-
1
-
-
33847030736
-
Industrial biotechnology for the production of bio-based chemicals-a cradle-to-grave perspective
-
Hatti-Kaul, R., Tornvall, U., Gustafsson, L. and Borjesson, P. (2007) Industrial biotechnology for the production of bio-based chemicals-a cradle-to-grave perspective . Trends in Biotechnology,25,119-24 .
-
(2007)
Trends in Biotechnology
, vol.25
, pp. 119-24
-
-
Hatti-Kaul, R.1
Tornvall, U.2
Gustafsson, L.3
Borjesson, P.4
-
3
-
-
0035843170
-
Industrial biocatalysis today and tomorrow
-
Schmid, A., Dordick, J.S., Hauer, B., Kiener, A., Wubbolts, M. and Witholt, B. (2001) Industrial biocatalysis today and tomorrow . Nature,409,258-68 .
-
(2001)
Nature
, vol.409
, pp. 258-68
-
-
Schmid, A.1
Dordick, J.S.2
Hauer, B.3
Kiener, A.4
Wubbolts, M.5
Witholt, B.6
-
4
-
-
19144366814
-
Metagenomics and industrial applications
-
Lorenz, P. and Eck, J. (2005) Metagenomics and industrial applications . Nature Reviews. Microbiology,3,510-16 .
-
(2005)
Nature Reviews. Microbiology
, vol.3
, pp. 510-16
-
-
Lorenz, P.1
Eck, J.2
-
5
-
-
3543107224
-
Prospecting for biocatalysts and drugs in the genomes of non-cultured microorganisms
-
Streit, W.R., Daniel, R. and Jaeger, K.E. (2004) Prospecting for biocatalysts and drugs in the genomes of non-cultured microorganisms . Current Opinion in Biotechnology,15,285-90 .
-
(2004)
Current Opinion in Biotechnology
, vol.15
, pp. 285-90
-
-
Streit, W.R.1
Daniel, R.2
Jaeger, K.E.3
-
6
-
-
84889807359
-
Enzyme Assays: High-Throughput Screening
-
Wiley-VCH Verlag GmbH, Weinheim
-
Reymond, J.-L. (2006) Enzyme Assays: High-Throughput Screening, Genetic Selection and Fingerprinting, Wiley-VCH Verlag GmbH, Weinheim .
-
(2006)
Genetic Selection and Fingerprinting
-
-
Reymond, J.-L.1
-
8
-
-
0035009353
-
Directed evolution and the creation of enantioselective biocatalysts
-
Jaeger, K.E., Eggert, T., Eipper, A. and Reetz, M.T. (2001) Directed evolution and the creation of enantioselective biocatalysts . Applied Microbiology and Biotechnology,55,519-30 .
-
(2001)
Applied Microbiology and Biotechnology
, vol.55
, pp. 519-30
-
-
Jaeger, K.E.1
Eggert, T.2
Eipper, A.3
Reetz, M.T.4
-
9
-
-
18044390504
-
Directed evolution: selecting today's biocatalysts
-
Otten, L.G. and Quax, W.J. (2005) Directed evolution: selecting today's biocatalysts . Biomolecular Engineering,22,1-9 .
-
(2005)
Biomolecular Engineering
, vol.22
, pp. 1-9
-
-
Otten, L.G.1
Quax, W.J.2
-
10
-
-
36949009858
-
Developments in directed evolution for improving enzyme functions
-
Sen, S., Dasu, V.V. and Mandal, B. (2007) Developments in directed evolution for improving enzyme functions . Applied Biochemistry and Biotechnology,143,212-23 .
-
(2007)
Applied Biochemistry and Biotechnology
, vol.143
, pp. 212-23
-
-
Sen, S.1
Dasu, V.V.2
Mandal, B.3
-
11
-
-
1942496793
-
Directed evolution by random mutagenesis: a critical evaluatio
-
Marcel Dekker, New York
-
Eggert, T., Jaeger, K.E. and Reetz, M.T. (2004) Directed evolution by random mutagenesis: a critical evaluation, in Enzyme Functionality: Design, Engineering, and Screening (ed. A. Svendsen), Marcel Dekker, New York, pp. 375-390 .
-
(2004)
Enzyme Functionality: Design, Engineering, and Screening (ed. A. Svendsen)
, pp. 375-390
-
-
Eggert, T.1
Jaeger, K.E.2
Reetz, M.T.3
-
12
-
-
0029999325
-
Hypermutagenic PCR involving all four transitions and a sizeable proportion of transversions
-
Vartanian, J.P., Henry, M. and WainHobson, S. (1996) Hypermutagenic PCR involving all four transitions and a sizeable proportion of transversions . Nucleic Acids Research,24,2627-31 .
-
(1996)
Nucleic Acids Research
, vol.24
, pp. 2627-31
-
-
Vartanian, J.P.1
Henry, M.2
WainHobson, S.3
-
13
-
-
33744462656
-
The diversity challenge in directed protein evolution
-
Wong, T.S., Zhurina, D. and Schwaneberg, U. (2006) The diversity challenge in directed protein evolution . Combinatorial Chemistry and High Throughput Screening,9,271-88 .
-
(2006)
Combinatorial Chemistry and High Throughput Screening
, vol.9
, pp. 271-88
-
-
Wong, T.S.1
Zhurina, D.2
Schwaneberg, U.3
-
14
-
-
29144503012
-
A statistical analysis of random mutagenesis methods used for directed protein evolution
-
Wong, T.S., Roccatano, D., Zacharias, M. and Schwaneberg, U. (2006) A statistical analysis of random mutagenesis methods used for directed protein evolution . Journal of Molecular Biology,355,858-71 .
-
(2006)
Journal of Molecular Biology
, vol.355
, pp. 858-71
-
-
Wong, T.S.1
Roccatano, D.2
Zacharias, M.3
Schwaneberg, U.4
-
15
-
-
77952506385
-
Challenges of the genetic code for exploring sequence space in directed protein evolution
-
Wong, T.S., Roccatano, D. and Schwaneberg, U. (2007) Challenges of the genetic code for exploring sequence space in directed protein evolution . Biocatalysis and Biotransformation,25,229-41 .
-
(2007)
Biocatalysis and Biotransformation
, vol.25
, pp. 229-41
-
-
Wong, T.S.1
Roccatano, D.2
Schwaneberg, U.3
-
16
-
-
2342535792
-
Sequence saturation mutagenesis (SeSaM): a novel method for directed evolution
-
Wong, T.S., Tee, K.L., Hauer, B. and Schwaneberg, U. (2004) Sequence saturation mutagenesis (SeSaM): a novel method for directed evolution . Nucleic Acids Research,32, e32 .
-
(2004)
Nucleic Acids Research
, vol.32
-
-
Wong, T.S.1
Tee, K.L.2
Hauer, B.3
Schwaneberg, U.4
-
17
-
-
18144379190
-
Sequence saturation mutagenesis with tunable mutation frequencies
-
Wong, T.S., Tee, K.L., Hauer, B. and Schwaneberg, U. (2005) Sequence saturation mutagenesis with tunable mutation frequencies . Analytical Biochemistry,341,187-9 .
-
(2005)
Analytical Biochemistry
, vol.341
, pp. 187-9
-
-
Wong, T.S.1
Tee, K.L.2
Hauer, B.3
Schwaneberg, U.4
-
18
-
-
0030483509
-
Directed evolution: creating biocatalysts for the future
-
Arnold F.H. (1996) Directed evolution: creating biocatalysts for the future . Chemical Engineering Science,51,5091-102 .
-
(1996)
Chemical Engineering Science
, vol.51
, pp. 5091-102
-
-
Arnold, F.H.1
-
19
-
-
44649102734
-
Improving activity and stability of cutinase towards the anionic detergent AOT by complete saturation mutagenesis
-
Brissos, V., Eggert, T., Cabral, J.M.S. and Jaeger, K.E. (2008) Improving activity and stability of cutinase towards the anionic detergent AOT by complete saturation mutagenesis . Protein Engineering, Design and Selection,21,387-93 .
-
(2008)
Protein Engineering, Design and Selection
, vol.21
, pp. 387-93
-
-
Brissos, V.1
Eggert, T.2
Cabral, J.M.S.3
Jaeger, K.E.4
-
20
-
-
0141645603
-
Creation of a productive, highly enantioselective nitrilase through gene site saturation mutagenesis (GSSM)
-
DeSantis, G., Wong, K., Farwell, B., Chatman, K., Zhu, Z.L., Tomlinson, G., Huang, H.J., Tan, X.Q., Bibbs, L., Chen, P., Kretz, K. and Burk, M.J. (2003) Creation of a productive, highly enantioselective nitrilase through gene site saturation mutagenesis (GSSM) . Journal of the American Chemical Society,125,11476-7 .
-
(2003)
Journal of the American Chemical Society
, vol.125
, pp. 11476-7
-
-
DeSantis, G.1
Wong, K.2
Farwell, B.3
Chatman, K.4
Zhu, Z.L.5
Tomlinson, G.6
Huang, H.J.7
Tan, X.Q.8
Bibbs, L.9
Chen, P.10
Kretz, K.11
Burk, M.J.12
-
21
-
-
0041813141
-
Directed evolution of an enantioselective Bacillus subtilis lipase
-
Funke, S.A., Eipper, A., Reetz, M.T., Otte, N., Thiel, W., Van Pouderoyen, G., Dijkstra, B.W., Jaeger, K.E. and Eggert, T. (2003) Directed evolution of an enantioselective Bacillus subtilis lipase . Biocatalysis and Biotransformation,21,67-73 .
-
(2003)
Biocatalysis and Biotransformation
, vol.21
, pp. 67-73
-
-
Funke, S.A.1
Eipper, A.2
Reetz, M.T.3
Otte, N.4
Thiel, W.5
Van Pouderoyen, G.6
Dijkstra, B.W.7
Jaeger, K.E.8
Eggert, T.9
-
22
-
-
0001121864
-
Rapid evolution of reversible denaturation and elevated melting temperature in a microbial haloalkane dehalogenase
-
Gray, K.A., Richardson, T.H., Kretz, K., Short, J.M., Bartnek, F., Knowles, R., Kan, L., Swanson, P.E. and Robertson, D.E. (2001) Rapid evolution of reversible denaturation and elevated melting temperature in a microbial haloalkane dehalogenase . Advanced Synthesis Catalysis,343,607-17 .
-
(2001)
Advanced Synthesis Catalysis
, vol.343
, pp. 607-17
-
-
Gray, K.A.1
Richardson, T.H.2
Kretz, K.3
Short, J.M.4
Bartnek, F.5
Knowles, R.6
Kan, L.7
Swanson, P.E.8
Robertson, D.E.9
-
23
-
-
0035800615
-
Lipolytic enzymes LipA and LipB from Bacillus subtilis differ in regulation of gene expression, biochemical properties, and three-dimensional structure
-
Eggert, T., van Pouderoyen, G., Dijkstra, B.W. and Jaeger, K.E. (2001) Lipolytic enzymes LipA and LipB from Bacillus subtilis differ in regulation of gene expression, biochemical properties, and three-dimensional structure . FEBS Letters,502,89-92 .
-
(2001)
FEBS Letters
, vol.502
, pp. 89-92
-
-
Eggert, T.1
van Pouderoyen, G.2
Dijkstra, B.W.3
Jaeger, K.E.4
-
24
-
-
0036071674
-
Biochemical properties and three-dimensional structures of two extracellular lipolytic enzymes from Bacillus subtilis
-
Eggert, T., van Pouderoyen, G., Pencreac'h, G., Douchet, I., Verger, R., Dijkstra, B.W. and Jaeger, K.E. (2002) Biochemical properties and three-dimensional structures of two extracellular lipolytic enzymes from Bacillus subtilis . Colloids and Surfaces B: Biointerfaces,26,37-46 .
-
(2002)
Colloids and Surfaces B: Biointerfaces
, vol.26
, pp. 37-46
-
-
Eggert, T.1
van Pouderoyen, G.2
Pencreac'h, G.3
Douchet, I.4
Verger, R.5
Dijkstra, B.W.6
Jaeger, K.E.7
-
25
-
-
0035946913
-
The crystal structure of Bacillus subtilis lipase: a minimal alpha/beta hydrolase fold enzyme
-
van Pouderoyen, G., Eggert, T., Jaeger, K.E. and Dijkstra, B.W. (2001) The crystal structure of Bacillus subtilis lipase: a minimal alpha/beta hydrolase fold enzyme . Journal of Molecular Biology,309,215-26 .
-
(2001)
Journal of Molecular Biology
, vol.309
, pp. 215-26
-
-
van Pouderoyen, G.1
Eggert, T.2
Jaeger, K.E.3
Dijkstra, B.W.4
-
26
-
-
3042629721
-
Novel biocatalysts by identifi cation and design
-
Eggert, T., Leggewie, C., Puls, M., Streit, W., van Pouderoyen, G., Dijkstra, B.W. and Jaeger, K.E. (2004) Novel biocatalysts by identifi cation and design . Biocatalysis and Biotransformation,22,139-44 .
-
(2004)
Biocatalysis and Biotransformation
, vol.22
, pp. 139-44
-
-
Eggert, T.1
Leggewie, C.2
Puls, M.3
Streit, W.4
van Pouderoyen, G.5
Dijkstra, B.W.6
Jaeger, K.E.7
-
28
-
-
0027382306
-
Growth-phase-dependent expression of the lipolytic system of Acinetobacter calcoaceticus Bd413-cloning of a gene encoding one of the esterases
-
Kok, R.G., Christoffels, V.M., Vosman, B. and Hellingwerf, K.J. (1993) Growth-phase-dependent expression of the lipolytic system of Acinetobacter calcoaceticus Bd413-cloning of a gene encoding one of the esterases . Journal of General Microbiology,139,2329-42 .
-
(1993)
Journal of General Microbiology
, vol.139
, pp. 2329-42
-
-
Kok, R.G.1
Christoffels, V.M.2
Vosman, B.3
Hellingwerf, K.J.4
-
29
-
-
3042531902
-
Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity
-
Bocola, M., Otte, N., Jaeger, K.E., Reetz, M.T. and Thiel, W. (2004) Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity . ChemBioChem,5,214-23 .
-
(2004)
ChemBioChem
, vol.5
, pp. 214-23
-
-
Bocola, M.1
Otte, N.2
Jaeger, K.E.3
Reetz, M.T.4
Thiel, W.5
-
30
-
-
33846302851
-
Learning from directed evolution: further lessons from theoretical investigations into cooperative mutations in lipase enantioselectivity
-
Reetz, M.T., Puls, M., Carballeira, J.D., Vogel, A., Jaeger, K.E., Eggert, T., Thiel, W., Bocola, M. and Otte, N. (2007) Learning from directed evolution: further lessons from theoretical investigations into cooperative mutations in lipase enantioselectivity . ChemBioChem,8,106-12 .
-
(2007)
ChemBioChem
, vol.8
, pp. 106-12
-
-
Reetz, M.T.1
Puls, M.2
Carballeira, J.D.3
Vogel, A.4
Jaeger, K.E.5
Eggert, T.6
Thiel, W.7
Bocola, M.8
Otte, N.9
-
31
-
-
34247374701
-
Selection strategies for improved biocatalysts
-
Boersma, Y.L., Dröge, M.J. and Quax, W.J. (2007) Selection strategies for improved biocatalysts . The FEBS Journal,274,2181-95 .
-
(2007)
The FEBS Journal
, vol.274
, pp. 2181-95
-
-
Boersma, Y.L.1
Dröge, M.J.2
Quax, W.J.3
-
32
-
-
30444439246
-
Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection
-
Droge, M.J., Boersma, Y.L., van Pouderoyen, G., Vrenken, T.E., Ruggeberg, C.J., Reetz, M.T., Dijkstra, B.W. and Quax, W.J. (2006) Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection . ChemBioChem,7,149-57 .
-
(2006)
ChemBioChem
, vol.7
, pp. 149-57
-
-
Droge, M.J.1
Boersma, Y.L.2
van Pouderoyen, G.3
Vrenken, T.E.4
Ruggeberg, C.J.5
Reetz, M.T.6
Dijkstra, B.W.7
Quax, W.J.8
-
33
-
-
4143110558
-
Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase
-
Acharya, P., Rajakumara, E., Sankaranarayanan, R. and Rao, N.M. (2004) Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase . Journal of Molecular Biology,341,1271-81 .
-
(2004)
Journal of Molecular Biology
, vol.341
, pp. 1271-81
-
-
Acharya, P.1
Rajakumara, E.2
Sankaranarayanan, R.3
Rao, N.M.4
-
34
-
-
34248567845
-
Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes
-
Reetz, M.T. and Carballeira, J.D. (2007) Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes . Nature Protocols,2,891-903 .
-
(2007)
Nature Protocols
, vol.2
, pp. 891-903
-
-
Reetz, M.T.1
Carballeira, J.D.2
-
35
-
-
33845288649
-
Iterative saturation mutagenesis on the basis of B factors as a strategy for increasing protein thermostability
-
Reetz, M.T., Carballeira, J.D. and Vogel, A. (2006) Iterative saturation mutagenesis on the basis of B factors as a strategy for increasing protein thermostability . Angewandte Chemie-International Edition,45,7745-51 .
-
(2006)
Angewandte Chemie-International Edition
, vol.45
, pp. 7745-51
-
-
Reetz, M.T.1
Carballeira, J.D.2
Vogel, A.3
|