLECULAR WEIGHT; MATRIX METALLOPROTEINASE; MEMBRANE-TYPE MMP; MMP; MT-MMP; N-TERMINAL FRAGMENT; NMWL; NOMINAL MOLECULAR WEIGHT LIMIT; NTF; PEP; PEPTIDE SPECTRAL MATCHES; PEPTIDOME; PLASMA MEMBRANE; PM; POSTERIOR ERROR PROBABILITY; PROTEOLYSIS; PROTEOLYTIC CLEAVAGE; PSM; REGULATED INTRAMEMBRANE PROTEOLYSIS; RIP; SECRETOME; STIC; SUMMED TOTAL ION CURRENT; TGFBI; TIC; TMHMM; TNFRSF9; TOTAL ION CURRENT; TP53I11; TRANSFORMING GROWTH FACTOR-BETA-INDUCED PROTEIN IG-H3; TRANSMEMBRANE HIDDEN MARKOV MODEL; TUMOUR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9; TUMOUR PROTEIN P53-INDUCIBLE PROTEIN 11; XCORR;

AMINO ACID SEQUENCE; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLON; COLONIC NEOPLASMS; GPI-LINKED PROTEINS; HUMANS; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; PROTEOME; PROTEOMICS; SECRETORY PATHWAY; TANDEM MASS SPECTROMETRY; TUMOR MICROENVIRONMENT;

EID: 84884651647     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2013.05.006     Document Type: Article

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